Christa Jakopitsch

Presentations

• Year: 2016 -  Mechanism of hydrogen peroxide to dioxygen oxidation by bifunctional catalase-peroxidase

  Autoren: Obinger, C., Jakopitsch, C., Furtmüller, P. G., Gasselhuber, B., Zamocky, M

  Event: 79th Harden Conference on Oxygen Evolution and Reduction - Common Principles

• Year: 2016 -  Two redox active cofactors are essential for the catalatic activity of catalase-peroxidases

  Autoren: Jakopitsch, C., Gasselhuber, B., Furtmüller, P. G., Obinger, C.

  Event: 13th European Biological Inorganic Chemistry Conference EuroBIC 2016

• Year: 2015 -  The peroxidase-cyclooxygenase superfamily - evolution of structure and function

  Autoren: Obinger, C; Paumann-Page, M; Auer, M; Nicolussi, A; Zamocky, M; Jakopitsch C; Furtmüller P.G;

  Event: 9th International Human Peroxidase Meeting 2015

• Year: 2015 -  Interactions of hydrogen sulfide with myeloperoxidase

  Autoren: Palinkas, Z; Furtmuller, PG; Nagy, A; Jakopitsch, C; Pirker, KF; Magierowski, M; Jasnos, K; Wallace, JL; Obinger, C; Nagy, P

  Event: 3rd European Conference on the Biology of Hydrogen Sulfide (H2S)

• Year: 2015 -  Recombinant production, biochemical and structural investigation of a eukaryotic bifunctional catalase-peroxidase

  Autoren: Gasselhuber, B., Nicolussi, A., Carpena, X., Zamocky, M., Jakopitsch, C., Furtmüller, P.G., Fita, I., Obinger, C.

  Event: 8th Conference on Recombinant Protein Production RPP8 2015

• Year: 2014 -  Hydrogen sulfide functions as reversible inhibitor and electron donor for human myeloperoxidase

  Autoren: Pirker, KF; Palinkas, Z; Furtmuller, PG; Nagy, A; Jakopitsch, C; Obinger, C; Nagy, P

  Event: 12th European Biological Inorganic Chemistry Conference EuroBIC 2014

• Year: 2014 -  Bifunctional eucaryotic catalase-peroxidase - investigating the relation between structure and reaction mechanism

  Autoren: Gasselhuber, B., Nicolussi, A., Carpena, X., Zamocky, M., Jakopitsch, C., Furtmüller, P.G., Fita, I., Obinger, C.

  Event: OxiZymes 2014

• Year: 2014 -  Chlorite inactivates mammalian peroxidases

  Autoren: Jakopitsch, C., Pirker, K.F., Flemmig, J. Hofbauer, S., Furtmüller, P.G., Schlorke, D., Arnhold, J., Obinger, C.

  Event: OxiZymes 2014

• Year: 2014 -  Understanding the inhibition mechanism of chlorite dismutase from the nitrite-oxidizing bacterium Candidatus Nitrospira defluvii

  Autoren: Hofbauer, S; Gruber, C; Schaffner, I; Pirker, KF; Jakopitsch, C; Sundermann, A; Oostenbrink, C; Furtmuller, PG; Obinger, C

  Event: 12th European Biological Inorganic Chemistry Conference EuroBIC 2014

• Year: 2014 -  Mechanism of reaction of chlorite with mammalian peroxidases

  Autoren: Jakopitsch, C; Pirker, KF; Flemmig, J; Hofbauer, S; Schlorke, D; Furtmuller, PG; Arnhold, J; Obinger, C

  Event: 12th European Biological Inorganic Chemistry Conference EuroBIC 2014

• Year: 2014 -  Interactions of hydrogen sulfide with human myeloperoxidase

  Autoren: Pirker, K.F., Pálinkás, Z., Furtmüller, P.G., Nagy, A., Jakopitsch, C., Obinger, C., Nagy, P.

  Event: OxiZymes 2014

• Year: 2014 -  Mechanism of inhibition of chlorite dismutase

  Autoren: Hofbauer, S., Schaffner, I., Gruber, C., Pirker, K.F., Jakopitsch, C., Sündermann, A., Oostenbrink, C., Furtmüller, P.G., Obinger, C.

  Event: OxiZymes 2014

• Year: 2014 -  Investigating the relation between structure and reaction mechanism of eukaryotic catalase-peroxidase

  Autoren: Gasselhuber, B; Nicolussi, A; Carpena, X; Zamocky, M; Jakopitsch, C; Furtmuller, PG; Fita, I; Obinger, C

  Event: 12th European Biological Inorganic Chemistry Conference EuroBIC 2014

• Year: 2014 -  Interactions of hydrogen sulfide with human myeloperoxidase.

  Autoren: Pirker, KF; Palinkás, Z; Furtmüller, PG; Nagy, A; Jakopitsch, C; Obinger, C; Nagy, P

  Event: Gordon Research Conference "Oxygen Radicals"

• Year: 2012 -  Human peroxidasin 1 – Phylogeny and preliminary characterization of a peculiar multidomain protein

  Autoren: Soudi, M., Zamocky, M., Jakopitsch, C., Furtmüller, P.G., and Obinger, C.

  Event: 9th International Conference on Protein Stability 2012 - From molecular level to market applications

• Year: 2012 -  Reaction of heme peroxidases with chlorite

  Autoren: Jakopitsch, C. Furtmüller, P.G. & Obinger, C.

  Event: OxiZymes 2012

• Year: 2012 -  The peroxidase-cyclooxygenase superfamily - phylogeny, structure and function

  Autoren: Obinger, C. Soudi, M. Auer, M. Zamocky, M. Jakopitsch C. and Furtmüller P.G.

  Event: OxiZymes 2012

• Year: 2012 -  Human peroxidasin 1 - phylogenetic analysis and characterization of a perculiar multidomain protein

  Autoren: Soudi, M. Zamocky, M. Jakopitsch., C. Delporte, C. Van Antwerpen, P. Furtmüller, P.G. & Obinger, C.

  Event: OxiZymes 2012

• Year: 2011 -  Modulation of heme reactivity of peroxidases by autocatalytic posttranslational modifications

  Autoren: Obinger, C., Stampler, J., Vlasits, J., Furtmüller, P. G., Smulevich, G., Battistuzzi, G.

  Event: International Conference on Bioinorganic Chemistry ICBIC-15 2011

• Year: 2010 -  From chemistry of bifunctional catalase-peroxidases towards molecular evolution of the peroxidase-catalase superfamily

  Autoren: Zamocky, M., Motz, M., Furtmüller, P. G., Vlasits, J., Jakopitsch, C., Obinger, C.

  Event: 5th Central European Conference on Chemistry meets biology

• Year: 2010 -  Mechanism of hydrogen peroxide oxidation in catalase-peroxidases

  Autoren: Jakopitsch, C., Vlasits, J., Obinger, C.

  Event: 5th Central European Conference on Chemistry meets biology

• Year: 2010 -  Mechanisms of catalase activity of heme peroxidases: from pseudo-catalatic activity in monofunctional peroxidases to high catalase activity in bifunctional catalase-peroxidases

  Autoren: Vlasits, J., Jakopitsch, C., Motz, M., Zamocky, M., Furtmüller, P.G., Obinger, C.

  Event: OxyZymes & 9th International Meeting on Peroxidases 2010

• Year: 2008 -  The peroxidase-cyclooxygenase superfamily

  Autoren: Obinger, C., Jakopitsch, C., Furtmüller, P.G., Zamocky, M.

  Event: 26th Congress of the Federation of European Societies of Plant Biology FESPB 2008 tohether with 11th annual international meeting for experimental moss research and 8th International Peroxidase Symposium, Peroxidase 2008

• Year: 2007 -  Evolutionary history of human peroxidases

  Autoren: Zamocky, M., Dunand, C., Furtmüller, P.G., Jakopitsch, C., Obinger, C.

  Event: 5th International Conference on Human Peroxidases 2007

• Year: 2007 -  Fungal catalase-peroxidases - a novel group of bifunctional oxidoreductases

  Autoren: Zamocky, M., Jakopitsch, C., Vlasits, J., Obinger, C.

  Event: 13th International Conference on Bioinorganic Chemistry ICBIC-13, 2007

• Year: 2007 -  Looking for peroxidase substrates and binding site(s) in bifunctional catalase-peroxidase

  Autoren: Vlasits, J., Zamocky, M., Jakopitsch, C., Obinger, C.

  Event: 13th International Conference on Bioinorganic Chemistry ICBIC-13, 2007

• Year: 2007 -  Redox thermodynamic of the Fe3+/Fe2+ couple in wild-type and mutated heme peroxidases

  Autoren: Battistuzzi, G., Bellei, M., Jakopitsch, C., Vlasits, J., Furtmüller, P.G., Sola, M., Obinger, C.

  Event: 13th International Conference on Bioinorganic Chemistry ICBIC-13, 2007

• Year: 2007 -  Chlorite as oxidant and reductant of heme peroxidases: a mechanistic study

  Autoren: Furtmüller, P.G., Jakopitsch, C., Spalteholz, H., Arnhold, J., Obinger, C.

  Event: 13th International Conference on Bioinorganic Chemistry ICBIC-13, 2007

• Year: 2006 -  Probing the reaction of three distinct catalase-peroxidases with peroxides

  Autoren: Jakopitsch, C., Wiseman, B., Vlasits, J., Obinger, C.

  Event: Peroxidase Meeting 2006

• Year: 2006 -  Identification of the unique site (Trp106) for the formation of the [Fe(IV)=O Trp.] intermediate in Synechocystis PCC6803 KatG and the (distal heme side) extended H-bonding network with a crucial role in catalase activity vy using multifrequency (9-285 GHz) EPR spectroscopy

  Autoren: Jakopitsch, C., Obinger, C., Un, S., Ivancich, A.

  Event: 8th European Biological Inorganic Chemistry Conference EuroBIC 2006

• Year: 2006 -  Trapping the spectral features of the redox intermediates in the catalatic cycle of catalase-peroxidase

  Autoren: Jakopitsch, C., Vlasits, J., Obinger, C.

  Event: 8th European Biological Inorganic Chemistry Conference EuroBIC 2006

• Year: 2006 -  Investigation of the catalytic mechanism of Synechocystis catalase-peroxidase with doubly O18-labeled hydrogen peroxide

  Autoren: Vlasits, J., Jakopitsch, C., Holubar, P., Obinger, C.

  Event: 8th European Biological Inorganic Chemistry Conference EuroBIC 2006

• Year: 2006 -  Redox thermodynamics of the Fe(III)/Fe(II) couple in wild-type heme peroxidases and in their CN-adducts

  Autoren: Bellei, M., Jakopitsch, C., Battistuzzi, G., Sola, M., Obinger, C.

  Event: Peroxidase Meeting 2006

• Year: 2006 -  The catalatic activity of monofunctional catalases and bifunctional catalase-peroxidases follows different mechanisms

  Autoren: Obinger, C., Vlasits, J., Jakopitsch, C.

  Event: 8th European Biological Inorganic Chemistry Conference EuroBIC 2006

• Year: 2006 -  Structure and function of peroxidases from the lactoperoxidase superfamily

  Autoren: Obinger, C., Zederbauer, M., Stampler, J., Jakopitsch, C., Furtmüller, P. G.

  Event: Peroxidase Meeting 2006

• Year: 2006 -  Detoxification of hydrogen peroxide in cyanobacteria

  Autoren: Bernroitner, M., Jakopitsch, C., Obinger, C.

  Event: Peroxidase Meeting 2006

• Year: 2005 -  The role in the stability of the heme architecture of selected catalase-peroxidase mutants. An overview of a spectroscopic study.

  Autoren: Droghetti, E., Jakopitsch, C., Obinger, C., Smulevich, G

  Event: COST D-21 Workshop on Metalloproteins

• Year: 2005 -  Probing the role of the peculiar Trp-Tyr-Met adduct in the heme pocket of bifunctional catalase-peroxidases

  Autoren: Jakopitsch, C., Vlasits, J., Ivancich, A., Obinger, C.

  Event: Life Sciences 2005, Joint Annual Meeting of ÖGBM, ÖGGGT, ÖGBT and ANGT

• Year: 2005 -  Mechanism of reaction of human peroxidases with nitrite and peroxynitrite.

  Autoren: Obinger, C., Furtmüller, P.G., Jantschko, W., Zederbauer, M., Jakopitsch, C., Herold, S., Koppenol, W.H.

  Event: COST D-21 Workshop on Metalloproteins

• Year: 2005 -  Spectral and kinetic studies on redox intermediates in heme peroxidases from both superfamilies

  Autoren: Obinger, C., Furtmüller, P.G., Zederbauer, M., Jakopitsch, C.

  Event: First European Conference on Chemistry for Life Sciences

• Year: 2005 -  The role of selected residues in the heme architecture of catalase-peroxidases

  Autoren: Droghetti, E., Jakopitsch, C., Obinger, C., Smulevich, G.

  Event: The VII Conference on Plant Peroxidases

• Year: 2005 -  The role of the unusual crosslinked distal site Trp-Tyr-Met adduct in catalysis of bifunctional catalase-peroxidase

  Autoren: Jakopitsch, C., Vlasits, J., Ivancich, A., Obinger, C.,

  Event: 1st European Conference on Chemistry for Life Sciences 2005

• Year: 2004 -  Redox Intermediates of human heme peroxidases: a comparative mutational and kinetic study .

  Autoren: Furtmüller, P. G., Jantschko, W., Zederbauer, M., Jakopitsch, C., Arnhold, J., Obinger, C.

  Event: 2nd European Conference on Chemistry towards Biology 2004

• Year: 2004 -  Kinetics of interconversion of redox intermediates of lactoperoxidase, eosinophil peroxidase and myeloperoxidase

  Autoren: Obinger, C., Jantschko, W., Zederbauer, M., Jakopitsch, C., Furtmüller, P. G.

  Event: 4th International Peroxidase Meeting 2004

• Year: 2004 -  Towards understanding the catalatic activity of peroxidases and catalases?

  Autoren: Jakopitsch, C., Schmuckenschlager, F., Zehner, F., Wanasinghe, A., Furtmüller, P. G., Obinger, C.

  Event: COST Chemistry Action D21

• Year: 2004 -  Reactivity of ferrous heme peroxidases from both superfamilies with hydrogen peroxide and molecular oxygen

  Autoren: Jantschko, W., Furtmüller, P. G., Zederbauer, M., Jakopitsch, C., Obinger, C.

  Event: COST Chemistry Action D21

• Year: 2004 -  Insights into catalase-peroxidase by electronic absorption, resonance Raman spectroscopy, and site-directed mutagenesis

  Autoren: Smulevich, G., Santoni, E., Jakopitsch, C., Obinger, C.

  Event: 3rd International Conference on Porphyrins and Phthalocyanines (ICPP-3) 2004

• Year: 2003 -  Comparison between catalase-peroxidase and cytochrom c peroxidase: A resonance raman study

  Autoren: Santoni, E., Jakopitsch, C., Obinger, C., and Smulevich, G.

  Event: Metalloenzymes and Chemical Biometics 2003

• Year: 2003 -  Engineering catalase-peroxidases: The structural basis of the activity of catalase-peroxidases.

  Autoren: Petutschnig, G., Jakopitsch, C., Auer, M., Rüker, F., Furtmüller, P. G., and Obinger, C.

  Event: Eigth International Summer School on Biophysics

• Year: 2003 -  Do we really understand the catalatic reactivity?

  Autoren: Jakopitsch, C; Petutschnig, G; Zehner, F; Ruker, F; Furtmuller, PG; Obinger, C

  Event: Plant Stress, Reactive Oxygen and Antioxidants

• Year: 2003 -  Identification of the radical intermediates formed by the catalase-peroxidase of Synechocystis PCC6803: A multifrequency EPR spectroscopy study combined with isotope labelling and site directed mutagenese

  Autoren: Ivancich, A., Jakopitsch, C., and Obinger, C.

  Event: Metalloenzymes and Chemical Biometics 2003

• Year: 2002 -  Understanding the Heme Cavity of Catalase-Peroxidase via Site-Directed Mutagenesis and Resonance Raman Spectroscopy

  Autoren: Smulevich, G., Santoni, E., Heering, H. A., Indiani, C., Jakopitsch, C., Regelsberger, G., and Obinger, C.

  Event: 6th European Biological Inorganic Chemistry Conference EuroBIC 2002

• Binding of peroxides and inhibitors to the active site of catalase-peroxidases.

  Autoren: Jakopitsch, C., Regelsberger, G., Rüker, F., Peschek, G.A., Obinger, C.

• Probing active site residues of catalase-peroxidases.

  Autoren: Jakopitsch, C., Regelsberger, G., Rüker, F., Peschek , G.A., Obinger, C.

• Hydroperoxidases in oxygenic phototrophic prokaryotes- comparison to plant chloroplasts

  Autoren: Regelsberger, G., Jakopitsch, C., Rücker, F., Peschek, G.A., Obinger, C.

• Catalase versus peroxidase activity. Towards understanding the bifunctional activity of catalase-peroxidases.

  Autoren: Regelsberger, G., Jakopitsch, C., Rüker, F., Loewen, P., Peschek, G. A., Obinger, C.

• Manipulating the distal asparagine-histidine couple in catalase-peroxidase.

  Autoren: Jakopitsch, C., Regelsberger, G., Rücker, F., Peschek, G.A., Obinger, C.

• Catalase versus peroxidase activity. Towards understanding the bifunctional activity of catalase-peroxidases.

  Autoren: Regelsberger, G., Jakopitsch, C., Rüker, F., Peschek, G.A., Switala, J., Loewen, P., Obinger, C.

• Molecular engineering of catalase-peroxidases.

  Autoren: Jakopitsch, C., Regelsberger, G., Rüker, F., Peschek, G.A., Obinger, C.

• Binding of peroxides and inhibitors to the active site of catalase-peroxidases.

  Autoren: Jakopitsch, C., Regelsberger, G., Rüker, F., Peschek, G.A., Obinger, C.

• The molecular and functional peculiarities of class I peroxidases.

  Autoren: Obinger, C., Regelsberger, G., Jakopitsch, C., Peschek, G.A., Rüker, F.

• The catalatic acitivity of catalase-peroxidases.

  Autoren: Jakopitsch, C., Regelsberger, G., Rüker, F., Peschek, G.A., Obinger, C.