N-Glykosylierung der Gastropoden: Strukturanalyse der Oligosaccharide und Charakterisierung der beteiligten Glykosidasen und Glykosyltransferasen
Abstract
Although some gastropods (phylum mollusca) are used as foodstuff and others are a remarkable pest in agriculture or serve as intermediary hosts for parasites, only little is known about their glycosylation potentials. Therefore this project will elucidate the N-glycosylation patterns of four different snails (water- and land-living animals, with and without shell) and the glycosyltransferases involved in vivo in the biosynthesis of these oligosaccharides will be purified and characterised. With knowledge on the glycosylation abilities of gastropoda it may be possible to establish a new cell culture system, to uncover new means for pest control in some species, or to identify already known allergic carbohydrate epitopes. Furthermore specific exoglycosidases will be purified from snails in a preparative scale, which may be potential tools for glycan analysis.
dx.doi.org
Mitarbeiter*innen
Erika Staudacher
Ao.Univ.-Prof.i.R. Dipl.-Ing.Dr.nat.techn. Erika Staudacher
erika.staudacher@boku.ac.at
Projektleiter*in
01.02.2000 - 31.01.2003
Manfred Pintar
Ass.Prof.i.R. Mag.rer.nat.Dr.phil. Manfred Pintar
manfred.pintar@boku.ac.at
Projektmitarbeiter*in
01.02.2000 - 31.01.2003
BOKU Partner
