Irene Schaffner

Lectures

• Year: 2021 -  Understanding the reaction mechanism of chlorite dismutases: Characterizing protonation states of turnover-associated amino acid residues using neutron cryo-crystallography

  Autoren: Schmidt, D; Schaffner, I; Mlynek, G; Djinovic-Carugo, K; Obinger, C

  Event: MLZ conference 2021: Neutrons for Life Sciences

• Year: 2019 -  Molecular Mechanism of Enzymatic Chlorite Degradation

  Autoren: Obinger, C; Schaffner, I; Schmidt, D; Smulevich, G; Coates, L; Battistuzzi, G; Furtmüller, PG; Hofbauer, S

  Event: 19th International Conference on Biological Inorganic Chemistry 2019

• Year: 2019 -  A LIPOCALIN-BASED ON-SWITCH FOR CONTROLLING CAR T CELLS WITH AN ORALLY AVAILABLE DRUG

  Autoren: Brey, C; Dobersberger, M; Schaffner, I; Mlynek, G; P?hringer, D; Salzer, B; Djinovic-Carugo, K; Obinger, C; Holter, W; Traxlmayr, M; Lehner, M

  Event: International Conference on Lymphocyte Engineering (ICLE)

• Year: 2019 -  Construction of a molecular ON-switch for controlling CAR T cells with an orally available small molecule

  Autoren: Brey, CU; Dobersberger, M; Schaffner, I; Mlynek, G; Pühringer, D; Salzer, B; Djinović-Carugo. K; Obinger, C; Holter, W; Lehner, M; Traxlmayr, MW

  Event: PEGS Boston

• Year: 2019 -  Manipulation of heme environment in the active site of chlorite dismutases and its impact on the enzymatic activity

  Autoren: Schmidt, D; Schaffner, I; Hofbauer, S; Furtmüller PG; Obinger, C

  Event: 19th International Conference on Biological Inorganic Chemistry 2019

• Year: 2018 -  Characterization and comparison of the distal heme environment of dimeric and pentameric chlorite dismutases

  Autoren: Schmidt, D., Schaffner, I., Hofbauer, S., Mlynek, G., Djinović-Carugo, K., Furtmüller, P. G., Obinger, C.

  Event: OxiZymes 2018

• Year: 2018 -  Molecular mechanism of enzymatic chlorite degradation

  Autoren: Obinger, C; Schaffner, I; Smulevich, G; Coates, L; Battistuzzi, G; Furtmüller, P.G; Hofbauer, S;

  Event: Tenth International Conference on Porphyrins and Phthalocyanines (ICPP-10)

• Year: 2016 -  Dye decolorizing peroxidases – a new heme-peroxidase family with ancient roots

  Autoren: Pfanzagl, V; Schaffner, I; Hofbauer, S; Furtmüller, P.G; Obinger, C

  Event: 17th European Congress on Biotechnology ECB17 2016

• Year: 2016 -  High-resultion X-ray and neutron diffration structures and biophysical studies on a novel dimeric chlorite dismutase

  Autoren: Schaffner, I., Mlynek, G., Hofbauer, S., Smulevich, G., Battistuzzi, G., Djinovic-Carugo, K., Furtmüller, P. G., Coates, L., Obinger, C.

  Event: 79th Harden Conference on Oxygen Evolution and Reduction - Common Principles

• Year: 2016 -  Chlorite dismutase: distal heme environment and its role in irreversible enzyme inactivation

  Autoren: Schaffner, I., Hofbauer, S., Mlynek, G., Battistuzzi, G., Djinovic-Carugo, K., Furtmüller, P. G., Obinger, C.

  Event: 13th European Biological Inorganic Chemistry Conference EuroBIC 2016

• Year: 2016 -  Dye decolorizing peroxidases - A new heme-peroxidase family with ancient roots

  Autoren: Pfanzagl, V; Schaffner, I; Hofbauer, S; Furtmuller, P; Obinger, C

  Event: European Congress on Biotechnology 2016

• Year: 2016 -  Coproheme and HemQ

  Autoren: Hofbauer, S., Scheiblbrandner, S., Schaffner, I., Djinović-Carugo, K., Battistuzzi, G., Furtmüller, P. G., Obinger, C.

  Event: 13th European Biological Inorganic Chemistry Conference EuroBIC 2016

• Year: 2016 -  Dioxygen evolution by chlorite dismutase depends on co-ordination of transiently produced hypochlorite to an oxoiron(IV) intermediate

  Autoren: Hofbauer, S., Grünwald-Gruber, C., Schaffner, I., Sündermann, A., Jakopitsch, C., Oostenbrink, C., Djinovic-Carugo, K., Furtmüller, P.G., Obinger, C.

  Event: 79th Harden Conference on Oxygen Evolution and Reduction

• Year: 2016 -  Chlorite dismutase: Combining X-ray/neutron crystallography to investigate structure-function relationships

  Autoren: Schaffner, I; Mlynek, G; Coates, L; Hofbauer, S; Djinović-Carugo, K; Furtmüller, P.G; Obinger, C

  Event: OxiZymes 2016

• Year: 2014 -  Mechanistic studies on a new functional dimeric chlorite dismutase

  Autoren: Schaffner, I; Flego, N; Mlynek, G; Bellei, M; Hofbauer, S; Battistuzzi, G; Djinovic-Carugo, K; Smulevich, G; Furtmuller, PG; Obinger, C

  Event: 12th European Biological Inorganic Chemistry Conference EuroBIC 2014

• Year: 2014 -  Chlorite dismutases and dye-decolorizing peroxidases – similarities and differences within a structural superfamily of heme proteins

  Autoren: Schaffner, I., Hofbauer, S., Furtmueller, P. G., Obinger, C.

  Event: 16th European Congress on Biotechnology 2014

• Year: 2014 -  Biochemical and biophysical characterization of a new functional chlorite dismutase

  Autoren: Schaffner, I., Hofbauer, S., Pirker, K.F., Furtmüller, P.G., Obinger, C.

  Event: OxiZymes 2014

• Year: 2014 -  Understanding the inhibition mechanism of chlorite dismutase from the nitrite-oxidizing bacterium Candidatus Nitrospira defluvii

  Autoren: Hofbauer, S; Gruber, C; Schaffner, I; Pirker, KF; Jakopitsch, C; Sundermann, A; Oostenbrink, C; Furtmuller, PG; Obinger, C

  Event: 12th European Biological Inorganic Chemistry Conference EuroBIC 2014

• Year: 2014 -  Chlorite to chloride and O2 conversion: new lessons from structural and mechanistic investigations of chlorite dismutase

  Autoren: Obinger, C., Hofbauer, S., Schaffner, I., Pirker, K. F., Mlynek, G.,Djinovic-Carugo, K., Battistuzzi, G., Furtmüller, P. G

  Event: 12th European Biological Inorganic Chemistry Conference EuroBIC 2014

• Year: 2014 -  Redox properties of the Fe3+/Fe2+ couple in wild-type and mutated heme chlorite dismutases

  Autoren: Hofbauer, S., Bellei, M., Schaffner, I., Furtmüller, P.G., Obinger, C., Battistuzzi, C.

  Event: OxiZymes 2014

• Year: 2014 -  Mechanism of inhibition of chlorite dismutase

  Autoren: Hofbauer, S., Schaffner, I., Gruber, C., Pirker, K.F., Jakopitsch, C., Sündermann, A., Oostenbrink, C., Furtmüller, P.G., Obinger, C.

  Event: OxiZymes 2014

• Year: 2013 -  Understanding highly stable chlorite dismutase form nitrate-oxidizing bacterium Candidatus “Nitrospira defluvii”

  Autoren: Hofbauer, S., Gruber, C., Pirker, K. F., Schaffner, I., Hagmüller, A., Gysel, K., Mlynek, G., Kostan, J., Bellei, M., Daims, H., Djinovic-Carugo, K. Battistuzzi, G., Furtmüller, P.G. and Obinger, C

  Event: International Conference on Bioinorganic Chemistry ICBIC-16 2013

• Year: 2013 -  Understanding Chlorite Dismutase from Candidatus Nitrospira defluvii

  Autoren: Hofbauer, S; Gruber, C; Pirker, KF; Schaffner, I; Furtmuller, PG; Obinger, C; Hagmuller, A; Gysel, K; Mlynek, G; Kostan, J; Djinovic-Carugo, K; Bellei, M; Battistuzzi, G; Daims, H

  Event: International Conference on Bioinorganic Chemistry ICBIC-16 2013

• Year: 2013 -  Spectroscopic Characterization of wild-type Chlorite Dismutase from Candidatus “Nitrospira defluvii” and selected variants

  Autoren: Hofbauer, S., Flego, N., Schaffner, I., Pirker, K. F., Furtmüller, P. G., Howes, B. D., Obinger, C., Smulevich, G.

  Event: 15th European Conference on the Spectroscopy of Biological Molecules