Biocatalytic production of aldonic acids and enzymatic yoghurt
Abstract
The enzyme cellbiose dehydrogenase is a fungal enzyme containing flavin and heme. The catalytically active dehydrogenase domain catalyses the oxidation of cellobiose to cellobionic acid and lactose to lactobionic acid. The enzyme is a dehydrogenase and only reacts poorly with oxygen. A cellobiose oxidase showing improved activity with oxygen would have advantages with respect to various applications. Generating a CDH variant of Myriococcum thermophilum with increased reactivity with oxygen, the neutral pH activity optimum was maintained. It was shown that this variant can convert lactose in milk. It is the aim of the current project to further improve the enzyme for industrial applications.
Publikationen
Project staff
Dietmar Haltrich
Univ.Prof. Dipl.-Ing. Dr.techn. Dietmar Haltrich
dietmar.haltrich@boku.ac.at
Tel: +43 1 47654-75211
Project Leader
01.08.2018 - 31.07.2018