Brigitte Gasser

Presentations

• Year: 2023 -  Uncovering near-zero growth associated long non-coding RNAs in Komagatella phaffii

  Autoren: Coltman, B; Rebnegger, C; Gasser, B

  Event: 11th Recombinant Protein Production 2023

• Year: 2023 -  Uncovering near-zero growth associated long non-coding RNAs in Komagatella phaffii

  Autoren: Coltman, B; Rebnegger, C; Gasser, B

  Event: ICYGMB31 - YEAST 2023

• Year: 2023 -  Towards near-zero growth production ? Implications for strain and bioprocess design

  Autoren: Gasser, B

  Event: CDG Forum

• Year: 2023 -  In vivo monitoring of reactive oxygen species in the yeast Komagataella phaffii using a genetically encoded fluorescent H2O2 biosensor

  Autoren: Honorato, VM; Molin, M; Gasser, B

  Event: YEAST 2023

• Year: 2023 -  Increasing global translation activity and its impact on Komagataella phaffii

  Autoren: Staudacher, J; Rebnegger, C; Mattanovich, D; Gasser B

  Event: YEAST 2023

• Year: 2023 -  Protein production dynamics and physiological adaptation of recombinant Komagataella phaffii at near-zero growth rates

  Autoren: Rebnegger, C; Kowarz, V; Coltman, B; Mattanovich, D; Gasser, B

  Event: PYFF 8

• Year: 2023 -  Characterising an orthogonal thiamine-responsive riboswitch for expression control in the yeast Komagataella phaffii

  Autoren: Malecki, P; Rebnegger, C; Gasser B

  Event: YEAST 2023

• Year: 2023 -  Pushing and pulling proteins into the yeast secretory pathway enhances recombinant protein secretion

  Autoren: Zahrl, RJ; Prielhofer, R; Ata, Ö; Baumann, K; Burgard, J; Mattanovich, D; Gasser B

  Event: YEAST 2023, ICYGMB31

• Year: 2023 -  Characterising an orthogonal thiamine-responsive riboswitch for expression control in the yeast Komagataella phaffii

  Autoren: Malecki, P; Rebnegger, C; Gasser, B

  Event: PYFF 8

• Year: 2023 -  Improving Lonza’s XS® Pichia production platform by systemic engineering

  Autoren: Adelanto, N; Staudacher, J; Rebnegger, C; Kiziak, Ch; Chang, Y; Gasser, B; Mattanovich, D

  Event: 11th Conference on Recombinant Protein Production 2023

• Year: 2023 -  Going beyond the limit: impact of increasing global translation activity on the productivity of recombinant secreted proteins in Pichia pastoris

  Autoren: Staudacher, J; Rebnegger, C; Mattanovich, D; Gasser, B

  Event: 11th Conference on Recombinant Protein Production 2023

• Year: 2023 -  Going beyond the limit: tuning global transcription and translation activity increases recombinant protein secretion in Komagataella phaffii

  Autoren: Gasser, B; Staudacher, J; Rebnegger, C; Mattanovich, D

  Event: PYFF 8

• Year: 2023 -  Cell engineering and stress: Impact of increasing global translation activity on the Pichia pastoris transcriptome and proteome

  Autoren: Staudacher, J; Rebnegger, C; Mattanovich, D; Gasser, B

  Event: Microbial Stress 2023

• Year: 2023 -  Gasser, B

  Autoren: Pushing and pulling proteins into the yeast secretory pathway enhances recombinant protein secretion

  Event: YEAST 2023

• Year: 2022 -  Maintenance energy requirements determine metabolic rewiring of Komagataella phaffii at glucose-limited near-zero growth conditions

  Autoren: Coltman, B; Rebnegger, C; Gasser, B; Zanghellini, J

  Event: 14th Annual Meeting ÖGMBT 2022 - Life Sciences - now more than ever

• Year: 2022 -  Unfolded protein response biosensors for recombinant protein expression

  Autoren: Godon, H; Puricellici, M; De, S; Adelantado, N; Kiziak, C; Gasser, B; Mattanovich, D

  Event: 2nd Microbial Engineering ECI 2022

• Year: 2022 -  Going beyond the limit: impact of increasing global translation activity on the productivity of recombinant secreted proteins in Pichia pastoris

  Autoren: Staudacher, J; Rebnegger, C; Mattanovich, D; Gasser, B

  Event: 2nd Microbial Engineering ECI 2022

• Year: 2022 -  Pichia production platform engineering by systemic changes

  Autoren: Kiziak, C; Adelantado, N; Staudacher, J; Rebnegger, C; Gasser, B; Mattanovich, D

  Event: 2nd Microbial Engineering ECI 2022

• Year: 2022 -  Maintenance energy requirements determine metabolic rewiring of Komagataella phaffii at glucose-limited near-zero growth conditions

  Autoren: Coltman, B; Rebnegger, C; Gasser, B; Zanghellini, J

  Event: 36th International Specialised Symposium on Yeasts ISSY 2022

• Year: 2022 -  Flo8 – A versatile regulator for improving recombinant protein production in Pichia pastoris

  Autoren: Rebnegger, C; Kowarz, V; Flores, M; Mattanovich, D; Gasser, B

  Event: 2nd Microbial Engineering ECI 2022

• Year: 2022 -  Boosting transformation efficiency of Pichia pastoris

  Autoren: Hussein, M; Mattanovich, D; Gasser, B

  Event: European Summit of Industrial Biotechnology ESIB & Pichia & 11th International Conference on Fiber & Polymer Biotechnology IFPB 2022

• Year: 2022 -  In pursuit of an orthogonal molecular switch for Komagataella phaffii

  Autoren: Malecki, P; Rebnegger, C; Gasser, B

  Event: 6th Applied Synthetic Biology in Europe ASBE 2022

• Year: 2022 -  Impact of oxygen availability on organelle-specific redox potentials and stress in recombinant protein producing Pichia pastoris

  Autoren: Kostopoulou, A; Rebnegger, C; Gasser, B; Mattanovich, D

  Event: 2nd Microbial Engineering ECI 2022

• Year: 2022 -  Investigating the role of oxidative stress response genes in protein secretion using a novel combinatorial Golden Gate based approach

  Autoren: Mendes Honorato, V; Staudacher, J; Prielhofer, R; Gasser, B

  Event: 2nd Microbial Engineering ECI 2022

• Year: 2022 -  Going beyond the limit: Increasing global translation activity leads to increased productivity of recombinant secreted proteins in Pichia pastoris

  Autoren: Staudacher, J; Rebnegger, C; Mattanovich, D; Gasser, B

  Event: European Summit of Industrial Biotechnology ESIB & Pichia & 11th International Conference on Fiber & Polymer Biotechnology IFPB 2022

• Year: 2022 -  Flo8 – A versatile regulator for improving recombinant protein production in Pichia pastoris

  Autoren: Rebnegger, C; Kowarz, V; Flores, M; Mattanovich, D; Gasser, B

  Event: European Summit of Industrial Biotechnology ESIB & Pichia & 11th International Conference on Fiber & Polymer Biotechnology IFPB 2022

• Year: 2022 -  In pursuit of an orthogonal molecular switch for Komagataella phaffii

  Autoren: Małecki, P; Rebnegger, C; Gasser; B

  Event: 14th Annual Meeting ÖGMBT 2022 - Life Sciences - now more than ever

• Year: 2022 -  Maintenance energy requirements determine metabolic rewiring of Komagataella phaffii at glucose-limited near-zero growth conditions

  Autoren: Coltman, B; Rebnegger, C, Zanghellini, J, Gasser, B

  Event: European Summit of Industrial Biotechnology ESIB & Pichia & 11th International Conference on Fiber & Polymer Biotechnology IFPB 2022

• Year: 2022 -  Going beyond the limit: tuning global transcription and translation activity increases recombinant protein secretion in Pichia pastoris

  Autoren: Gasser, B

  Event: BPI Europe 2019

• Year: 2022 -  Dynamic mathematical modelling of fed-batch cultivation to maximize recombinant protein production by Komagataella phaffii

  Autoren: John Muthuraj, SMP; Gasser, B

  Event: European Summit of Industrial Biotechnology ESIB & Pichia & 11th International Conference on Fiber & Polymer Biotechnology IFPB 2022

• Year: 2022 -  Super-fast oxidases and more: novel yeast enzymes and mechanisms of oxidative protein folding

  Autoren: Palma, A; Ruddock, L; Gasser, B

  Event: European Summit of Industrial Biotechnology ESIB & Pichia & 11th International Conference on Fiber & Polymer Biotechnology IFPB 2022

• Year: 2022 -  In pursuit of an orthogonal molecular switch for Komagataella phfaffii

  Autoren: Malecki, P; Rebnegger, C; Gasser, B

  Event: 14th Annual Meeting ÖGMBT 2022 - Life Sciences - now more than ever

• Year: 2022 -  Unfolded protein response biosensors for recombinant protein production

  Autoren: Godon, H; Puricelli, M; De, S; Adelantado, N; Kiziak, C; Gasser, B; Mattanovich, D

  Event: 14th Annual Meeting ÖGMBT 2022 - Life Sciences - now more than ever

• Year: 2022 -  Unfolded protein response biosensors for recombinant protein expression

  Autoren: Godon, H; Puricelli, S; De, S; Adalanto, C; Kiziak, C; Gasser, B; Mattanovich, D

  Event: European Summit of Industrial Biotechnology ESIB & Pichia & 11th International Conference on Fiber & Polymer Biotechnology IFPB 2022

• Year: 2022 -  Maintenance energy requirement largely determines metabolic rewiring of Komagataella phaffii at glucose limited near zero growth

  Autoren: Coltman, B; Rebnegger, C; Gasser, B; Zanghellini, J

  Event: 6th Applied Synthetic Biology in Europe ASBE 2022

• Year: 2022 -  Pichia production host engineering by systemic host changes

  Autoren: Kiziak, C; Adelanto, N; Staudacher, J; Rebnegger, C; Gassser, B; Mattanovich, D

  Event: European Summit of Industrial Biotechnology ESIB & Pichia & 11th International Conference on Fiber & Polymer Biotechnology IFPB 2022

• Year: 2022 -  Strategies to improve yeast-based production of antibody molecules

  Autoren: Gasser, B

  Event: 3R Online Seminar Series

• Year: 2022 -  Impact of oxygen availability on organelle-specific redox potentials and stress in recombinant protein producing Pichia pastoris

  Autoren: Kostopoulou, A; Rebnegger, C; Gasser, B; Mattanovich, D

  Event: European Summit of Industrial Biotechnology ESIB & Pichia & 11th International Conference on Fiber & Polymer Biotechnology IFPB 2022

• Year: 2022 -  Protein production dynamics and pyhsiological adaptation of recombinant Pichia pastoris at near-zero growth rates

  Autoren: Rebnegger, C; Kowarz, V; Coltman, B; Mattanovich, D; Gasser, B

  Event: European Summit of Industrial Biotechnology ESIB & Pichia & 11th International Conference on Fiber & Polymer Biotechnology IFPB 2022

• Year: 2022 -  Lebende Proteinfabriken: von der Zelle zum Produkt

  Autoren: Gasser, B

  Event: Töchtertag 2022

• Year: 2021 -  Redox balancing in recombinant protein-producing Pichia pastoris with altered protein folding

  Autoren: Palma, A; Ruddock, L; Mattanovich, D; Gasser, B

  Event: ICY15 meets ICYGMB30

• Year: 2021 -  Assessing flux rearrangements of an alternate methanol metabolism that enables efficient recombinant protein production in Pichia pastoris

  Autoren: Coltman, B; Zavec, D; Mattanovich, D; Gasser, B; Zanghellini, J

  Event: ICY15 meets ICYGMB30

• Year: 2021 -  Engineering the glucose responsive promoter PG1

  Autoren: Flores Villegas, MC; Rebnegger, C; Kowarz, V; Kiziak, C; Mattanovich, D; Gasser, B

  Event: ICY15 meets ICYGMB30

• Year: 2021 -  Investigating the role of oxidative stress response genes in protein secretion using a novel Golden PiCS-based approach.

  Autoren: Mendes Honorato, V; Staudacher, J; Gasser B.

  Event: Pichia 2021

• Year: 2021 -  Flo8 – a versatile regulator for improving recombinant protein production in Pichia pastoris

  Autoren: Rebnegger, C; Kowarz, V; Flores Villegas, M; Mattanovich, D; Gasser, B

  Event: ICY15 meets ICYGMB30

• Year: 2021 -  Preventing morphological cell heterogeneity in the yeast Pichia pastoris (syn Komagataella phaffii): involvement of the FLO gene family.

  Autoren: De, S; Rebnegger, C; Buchetics, M; Moser, J; Tatto, N; Graf, AB; Mattanovich, D; Gasser, B.

  Event: EFB 2021

• Year: 2021 -  Treatment with surfactants enables quantification of translational activity by O-propargyl-puromycin labelling in P. pastoris.

  Autoren: Staudacher, J; Rebnegger, C; Gasser, B

  Event: Pichia 2021 Conference

• Year: 2021 -  Treatment with surfactants enables quantification of translational activity by O-propargyl-puromycin labelling in P. pastoris.

  Autoren: Staudacher, J; Rebnegger, C; Gasser, B

  Event: 15th International Congress on Yeast / 30th Int. Conference on Yeast Genetics and Molecular Biology (ICY15 meets ICYGMB30)

• Year: 2021 -  Assessing flux rearrangements of an alternate methanol metabolism that enables efficient recombinant protein production in Pichia pastoris

  Autoren: Coltman, B; Zavec, D; Mattanovich, D; Gasser, B; Zanghellini, J

  Event: 7th Conference on Constraint-Based Reconstruction and Analysis COBRA 2021

• Year: 2021 -  Going beyond the limit: impact of increasing global translation activity on the productivity of recombinant secreted proteins in Pichia pastoris.

  Autoren: Staudacher, J; Rebnegger, C; Mattanovich, D; Gasser, B

  Event: 15th International Congress on Yeast / 30th Int. Conference on Yeast Genetics and Molecular Biology (ICY15 meets ICYGMB30)

• Year: 2021 -  Impact of cultivation conditions on organelle-specific redox potentials and stress in recombinant protein producing Pichia pastoris

  Autoren: Kostopoulou, A; Rebnegger, C; Gasser, B; Mattanovich, D

  Event: ICY15 meets ICYGMB30

• Year: 2021 -  A synthetic Calvin cycle enables autotrophic growth in Pichia pastoris

  Autoren: Gaßler, T; Baumschabl, M; Egermeier, M; Gasser, B; Sauer, M; Steiger, M; Mattanovich, D

  Event: ICY15 meets ICYGMB30

• Year: 2021 -  Investigating the role of oxidative stress response genes in protein secretion using a novel Golden PiCS-based approach

  Autoren: Mendes Honorato, V; Staudacher, J; Gasser B

  Event: ICY15 meets ICYGMB30

• Year: 2020 -  Redox balancing in recombinant protein-producing Pichia pastoris with altered protein folding

  Autoren: Palma, A; Zavec, D; Mattanovich, D; Gasser, B.

  Event: 5th Applied Synthetic Biology in Europe 2020

• Year: 2020 -  A synthetic Calvin cycle enables autotrophic growth in yeast

  Autoren: Gassler, T; Egermeier, M; Gasser, B; Sauer, M; Steiger, MG; Mattanovich, D

  Event: 5th Applied Synthetic Biology Conference in Europe 2020

• Year: 2019 -  Subcellular proteome atlas of the yeast Komagataella phaffii

  Autoren: Valli, M; Grillitsch, KH; Grünwald-Gruber, C; Tatto, NE; Hrobath, B; Klug, L; Ivashov, V; Hauzmayer, S; Koller, M; Leisch, F; Gasser, B; Graf AB; Altmann, F; Daum, G; Mattanovich D

  Event: PYFF7 2019

• Year: 2019 -  Slow growth rate triggered transition to pseudohyphal phenotype of the protein production host Pichia pastoris

  Autoren: De, S; Buchetics M; Rebnegger, C; Mattanovich, D; Gasser, B

  Event: RPP10 2019

• Year: 2019 -  XS™ Pichia 2.0: closing the gap between bacterial and mammalian systems for the production of recombinant proteins

  Autoren: Adelantado, N; Claes, K; Reichinger, M; Wagner, N; Prielhofer, R; Gasser, B; Mattanovich, D; Kiziak, Ch

  Event: RPP10 2019

• Year: 2019 -  Protein production dynamics and physiological adaptiation of recombinant Pichia pastoris at near-zero growth rates

  Autoren: Rebnegger, C; Kowarz, V; Mattanovich, D; Gasser, B

  Event: PYFF7 2019

• Year: 2019 -  A synthetic yeast for efficient assimilation of carbon dioxide

  Autoren: Gassler, T; Gasser, B; Sauer, M; Steiger, M; Mattanovich D

  Event: 47th Annual Conference on Yeasts 2019

• Year: 2019 -  Introduction of unnatural amino acids in recombinant proteins with the yeast Pichia pastoris

  Autoren: Tir, N;Heistinger, L; Gasser, B; Mattanovich, D

  Event: 26 HSKIKI - 26th Croatian Meeting of Chemists and Chemical Engineers

• Year: 2019 -  Metabolic response to model-based engineering of NADPH supply in Pichia pastoris

  Autoren: Peña, D; Haltrich, D; Mattanovich, D; Zanghellini J; Gasser, B

  Event: RPP10 2019

• Year: 2019 -  Introduction of unnatural amino acids in recombinant proteins with the yeast Pichia pastoris

  Autoren: Tir, N; Heistinger, L; Gasser, B; Mattanovich, D

  Event: RPP10 2019

• Year: 2019 -  A synthetic yeast for efficient assimilation of carbon dioxide

  Autoren: Gassler T; Gasser B; Sauer M; Steiger MG; Mattanovich D

  Event: 46th Annual Conference on Yeasts 2019

• Year: 2019 -  Slow Growth Rate triggered transition to a pseudohyphal lifestyle of the protein production host Pichia pastoris

  Autoren: De, S; Buchetics, M; Rebnegger, C; Mattanovich, D; Gasser, B

  Event: BME 2019

• Year: 2019 -  Population heterogenity of the Komagataella phaffii mating response

  Autoren: Heistinger, L; Gasser, B; Mattanovich, D

  Event: PYFF7 2019

• Year: 2019 -  Analysis of intracellular interaction partners of recombinant proteins in Pichia pastoris

  Autoren: Schmelzer, B; Grünwald-Gruber, C; Altmann, F; Gasser, B; Mattanovich, D

  Event: RPP10 2019

• Year: 2019 -  Towards establishing a method to measure translation in Pichia pastoris

  Autoren: Staudacher, J; Gasser, B

  Event: RPP10 2019

• Year: 2019 -  Synthetic biology for efficient assimilation of carbon dioxide

  Autoren: Gassler T; Gasser B; Sauer M; Steiger MG; Mattanovich D

  Event: 14th Asian Congress on Biotechnology ACB 2019

• Year: 2019 -  Characterization of O-glycans in recombinant proteins produced in Pichia pastoris

  Autoren: Radoman, B; Grünwald-Gruber, C; Gasser, B; Altmann, F; Mattanovich D;

  Event: RNA Editing Gordon Research Conference (GRC) 2019

• Year: 2019 -  Characterization of transcription factors in Pichia pastoris

  Autoren: Flores Villegas, M; Mattanovich, D; Gasser, B

  Event: RPP10 2019

• Year: 2019 -  Towards establishing a method to measure translation in Pichia pastoris

  Autoren: Staudacher, J; Gasser, B;

  Event: 29 Int. Conference on Yeast Genetics and Molecular Biology

• Year: 2018 -  A Synthetic Yeast for Efficient Assimilation of Carbon Dioxide.

  Autoren: Gaßler, Thomas; Gasser, Brigitte; Sauer, Michael; Matthias G. Steiger; Mattanovich, D

  Event: 12th Metabolic Engineering 2018

• Year: 2018 -  Engineering vacuolar sorting pathways for efficient secretion of recombinant proteins

  Autoren: Marsalek, L; Gruber, C; Altmann, F; Mattanovich, D; Puxbaum, V; Gasser, B;

  Event: Microbial Engineering

• Year: 2018 -  A synthetic yeast for efficient assimilation of carbon dioxide

  Autoren: Gassler T; Gasser B; Sauer M; Steiger M; Mattanovich D

  Event: Advances in Microbiology and Biotechnology 2018

• Year: 2018 -  Production under the AOX1 promoter in methanol utilization negative Pichia pastoris: an efficient expression system for less intensive fermentation

  Autoren: Zavec, D; Gasser, B; Mattanovich, D

  Event: ISSY34 2018

• Year: 2018 -  The Cat8 transcription factors regulate carbon source utilization in Pichia pastoris

  Autoren: Barbay, D; Mattanovich, D; Gasser, B

  Event: Non-conventional yeasts: from basic research to application 2018

• Year: 2018 -  Dissection of growth-rate- and cell-cycle-dependent gene regulation in Pichia pastoris

  Autoren: Rebnegger, C; Burgard, J; Graf, AB; Maurer, M; Gasser, B; Mattanovich, D;

  Event: ECB 2018

• Year: 2018 -  Industrial yeast strain efficiently assimilating carbon dioxide

  Autoren: Steiger, M; Gassler, T; Sauer, M; Gasser, B; Mattanovich, D

  Event: 10th Carbon Dioxide Utilisation Summit

• Year: 2018 -  Switching the metabolism of Pichia pastoris to efficiently assimilate CO2

  Autoren: Gaßler, T; Gasser, B; Sauer, M; Steiger, M; Mattanovich, D;

  Event: 10th ÖGMBT Annual Meeting & Biophysics Austria Annual Meeting 2018

• Year: 2018 -  Impact of puromycin on different Pichia pastoris strains

  Autoren: Staudacher, J: Gasser, B;

  Event: 10th ÖGMBT Annual Meeting & Biophysics Austria Annual Meeting 2018

• Year: 2018 -  Elucidation of the regulatory network of Trichoderma reesei operating under cellulose-degrading conditions

  Autoren: Radebner, T; Wanka, F; Gasser, B; Seiboth, B;

  Event: 14th European Conference on Fungal Genetics ECFG14 2018

• Year: 2018 -  Design and development of a comprehensive online resources for the biotechnological yeast Komagataellaphaffii

  Autoren: Tatto, N; Valli, M; Gasser, B; Graf, A; Mattanovich, D

  Event: German Conference on Bioinformatics 2018

• Year: 2018 -  Design of novel Pichia pastoris promoters with high performance in methanol-free fed batch

  Autoren: Gasser, B

  Event: 5th BioProScale Symposium 2018

• Year: 2018 -  A synthetic yeast for efficient assimilation of carbon dioxide

  Autoren: Gassler T; Gasser B; Sauer M; Steiger MG; Mattanovich D

  Event: Apllied Synthetic Biology in Europe 2018

• Year: 2018 -  Regulation of mating in the methylotrophic yeast Komagatella phaffii

  Autoren: Heistinger, L; Moser, J; Tatto, N.E; Valli, M; Gasser, B; Mattanovich, D

  Event: Non-conventional yeasts: from basic research to application 2018

• Year: 2018 -  Characterizing vacuolar protein sorting pathways for enhanced protein secretion in the yeast Pichia pastoris (Komagatella spp)

  Autoren: Marsalek, L; Puxbaum, V; Gruber-Grünwald, C; Altmann, F; Mattanovich, D; Gasser, B

  Event: Non-conventional yeasts: from basic research to application 2018

• Year: 2018 -  Regulation of pseudohyphal growth and flocculation in Pichia pastoris

  Autoren: De, S; Rebnegger, C; Moser, J; Tatto, N.E; Mattanovich, D; Gasser, B;

  Event: Non-conventional yeasts: from basic research to application 2018

• Year: 2018 -  Engineering transcription regulation in Pichia pastoris.

  Autoren: Flores Villegas, MC; Mattanovich, D; Gasser, B

  Event: Non-conventional yeasts: from basic research to application 2018

• Year: 2018 -  A synthetic yeast for efficient assimilation of carbon dioxid

  Autoren: Gaßler, T; Gasser, B; Sauer, M; Steiger MG; Mattanovich, D

  Event: 4th Applied Synthetic Biology in Europe 2018

• Year: 2018 -  Characterization of O-glycans in recombinant proteins produces in Pichia pastoris,

  Autoren: Radoman, B; Grünwald-Gruber, C; Schmelzer, B; Gasser, B; Mattanovich, D; Altmann, F

  Event: EMBO Practical Course - Characterization of post translational modifications in cellular signaling

• Year: 2018 -  Characterization of O-glycosylation in recombinant Pichia pastoris

  Autoren: Radoman, B; Grünwald-Gruber, C; Rebnegger, C; Schmelzer, B; Altmann, F; Mattanovich, D; Gasser, B

  Event: EMBO Workshop - Enzymes, biocatalysis ans chemical biology: The new frontiers

• Year: 2018 -  The Cat8 transcription factors regulate carbon source utilization in Pichia pastoris

  Autoren: Barbay, D; Mattanovich, D; Gasser, B

  Event: 10th ÖGMBT Annual Meeting & Biophysics Austria Annual Meeting 2018

• Year: 2018 -  Enlarging the synthetic biology toolbox for Pichia pastoris: Golden Gate cloning and CRISPR/Cas9

  Autoren: Gassler, T; Prielhofer, R; Heistinger, L; Zahrl, R; Zehetbauer, F; Steiger, MG; Sauer, M; Mattanovich, D; Gasser, B;

  Event: Microbial Engineering

• Year: 2017 -  Enlarging the synthetic biology toolbox for Pichia pastoris: Golden Gate cloning and CRISPR/Cas9

  Autoren: Gaßler, T; Prielhofer, R ; Heistinger, L; Zahrl, R; Zehetbauer, F; Steiger, M; Sauer, M; Gasser, B; Mattanovich, D;

  Event: Synthetic Biology Engineering Evolution Design SEED 2017

• Year: 2017 -  Role of epigenetic regulation in flocculation and pseido-hyphal growth of the protein production host Pichia pastoris

  Autoren: De, S; Rebnegger, C; Mattanovich, D; Gasser, B;

  Event: European Summit of Industrial Biotechnology ESIB 2017

• Year: 2017 -  Promoter and process engineering for recombinant protein production in Pichia pastoris towards simple, fast and methanol-free cultivation regimes and high product titers

  Autoren: Prielhofer, R; Reichinger, M; Wagner, N; Claes, K; Kiziak, C; Gasser, B; Mattanovich, D;

  Event: 9th International Conference on Recombinant Protein Production RPP9 2017

• Year: 2017 -  Shedding light on the regulatory network of the fungus Trichoderma reesei operating under cellulose-degrading conditions

  Autoren: Radebner, T; Wanka, F; Gasser, B; Seiboth, B;

  Event: 2nd Symposium on Plant Biomass Conversion by Fungi

• Year: 2017 -  Identification of intracellular interaction partners of recombinant proteins

  Autoren: Schmelzer, B; Grünwald-Gruber, C; Altmann, F; Gasser, B; Mattanovich, D;

  Event: 9th International Conference on Recombinant Protein Production RPP9 2017

• Year: 2017 -  Promoter and process engineering for recombinant protein production in Pichia pastoris towards simple, fast and methanol-free cultivation regimes and high product titers

  Autoren: Prielhofer, R; Reichinger, M; Wagner, N; Claes, K; Kiziak, Ch; Gasser, B; Mattanovich, D;

  Event: European Summit of Industrial Biotechnology ESIB 2017

• Year: 2017 -  Characterizing Vacuolar Protein Sorting Pathways in the Yeast Pichia Pastoris

  Autoren: Marsalek, L; Grünwald-Gruber, C; Altmann, F; Mattanovich, D; Puxbaum, V; Gasser, B;

  Event: European Summit of Industrial Biotechnology ESIB 2017

• Year: 2017 -  Characterizing vacuolar protein sorting pathways in the yeast Pichia pastoris

  Autoren: Gasser, B; Marsalek, L; Gruber, C; Altmann, F; Mattanovich, D; Puxbaum, V;

  Event: 28th International Conference on Yeast Genetics and Molecular Biology ICYGMB 2017

• Year: 2017 -  Characterization of transcriptional regulatory proteins in Pichia pastoris

  Autoren: Barbay, D; Mattanovich, D; Gasser, B;

  Event: 28th International Conference on Yeast Genetics and Molecular Biology ICYGMB 2017

• Year: 2017 -  Omics-data integration into the genome-scale metabolic model of Pichia pastoris enables estimation of protein production in capabilities

  Autoren: Pena-Navarro, D; Haltrich, D; Mattanovich, D; Gasser, B; Zanghellini, J;

  Event: 9th International Conference on Recombinant Protein Production RPP9 2017

• Year: 2017 -  Identification of intracellular interaction partners of recombinant proteins

  Autoren: Schmelzer, B; Grünwald-Gruber, C; Altmann, F; Gasser, B; Mattanovich, D;

  Event: European Summit of Industrial Biotechnology ESIB 2017

• Year: 2017 -  Synthetic biology toolbox and application for recombinant protein production in Pichia pastoris: Golden Gate cloning and CRISPR/Cas9.

  Autoren: Prielhofer, R; Barrero, J; Steuer, S; Zahrl, R; Baumann, K; Heistinger, L; Jarych, D; Mattanovich, D; Gasser, B;

  Event: 9th International Conference on Recombinant Protein Production RPP9 2017

• Year: 2017 -  An alternative approach to methanol driven protein production with Pichia pastoris

  Autoren: Zavec, D; Gasser, B; Mattanovich, D;

  Event: European Summit of Industrial Biotechnology ESIB 2017

• Year: 2017 -  Shedding light on the regulatory network of the fungus Trichoderma reesei operating under cellulose-degrading conditions

  Autoren: Radebner, T; Wanka, F; Gasser, B; Seiboth, B;

  Event: 12th conference of the VAAM special group Molecular Biology by Fungi

• Year: 2017 -  Characterization of O-glycans in recombinant proteins produced in Pichia pastoris

  Autoren: Radoman, B; Grünwald-Gruber, C; Schmelzer, B; Gasser, B; Altmann, F; Mattanovich, D;

  Event: European Summit of Industrial Biotechnology ESIB 2017

• Year: 2017 -  Shedding light on the regulatory network of the fungus Trichoderma reesei operating under cellulose-degrading conditions.

  Autoren: Radebner, T; Wanka, F; Gasser, B; Seiboth, B;

  Event: 2nd Symposium on Plant Biomass Conversion by Fungi

• Year: 2017 -  The regulatory network of Trichoderma reesei present under cellulase expressing conditions

  Autoren: Radebner, T; Wanka, F; Gasser, B; Seiboth, B;

  Event: European Summit of Industrial Biotechnology ESIB 2017

• Year: 2017 -  Engineering protein quality control mechanisms and vesicular sorting pathways for efficient secretion of recombinant proteins

  Autoren: Gasser, B;

  Event: Protein Engineering 2017

• Year: 2017 -  A binuclear mutant of Pichia pastoris was selected as an efficient recombinant protein producer

  Autoren: Buchetics, M; Baumann, K; Valli, M; Grillitsch, K; Daum, G; Zellnig, G; Mattanovich, D; Gasser, B;

  Event: 9th International Conference on Recombinant Protein Production RPP9 2017

• Year: 2017 -  Shedding light on the regulatory network of the fungus Trichoderma reesei operating under cellulose-degrading conditions.

  Autoren: Radebner, T; Wanka, F; Gasser, B; Seiboth, B;

  Event: 12th conference of the VAAM special group Molecular Biology by Fungi

• Year: 2017 -  RNA-Seq analysis protocol development for Komagataella phaffii

  Autoren: Tatto, N; Moser, J; Gasser, B; Mattanovich, D; Graf, A;

  Event: ISMB/ECCB 2017

• Year: 2017 -  Role of epigenetic regulation in flocculation and pseudo-hyphal growth of the protein production host Pichia pastoris

  Autoren: De, S; Rebnegger, C; Mattanovich, D; Gasser, B;

  Event: 9th International Conference on Recombinant Protein Production RPP9 2017

• Year: 2017 -  Characterization of O-glycans in recombinant proteins produced in Pichia pastoris

  Autoren: Radoman, B; Grünwald-Gruber, C; Schmelzer, B; Gasser, B; Altmann, F; Mattanovich, D;

  Event: 9th International Conference on Recombinant Protein Production RPP9 2017

• Year: 2017 -  Omics-data integration into the genome-scale metabolic model of Pichia pastoris enables estimation of protein production capabilities

  Autoren: Pena-Navarro, DA; Haltrich, D; Mattanovich, D; Gasser, B; Zanghellini, J;

  Event: European Summit of Industrial Biotechnology ESIB 2017

• Year: 2017 -  Characterization of transcriptional regulatory proteins in Pichia pastoris

  Autoren: Barbay, D; Mattanovich, D; Gasser, B;

  Event: European Summit of Industrial Biotechnology ESIB 2017

• Year: 2017 -  Enlarging the Synthetic Biology Toolbox for Pichia Pastoris: Golden Gate Cloning and CRISPR/Cas9

  Autoren: Gaßler, T; Prielhofer, R; Heistinger, L; Zahrl, R; Zehetbauer, F; Steiger, M; Sauer, M; Gasser, B; Mattanovich, D;

  Event: Synthetic Biology Engineering Evolution Design SEED 2017

• Year: 2017 -  Creation of Pichia pastoris strains with stable mating-types for the production of multimeric proteins

  Autoren: Heistinger, L; Gasser, B; Mattanovich, D;

  Event: 9th International Conference on Recombinant Protein Production RPP9 2017

• Year: 2017 -  Methanol utilization negative strains of Pichia pastroris for recombinant protein production

  Autoren: Zavec, Domen; Puxbaum, V; Gasser, B; Mattanovich, D;

  Event: 9th International Conference on Recombinant Protein Production RPP9 2017

• Year: 2017 -  RNASeq protocol development for K. phaffii

  Autoren: Tatto, N; Moser, J; Gasser, B; Mattanovich, D; Graf, A;

  Event: European Summit of Industrial Biotechnology ESIB 2017

• Year: 2017 -  The regulatory network of Trichoderma reesei under cellulase expressing conditions

  Autoren: Radebner, T; Wanka, F; Gasser, B; Seiboth, B;

  Event: European Summit of Industrial Biotechnology ESIB 2017

• Year: 2016 -  Curation of the Pichia pastoris (Komagatella phaffi) genome annotation by integration of RNA-Seq and proteomic data

  Autoren: Valli, M; Tatto, N; Peymann, A; Gruber, C; Landes, N; Ekker, H; Thallinger, G; Mattanovich, D; Gasser, B; Graf, A

  Event: ESIB 2016

• Year: 2016 -  Methanol metabolism revisited: The xylulose-monophosphate cycle of methanol assimilation utilizes a duplicated methanol inducible enzyme set and is entirely localized to peroxisomes

  Autoren: Rußmayer, H; Buchetics, M; Gruber, C; Valli, M; Grillitsch, K; Modarres, G; Drexler, H; Steiger, M; Daum, G; Graf, A; Altmann, F; Hann, S; Sauer, M; Mattanovich, D; Gasser, B;

  Event: Pichia 2016

• Year: 2016 -  On the relation of growth and protein secretion in budding yeasts

  Autoren: Rebnegger, C; Puxbaum, V; Buchetics, M; Gasser, B; Mattanovich, D;

  Event: 14th International Congress on Yeasts - ICY 2016

• Year: 2016 -  On the coupling of growth and protein secretion in budding yeasts

  Autoren: Rebnegger C; Puxbaum V; Buchetics M; Gasser B; Mattanovich D

  Event: 14th International Congress on Yeasts 2016

• Year: 2016 -  Matching the demand of protein production by metabolic engineering of the central metabolism: lessons learned from cofactor and amino acid metabolism in yeasts

  Autoren: Mattanovich, D; Russmayer, H; Nocon, J.; Hohlweg, J; Steiger, M; Sauer, M; Gasser, B;

  Event: 11th Metabolic Engineering 2016

• Year: 2016 -  Matching the demand of protein production by metabolic engineering of the central metabolism: lessons learned from cofactor and amino acid metabolism in yeasts

  Autoren: Russmayer H; Nocon J; Hohlweg J; Steiger MG; Sauer M; Gasser B; Mattanovich D

  Event: 11th Metabolic Engineering 2016

• Year: 2016 -  A winding road to the bud tip - exploring the secretion route of recombinant proteins in Pichia pastoris via live cell microscopy,

  Autoren: Puxbaum, V; Landes, N; Gasser, B; Mattanovich, D;

  Event: 14th International Congress on Yeasts - ICY 2016

• Year: 2016 -  Studying epigenetic regulation in fast and slow growing Pichia pastoris

  Autoren: De, S; Rebnegger, C; Mattanovich, D; Gasser, B

  Event: PYFF6 - 6th Conference on Physiology of Yeasts and Filamentous Fungi

• Year: 2016 -  Cellular mechanisms of regulation during enzyme production in Trichoderma reesei.

  Autoren: Radebner, T; Bischof, R; Gasser, B; Seiboth, B;

  Event: ESIB – European Summit of Industrial Biotechnology

• Year: 2016 -  Engineering protein quality control mechanisms and vesicular sorting pathways for efficient secretion of recombinant proteins

  Autoren: Gasser, B;

  Event: 14th International Congress on Yeasts - ICY 2016

• Year: 2016 -  The impact of ERAD on recombinant protein secretion in yeast

  Autoren: Zahrl, R; Pfeffer, M; Mattanovich, D; Gasser, B

  Event: 14th International Congress on Yeasts - ICY 2016

• Year: 2016 -  On the coupling of growth and protein secretion in budding yeasts

  Autoren: Rebnegger, C; Puxbaum, V; Buchetics, M; Gasser, B; Mattanovich, D;

  Event: Power of Microbes in Industry and Environment

• Year: 2016 -  Identification of intracellular interaction partners of recombinant proteins

  Autoren: Schmelzer, B; Grünwald-Gruber, C; Altmann, F; Gasser, B; Mattanovich, D;

  Event: ESIB – European Summit of Industrial Biotechnology

• Year: 2016 -  The impact of ERAD on recombinant protein secretion in yeast

  Autoren: Zahrl, R; Pfeffer, M; Mattanovich, D; Gasser, B;

  Event: ESIB 2016

• Year: 2016 -  Studying epigenetic regulation in fast and slow growing Pichia pastoris

  Autoren: De, S; Rebnegger, C; Mattanovich, D; Gasser, B;

  Event: ESIB 2016

• Year: 2016 -  pichiagenome.org - Database & Genome Browser

  Autoren: Tatto, N; Valli, M; Mattanovich, D; Gasser, B; Graf, A;

  Event: ESIB 2016

• Year: 2016 -  Synthetic biology toolbox and application for recombinant protein production in Pichia pastoris; Golden Gate Cloning and CRISPR/Cas9

  Autoren: Prielhofer, R; Barrero, J; Steuer, S; Zahrl, R; Baumann, K; Heistinger, L; Jarych, D; Zehetbauer, F; Mattanovich, M; Steiger, M; Marx, H; Sauer, M; Mattanovich, D; Gasser, B;

  Event: ESIB 2016

• Year: 2016 -  Secretome diversity of Pichia pastoris in the presence of different carbon sources

  Autoren: Hohlweg, J; Gruber, C; Altmann, F; Valli, M; Mattanovich, D; Gasser, B;

  Event: ESIB 2016

• Year: 2016 -  Studying epigenetic regulation in fast and slow growing Pichia pastoris

  Autoren: De, S; Rebnegger, C; Mattanovich, D; Gasser, B;

  Event: ECB17 - 17th European Biotechnology Congress

• Year: 2016 -  Engineering Pichia pastoris towards alternative carbon sources

  Autoren: Gaßler, T; Steiger, M; Gasser, B; Sauer, M; Mattanovich, D

  Event: ESIB 2016

• Year: 2016 -  The impact of intracellular degradation on recombinant protein secretion in yeast

  Autoren: Zahrl, R; Marsalek, L; Pfeffer, M; Mattanovich, D; Gasser, B;

  Event: Pichia 2016

• Year: 2016 -  A winding road to the bud tip - exploring the secretion route of recombinant proteins in Pichia pastoris via live cell microscopy

  Autoren: Puxbaum V., Landes N., Gasser B., Mattanovich D.

  Event: 14th International Congress on Yeasts 2016

• Year: 2016 -  Synthetic biology toolbox and application for recombinant protein production in Pichia pastoris: Golden Gate cloning and CRISPR/Cas9

  Autoren: Prielhofer, R; Barrero, J; Steuer, S; Zahrl, R; Baumann, K; Heistinger, L; Jarych, D; Zehetbauer, F; Mattanovich, M; Steiger, M; Marx, H; Sauer, M; Mattanovich, D; Gasser, B;

  Event: Pichia 2016

• Year: 2016 -  Customizing the amino acid metabolism of Pichia pastoris for recombinant protein production

  Autoren: Rußmayer, H; Buchetics, M; Hohlweg, J; Neubauer, S; Klavins, K; Steiger, M; Graf, A; Köllensperger, G; Hann, S; Sauer, M; Gasser, B; Mattanovich, D;

  Event: 1st ACIB Workshop on Analytical Chemistry 2016

• Year: 2016 -  Curation of the Pichia pastoris genome annotation by integration of RNA-Seq and proteomic data

  Autoren: Valli, M; Peymann, A; Gruber, C; Tatto, N; Mattanovich, D; Gasser, B; Graf, A;

  Event: Pichia 2016

• Year: 2016 -  Synthetic biology toolbox and application for recombinant protein production in Pichia pastoris

  Autoren: Prielhofer, R; Barrero, J; Steuer, S; Zahrl, R; Baumann, K; Heistinger, L; Jarych, D; Mattanovich, D; Gasser, B;

  Event: Third meeting on Applied Synthetic Biology in Europe

• Year: 2016 -  Matching the demand of protein production by metabolic engineering of the central metabolism: lessons learned from cofactor and amino acid metabolism in yeasts

  Autoren: Russmayer, H; Nocon, J.; Hohlweg, J; Steiger, M; Sauer, M; Gasser, B; Mattanovich, D;

  Event: 11th Metabolic Engineering 2016

• Year: 2016 -  Systems-level organization of yeast methylotrophic lifestyle: The xylulose-monophosphate cycle of methanol assimilation utilizes a duplicated methanol inducible enzyme set and is entirely localized to peroxisomes

  Autoren: Rußmayer, H; Buchetics, M; Gruber, C; Valli, M; Grillitsch, K; Modarres, G; Drexler, H; Steiger, M; Daum, G; Graf, A; Altmann, F; Hann, S; Sauer, M; Mattanovich, D; Gasser, B;

  Event: PYFF6 - 6th Conference on Physiology of Yeasts and Filamentous Fungi

• Year: 2015 -  Pichia pastoris regulates its gene-specific response to differtent carbon sources at the transcriptional, rather than the translational, level

  Autoren: Prielhofer, Roland, Cartwright, Stephanie, Graf, Alexandra, Valli, Minoska, Mattanovich, Diethard, Gasser, Brigitte

  Event: ACIB Science Days 2015

• Year: 2015 -  The Pichia pastoris secretome in fed-batch cultivations is carbon source independent

  Autoren: Hohlweg, Jonas, Gruber, Clemens, Altmann, Friedrich, Valli, Minoska, Mattanovich, Diethard, Gasser, Brigitte

  Event: ACIB Science Days 2015

• Year: 2015 -  The impact of degradative pathways on recombinant protein secretion in Pichia pastoris

  Autoren: Zahrl, Richard; Pfeffer, Martin; Mattanovich, Diethard; Gasser, Brigitte

  Event: ISSY32 - 32nd International Specialized Symposium on Yeasts

• Year: 2015 -  The impact of degradative pathways on recombinant protein secretion in Pichia pastoris

  Autoren: Zahrl, Richard, Peffer, Martin, Mattanovich, Dietahard, Gasser, Brigitte

  Event: International Specialized Symposium on Yeast 2015

• Year: 2015 -  Expression of C-terminal Fab fragment variants: the host determines the best variant

  Autoren: Goengrich, Rebecca, Kiziak, Christoph, Mattanovich, Diethard, Gasser, Brigitte

  Event: 8th Conference on Recombinant Protein Production RPP8 2015

• Year: 2015 -  The impact of ERAD on recombinant protein secretion in yeast

  Autoren: Zahrl, Richard, Pfeffer, Martin, Mattanovich, Diethard, Gasser, Brigitte

  Event: Pichia postoris Aft1 - a novel transcription factor, enhancing recombinant protein secretion

• Year: 2015 -  Tools for gene expression in Pichia pastoris

  Autoren: Heistinger, Lina, Gasser, Brigitte, Mattanovich, Diethard

  Event: 8th Conference on Recombinant Protein Production RPP8 2015

• Year: 2015 -  Regulation of mating in the methylotophic yeast Pichia pastoris

  Autoren: Heistinger, Lina, Gasser, Brigitte, Mattanovich, Diethard

  Event: 27th International Conference on Yeast Genetics and Molecular Biology ICYGMB 2015

• Year: 2015 -  Regulation of mating in the methylotrophic yeast Pichia pastoris

  Autoren: Heistinger, L; Gasser, B; Mattanovich, D

  Event: 27th International Conference on Yeast Genetics and Molecular Biology ICYGMB 2015

• Year: 2015 -  The xyluloaw-monophoaphate cyl of methanol assimilation utilizes of duplicate mehtanol inducible enzyme set and is entireley localized to peroxicomes

  Autoren: Gasser, Brigitte

  Event: 27th International conference on yeast genetics and molecular biology 2015

• Year: 2015 -  Secretome diversity of Pichia Pastoris in the presence of different carbon sources

  Autoren: Hohlweg, J; Gruber, C; Altmann, F; Valli, M; Mattanovich, D; Gasser, B

  Event: 27th International Conference on Yeast Genetics and Molecular Biology ICYGMB 2015

• Year: 2015 -  Follow the protein: the secretory pathway of recombinant proteins in Pichia pastoris tracked via live cell microscopy

  Autoren: Puxbaum V., Landes N., Maccani A., Kunert R., Gasser B., Mattanovich D.

  Event: 6th International Conference on Analysis of Microbial Cells at the Single Cell Level 2015

• Year: 2015 -  Pichia pastoris regulates its gene-specific response to different carbon sources at the transcriptional, rather than the translational, level

  Autoren: Prielhofer, Roland, Cartwright, Stephanie, Graf, Alexandra, Valli, Minoska, Bill, Roslyn, Mattanovich, Diethard, Gasser, Brigitte

  Event: 8th Conference on Recombinant Protein Production RPP8 2015

• Year: 2015 -  Mehtanol induced changes on the transciptome, proteome, metabolome and fluxome of Pichia pastoris

  Autoren: Russmayer, Hannes, Buchetics, Markus, Graf, Alexandra, Valli, Minoska, Gruber, Clemens, Modarres, Gerda, Altmann, Friedrich, Guerrasio, Raffaelle, Klavins, Kristaps, Neubauer, Stefan, Stiefer, Matthias, Chalabi Ali Al, Krebiehl, Guido, Sonntag, Denise, Haberhauer-Troyer, Christina, Köllensperger, Gunda, Hann Stephan, Sauer, Michael, Gasser, Brigitte, Mattanovich, Diethard

  Event: 8th Conference on Recombinant Protein Production RPP8 2015

• Year: 2015 -  The xylulose-monophosphate cycle of methanol assimilation utilizes a duplicated methanol inducible enzyme set and is entirely localized to peroxisomes

  Autoren: Gasser, B; Russmayer, H; Buchetics, M; Gruber, C; Valli, M; Grillitsch, K; Modarres, G; Drexler, H; Steiger, M; Daum, G; Graf, AB; Altmann, F; Hann, S; Sauer, M; Mattanovich, D

  Event: 27th International Conference on Yeast Genetics and Molecular Biology ICYGMB 2015

• Year: 2015 -  Tracking secretion of recombinant proteins in Pichia pastoris using live cell microscopy

  Autoren: Puxbaum V., Landes N., Maccani A., Kunert R., Gasser B., Mattanovich D.

  Event: EMBO/EMBL Symposium Seeing is Believing - Imaging the Processes of Life

• Year: 2015 -  Follow the protein: the secretory pathway of recombinant proteins in Pichia pastoris tracked via live cell microscopy

  Autoren: Puxbaum V., Landes N., Maccani A., Kunert R., Gasser B., Mattanovich D.

  Event: 6th International Conference on Analysis of Microbial Cells at the Single Cell Level 2015

• Year: 2015 -  The Pichia pastoris secretome in fed-batch cultivations is carbon source independent

  Autoren: Hohlweg, Jonas, Gruber, Clemens, Altmann, Friedrich, Valli, Minoska, Mattanovich, Diethard, Gasser, Brigitte

  Event: 8th Conference on Recombinant Protein Production RPP8 2015

• Year: 2015 -  Dissection of growth rate and cell cycle dependent gene regulation in Pichia pastoris

  Autoren: Rebnegger, Corinna, Hohlweg, Jonas, Graf Alexandra, Valli, Minoska, Gasser, Brigitte and Mattanovich, Diethard

  Event: 8th Conference on Recombinant Protein Production RPP8 2015

• Year: 2015 -  Secretome diversity of Pichia pastoris in the presence of different carbon sources

  Autoren: Hohlweg, Jonas, Gruber, clemens, Altmann, Friedrich, Valli, Minoska, Mattanovich, Diethard, Gasser, Brigitte

  Event: 27th International Conference on Yeast Genetics and Molecular Biology ICYGMB 2015

• Year: 2014 -  Model based engineering of Pichia pastoris central metabolism enhances recombinant protein production

  Autoren: Nocon, Justyna; Steiger, Matthias; Pfeffer, Martin; Sohn, Seung Bum; Kim, Tae Yong; Maurer, Michael; Russmayer, Hannes; Pflügl, Stefan; Ask, Magnus; Haberhauer-Troyer, Christina; Ortmayr, Karin; Hann, Stephan; Köllensperger, Gunda; Gasser, Brigitte; Lee, Sang Yup; Mattanovich, Diethard

  Event: ECB16 2014

• Year: 2014 -  "Model based engineering of Pichia pastoris central metabolism enhances recombinant protein production"

  Autoren: Hoppe, Frederik; Schillinger, Harald; Schrafvogl, Rudolf; Hutter, Melanie; Kunert, Renate; Eyer, Kurt; Maurer, Michael

  Event: 5th International Conference on Biomolecular Engineering (ICBE)

• Year: 2014 -  Redox regulation in ER and cytosol in response to increased oxidative protein folding and ER stress

  Autoren: Delic, Maricela; Puxbaum, Verena; Mattanovich, Diethard; Gasser, Brigitte

  Event: EMBO Workshop Protein and lipid function in secretion and endocytosis

• Year: 2014 -  Redox regulation in ER and cytosol in response to increased oxidative protein folding and ER stress

  Autoren: Delic, M; Borth, N; Landes, N; Maccani, A; Ernst, W; Puxbaum, V; Mattanovich, D; Gasser, B

  Event: CHOgenome Workshop 2014

• Year: 2014 -  Multistep processing of the secretion leader of the CRISP family member Epx1 in Pichia pastoris and implications on protein localization

  Autoren: Heiss, Silvia; Puxbaum, Verena; Gruber, Clemens; Altmann, Friedrich; Mattanovich, Diethard and Gasser, Brigitte

  Event: EMBO Workshop Protein and lipid function in secretion and endocytosis

• Year: 2014 -  Systems biology & Systems biotechnology of Pichia pastoris

  Autoren: Gasser, Brigitte

  Event: ECB16 2014

• Year: 2014 -  Cross-species comparison of recombinant protein secretion in CHO cells and Pichia pastoris

  Autoren: Landes, Nils; Maccani, Andreas; Leitner, Christian; Maurer, Michael; Gasser, Brigitte; Ernst, Wolfgang; Kunert, Renate; Mattanovich, Diethard

  Event: CHOgenome Workshop 2014

• Year: 2014 -  Cross-species comparison of recombinant protein secretion in CHO cells and Pichia pastoris

  Autoren: Landes, Nils; Maccani, Andreas; Leitner, Christian; Maurer, Michael; Graf, Alexandra; Valli, Minoska; Gruber, Clemens; Modarres, Gerda; Altmann, Friedrich; Gasser, Brigitte; Ernst, Wolfgang; Kunert, Renate; Mattanovich, Diethard

  Event: ECB16 2014

• Year: 2014 -  Influence of recombinant protein expression on the proteome of Pichia pastoris

  Autoren: Gruber, Clemens; Landes, Nils; Valli, Minoska; Modarres, Gerda; Gasser, Brigitte; Graf, Alexandra; Altmann, Friedrich; Mattanovich, Diethard

  Event: 6th ÖGMBT Annual Meeting 2014 - Life Sciences meet Entrepreneurship

• Year: 2014 -  Control of redox conditions in the endoplasmic reticulum by redox-active proteins and transporters

  Autoren: Delic, Maricela; Puxbaum, Verena; Gasser, Brigitte; Mattanovich, Diethard

  Event: EMBO Conference 2014 - The Endoplasmic Reticulum (ER) as a hub for organelle communication

• Year: 2014 -  The impact of ERAD on recombinant protein secretion in yeast

  Autoren: Zahrl, Richard; Pfeffer, Martin; Mattanovich, Diethard; Gasser, Brigitte

  Event: EMBO Conference 2014 - The Endoplasmic Reticulum (ER) as a hub for organelle communication

• Year: 2014 -  Methanol induced changes on the transcriptome, proteome, metabolome and fluxome of Pichia pastoris

  Autoren: Rußmayer, Hannes; Buchetics, Markus; Graf, Alexandra; Valli, Minoska; Gruber, Clemens; Modarres, Gerda; Altmann, Friedrich; Guerrasio, Raffaelle; Klavins, Kristaps; Neubauer, Stefan; Steiger, Matthias; Chalabi, Ali Al; Krebiehl, Guido; Sonntag, Denise; Haberhauer-Troyer, Christina; Köllensperger, Gunda; Hann, Stephan; Sauer, Michael; Gasser, Brigitte; Mattanovich, Diethard

  Event: ACIB-UAB Workshop - Systems Biology for Metabolic Engineering

• Year: 2014 -  Combinatorial genetic engineering in Pichia pastoris GoldenGate vs. Cre/loxP-based cloning approaches

  Autoren: Baumann, Kristin; Barrero Peña, Juanjo; Marx, Hans; Gasser, Brigitte and Mattanovich, Diethard

  Event: ACIB-UAB Workshop - Systems Biology for Metabolic Engineering

• Year: 2014 -  Proteomic study of Pichia pastoris cell compartments

  Autoren: Gruber, C; Grillitsch, K-H; Klug, L; Valli, M; Gasser, B; Mattanovich, D; Daum, G; Altmann, F

  Event: APRS 2014

• Year: 2014 -  Multistep processing of the secretion leader of the CRISP family member Epx1 in Pichia pastoris and implications on protein localization

  Autoren: Heiss, Silvia; Puxbaum, Verena; Gruber, Clemens; Altmann, Friedrich; Mattanovich, Diethard and Gasser, Brigitte

  Event: ACIB-UAB Workshop - Systems Biology for Metabolic Engineering

• Year: 2014 -  Methanol induced changes on the transcriptome, proteome, metabolome and fluxome of Pichia pastoris

  Autoren: Rußmayer, Hannes; Buchetics, Markus; Graf, Alexandra; Valli, Minoska; Gruber, Clemens; Modarres, Gerda; Altmann, Friedrich; Guerrasio, Raffaelle; Klavins, Kristaps; Neubauer, Stefan; Steiger, Matthias; Chalabi, Ali Al; Krebiehl, Guido; Sonntag, Denise; Haberhauer-Troyer, Christina; Köllensperger, Gunda; Hann, Steph

  Event: ACIB-UAB Workshop - Systems Biology for Metabolic Engineering

• Year: 2014 -  Proteomic study of Pichia pastoris cell compartments

  Autoren: Gruber, C; Landes, N; Valli, M; Modarres, G; Gasser, B; Graf, AB; Altmann, F; Mattanovich, D

  Event: 6th ÖGMBT Annual Meeting 2014 - Life Sciences meet Entrepreneurship

• Year: 2013 -  Redox regulation in ER and cytosol differs during oxidative protein folding *** ER stress

  Autoren: Delic, M; Mattanovich, D; Gasser, B

  Event: 26th International Conference on Yeast Genetics and Molecular Biology 2013

• Year: 2013 -  Metabolic model-based prediction of engineering targets for increased production of heterologous proteins

  Autoren: Nocon, J., Pfeffer, M., Sohn, S.B., Kim, T.Y., Maurer, M., Gasser, B., Lee, S.Y., Mattanovich, D.

  Event: 7th Conference on Recombinant Protein Production RPP7 2013

• Year: 2013 -  Overexpression of the redox transcription factor Yap1 modifies intracellular redox conditions and enhances recombinant protein secretion

  Autoren: Delic, M; Rebnegger, C; Graf, AB; Mattanovich, D; Gasser, B.

  Event: 7th Conference on Recombinant Protein Production RPP7 2013

• Year: 2013 -  Regulation of recombinant protein secretion in relation to growth in Pichia pastoris

  Autoren: Rebnegger, C; Valli, M; Graf, A; Gasser, B; Maurer, M; Mattanovich, D

  Event: 26th International Conference on Yeast Genetics and Molecular Biology 2013

• Year: 2013 -  Folding and secretion of heterologous proteins in yeasts – A genome scale perspective

  Autoren: Gasser, B.

  Event: 5th Conference on Physiology of Yeast and Filamentous Fungi PYFF5 2013

• Year: 2013 -  Influence of carbon source on the Pichia pastoris proteome

  Autoren: C. Gruber1)2), M. Buchetics1)3), G. Modarres1)3),B. Gasser1)3), A.B.Graf1)4), F. Altmann1)2)and D. Mattanovich1)3) Gruber, C; Buchetics, M; Modarres, G; Gasser, B; Graf, AB; Altmann, F; Mattanovich, M

  Event: 11th Austrian Proteomic Research Symposium

• Year: 2013 -  Cross-species comparison of recombinant protein secretion in CHO cells and Pichia pastoris

  Autoren: Landes, N; Maccani, A; Leitner, C; Maurer, M; Gasser, B; Ernst, W; Kunert, R; Mattanovich, D.

  Event: 7th Conference on Recombinant Protein Production RPP7 2013

• Year: 2013 -  Induction without methanol: Novel regulated promoters enable high- level expression in Pichia pastoris

  Autoren: Prielhofer, R; Maurer, M; Klein, J; Wenger, J; Kiziak, C; Gasser, B; Mattanovich, D.

  Event: 7th Conference on Recombinant Protein Production RPP7 2013

• Year: 2013 -  Regulation of recombinant protein secretion in relation to cell growth in the methylotrophic yeast Pichia pastoris

  Autoren: Rebnegger, C; Graf, AB; Valli, M; Buchetics, M; Gasser, B; Maurer, M; Mattanovich, D.

  Event: 7th Conference on Recombinant Protein Production RPP7 2013

• Year: 2013 -  Multistep processing of the secretion leader of the CRISP family member Epx1 in Pichia pastoris and implications on protein localization

  Autoren: Gasser, B; Heiss, S; Puxbaum, V; Gruber, C; Altmann, F; Mattanovich, D

  Event: 26th International Conference on Yeast Genetics and Molecular Biology 2013

• Year: 2013 -  Metabolic model-based prediction of engineering targets for increased production of heterologous proteins

  Autoren: Nocon, J; Pfeffer, M; Sohn, SB; Kim, TY;, Maurer, M; Rußmayer, H; Steiger, M; Haberhauer-Troyer, C; Hann, S; Köllensperger, G;, Gasser, B; Lee, SY; Mattanovich, D.

  Event: Quantitative Biology: Current concepts and tools for microbial strain and process development

• Year: 2012 -  Oxidative protein folding and unfolded protein response elicit differing redox regulation in endoplasmic reticulum and cytosol of yeast

  Autoren: Delic, M; Rebnegger, C; Wanka, F; Puxbaum, V; Mattanovich, D; Gasser, B

  Event: Physiology of the ER

• Year: 2012 -  Overexpression of the redox transcription factor Yap1 modifies intracellular redox conditions and enhances recombinant protein secretion

  Autoren: Delic, M; Rebnegger, C; Alexandra B. Graf, AB; Mattanovich, D; Gasser, B.

  Event: 13th International Congress on Yeasts 2012

• Year: 2012 -  Reverse Engineering of Protein Secretion by Uncoupling of Cell Cycle Phases From Growth

  Autoren: Buchetics, M., Dragosits, M., Maurer, M., Rebnegger, C., Porro, D., Sauer, M., Gasser, B., Mattanovich, D

  Event: Pichia 2012

• Year: 2012 -  Evaluation of recoveries of cell extraction and overall sample preparation using a U13C cell extract

  Autoren: Neubauer, S., Klavins, K., Haberhauer-Troyer, C., Steiger, M.G., Gasser, B., Sauer, M., Mattanovich, D., Hann, S. and Köllensperger, G.

  Event: 60th ASMS Conference on Mass Spectrometry and Allied Topics 2012

• Year: 2012 -  Development of synthetic protein production platforms based on systems biology

  Autoren: Gasser, B., Mattanovich, D.

  Event: Applied Synthetic Biology in Europe 2012

• Year: 2011 -  Monitoring intracellular redox conditions in the endoplasmic reticulum of living yeasts

  Autoren: Delic, M., Mattanovich, D., Gasser, B.

  Event: 6th Conference on Recombinant Protein Production RPP6 2011

• Year: 2011 -  Characterizing secretion behaviour of recombinant proteins in Pichia pastoris

  Autoren: Puxbaum, V., Ertl, S., Gasser, B., Mattanovich, D.

  Event: Non-Conventional Yeasts in the Postgenomic Era NCY 2011

• Year: 2011 -  Characterization of cell cycle mutants in Pichia pastoris

  Autoren: Schneider, F., Buchetics, M., Maurer, M., Mattanovich, D., Gasser, B.

  Event: 25th International Conference on Yeast Genetics and Molecular Biology 2011

• Year: 2011 -  The stressful life of Pichia pastoris producing recombinant protein

  Autoren: Mattanovich, D., Gasser, B., Dragosits, M., Delic, M., Graf, A.B., Maurer, M., Sauer, M., Baumann, K., Ferrer, P.,

  Event: 6th Conference on Recombinant Protein Production RPP6 2011

• Year: 2011 -  Environmental and intrinsic stress in Pichia pastoris producing recombinant protein

  Autoren: Mattanovich, D., Gasser, B., Dragosits, M., Delic, M., Graf, A.B., Maurer, M., Sauer, M., Baumann, K., Ferrer, P.

  Event: FEMS 2011 - 4th Congress of European Microbiologists

• Year: 2011 -  Characterizing secretion behaviour of recombinant proteins in Pichia pastoris

  Autoren: Puxbaum, V., Ertl, S., Gasser, B., Mattanovich, D.

  Event: Non-Conventional Yeasts in the Postgenomic Era NCY 2011

• Year: 2011 -  Identification and characterization of the secretory cysteine-rich protein family member Epx1 in Pichia pastoris

  Autoren: Heiss, S., Dragosits, M., Marx, H., Maurer, M., Puxbaum, V., Mattanovich, D., Gasser, B.

  Event: 25th International Conference on Yeast Genetics and Molecular Biology 2011

• Year: 2011 -  Reverse Engineering of Protein Secretion by Uncoupling of Cell Cycle Phases From Growth

  Autoren: Buchetics M., Dragosits M., Maurer M., Rebnegger C., Porro D., Sauer M., Gasser B., Mattanovich D.

  Event: 6th Conference on Recombinant Protein Production RPP6 2011

• Year: 2011 -  Oxidative protein folding and unfolded protein response elicit different redox regulation in ER and cytosol of the yeast Pichia pastoris

  Autoren: Delic, M., Rebnegger, C., Wanka, F., Haberhauer-Troyer, C., Köllensperger, G., Hann, S., Mattanovich, D., Gasser, B.

  Event: Non-Conventional Yeasts in the Postgenomic Era NCY 2011

• Year: 2011 -  Metabolite analyses in the protein production host Pichia pastoris

  Autoren: Rußmayer, H., Guerrasio, R., Klavins, K., Neubauer, S., Steiger, M., Haberhauer-Troyer C., Koellensperger, G., Hann, S., Sauer, M., Gasser, B., Mattanovich, D.

  Event: 3rd ÖGMBT Annual Meeting 2011

• Year: 2011 -  Oxidative protein folding and unfolded protein response elicit different redox regulation in ER and cytosol of yeast

  Autoren: Delic, M., Rebnegger, C., Wanka, F., Haberhauer-Troyer, C., Köllensperger, G., Hann, S., Mattanovich, D., Gasser, B.

  Event: ESF-EMBO Conference on Glutathione and Related Thiols in Living Cells 2011

• Year: 2011 -  Novel promoters for protein production in Pichia pastoris

  Autoren: Stadlmayr*, G., Mecklenbräuker*, A., Rothmüller, M., Maurer, M., Sauer, M., Mattanovich, D., Gasser, B.

  Event: 6th Conference on Recombinant Protein Production RPP6 2011

• Year: 2011 -  Engineering of biotin prototrophy in Pichia pastoris for robust protein production processes

  Autoren: Gasser, B., Dragosits, M., Mattanovich D.

  Event: 6th Conference on Recombinant Protein Production RPP6 2011

• Year: 2011 -  Genome-scale modeling of the methylotrophic yeast Pichia pastoris for heterologous protein production

  Autoren: Sohn*, S.B., Graf*, A. B., Kim, T. Y., Gasser, B., Maurer, M., Ferrer, P., Mattanovich, D., Lee, S. Y.

  Event: 6th Conference on Recombinant Protein Production RPP6 2011

• Year: 2011 -  Identification and characterization of the secretory cysteine-rich protein family member Epx1 in Pichia pastoris

  Autoren: Heiss, S., Dragosits, M., Marx, H., Maurer, M., Puxbaum, V., Mattanovich, D., Gasser, B.

  Event: 25th International Conference on Yeast Genetics and Molecular Biology 2011

• Year: 2010 -  Engineering of biotin prototrophy in Pichia pastoris for robust protein production processes

  Autoren: Gasser, B., Dragosits, M., Mattanovich D..

  Event: 4th Conference on Physiology of Yeast and Filamentous Fungi PYFF4 2010

• Year: 2010 -  Engineering of biotin prototrophy in Pichia pastoris for robust protein production processes

  Autoren: Gasser, B., Dragosits, M., Mattanovich D.

  Event: 13th Metabolic Engineering 2010

• Year: 2010 -  Genome, secretome and glucose transport highlight unique features of the protein production host Pichia pastoris

  Autoren: Mattanovich, D., Graf, A.B., Stadlmann, J., Dragosits, M., Redl, A., Maurer, M., Sauer, M., Altmann, F., Gasser, B.

  Event: 4th Conference on Physiology of Yeast and Filamentous Fungi PYFF4 2010

• Year: 2010 -  Systems Biotechnology for Protein Production in Pichia pastoris

  Autoren: Mattanovich, D., Graf, A.B., Stadlmann, J., Dragosits, M., Redl, A., Maurer, M., Sauer, M., Altmann, F., Gasser, B..

  Event: Systems Biology of Microorganisms

• Year: 2010 -  Genome sequence, secretome and sugar transport of the protein production host Pichia pastoris

  Autoren: Mattanovich, D., Graf, A.B., Stadlmann, J., Dragosits, M., Redl, A., Maurer, M., Sauer, M., Altmann, F., Gasser, B..

  Event: Systems Biology of Microorganisms

• Year: 2010 -  Monitoring intracellular redox conditions in the endoplasmic reticulum of living yeasts

  Autoren: Delic, M., Mattanovich, D.,Gasser B.

  Event: 4th Conference on Physiology of Yeast and Filamentous Fungi PYFF4 2010

• Year: 2009 -  Proteomic and Transcriptomic Analysis of the Adaption of Pichia pastoris Cells to Various Environmental Conditions

  Autoren: Dragosits Martin, Johannes Stadlmann, Alexandra Graf, Joan Albiol, Kristin Baumann, Brigitte Gasser, Michael Sauer, Friedrich Altmann, Pau Ferrer, Diethard Mattanovich

  Event: MICROBIAL STRESS 2009

• Year: 2009 -  Engineering of biotin prototrophy in yeasts

  Autoren: Gasser Brigitte, Mattanovich Diethard

  Event: 25th International Conference on Yeast Genetics & Molecular Biology 2009

• Year: 2009 -  Stress in recombinant protein producing yeasts

  Autoren: Brigitte Gasser, Martin Dragosits, Alexandra Graf, Michael Maurer, Hans Marx, Astrid Mecklenbräuker, Michael Sauer, Diethard Mattanovich

  Event: MICROBIAL STRESS 2009

• Year: 2009 -  Measuring intracellular redox conditions in recombinant protein producing Pichia pastoris strains

  Autoren: Delic, M., Mattanovich, D., Gasser, B.

  Event: 25th International Conference on Yeast Genetics & Molecular Biology 2009

• Year: 2009 -  Engineering Pichia pastoris in the genomics era

  Autoren: Mattanovich Diethard, Gasser Brigitte, Graf Alexandra , Dragosits Martin, Sauer Michael , Maurer Michael,

  Event: 25th International Conference on Yeast Genetics & Molecular Biology 2009

• Year: 2009 -  Genome sequence, secretome and sugar transport of the protein production host Pichia pastoris

  Autoren: Mattanovich Diethard, Graf Alexandra, Stadlmann Johannes, Dragosits Martin, Redl Andreas, Maurer Michael, Sauer Michael, Altmann Friedrich, Gasser Brigitte

  Event: 25th International Conference on Yeast Genetics & Molecular Biology 2009

• Year: 2009 -  Genome scale engineering of protein production in Pichia pastoris

  Autoren: Mattanovich Diethard; Graf Alexandra; Dragosits Martin; Stadlmann Johannes; Redl Andreas; Sauer Michael; Maurer Michael; Altmann Friedrich; Gasser Brigitte

  Event: Autumn Meeting of the Society for General Microbiology 2009

• Year: 2009 -  Genome sequence, secretome and sugar transport of the protein production host Pichia pastoris

  Autoren: Mattanovich, D; Graf, A; Stadlmann, J; Dragosits, M; Redl, A; Maurer, M; Sauer, M; Altmann, F; Gasser, B.

  Event: 14th European Congress on Biotechnology 2009

• Year: 2009 -  Yeast Systems Biotechnology for the Production of Heterologous Proteins

  Autoren: Diethard Mattanovich, Martin Dragosits, Alexandra Graf, Andreas Redl, Johannes Stadlmann, Michael Maurer, Kristin Baumann, Joan Sola, Pau Ferrer, Friedrich Altmann, Michael Sauer, Brigitte Gasser

  Event: 16th Biochemical Engineering 2009 - Past, Present, and Future of Biochemical Engineering

• Year: 2008 -  Monitoring proteome and transcriptome of recombinant Pichia pastoris at different cultivation temperatures

  Autoren: Martin Dragosits, Johannes Stadlmann, Michael Maurer, Kristin Baumann, Joan Albiol Sala, Alexandra Graf, Brigitte Gasser, Michael Sauer, Pau Ferrer, Friedrich Altmann, and Diethard Mattanovich

  Event: 5th EFB Meeting on Recombinant Protein Production RPP 2008

• Year: 2008 -  Physiological characterization and strain engineering of Pichia pastoris by transcriptomics and proteomics

  Autoren: Gasser Brigitte

  Event: 4th Swiss-Czech Symposium BioTech 2008

• Year: 2008 -  Novel promoters for protein production in Pichia pastoris

  Autoren: Gerhard Stadlmayr, Astrid Mecklenbräuker, Marion Rothmüller, Michael Sauer, Diethard Mattanovich, Brigitte Gasser

  Event: 5th EFB Meeting on Recombinant Protein Production RPP 2008

• Year: 2008 -  A Chemostat based Study on the Influence of Temperature on the Physiology of Recombinant Pichia pastoris

  Autoren: Martin Dragosits, Johannes Stadlmann, Michael Maurer, Brigitte Gasser, Michael Sauer and Diethard Mattanovich

  Event: Workshop Functional Genomics and Industrial Biocatalysis 2008

• Year: 2008 -  High throughput screening for factors enhancing protein secretion secretion in yeasts

  Autoren: Brigitte Gasser*, Gerhard Stadlmayr*, Michael Sauer, Michael Maurer, Katrin Benakovitsch, Diethard Mattanovich

  Event: 5th EFB Meeting on Recombinant Protein Production RPP 2008

• Year: 2008 -  High throughput screening for factors enhancing protein production and secretion with Pichia pastoris

  Autoren: Gerhard Stadlmayr, Katrin Benakovitsch, Brigitte Gasser, Michael Sauer, Diethard Mattanovich

  Event: 4th Swiss-Czech Symposium BioTech 2008

• Year: 2008 -  A proteomics and transcriptomics approach to the study of heterologous protein production in Pichia pastoris under different oxygen conditions

  Autoren: Baumann K, Dragosits M, Stadlmann J, Graf A, Maurer M, Gasser B, Altmann F,Mattanovich D, Ferrer P

  Event: 5th Conference on Recombinant Protein Production 2008

• Year: 2008 -  Monitoring proteome and transcriptome of recombinant Pichia pastoris at different cultivation temperatures

  Autoren: Dragosits M, Stadlmann J, Maurer M, Baumann K, Albiol J, Graf A, Gasser B, Sauer M, Ferrer P, Altmann F, Mattanovich D

  Event: 5th International Conference on Recombinant Protein Production

• Year: 2008 -  Physiological characterization and strain engineering of Pichia pastoris by transcriptomics and proteomics

  Autoren: Gasser B, Dragosits M, Graf A, Sauer M, Maurer M, Stadlmayr G, Mattanovich D

  Event: Workshop Functional Genomics and Industrial Biocatalysis 2008

• Year: 2008 -  High throughput screening for factors enhancing protein production and secretion with Pichia pastoris

  Autoren: Gerhard Stadlmayr, Katrin Benakovitsch, Brigitte Gasser, Michael Sauer, Diethard Mattanovich

  Event: 4th International Conference on Analysis of Microbial Cells at the Single Cell Level 2008

• Year: 2008 -  Application of Pichia pastoris microarrays leads to novel insights into the Unfolded Protein Response

  Autoren: Gasser B., Graf A., Dragosits M., Michael S., Leparc G., Kreil D. P., Mattanovich D

  Event: 12th International Congress on Yeasts ICY 2008

• Year: 2008 -  Novel promoters for protein production in Pichia pastoris

  Autoren: Gerhard Stadlmayr, Brigitte Gasser, Marion Rothmüller, Michael Sauer, Diethard Mattanovich

  Event: 4th Swiss-Czech Symposium BioTech 2008

• Year: 2008 -  Novel insights into the unfolded protein response using Pichia pastoris specific DNA microarrays

  Autoren: Brigitte Gasser*, Alexandra Graf*, Martin Dragosits, Michael Sauer, Germán G. Leparc, Thomas Tüchler, David P. Kreil, Diethard Mattanovich

  Event: 5th EFB Meeting on Recombinant Protein Production RPP 2008

• Year: 2007 -  Molecular characterization and engineering of Pichia pastoris as a platform for antibody (fragment) production.

  Autoren: Gasser B., Sauer M., Benakovitsch K., Maurer M., Stadlmayr G., Dragosits M., Mattanovich D.

  Event: 15th Biochemical Engineering 2007

• Year: 2007 -  Novel helper factors for protein secretion in yeasts

  Autoren: Gasser B., Sauer M., Maurer M., Benakovitsch K., Mattanovich D.

  Event: 3rd EFB Conference on Physiology of Yeasts and Filamentous Fungi PYFF3 2007

• Year: 2007 -  Proteome regulation of Pichia pastoris expressing recombinant human antibody fragments

  Autoren: Martin Dragosits, Johannes Stadlmann, Michael Maurer, Brigitte Gasser, Michael Sauer, Diethard Mattanovich

  Event: 13th European Congress on Biotechnology 2007

• Year: 2006 -  Monitoring of transcript regulation and protein production related stress responses in Pichia pastoris secreting Fab antibody fragments

  Autoren: Gasser B., Maurer M., Sauer M., Saloheimo M., Rautio J., Penttila M., Mattanovich D.

  Event: 4th Recombinant Protein Production Meeting RPP EFB 2006 - A Comparative View on Host Physiology

• Year: 2006 -  High level expression of a humanised Ab2/3H6 Fab in Pichia pastoris.

  Autoren: Gach, J.,Maurer, M., Quendler, H., Gasser, B., Löschel, M., Mattanovich, D., Katinger, H., Kunert, R.

  Event: Recombinant Antibodies

• Year: 2006 -  A rational approach to optimize feed profiles for the maximization of productivity of secreted proteins expressed in Pichia pastoris

  Autoren: Michael Maurer, Brigitte Gasser, Manfred Kühleitner, Diethard Mattanovich

  Event: Bioengineering course

• Year: 2006 -  Identification of Physiological Bottlenecks hampering Heterologous Protein Expression in Pichia pastoris by Genomic and Proteomic Analysis

  Autoren: Dragosits M, Gasser B, Maurer M, Kunert R and Mattanovich D

  Event: 3rd Summer School in Proteomic Basics 2006 - Exploring the Diversity of Proteins

• Year: 2006 -  In vitro and in vivo characterization of an antiidiotypic antibody variants directed against the HIV-neutralizing mAb 2F5

  Autoren: Kunert, R., Gach, J., Preis, S., Löschel M., Weik, R., Ferko, B., Stiegler, G., Gasser, B., Mattanivich, D., Katinger, H.

  Event: Human Antibodies and Hybridomas 2006

• Year: 2006 -  Monitoring of transcript regulation and protein production related stress responses in Pichia pastoris secreting Fab antibody fragments.

  Autoren: Gasser, B., Maurer, M., Sauer, M., Saloheimo, M., Rautio, J., Penttila, M., Mattanovich, D.

  Event: Systems Biology of Yeasts – From Models to Applications

• Year: 2006 -  A rational approach to optimize feed profiles for the maximization of productivity of secreted proteins expressed in Pichia pastoris

  Autoren: Maurer M., Gasser B., Kühleitner M., Mattanovich D.

  Event: 4th Recombinant Protein Production Meeting RPP EFB 2006 - A Comparative View on Host Physiology

• Year: 2005 -  Impact of environmental and metabolic stresses on recombinant protein production in Pichia pastoris

  Autoren: Gasser, B.

  Event: Friday Seminar Series - VTT Biotechnology

• Year: 2005 -  Multiple flow cytometry analysis as a tool for the study of microbial fermentations

  Autoren: Maurer M., Gasser B., Benakovitsch K., Borth N. Mattanovich D.

  Event: 3rd International EFB Conference 2005 - Analysis of Microbial Cells at the Single Cell Level

• Year: 2005 -  Anti-idiotypic antibodies, an alternatve strategy against HIV-1

  Autoren: Johannes Gach, Boris Ferko, Brigitte Gasser, Diethardt Mattanovich, Hermann Katinger, Renate Kunert

  Event: 60 Year Anniversary, Institute of Applied Microbiology IAM 2005

• Year: 2005 -  High throughput methods for strain improvement - Flow Cytometry & FACS

  Autoren: Maurer M., Gasser B., Benakovitsch K., Valli M., Borth N., Mattanovich D.

  Event: 60 Year Anniversary, Institute of Applied Microbiology IAM 2005

• Year: 2005 -  Anti-idiotypic antibodies an alternative strategy against HIV-1

  Autoren: Gach, J., Ferko, B., Gasser, B., Mattanovich, D., Katinger, H., Kunert, R.

  Event: 60 Year Anniversary, Institute of Applied Microbiology IAM 2005

• Year: 2005 -  Optimisation of protein secretion in antibody fragment expressing Pichia pastoris

  Autoren: Gasser B., Maurer M., Kunert R., Mattanovich D.

  Event: 60 Year Anniversary, Institute of Applied Microbiology IAM 2005

• Year: 2005 -  Flow cytometric analysis of antibody fragment secreting Pichia pastoris – Detection of folding stress by immunofluorescence

  Autoren: Gasser B., Maurer M., Mattanovich D.

  Event: 3rd International EFB Conference 2005 - Analysis of Microbial Cells at the Single Cell Level

• Year: 2005 -  High throughput methods for strain improvement - Microarrays

  Autoren: Sauer M., Gasser B., Branduardi P., Maurer M., Wernitznig E., Porro D., Mattanovich D.

  Event: 60 Year Anniversary, Institute of Applied Microbiology IAM 2005

• Year: 2005 -  Multiple flow cytometry analysis as a tool for the study of microbial fermentations

  Autoren: Maurer M., Gasser B., Benakovitsch K., Borth N., Mattanovich D.

  Event: Biotech 2005

• Year: 2004 -  Effects of gene dosage, promoters and substrates on unfolded protein stress of recombinant Pichia pastoris

  Autoren: Gasser B., Hohenblum H., Maurer M., Borth N., Mattanovich D.

  Event: EFB Section Meeting “Physiology of Yeasts and Filamentous Fungi II”

• Year: 2004 -  Unfolded protein response in Pichia pastoris expressing the Rhizopus oryzae Lipase under the control of FLD1 promoter.

  Autoren: Resina D., Gasser B., Maurer M., Valero F., Ferrer P., Mattanovich D.

  Event: EFB Section Meeting 2004 - Recombinant Protein Production with Prokaryotic and Eukaryotic Cells III

• Year: 2004 -  Differential gene expression in recombinant Pichia pastoris analysed by heterologous DNA microarray hybridisation

  Autoren: Sauer M., Branduardi P., Gasser B., Valli M., Maurer M., Porro D., Mattanovich D.

  Event: EFB Section Meeting 2004 - Recombinant Protein Production with Prokaryotic and Eukaryotic Cells III