Clemens Grünwald-Gruber
Dipl.-Ing. Dr.nat.techn. Clemens Grünwald-Gruber
BOKU Core Facilities
Institute of Biochemistry (DCH/BC)
Location Muthgasse 11, 1190 Wien
Email clemens.gruber@boku.ac.at
Tel: +43 1 47654-35052
Projects
0 Projects found.
Publications
Knowledge Transfer to Society
Media
Lectures
Year: 2023 - First crystal structure of eosinophil peroxidase reveals suptile distinctions in the active site architecture and processing
Autoren: Pfanzagl, V; Leitgeb, U; Grünwald-Gruber, C; Furtmüller, P.G; Obinger, C;
Event: 12th International Human Peroxidase Meeting
Year: 2019 - Analysis of bacterial arabinosyl transferase reaction products of Kdo2-lipid A by LC-ESI-MS
Autoren: Grünwald-Gruber, C; Olagnon, C; Julia Monjaras, F; Kosma, P; Altmann F
Event: APMRS 2019
Year: 2019 - Investigation of 4-amino-4-deoxy-L-arabinose transferases from Gram-negative bacteria involved in antibiotic resistance
Autoren: Olagnon, C; Feras, JM; Grünwald-Gruber, C; Altmann, F; Kerner, L; Valvano, MA, Kosma, P.
Event: Eurocarb 20 2019
Year: 2019 - Subcellular proteome atlas of the yeast Komagataella phaffii
Autoren: Valli, M; Grillitsch, KH; Grünwald-Gruber, C; Tatto, NE; Hrobath, B; Klug, L; Ivashov, V; Hauzmayer, S; Koller, M; Leisch, F; Gasser, B; Graf AB; Altmann, F; Daum, G; Mattanovich D
Event: PYFF7 2019
Year: 2019 - A conserved glycosyltransferase from the general protein O-glycosylation pathway of Bacteroidetes
Autoren: Braun*, M., B. Janesch, M. B. Tomek, D. Maresch, C. Grünwald-Gruber, M. Blaukopf, P. Kosma, F. Altmann, C. Schäffer
Event: Soc. for Glycobiology Annual Meeting
Year: 2019 - Analysis of intracellular interaction partners of recombinant proteins in Pichia pastoris
Autoren: Schmelzer, B; Grünwald-Gruber, C; Altmann, F; Gasser, B; Mattanovich, D
Event: RPP10 2019
Year: 2019 - CRISPR-based targeted epigenetic glyco-engineering in CHO cell
Autoren: Marx, N, Grünwald-Gruber, C; Dhiman, H; Nguyen Ngoc, L; Bydlinski, N; Hernandez Lopez, I; Klanert, G; Borth, N
Event: 26th European Society for Animal Cell Technology ESACT Meeting 2019
Year: 2018 - Characterization of O-glycosylation in recombinant Pichia pastoris
Autoren: Radoman, B; Grünwald-Gruber, C; Rebnegger, C; Schmelzer, B; Altmann, F; Mattanovich, D; Gasser, B
Event: EMBO Workshop - Enzymes, biocatalysis ans chemical biology: The new frontiers
Year: 2018 - Characterizing vacuolar protein sorting pathways for enhanced protein secretion in the yeast Pichia pastoris (Komagatella spp)
Autoren: Marsalek, L; Puxbaum, V; Gruber-Grünwald, C; Altmann, F; Mattanovich, D; Gasser, B
Event: Non-conventional yeasts: from basic research to application 2018
Year: 2018 - Analysis of mouse brain N-glycans by (PGC-)LC-ESI-MS using isotopically labeled standards
Autoren: Grünwald-Gruber, C; Thader, A; Urteil, J; Maresch, D; Altmann, F;
Event: 22nd International Mass Spectrometry Conference IMSC 2018
Year: 2018 - Engineering vacuolar sorting pathways for efficient secretion of recombinant proteins
Autoren: Marsalek, L; Gruber, C; Altmann, F; Mattanovich, D; Puxbaum, V; Gasser, B;
Event: Microbial Engineering
Year: 2018 - Characterization of O-glycans in recombinant proteins produces in Pichia pastoris,
Autoren: Radoman, B; Grünwald-Gruber, C; Schmelzer, B; Gasser, B; Mattanovich, D; Altmann, F
Event: EMBO Practical Course - Characterization of post translational modifications in cellular signaling
Year: 2018 - Multiplexed isotope labeled standards for isomeric analysis of N-glycans
Autoren: Maresch, D; Grünwald-Gruber, C; Thader, A; Altmann, F
Event: 22nd International Mass Spectrometry Conference IMSC 2018
Year: 2017 - Beyond the golden standard – N-glycan analysis with ultimate power of isomer discrimination and its application to biological questions.
Autoren: Altmann, F; Grünwald-Gruber, C; Maresch, D; Thader, A
Event: 14th Bratislava Symposium on Saccharides BSS 2017
Year: 2017 - Simultaneous identification and relative quantification of 16 putative allergens from tomato
Autoren: Mócsai, RT; Grünwald-Gruber, C; Milotay, P; Gasztonyi, M; Tömösközi-Farkas, R
Event: 19th EuroFoodChem Conference 2017
Year: 2017 - Determination of true ratios of different N-glycan structures in electrospray ionization-mass spectrometry
Autoren: Grünwald-Gruber, C: Thader, A; Maresch, D; Dalik, T; Altmann, F
Event: Austrian Proteomics and Metabolomics Research Symposium APRS 2017
Year: 2017 - Characterizing vacuolar protein sorting pathways in the yeast Pichia pastoris
Autoren: Marsalek, L; Gruber, C; Altmann, F; Mattanovich, D; Puxbaum, V; Gasser, B;
Event: EMBO Workshop
Year: 2017 - Identification of intracellular interaction partners of recombinant proteins
Autoren: Schmelzer, B; Grünwald-Gruber, C; Altmann, F; Gasser, B; Mattanovich, D;
Event: European Summit of Industrial Biotechnology ESIB 2017
Year: 2017 - Characterizing Vacuolar Protein Sorting Pathways in the Yeast Pichia Pastoris
Autoren: Marsalek, L; Grünwald-Gruber, C; Altmann, F; Mattanovich, D; Puxbaum, V; Gasser, B;
Event: European Summit of Industrial Biotechnology ESIB 2017
Year: 2017 - Determination of true ratios of different N-glycan structures in electrospray ionization-mass spectrometry
Autoren: Grünwald-Gruber, C; Thader, A; Maresch, D; Dalik, T; Altmann, F
Event: 28th MassSpec Forum Vienna 2017
Year: 2017 - Characterizing vacuolar protein sorting pathways in the yeast Pichia pastoris
Autoren: Gasser, B; Marsalek, L; Gruber, C; Altmann, F; Mattanovich, D; Puxbaum, V;
Event: 28th International Conference on Yeast Genetics and Molecular Biology ICYGMB 2017
Year: 2017 - Site-specific N-glycosylation analysis of human IgA isotypes produced in glyco-engineered plants by LC-ESI-MS
Autoren: Maresch, D; Göritzer, K; Grünwald-Gruber, C; Strasser, R; Altmann, F
Event: 16th Human Proteome Organization World Congress 2017
Year: 2017 - Portraying the sweet and the dark sides of a protein
Autoren: Grünwald-Gruber, C; Maresch, D; Altmann, F;
Event: European Summit of Industrial Biotechnology ESIB 2017
Year: 2017 - Characterization of O-glycans in recombinant proteins produced in Pichia pastoris
Autoren: Radoman, B; Grünwald-Gruber, C; Schmelzer, B; Gasser, B; Altmann, F; Mattanovich, D;
Event: 9th International Conference on Recombinant Protein Production RPP9 2017
Year: 2017 - Characterization of O-glycans in recombinant proteins produced in Pichia pastoris
Autoren: Radoman, B; Grünwald-Gruber, C; Schmelzer, B; Gasser, B; Altmann, F; Mattanovich, D;
Event: European Summit of Industrial Biotechnology ESIB 2017
Year: 2017 - Production of recombinant glycosylated polymeric IgM antibodies in CHO cells
Autoren: Hennicke, J; Grünwald-Gruber, C; Reinhart, D; Altmann, F; Kunert, R
Event: GlycoBioTec 2017
Year: 2017 - Analysis of human brain N-glycans by (PGC-)LC-ESI-MS using isotopically labeled standards
Autoren: Grünwald-Gruber, C; Thader, A; Maresch, D; Hirtler, L; Altmann, F
Event: 16th Human Proteome Organization World Congress 2017
Year: 2017 - Identification of intracellular interaction partners of recombinant proteins
Autoren: Schmelzer, B; Grünwald-Gruber, C; Altmann, F; Gasser, B; Mattanovich, D;
Event: 9th International Conference on Recombinant Protein Production RPP9 2017
Year: 2016 - Identification of intracellular interaction partners of recombinant proteins
Autoren: Schmelzer, B; Grünwald-Gruber, C; Altmann, F; Gasser, B; Mattanovich, D;
Event: ESIB – European Summit of Industrial Biotechnology
Year: 2016 - Systems-level organization of yeast methylotrophic lifestyle: The xylulose-monophosphate cycle of methanol assimilation utilizes a duplicated methanol inducible enzyme set and is entirely localized to peroxisomes
Autoren: Rußmayer, H; Buchetics, M; Gruber, C; Valli, M; Grillitsch, K; Modarres, G; Drexler, H; Steiger, M; Daum, G; Graf, A; Altmann, F; Hann, S; Sauer, M; Mattanovich, D; Gasser, B;
Event: PYFF6 - 6th Conference on Physiology of Yeasts and Filamentous Fungi
Year: 2016 - Methanol metabolism revisited: The xylulose-monophosphate cycle of methanol assimilation utilizes a duplicated methanol inducible enzyme set and is entirely localized to peroxisomes
Autoren: Rußmayer, H; Buchetics, M; Gruber, C; Valli, M; Grillitsch, K; Modarres, G; Drexler, H; Steiger, M; Daum, G; Graf, A; Altmann, F; Hann, S; Sauer, M; Mattanovich, D; Gasser, B;
Event: Pichia 2016
Year: 2016 - Dioxygen evolution by chlorite dismutase depends on co-ordination of transiently produced hypochlorite to an oxoiron(IV) intermediate
Autoren: Hofbauer, S., Grünwald-Gruber, C., Schaffner, I., Sündermann, A., Jakopitsch, C., Oostenbrink, C., Djinovic-Carugo, K., Furtmüller, P.G., Obinger, C.
Event: 79th Harden Conference on Oxygen Evolution and Reduction
Year: 2016 - Curation of the Pichia pastoris genome annotation by integration of RNA-Seq and proteomic data
Autoren: Valli, M; Peymann, A; Gruber, C; Tatto, N; Mattanovich, D; Gasser, B; Graf, A;
Event: Pichia 2016
Year: 2016 - Secretome diversity of Pichia pastoris in the presence of different carbon sources
Autoren: Hohlweg, J; Gruber, C; Altmann, F; Valli, M; Mattanovich, D; Gasser, B;
Event: ESIB 2016
Year: 2016 - Curation of the Pichia pastoris (Komagatella phaffi) genome annotation by integration of RNA-Seq and proteomic data
Autoren: Valli, M; Tatto, N; Peymann, A; Gruber, C; Landes, N; Ekker, H; Thallinger, G; Mattanovich, D; Gasser, B; Graf, A
Event: ESIB 2016
Year: 2016 - Analysis of O-linked glycans of recombinant Art v 1 by LC-ESI-MS-ETD
Autoren: Grünwald-Gruber, C: Svehla, E; Windwarder, M; Thader, A; Maresch, D; Altmann, F
Event: BSPR meeting 2016
Year: 2015 - Outer membrane vesicles of Tannerella forsythia: Biogenesis, composition, and virulence
Autoren: Friedrich, V., C. Gruber, I. Nimeth, S. Pabinger, F. Altmann, P. Messner, O. Andrukhov, C. Schäffer*
Event: 2nd International Conference on Porphyromonas gingivalis and Related Species in Oral and Systemic Diseases 2015
Year: 2015 - Secretome diversity of Pichia Pastoris in the presence of different carbon sources
Autoren: Hohlweg, J; Gruber, C; Altmann, F; Valli, M; Mattanovich, D; Gasser, B
Event: 27th International Conference on Yeast Genetics and Molecular Biology ICYGMB 2015
Year: 2015 - The Pichia pastoris secretome in fed-batch cultivations is carbon source independent
Autoren: Hohlweg, Jonas, Gruber, Clemens, Altmann, Friedrich, Valli, Minoska, Mattanovich, Diethard, Gasser, Brigitte
Event: ACIB Science Days 2015
Year: 2015 - The xylulose-monophosphate cycle of methanol assimilation utilizes a duplicated methanol inducible enzyme set and is entirely localized to peroxisomes
Autoren: Gasser, B; Russmayer, H; Buchetics, M; Gruber, C; Valli, M; Grillitsch, K; Modarres, G; Drexler, H; Steiger, M; Daum, G; Graf, AB; Altmann, F; Hann, S; Sauer, M; Mattanovich, D
Event: 27th International Conference on Yeast Genetics and Molecular Biology ICYGMB 2015
Year: 2014 - Investigation of a prokaryotic peroxidase with a covalently bound heme b from the cyanobacterium Lyngbya sp PCC 8106
Autoren: Nicolussi, A; Auer, M; Schutz, G; Gruber, C; Pirker, K; Zamocky, M; Furtmuller, PG; Obinger, C
Event: 12th European Biological Inorganic Chemistry Conference EuroBIC 2014
Year: 2014 - Multistep processing of the secretion leader of the CRISP family member Epx1 in Pichia pastoris and implications on protein localization
Autoren: Heiss, Silvia; Puxbaum, Verena; Gruber, Clemens; Altmann, Friedrich; Mattanovich, Diethard and Gasser, Brigitte
Event: ACIB-UAB Workshop - Systems Biology for Metabolic Engineering
Year: 2014 - Proteomic study of Pichia pastoris cell compartments
Autoren: Gruber, C; Grillitsch, K-H; Klug, L; Valli, M; Gasser, B; Mattanovich, D; Daum, G; Altmann, F
Event: APRS 2014
Year: 2014 - Influence of recombinant protein expression on the proteome of Pichia pastoris
Autoren: Gruber, Clemens; Landes, Nils; Valli, Minoska; Modarres, Gerda; Gasser, Brigitte; Graf, Alexandra; Altmann, Friedrich; Mattanovich, Diethard
Event: 6th ÖGMBT Annual Meeting 2014 - Life Sciences meet Entrepreneurship
Year: 2014 - Proteomic study of Pichia pastoris cell compartments
Autoren: Gruber, C; Landes, N; Valli, M; Modarres, G; Gasser, B; Graf, AB; Altmann, F; Mattanovich, D
Event: 6th ÖGMBT Annual Meeting 2014 - Life Sciences meet Entrepreneurship
Year: 2014 - The role of the covalent heme to protein bond in the formation and reactivity of redox intermediates of a bacterial peroxidase with high homology to human peroxidases
Autoren: Auer, M., Nicolussi, A., Schütz, G. Gruber, C., Bellei, M., Battistuzzi, G., Furtmüller, P.G., Obinger, C
Event: OxiZymes 2014
Year: 2014 - Methanol induced changes on the transcriptome, proteome, metabolome and fluxome of Pichia pastoris
Autoren: Rußmayer, Hannes; Buchetics, Markus; Graf, Alexandra; Valli, Minoska; Gruber, Clemens; Modarres, Gerda; Altmann, Friedrich; Guerrasio, Raffaelle; Klavins, Kristaps; Neubauer, Stefan; Steiger, Matthias; Chalabi, Ali Al; Krebiehl, Guido; Sonntag, Denise; Haberhauer-Troyer, Christina; Köllensperger, Gunda; Hann, Stephan; Sauer, Michael; Gasser, Brigitte; Mattanovich, Diethard
Event: ACIB-UAB Workshop - Systems Biology for Metabolic Engineering
Year: 2014 - Methanol induced changes on the transcriptome, proteome, metabolome and fluxome of Pichia pastoris
Autoren: Rußmayer, Hannes; Buchetics, Markus; Graf, Alexandra; Valli, Minoska; Gruber, Clemens; Modarres, Gerda; Altmann, Friedrich; Guerrasio, Raffaelle; Klavins, Kristaps; Neubauer, Stefan; Steiger, Matthias; Chalabi, Ali Al; Krebiehl, Guido; Sonntag, Denise; Haberhauer-Troyer, Christina; Köllensperger, Gunda; Hann, Steph
Event: ACIB-UAB Workshop - Systems Biology for Metabolic Engineering
Year: 2014 - Mechanism of inhibition of chlorite dismutase
Autoren: Hofbauer, S., Schaffner, I., Gruber, C., Pirker, K.F., Jakopitsch, C., Sündermann, A., Oostenbrink, C., Furtmüller, P.G., Obinger, C.
Event: OxiZymes 2014
Year: 2014 - Understanding the inhibition mechanism of chlorite dismutase from the nitrite-oxidizing bacterium Candidatus Nitrospira defluvii
Autoren: Hofbauer, S; Gruber, C; Schaffner, I; Pirker, KF; Jakopitsch, C; Sundermann, A; Oostenbrink, C; Furtmuller, PG; Obinger, C
Event: 12th European Biological Inorganic Chemistry Conference EuroBIC 2014
Year: 2014 - Multistep processing of the secretion leader of the CRISP family member Epx1 in Pichia pastoris and implications on protein localization
Autoren: Heiss, Silvia; Puxbaum, Verena; Gruber, Clemens; Altmann, Friedrich; Mattanovich, Diethard and Gasser, Brigitte
Event: EMBO Workshop Protein and lipid function in secretion and endocytosis
Year: 2014 - Cross-species comparison of recombinant protein secretion in CHO cells and Pichia pastoris
Autoren: Landes, Nils; Maccani, Andreas; Leitner, Christian; Maurer, Michael; Graf, Alexandra; Valli, Minoska; Gruber, Clemens; Modarres, Gerda; Altmann, Friedrich; Gasser, Brigitte; Ernst, Wolfgang; Kunert, Renate; Mattanovich, Diethard
Event: ECB16 2014
Year: 2013 - Understanding highly stable chlorite dismutase form nitrate-oxidizing bacterium Candidatus “Nitrospira defluvii”
Autoren: Hofbauer, S., Gruber, C., Pirker, K. F., Schaffner, I., Hagmüller, A., Gysel, K., Mlynek, G., Kostan, J., Bellei, M., Daims, H., Djinovic-Carugo, K. Battistuzzi, G., Furtmüller, P.G. and Obinger, C
Event: International Conference on Bioinorganic Chemistry ICBIC-16 2013
Year: 2013 - New highly stable chlorinating bacterial peroxidase with autocatalytically formed covalent heme to protein bonds
Autoren: Furtmuller, PG; Auer, M; Gruber, C; Pirker, K; Krioss, D; Hofbauer, S; Soudi, M; Obinger, C; Zamocky, M; Bellei, M; Battistuzzi, G
Event: International Conference on Bioinorganic Chemistry ICBIC-16 2013
Year: 2013 - Multistep processing of the secretion leader of the CRISP family member Epx1 in Pichia pastoris and implications on protein localization
Autoren: Gasser, B; Heiss, S; Puxbaum, V; Gruber, C; Altmann, F; Mattanovich, D
Event: 26th International Conference on Yeast Genetics and Molecular Biology 2013
Year: 2013 - Understanding Chlorite Dismutase from Candidatus Nitrospira defluvii
Autoren: Hofbauer, S; Gruber, C; Pirker, KF; Schaffner, I; Furtmuller, PG; Obinger, C; Hagmuller, A; Gysel, K; Mlynek, G; Kostan, J; Djinovic-Carugo, K; Bellei, M; Battistuzzi, G; Daims, H
Event: International Conference on Bioinorganic Chemistry ICBIC-16 2013
Year: 2013 - New highly stable chlorinating bacterial peroxidase with autocatalytically formed covalent heme to protein bonds
Autoren: Auer, M. Gruber, C. Bellei, M., Pirker, K., Kroiß, D., Zamocky, M. Teufer, A. S., Soudi, M., Battistuzzi, G., Obinger, C. and Furtmüller P. G.
Event: International Conference on Bioinorganic Chemistry ICBIC-16 2013
Year: 2013 - Influence of carbon source on the Pichia pastoris proteome
Autoren: C. Gruber1)2), M. Buchetics1)3), G. Modarres1)3),B. Gasser1)3), A.B.Graf1)4), F. Altmann1)2)and D. Mattanovich1)3) Gruber, C; Buchetics, M; Modarres, G; Gasser, B; Graf, AB; Altmann, F; Mattanovich, M
Event: 11th Austrian Proteomic Research Symposium
Year: 2012 - Bacterial heme enzyme of high structural and funtional homology with mammaian peroxidases -characterization of the first representative of a new protein family
Autoren: Auer, M. Kroiß, D. Gruber, C. Zamocky, M. Furtmüller, P.G. & Obinger, C.
Event: OxiZymes 2012
Year: 2012 - Human cathepsin O: glycosylation, processing and cellular activity
Autoren: Aufy, M; Porodko, A; Stadlmann, J; Gruber, C; Mach, L
Event: 13th International Symposium on Proteinases, Inhibitors and Biological Control 2012