Lipoxysan – a liposomal formulation of SOD for transdermal application
- Biotechnologie
Abstract
Lipoxysanâ a liposomal formulation of the recombinant, human Cu/Zn Superoxide Dismutase, prepared with the Cross-Flow-Injection Techniqueâ, will be optimised and several batches will be prepared in pharmaceutical quality. To proof the potency of this lipsomal fomulation, two clinical trials will be performed. First, a clinical study for the treatment of Peyronie Disease (IPP) will be carried out. The efficacy of Lipoxysan against the inflammatory response will be evaluated. In the second approach, studies with Lipoxysan to reduce post-burn edema and improvement in wound healing will be performed. The treatment will be evaluated in first and second degree burns.
Project staff
Karola Vorauer-Uhl
ao.Univ.Prof. Dipl.-Ing.Dr.nat.techn. Karola Vorauer-Uhl
karola.vorauer-uhl@boku.ac.at
Tel: +43 1 47654-79850
Project Leader
01.01.2000 - 31.12.2002
Hermann Katinger
em.o.Univ.Prof. Dipl.-Ing.Dr. Hermann Katinger
hkating@boku.ac.at
Tel: +43 1 47654-79856
Sub Projectleader
01.01.2000 - 31.12.2002
BOKU partners
External partners
Austrian Academy of Sciences
Doz. Dr. K. Lohner: Inst. Für Biophysik und Röntgenstrukturforschung
partner
Lorenz Böhler Krankenhaus
Doz. Dr. H. Redl, Inst. Für experimentelle Traumatologie
partner
Krankenhaus Lainz, Department für Urologie und Ludwig Boltzmann Institut für Andrologie
Prof. Dr. H. Pflüger, Prof. Dr. C.R. Riedl
partner
Medical University of Graz
Univ. Prof. Dr. W. Aberer, Universitätsklinik für Dermatologie und Venerologie
partner
Medical University of Vienna
Dr. R. Ullrich und Dr. P. Germann
partner