Irene Schaffner
Dipl.-Ing. Dr. Irene Schaffner
Institut BOKU Core Facilities
Institut Institute of Biochemistry (DCH/BC)
Location Muthgasse 11, 1190 Wien
Email irene.schaffner@boku.ac.at
Tel: +43 1 47654-35011
Projects
0 Projects found.
Publications
Knowledge Transfer to Society
Media
Lectures
(2021) Understanding the reaction mechanism of chlorite dismutases: Characterizing protonation states of turnover-associated amino acid residues using neutron cryo-crystallography
Autoren: Schmidt, D; Schaffner, I; Mlynek, G; Djinovic-Carugo, K; Obinger, C
MLZ conference 2021: Neutrons for Life Sciences
(2019) Molecular Mechanism of Enzymatic Chlorite Degradation
Autoren: Obinger, C; Schaffner, I; Schmidt, D; Smulevich, G; Coates, L; Battistuzzi, G; Furtmüller, PG; Hofbauer, S
19th International Conference on Biological Inorganic Chemistry 2019
(2019) A LIPOCALIN-BASED ON-SWITCH FOR CONTROLLING CAR T CELLS WITH AN ORALLY AVAILABLE DRUG
Autoren: Brey, C; Dobersberger, M; Schaffner, I; Mlynek, G; P?hringer, D; Salzer, B; Djinovic-Carugo, K; Obinger, C; Holter, W; Traxlmayr, M; Lehner, M
International Conference on Lymphocyte Engineering (ICLE)
(2019) Manipulation of heme environment in the active site of chlorite dismutases and its impact on the enzymatic activity
Autoren: Schmidt, D; Schaffner, I; Hofbauer, S; Furtmüller PG; Obinger, C
19th International Conference on Biological Inorganic Chemistry 2019
(2018) Characterization and comparison of the distal heme environment of dimeric and pentameric chlorite dismutases
Autoren: Schmidt, D., Schaffner, I., Hofbauer, S., Mlynek, G., Djinović-Carugo, K., Furtmüller, P. G., Obinger, C.
OxiZymes 2018
(2018) Molecular mechanism of enzymatic chlorite degradation
Autoren: Obinger, C; Schaffner, I; Smulevich, G; Coates, L; Battistuzzi, G; Furtmüller, P.G; Hofbauer, S;
Tenth International Conference on Porphyrins and Phthalocyanines (ICPP-10)
(2016) Dye decolorizing peroxidases – a new heme-peroxidase family with ancient roots
Autoren: Pfanzagl, V; Schaffner, I; Hofbauer, S; Furtmüller, P.G; Obinger, C
17th European Congress on Biotechnology ECB17 2016
(2016) High-resultion X-ray and neutron diffration structures and biophysical studies on a novel dimeric chlorite dismutase
Autoren: Schaffner, I., Mlynek, G., Hofbauer, S., Smulevich, G., Battistuzzi, G., Djinovic-Carugo, K., Furtmüller, P. G., Coates, L., Obinger, C.
79th Harden Conference on Oxygen Evolution and Reduction - Common Principles
(2016) Chlorite dismutase: distal heme environment and its role in irreversible enzyme inactivation
Autoren: Schaffner, I., Hofbauer, S., Mlynek, G., Battistuzzi, G., Djinovic-Carugo, K., Furtmüller, P. G., Obinger, C.
13th European Biological Inorganic Chemistry Conference EuroBIC 2016
(2016) Dye decolorizing peroxidases - A new heme-peroxidase family with ancient roots
Autoren: Pfanzagl, V; Schaffner, I; Hofbauer, S; Furtmuller, P; Obinger, C
European Congress on Biotechnology 2016
(2016) Coproheme and HemQ
Autoren: Hofbauer, S., Scheiblbrandner, S., Schaffner, I., Djinović-Carugo, K., Battistuzzi, G., Furtmüller, P. G., Obinger, C.
13th European Biological Inorganic Chemistry Conference EuroBIC 2016
(2016) Dioxygen evolution by chlorite dismutase depends on co-ordination of transiently produced hypochlorite to an oxoiron(IV) intermediate
Autoren: Hofbauer, S., Grünwald-Gruber, C., Schaffner, I., Sündermann, A., Jakopitsch, C., Oostenbrink, C., Djinovic-Carugo, K., Furtmüller, P.G., Obinger, C.
79th Harden Conference on Oxygen Evolution and Reduction
(2016) Chlorite dismutase: Combining X-ray/neutron crystallography to investigate structure-function relationships
Autoren: Schaffner, I; Mlynek, G; Coates, L; Hofbauer, S; Djinović-Carugo, K; Furtmüller, P.G; Obinger, C
OxiZymes 2016
(2014) Mechanistic studies on a new functional dimeric chlorite dismutase
Autoren: Schaffner, I; Flego, N; Mlynek, G; Bellei, M; Hofbauer, S; Battistuzzi, G; Djinovic-Carugo, K; Smulevich, G; Furtmuller, PG; Obinger, C
12th European Biological Inorganic Chemistry Conference EuroBIC 2014
(2014) Chlorite dismutases and dye-decolorizing peroxidases – similarities and differences within a structural superfamily of heme proteins
Autoren: Schaffner, I., Hofbauer, S., Furtmueller, P. G., Obinger, C.
16th European Congress on Biotechnology 2014
(2014) Understanding the inhibition mechanism of chlorite dismutase from the nitrite-oxidizing bacterium Candidatus Nitrospira defluvii
Autoren: Hofbauer, S; Gruber, C; Schaffner, I; Pirker, KF; Jakopitsch, C; Sundermann, A; Oostenbrink, C; Furtmuller, PG; Obinger, C
12th European Biological Inorganic Chemistry Conference EuroBIC 2014
(2014) Chlorite to chloride and O2 conversion: new lessons from structural and mechanistic investigations of chlorite dismutase
Autoren: Obinger, C., Hofbauer, S., Schaffner, I., Pirker, K. F., Mlynek, G.,Djinovic-Carugo, K., Battistuzzi, G., Furtmüller, P. G
12th European Biological Inorganic Chemistry Conference EuroBIC 2014
(2013) Understanding highly stable chlorite dismutase form nitrate-oxidizing bacterium Candidatus “Nitrospira defluvii”
Autoren: Hofbauer, S., Gruber, C., Pirker, K. F., Schaffner, I., Hagmüller, A., Gysel, K., Mlynek, G., Kostan, J., Bellei, M., Daims, H., Djinovic-Carugo, K. Battistuzzi, G., Furtmüller, P.G. and Obinger, C
International Conference on Bioinorganic Chemistry ICBIC-16 2013
(2013) Understanding Chlorite Dismutase from Candidatus Nitrospira defluvii
Autoren: Hofbauer, S; Gruber, C; Pirker, KF; Schaffner, I; Furtmuller, PG; Obinger, C; Hagmuller, A; Gysel, K; Mlynek, G; Kostan, J; Djinovic-Carugo, K; Bellei, M; Battistuzzi, G; Daims, H
International Conference on Bioinorganic Chemistry ICBIC-16 2013
(2013) Spectroscopic Characterization of wild-type Chlorite Dismutase from Candidatus “Nitrospira defluvii” and selected variants
Autoren: Hofbauer, S., Flego, N., Schaffner, I., Pirker, K. F., Furtmüller, P. G., Howes, B. D., Obinger, C., Smulevich, G.
15th European Conference on the Spectroscopy of Biological Molecules
Mechanism of inhibition of chlorite dismutase
Autoren: Hofbauer, S., Schaffner, I., Gruber, C., Pirker, K.F., Jakopitsch, C., Sündermann, A., Oostenbrink, C., Furtmüller, P.G., Obinger, C.
Redox properties of the Fe3+/Fe2+ couple in wild-type and mutated heme chlorite dismutases
Autoren: Hofbauer, S., Bellei, M., Schaffner, I., Furtmüller, P.G., Obinger, C., Battistuzzi, C.
Construction of a molecular ON-switch for controlling CAR T cells with an orally available small molecule
Autoren: Brey, CU; Dobersberger, M; Schaffner, I; Mlynek, G; Pühringer, D; Salzer, B; Djinović-Carugo. K; Obinger, C; Holter, W; Lehner, M; Traxlmayr, MW
Biochemical and biophysical characterization of a new functional chlorite dismutase
Autoren: Schaffner, I., Hofbauer, S., Pirker, K.F., Furtmüller, P.G., Obinger, C.