Protein expression in different Bacillaceae with emphasis on S-layer glycoprotein biosynthesis. (H-00199/98)
Project management Graninger Michael
organizational unit Institute of Nanobiotechnology (NBT)
duration 20.10.1998 to- 31.12.1999
Research project (§ 26 & § 27)
Program none
Funder none
Competencies
Abstract
Glycosylation of S-layer proteins is a common feature among thermophilic Bacillaceae. However, during continuous cultivation of S-layer glycoprotein producing strains frequently a loss of glycosylation was observed. Detailed analysis of this phenomenon using genetic, taxonomic and biochemical methods shall define mechanisms for the change of the phenotype of these strains. As a result the control of the glycosylation process may provide S-layer glycoproteins suitable for biomedicine and biotechnology.
keywords
www.cis.tu-graz.at
Project staff
Paul Messner
Ao.Univ.-Prof.i.R. Dipl.-Ing.Dr.nat.techn. Paul Messner
paul.messner@boku.ac.at
Project Staff
20.10.1998 - 31.12.1999
BOKU partners
Funder
