N-glycosylation in gastropods: Analysis of the oligosaccharide structures and characterisation of the corresponding glycosidases and glycosyltransferases
Abstract
Although some gastropods (phylum mollusca) are used as foodstuff and others are a remarkable pest in agriculture or serve as intermediary hosts for parasites, only little is known about their glycosylation potentials. Therefore this project will elucidate the N-glycosylation patterns of four different snails (water- and land-living animals, with and without shell) and the glycosyltransferases involved in vivo in the biosynthesis of these oligosaccharides will be purified and characterised. With knowledge on the glycosylation abilities of gastropoda it may be possible to establish a new cell culture system, to uncover new means for pest control in some species, or to identify already known allergic carbohydrate epitopes. Furthermore specific exoglycosidases will be purified from snails in a preparative scale, which may be potential tools for glycan analysis.
dx.doi.org
Project staff
Erika Staudacher
Ao.Univ.-Prof.i.R. Dipl.-Ing.Dr.nat.techn. Erika Staudacher
erika.staudacher@boku.ac.at
Project Leader
01.02.2000 - 31.01.2003
Manfred Pintar
Ass.Prof.i.R. Mag.rer.nat.Dr.phil. Manfred Pintar
manfred.pintar@boku.ac.at
Project Staff
01.02.2000 - 31.01.2003
BOKU partners
Funder
