Stefan Hofbauer

Presentations

• Year: 2024 -  Understanding molecular enzymology of porphyrin-binding dimeric α + β barrel proteins

  Autoren: Hofbauer, S

  Event: Minisymposium on Peroxygenase Discovery, Engineering, Production and Application 2024

• Year: 2023 -  Molecular mechanisms of prokaryotic heme biosynthesis enzymes

  Autoren: Hofbauer, S; Patil, G; Gabler, T; Falb, N; Furtmüller PG

  Event: UMHM - Unraveling Mysteries of Heme Metabolism

• Year: 2022 -  Biochemistry of Enzymes Involved in the Coproporphyrin-Dependent Heme Biosynthesis Pathway of Gram-Positive Bacteria

  Autoren: Hofbauer, S; Gabler, T; Patil, G; Michlits, H; Pfanzagl, V; Obinger, C; Furtmüller, PG

  Event: Gordon Research Conference - Chemistry and Biology of Tetrapyrroles

• Year: 2022 -  Spectroscopic characterization of the coproporphyrin III coproporphyrin ferrochelatase complex of Listeria monocytogenes

  Autoren: Dali, A; Sebastiani, S; Gabler, T; Obinger, C; Furtmüller, PG; Becucci, M; Hofbauer, S; Smulevich, G

  Event: OxiZymes 2022

• Year: 2022 -  Reactivity of peroxidases and chlorite dismutases with chlorite and hypochlorite: a spectroscopic investigation of short-lived intermediates trapped by fast freeze-quenching

  Autoren: Serra, I; Schmidt, D; Hofbauer, S; Pfanzagl, V; García-Rubio, I; Furtmüller, PG; Obinger C; and Van Doorslaer, V;

  Event: The 55th Annual International Meeting of the ESR Spectroscopy Group of the Royal Society of Chemistry 2022

• Year: 2022 -  Molecular mechanism of the last step of the heme b biosynthesis in Gram-positive bacteria: the rotation matters

  Autoren: Sebastiani, F; Michlits, H; Dali, A; Becucci, M; Hofbauer, S; Smulevich, G

  Event: 12th International Conference on Porphyrins and Phtalocyanines ICPP-12 2022

• Year: 2022 -  X-ray induced reduction of heme metal centers is protein-independent

  Autoren: Pfanzagl, V; Beale, JH; Michlits, H; Schmidt, D; Gabler, T; Obinger, C; Djinovic-Carugo, K; Hofbauer, S;

  Event: 33rd European Crystallographic Meeting

• Year: 2022 -  Structural and mechanistic insights in dimeric chlorite dismutase - Impact of pH and the dynamics of the catalytic arginine

  Autoren: Schmidt, D; Serra, I; Hofbauer, S; Pfanzagl, V; Van Doorslaer, S; Obinger, C; Furtmüller, P.G.

  Event: 16th European Biological Inorganic Chemistry 2022

• Year: 2022 -  Importance of H-bonds on substrate specificity and complex stability of firmicute coproporphyrin ferrochelatase

  Autoren: Gabler, T; Dali, A; Sebastiani, S; Helm, J; Obinger, C; Furtmüller, PG; Smulevich, G; Hofbauer, S

  Event: OxiZymes 2022

• Year: 2021 -  Coproporphyrin ferrochelatase – study of relevant residues for substrate and product binding

  Autoren: Gabler, T; Pfanzagl, V; Obinger, C; Furtmüller PG; Hofbauer, S

  Event: International Conference on Porphyrins and Phthalocyanines - ICPP11

• Year: 2019 -  Interaction of hydrogen sulfide with myeloperoxidase in presence of hydrogen peroxide or oxygen

  Autoren: Furtmüller, PG; Palinkas, Z; Garai, D; Rios-Gonzalez, BB; Lopez-Garriga, J; Hofbauer, S; Obinger, C; Nagy, P

  Event: 11th Human Peroxidase Meeting

• Year: 2019 -  Resonance Raman to understand the heme cavity impact on the structure and function of coproheme decarboxylase (ChdC) from Listeria monocytogenes

  Autoren: Milazzo, L; Hofbauer, S; Gabler, T; Furtmüller, PG; Obinger, C; Smulevich, G

  Event: 10th International Conference on Advanced Vibrational Spectroscopy

• Year: 2019 -  Posttranslational Modification of Heme in Peroxidases - Impact on Structure and Function

  Autoren: Furtmüller, PG; Nicolussi, A; Sevcnikar, B; Paumann-Page, M; Auer, M; Zamocky, M; Pfanzagl, V; Hofbauer, S; Obinger, C

  Event: 19th International Conference on Biological Inorganic Chemistry 2019

• Year: 2019 -  YfeX - A new player involved in the redox gated potassium efflux pump KefC

  Autoren: Pfanzagl, V; Schwaiger, L; Michlits, H; Hofbauer, S; Obinger, C

  Event: Gordon Research Conference: Mechanisms of Membrane Transport

• Year: 2019 -  Role of H98Y variant of human myoglobin in Myoglobinopathy

  Autoren: Hofbauer, S; Bernini, C; Pignataro, M; Obinger, C; Battistuzzi, G; Furtmüller, PG

  Event: 11th Human Peroxidase Meeting

• Year: 2019 -  An actinobacterial representative sheds a new light on the reaction mechanism of coproheme decarboxylases

  Autoren: Michlits, H; Pfanzagl, V; Furtmüller, PG; Djinovic-Carugo, K; Obinger, C; Hofbauer, S

  Event: 19th International Conference on Biological Inorganic Chemistry 2019

• Year: 2019 -  Molecular mechanism of coproheme to heme b conversion

  Autoren: Hofbauer, S; Milazzo, L; Gabler, T; Pühringer, D; Pfanzagl, V; Djinovic-Carugo, K; Furtmüller, PG; Obinger, C; Smulevich, G

  Event: 19th International Conference on Biological Inorganic Chemistry 2019

• Year: 2019 -  Molecular Mechanism of Enzymatic Chlorite Degradation

  Autoren: Obinger, C; Schaffner, I; Schmidt, D; Smulevich, G; Coates, L; Battistuzzi, G; Furtmüller, PG; Hofbauer, S

  Event: 19th International Conference on Biological Inorganic Chemistry 2019

• Year: 2019 -  X-ray induced redcution kinetics of heme metal centers is protein-independent - implications for structural studies of redox sensitive proteins

  Autoren: Pfanzagl, V; Beale, J; Schmidt, D; Michlits, H; Gabler, T; Djinovic-Carugo, K; Obinger, C; Hofbauer, S

  Event: 19th International Conference on Biological Inorganic Chemistry 2019

• Year: 2019 -  X-ray induced reduction of heme metal centers is protein-independent – implications for structural studies of redox sensitive proteins

  Autoren: Pfanzagl, V; Beale, JH; Schmidt, D; Michlits, H; Gabler, T; Djinovic-Carugo, C; Obinger, C; Hofbauer, S

  Event: Hot Topics in Crystallography 4

• Year: 2019 -  X-ray induced redcution kinetics of heme metal centers is protein-independent

  Autoren: Pfanzagl, V; Beale, J; Schmidt, D; Michlits, H; Gabler, T; Djinovic-Carugo, K; Obinger, C; Hofbauer, S

  Event: 11th Human Peroxidase Meeting

• Year: 2019 -  Manipulation of heme environment in the active site of chlorite dismutases and its impact on the enzymatic activity

  Autoren: Schmidt, D; Schaffner, I; Hofbauer, S; Furtmüller PG; Obinger, C

  Event: 19th International Conference on Biological Inorganic Chemistry 2019

• Year: 2019 -  Posttranslational modification of heme - Impact on generation of hypohalous acids

  Autoren: Obinger, C; Nicolussi, A; Auer, M; Sevcnikar, B; Paumann-Page, M; Hofbauer, S; Furtmüller, PG;

  Event: 11th Human Peroxidase Meeting

• Year: 2018 -  Coproheme decarboxylase from Listeria monocytogenes: insight into the active site structure

  Autoren: Milazzo, L; Hofbauer, S; Howes, BD; Gabler, T; Furtmüller, PG; Obinger, C; Smulevich, G.

  Event: Tenth International Conference on Porphyrins and Phthalocyanines (ICPP-10)

• Year: 2018 -  Characterization and comparison of the distal heme environment of dimeric and pentameric chlorite dismutases

  Autoren: Schmidt, D., Schaffner, I., Hofbauer, S., Mlynek, G., Djinović-Carugo, K., Furtmüller, P. G., Obinger, C.

  Event: OxiZymes 2018

• Year: 2018 -  Mechanistic Studies on Coproheme Decarboxylase

  Autoren: Hofbauer, S; Milazzo, L; Mlynek, G; Gabler, T; Howes, BD; Pfanzagl, V; Djinović-Carugo, K; Furtmüller, PG; Smulevich, G; Obinger, C

  Event: Tenth International Conference on Porphyrins and Phthalocyanines (ICPP-10)

• Year: 2018 -  Crystal and Electronic Structure of Compound I in Dye-decolorizing Peroxidases

  Autoren: Pfanzagl, V; Hofbauer, S; Beale, J; Mlynek, G; Michlits, H; Nys, K; Van Doorslaer, S; Djinovic-Carugo, K; Furtmüller, PG; Obinger, C

  Event: Tenth International Conference on Porphyrins and Phthalocyanines (ICPP-10)

• Year: 2018 -  Kinetic and spectroscopic characterization of EfeB

  Autoren: Michlits, H., Pfanzagl, V., Schwaiger, L., Furtmüller, P. G., Hofbauer, S., Obinger, C.

  Event: OxiZymes 2018

• Year: 2018 -  On Compound I formation in B-type dye decolorizing peroxidases - lessons from structural and kinetic studies.

  Autoren: Pfanzagl, V., Nys, K., Mlynek, G., Djinović-Carugo, K., Van Doorslaer, S., Furtmüller, P. G., Hofbauer, S., Obinger, C.

  Event: OxiZymes 2018

• Year: 2018 -  Molecular mechanism of enzymatic chlorite degradation

  Autoren: Obinger, C; Schaffner, I; Smulevich, G; Coates, L; Battistuzzi, G; Furtmüller, P.G; Hofbauer, S;

  Event: Tenth International Conference on Porphyrins and Phthalocyanines (ICPP-10)

• Year: 2018 -  Coproheme decarboxylases – phylogenetic prediction versus biochemical analysis.

  Autoren: Pfanzagl, V., Holcik, L., Maresch, D., Michlits, H., Furtmüller, P. G., Obinger, C., Hofbauer, S.

  Event: OxiZymes 2018

• Year: 2018 -  Posttranslational Modification of Heme in Peroxidases – Impact on Structure and Catalysis

  Autoren: Furtmüller, PG; Nicolussi, A; Auer, M; Paumann-Page, M; Sevcnikar, B; Pfanzagl, V; Zámocký, M; Hofbauer, S; Obinger, C;

  Event: Tenth International Conference on Porphyrins and Phthalocyanines (ICPP-10)

• Year: 2018 -  Coproheme Listeria monocytogenes HemQ and selected mutants to highlight the structure function

  Autoren: Milazzo, L; Hofbauer, S; Howes, BD; Obinger, C; Smulevich, G

  Event: Tenth International Conference on Porphyrins and Phthalocyanines (ICPP-10)

• Year: 2017 -  How heme to protein bonds modulate reactivity - Lessons from a bacterial peroxidase with homology to lactoperoxidase

  Autoren: Furtmüller, P.G; Nicolussi, A; Auer, M; Hofbauer, S; Bellei, M; Battistuzzi, G; and Obinger, C

  Event: 10th International Human Peroxidase Meeting - Breckenridge 2017

• Year: 2017 -  Roles of the distal Asp-Arg pair in compound I formation of K. pneumoniae dye-decolorizing peroxidase

  Autoren: Pfanzagl, V; Hofbauer, S; Nys, K; Djinović-Carugo, K; Battistuzzi, G; Van Doorslaer, S; Furtmüller, P.G; and Obinger, C;

  Event: International Conference on Bioinorganic Chemistry ICBIC-18 2017

• Year: 2017 -  Pre-steady-state kinetics reveal the substrate specifity and mechanism of halide oxidation of turncated human peroxidasin

  Autoren: Paumann-Page, M; Katz, R.-S; Bellei, M; Schwartz, I; Edenhofer, E; Sevcnikar, B; Soudi, M; Hofbauer, S; Battistuzzi, G; Furtmüller, P.G; and Obinger, C;

  Event: 10th International Human Peroxidase Meeting - Breckenridge 2017

• Year: 2017 -  Roles of the distal Asp-Arg pair in Compound I formation of K. pneumoniae dye-decolorizing peroxidase

  Autoren: Pfanzagl, V; Hofbauer, S; Nys, K; Djinovic-Carugo, K; Battistuzzi, G; Van Doorslaer, S; Furtmuller, PG; Obinger, C

  Event: International Conference on Bioinorganic Chemistry ICBIC-18 2017

• Year: 2016 -  High-resultion X-ray and neutron diffration structures and biophysical studies on a novel dimeric chlorite dismutase

  Autoren: Schaffner, I., Mlynek, G., Hofbauer, S., Smulevich, G., Battistuzzi, G., Djinovic-Carugo, K., Furtmüller, P. G., Coates, L., Obinger, C.

  Event: 79th Harden Conference on Oxygen Evolution and Reduction - Common Principles

• Year: 2016 -  Chlorite dismutase: Combining X-ray/neutron crystallography to investigate structure-function relationships

  Autoren: Schaffner, I; Mlynek, G; Coates, L; Hofbauer, S; Djinović-Carugo, K; Furtmüller, P.G; Obinger, C

  Event: OxiZymes 2016

• Year: 2016 -  Chlorite dismutase: distal heme environment and its role in irreversible enzyme inactivation

  Autoren: Schaffner, I., Hofbauer, S., Mlynek, G., Battistuzzi, G., Djinovic-Carugo, K., Furtmüller, P. G., Obinger, C.

  Event: 13th European Biological Inorganic Chemistry Conference EuroBIC 2016

• Year: 2016 -  Dye decolorizing peroxidases - A new heme-peroxidase family with ancient roots

  Autoren: Pfanzagl, V; Schaffner, I; Hofbauer, S; Furtmuller, P; Obinger, C

  Event: European Congress on Biotechnology 2016

• Year: 2016 -  Dioxygen evolution by chlorite dismutase depends on co-ordination of transiently produced hypochlorite to an oxoiron(IV) intermediate

  Autoren: Hofbauer, S., Grünwald-Gruber, C., Schaffner, I., Sündermann, A., Jakopitsch, C., Oostenbrink, C., Djinovic-Carugo, K., Furtmüller, P.G., Obinger, C.

  Event: 79th Harden Conference on Oxygen Evolution and Reduction

• Year: 2016 -  Dye decolorizing peroxidases – a new heme-peroxidase family with ancient roots

  Autoren: Pfanzagl, V; Schaffner, I; Hofbauer, S; Furtmüller, P.G; Obinger, C

  Event: 17th European Congress on Biotechnology ECB17 2016

• Year: 2016 -  Coproheme and HemQ

  Autoren: Hofbauer, S., Scheiblbrandner, S., Schaffner, I., Djinović-Carugo, K., Battistuzzi, G., Furtmüller, P. G., Obinger, C.

  Event: 13th European Biological Inorganic Chemistry Conference EuroBIC 2016

• Year: 2014 -  Mechanistic studies on a new functional dimeric chlorite dismutase

  Autoren: Schaffner, I; Flego, N; Mlynek, G; Bellei, M; Hofbauer, S; Battistuzzi, G; Djinovic-Carugo, K; Smulevich, G; Furtmuller, PG; Obinger, C

  Event: 12th European Biological Inorganic Chemistry Conference EuroBIC 2014

• Year: 2014 -  Mechanism of reaction of chlorite with mammalian peroxidases

  Autoren: Jakopitsch, C; Pirker, KF; Flemmig, J; Hofbauer, S; Schlorke, D; Furtmuller, PG; Arnhold, J; Obinger, C

  Event: 12th European Biological Inorganic Chemistry Conference EuroBIC 2014

• Year: 2014 -  Chlorite inactivates mammalian peroxidases

  Autoren: Jakopitsch, C., Pirker, K.F., Flemmig, J. Hofbauer, S., Furtmüller, P.G., Schlorke, D., Arnhold, J., Obinger, C.

  Event: OxiZymes 2014

• Year: 2014 -  Biochemical and biophysical characterization of a new functional chlorite dismutase

  Autoren: Schaffner, I., Hofbauer, S., Pirker, K.F., Furtmüller, P.G., Obinger, C.

  Event: OxiZymes 2014

• Year: 2014 -  Understanding the inhibition mechanism of chlorite dismutase from the nitrite-oxidizing bacterium Candidatus Nitrospira defluvii

  Autoren: Hofbauer, S; Gruber, C; Schaffner, I; Pirker, KF; Jakopitsch, C; Sundermann, A; Oostenbrink, C; Furtmuller, PG; Obinger, C

  Event: 12th European Biological Inorganic Chemistry Conference EuroBIC 2014

• Year: 2014 -  Chlorite to chloride and O2 conversion: new lessons from structural and mechanistic investigations of chlorite dismutase

  Autoren: Obinger, C., Hofbauer, S., Schaffner, I., Pirker, K. F., Mlynek, G.,Djinovic-Carugo, K., Battistuzzi, G., Furtmüller, P. G

  Event: 12th European Biological Inorganic Chemistry Conference EuroBIC 2014

• Year: 2014 -  Redox properties of the Fe3+/Fe2+ couple in wild-type and mutated heme chlorite dismutases

  Autoren: Hofbauer, S., Bellei, M., Schaffner, I., Furtmüller, P.G., Obinger, C., Battistuzzi, C.

  Event: OxiZymes 2014

• Year: 2014 -  Characterization of the Major Peptidoglycan Hydrolase of Lactobacillus buchneri

  Autoren: Anzengruber, J; Courtin, P; Pabst, M; Neumann, L; Claes IJJ; Debreczeny, M; Hofbauer, S; Obinger, C; Altmann, F; Chapot-Chartier, M-P; Vanderleyden, J; Messner, P; Schäffer, C

  Event: FASEB Science Research Conference on Microbial Glycobiology

• Year: 2014 -  Chlorite dismutases and dye-decolorizing peroxidases – similarities and differences within a structural superfamily of heme proteins

  Autoren: Schaffner, I., Hofbauer, S., Furtmueller, P. G., Obinger, C.

  Event: 16th European Congress on Biotechnology 2014

• Year: 2014 -  Mechanism of inhibition of chlorite dismutase

  Autoren: Hofbauer, S., Schaffner, I., Gruber, C., Pirker, K.F., Jakopitsch, C., Sündermann, A., Oostenbrink, C., Furtmüller, P.G., Obinger, C.

  Event: OxiZymes 2014

• Year: 2013 -  New highly stable chlorinating bacterial peroxidase with autocatalytically formed covalent heme to protein bonds

  Autoren: Furtmuller, PG; Auer, M; Gruber, C; Pirker, K; Krioss, D; Hofbauer, S; Soudi, M; Obinger, C; Zamocky, M; Bellei, M; Battistuzzi, G

  Event: International Conference on Bioinorganic Chemistry ICBIC-16 2013

• Year: 2013 -  Understanding Chlorite Dismutase from Candidatus Nitrospira defluvii

  Autoren: Hofbauer, S; Gruber, C; Pirker, KF; Schaffner, I; Furtmuller, PG; Obinger, C; Hagmuller, A; Gysel, K; Mlynek, G; Kostan, J; Djinovic-Carugo, K; Bellei, M; Battistuzzi, G; Daims, H

  Event: International Conference on Bioinorganic Chemistry ICBIC-16 2013

• Year: 2013 -  Spectroelectrochemical characterization of heme enzymes

  Autoren: Bellei, M., Hofbauer, S., Furtmüller, P. G., Obinger, C., Battistuzzi, G.

  Event: International workshop on protein electron transfer: from fundamentals to applications for health

• Year: 2013 -  Understanding highly stable chlorite dismutase form nitrate-oxidizing bacterium Candidatus “Nitrospira defluvii”

  Autoren: Hofbauer, S., Gruber, C., Pirker, K. F., Schaffner, I., Hagmüller, A., Gysel, K., Mlynek, G., Kostan, J., Bellei, M., Daims, H., Djinovic-Carugo, K. Battistuzzi, G., Furtmüller, P.G. and Obinger, C

  Event: International Conference on Bioinorganic Chemistry ICBIC-16 2013

• Year: 2013 -  Spectroscopic Characterization of wild-type Chlorite Dismutase from Candidatus “Nitrospira defluvii” and selected variants

  Autoren: Hofbauer, S., Flego, N., Schaffner, I., Pirker, K. F., Furtmüller, P. G., Howes, B. D., Obinger, C., Smulevich, G.

  Event: 15th European Conference on the Spectroscopy of Biological Molecules

• Year: 2012 -  Redox theromdynamics of diverse chlorite dismutases

  Autoren: Hofbauer, S. Bellei, M. Sündermann, A. Kostan, J. Daims, H. Djinović-Carugo, K. Oostenbrink, C. Furtmüller, P.G. Battistuzzi, G. & Obinger, C.

  Event: OxiZymes 2012

• Year: 2012 -  Thermal and Conformational Stability of Pentameric Chlorite Dismutase from Candidatus Nitrospira defluvii

  Autoren: Hofbauer, S., Gysel, K., Mlynek, G., Kostan, J., Daims, H., Furtmüller, P.G., Djinovics-Carugo, K. and Obinger,C.

  Event: 9th International Conference on Protein Stability 2012 - From molecular level to market applications