Johannes Grillari

Research Focus

Johannes Grillari is director of the Ludwig Boltzmann Institute for Traumatology. The Research Center in cooperation with AUVA and associate Professor at the Dept. of Biotechnology at BOKU University Vienna. His research interest is on improving our understanding of the molecular and physiological changes that occur during cellular aging, their impact on organismal aging and tissue regeneration. His work has pioneered the role of miRNAs in cellular senescence, bone and skin regeneration, showing that extracellular vesicles and their cargo, especially their miRNA cargo are inhibitors of regeneration when from senescent cells, while they have therapeutic effects when coming from mesenchymal stroma cells. He was also instrumental in designing targeting EVs for regenerative medicine purposes. He has authored and co-authored more than 230 SCI publications and 15 patents. He is also co-founder of companies in the space of cellular senescence and extracellular vesicles.