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Research Focus

Johannes Grillari is director of the Ludwig Boltzmann Institute for Traumatology. The Research Center in cooperation with AUVA and associate Professor at the Dept. of Biotechnology at BOKU University Vienna. His research interest is on improving our understanding of the molecular and physiological changes that occur during cellular aging, their impact on organismal aging and tissue regeneration. His work has pioneered the role of miRNAs in cellular senescence, bone and skin regeneration, showing that extracellular vesicles and their cargo, especially their miRNA cargo are inhibitors of regeneration when from senescent cells, while they have therapeutic effects when coming from mesenchymal stroma cells. He was also instrumental in designing targeting EVs for regenerative medicine purposes. He has authored and co-authored more than 230 SCI publications and 15 patents. He is also co-founder of companies in the space of cellular senescence and extracellular vesicles.

free keywords cellular aging replicative senescence pre mRNA splicing Ubiquitin and proteasome tissue regeneration

 

Career

  • 2019 Director of the Ludwig Boltzmann Institute for experimental and clinical Truamatology
  • 2010 A2 Professorship
  • 2006 Venia docendi in Molecular Biology
  • 2005 Univ. Ass.
  • 2003 Visiting scientist at the Lamond Lab, University of Dundee
  • 2000 Group Leader of Aging Research at the IAM
  • 1999 PhD of University of Nat. Resources and Appl. Life Sciences
  • 1996 First level of the studies of business administration, WU Vienna
  • 1996 Diploma of Food- and Biotechnology

Awards

  • Year: 2012 Awards: Walter Doberauer Preis für Alternsforschung
  • Year: 2011 Awards: Best Presentation award, telomerase: a crystal ball for the future? Stockholm, Sweden
  • Year: 2006 Awards: Poster prize at the European conference on Aging "ECONAG 2006", November 27-30 2006, Innsbruck, Austria,
  • Year: 2004 Awards: Poster prize at the EMBO/Harden conference ”Ubiquitin and Proteasome system in health and disease” September 6-10 2004, Cirencester, UK

Projects

0 Projects found.

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    Publications

    Knowledge Transfer to Society

    Media

    Lectures

    • Year: 2023 -  Janus faced EVs - potential diagnostic and therapeutic uses in tissue regeneration

      Autoren: Grillari Johannes

      Event: Comparative Biomedicine Symposium 2023

    • Year: 2023 -  From cellular senescence to ‚young‘ companies

      Autoren: Grillari Johannes

      Event: Tissue Engineering and Regenerative Medicine International Society (TERMIS) European Chapter Meeting 2023

    • Year: 2023 -  From Cellular Senescence to an Extracellular Vesicle

      Autoren: Grillari Johannes

      Event: The International Society of BioProcess Technology

    • Year: 2023 -  Aging / Senescence

      Autoren: Grillari Johannes

      Event: SFB1506 Aging@Interfaces

    • Year: 2023 -  Seneszenz in Geweberegeneration

      Autoren: Grillari Johannes

      Event: 76. ÖGU Fortbildung “Verletzungen der Sehnen und Muskeln des Bewegungsapparates”

    • Year: 2022 -  Ribosome heterogeneity by rRNA methylation in skin cell senescence

      Autoren: Nagelreiter, F; Yang, G; Heissenberger, C; Gonskikh, Y; Polacek, N; Grillari, J; Kos, M; Schosserer, M

      Event: 2nd Euro Geroscience Conference 2022

    • Year: 2022 -  The role of protein synthesis and RNA modifications in cellular senescence

      Autoren: Nagelreiter, F; Yang, G; Heissenberger, C; Gonskikh, Y; Polacek, N; Kos, M; Grillari, J; Schosserer, M

      Event: Austrian Cluster for Tissue Regeneration Annual Meeting 2022

    • Year: 2022 -  From Cellular Senescence to Production of MSC derived EVs.

      Autoren: Grillari Johannes

      Event: Cluster Meeting - Extrazelluläre Vesikel in der Stammzellforschung

    • Year: 2022 -  Senescent cell derived extracellular vesicles and their miRNA cargo modulate cell fate decisions.

      Autoren: Grillari Johannes

      Event: Annual Meeting of the Spanish Network for Research on Cellular Senescence.

    • Year: 2022 -  From cellular senescence to tissue regeneration.

      Autoren: Grillari Johannes

      Event: Internationales Trauma Symposium, Ulm

    • Year: 2022 -  From EV biology to application.

      Autoren: Grillari Johannes

      Event: 27th European Society for Animal Cell Technology ESACT Meeting 2022

    • Year: 2022 -  The SASP and Its Control

      Autoren: Grillari Johannes

      Event: 17. Benjamin-von-Lipschütz-Symposium

    • Year: 2022 -  CD81 large extracellular loop as a novel alternative scaffold: laminin binding CD81 enhances specific uptake of extracellular vesicles

      Autoren: Wozniak-Knopp, G; Vogt, S; Stadlmayr, G; Stadlbauer, K; Bobbili, MR; Kjems, J; Rüker, F; Grillari, J

      Event: 9th BBBB International Conference on Pharmaceutical Sciences 2022

    • Year: 2021 -  From cellular senescence to cell based assays and RNA diagnostics. A journey.

      Autoren: Grillari, J

      Event: SLAS Europe 2021 Digital Conference & Exhibition

    • Year: 2021 -  Heterogenous ribosomes in human dermal fibroblast senescence

      Autoren: Nagelreiter, F; Yang, G; Heissenberger, C; Gonskikh, Y; Polacek, N; Grillari, J; Kos, M; Schosserer, M

      Event: Virtual 50th Anniversary ESDR Annual Meeting

    • Year: 2021 -  Biologie des Alterns.

      Autoren: Grillari J.

      Event: ÖAK Geriatrie Seminar

    • Year: 2021 -  Heterogenous ribosomes in human dermal fibroblast senescence

      Autoren: Nagelreiter, F; Yang, G; Heissenberger, C; Gonskikh, Y; Polacek, N; Grillari, J; Kos, M; Schosserer, M

      Event: The 8th Aging Research and Drug Discovery Meeting

    • Year: 2021 -  Telomerase immortalized cells as a scaleable production system for EVs.

      Autoren: Grillari, J

      Event: ISEV Infectious Diseases Meeting

    • Year: 2021 -  From aging research to diagnostic miRNA.

      Autoren: Grillari, J

      Event: 29th Annual Meeting European Orthopaedic Research Society

    • Year: 2021 -  Heterogenous ribosomes in human dermal fibroblast senescence

      Autoren: Nagelreiter, F; Yang, G; Heissenberger, C; Gonskikh, Y; Polacek, N; Grillari, J; Kos, M; Schosserer, M

      Event: Tissue Engineering and Regenerative Medicine International Society (TERMIS) 6th World Congress

    • Year: 2021 -  Heterogenous ribosomes in human dermal fibroblast senescence

      Autoren: Nagelreiter, F; Yang, G; Heissenberger, C; Gonskikh, Y; Polacek, N; Grillari, J; Kos, M; Schosserer, M

      Event: EMBL Conference 2021 - Protein Synthesis and Translational Control

    • Year: 2021 -  Exploring the role of the epitranscriptome in aging

      Autoren: Wagner, A; Grillari, J; Schosserer, M

      Event: RNA Biology forever - Vienna RNA Meeting 2021

    • Year: 2021 -  EV contained lipids and miRNAs are novel members of the SASP: From biomarkers to senolytics.

      Autoren: Grillari, J

      Event: 1st RESETageing Conference

    • Year: 2020 -  Nsun5 in ribosome function and mammalian healthy lifespan

      Autoren: Liendl, L; Heissenberger, C; Nagelreiter, F; Plasenzotti, R; Grillari, J; Schosserer, M

      Event: Cold Spring Harbor Meeting: "Mechanisms of Aging"

    • Year: 2020 -  Specialized ribosomes in human dermal fibroblast senescence

      Autoren: Nagelreiter, F; Yang, G; Liendl, L; Heissenberger, C; Gonskikh, Y; Polacek, N; Grillari, J; Kos, M; Schosserer, M

      Event: Cold Spring Harbor Meeting: "Mechanisms of Aging"

    • Year: 2020 -  Nsun5 modulates ribosome function and mammalian healthy lifespan

      Autoren: Liendl, L; Heissenberger, C; Plasenzotti, R; Grillari, J; Schosserer, M

      Event: 12th Annual ÖGMBT Meeting

    • Year: 2020 -  Specialized ribosomes in human dermal fibroblast senescence

      Autoren: Nagelreiter, F; Yang, G; Heissenberger, C; Gonskikh, Y; Polacek, N; Kos, M; Grillari, J; Schosserer, M

      Event: Keystone Symposia: Intra- and Intercellular Mechanisms of Aging

    • Year: 2020 -  The role of RNA methylations in biological aging

      Autoren: Wagner, A; Grillari, J; Schosserer, M

      Event: Cold Spring Harbor Meeting: "Translational Control"

    • Year: 2019 -  Senescent fibroblasts accumulate lysophospholipids with immunomodulatory properties

      Autoren: Narzt, M; Pils, V; Mildner, M; Nanic, L; Kremslehner, C; Wedel, S; Cavinato-Nascimento, M; Waidhofer-Soellner, P; Rubelj, I; Jansen-Duerr, P; Grillari, J; Gruber, F; Laemmermann, I

      Event: Society-for-Investigative-Dermatology (SID) Meeting

    • Year: 2019 -  Improving the stability of the large extracellular loop of human tetraspanin CD81

      Autoren: Stefan Vogt, Gerhard Stadlmayr, Katharina Stadlbauer, Florian Rüker, Johannes Grillari, Gordana Wozniak-Knopp

      Event: International Society of Extracellular Vesicles - Annual Meeting 2019

    • Year: 2019 -  Specialized ribosomes in human dermal fibroblast senescence

      Autoren: Nagelreiter, F; Yang, G; Heissenberger, C; Gonskikh, Y; Polacek, N; Grillari, J; Kos, M; Schosserer, M

      Event: 49th Annual Meeting of the European-Society-for-Dermatological-Research ESDR 2019

    • Year: 2019 -  Senolytic therapy – a promising strategy against age-related diseases and disorders

      Autoren: Lämmermann, I; Pils, V; Narzt, MS; Nanic, L; Rubelj, I; Wilmes, A; Jennings, P; Gruber, F; Grillari, J

      Event: Menopausenkongress 2019

    • Year: 2019 -  Novel Senolytics based on Arachidonic Acid Metabolism

      Autoren: Lämmermann, I; Pils, V; Narzt, MS; Nanic, L; Rubelj, I; Wilmes, A; Jennings, P; Gruber, F; Grillari, J

      Event: Undoing Aging 2019

    • Year: 2019 -  Novel Senolytics based on Arachidonic Acid Metabolism

      Autoren: Lämmermann, I; Pils, V; Narzt, MS; Nanic, L; Rubelj, I; Wilmes, A; Jennings, P; Gruber, F; Grillari, J

      Event: 10th Annual Alliance for Healthy Aging Conference 2019

    • Year: 2019 -  Senescent fibroblasts accumulate lysophospholipids with immunomodulatory properties

      Autoren: Narzt, M; Pils, V; Nagelreiter, IM; Mildner, M; Nanic, L; Rubelj, I; Kremslehner, C; Branco, A; Wedel, S; Cavinato-Nascimento, MA; Waidhofer-Sollner, P; Jansen-Durr, P; Grillari, J; Gruber, F; Lammermann, I

      Event: Annual Meeting of the Society-for-Free-Radical-Research- Europe (SFRRE) on Redox Homeostasis - From Signaling to Damage

    • Year: 2019 -  Loss of the ribosomal RNA methyltransferase NSUN5 impairs global protein synthesis and normal growth

      Autoren: Heissenberger, C; Nagelreiter, F; Gonskikh, Y; Liendl, L; Koš, M; Polacek, N; Grillari, J; Schosserer, M

      Event: Gordon Research Conference: "RNA Editing"

    • Year: 2019 -  Two specific m5C-modifications of ribosomal RNA distinctly modulate healthy lifespan and development

      Autoren: Heissenberger, C; Krammer, TL; Stocker, I; Rollins, JA; Nagelreiter, F; Grillari, J; Lafontaine, DLJ; Rogers, A; Schosserer, M

      Event: 11th ÖGMBT Annual Meeting 2019 - Inside the World of Biomolecules

    • Year: 2019 -  Altered MicroRNA Profile in Osteoporosis Caused by Impaired WNT Signaling.

      Autoren: Mäkitie, RE; Hackl, M; Niinimäki, R; Kakko, S; Grillari, J; Mäkitie, O;

      Event: 51st Conference of the European-Society-of-Human-Genetics (ESHG) in conjunction with the European Meeting on Psychosocial Aspects of Genetics (EMPAG) 2019

    • Year: 2019 -  Nsun5 in ribosome function and mammalian healthy lifespan

      Autoren: Liendl, L; Heissenberger, C; Nagelreiter, F; Plasenzotti, R; Grillari, J; Schosserer, M

      Event: BASEL LIFE

    • Year: 2019 -  CIRCULATING MIRNAS MIR-31-5P AND MIR-203A PREDICT INCIDENT FRAGILITY FRACTURES INDEPENDENTLY OF FRAX IN TYPE 2 DIABETIC POSTMENOPAUSAL WOMEN AND SIGNIFICANTLY IMPROVE FRAX'S ACCURACY FOR FRACTURE RISK PREDICTION IN DIABETIC BONE DISEASE

      Autoren: Heilmeier, U; Hackl, M; Schroeder, F; Torabi, S; Skalicky, S; Geiger, E; Vierlinger, K; Eiriksdottir, G; Gudmundsson, EF; Aspelund, TH; Harris, TB; Gudnason, V; Link, TM; Grillari, J; Schwartz, AV

      Event: World Congress on Osteoporosis, Osteoarthritis and Musculoskeletal Diseases (WCO-IOF-ESCEO)

    • Year: 2019 -  Two specific m5C-modifications of ribosomal RNA distinctly modulate healthy lifespan and development

      Autoren: Heissenberger, C; Krammer, TL; Stocker, I; Rollins, JA; Nagelreiter, F; Grillari, J; Lafontaine, DLJ; Rogers, A; Schosserer, M

      Event: Gordon Conference "Biology of Aging"

    • Year: 2019 -  A snorkel-tag based method for in vivo isolation of recombinant extracellular vesicles

      Autoren: Madhusudhan Reddy Bobbili, Stefan Vogt, Severin Muehleder, Carolina Patrioli, Samir Barbaria, Markus Schosserer, Wolfgang Holnthoner, Heinz Redl, André Görgens, Samir El Andaloussi and Johannes Grillari

      Event: International Society of Extracellular Vesicles - Annual Meeting 2019

    • Year: 2019 -  Laminin-targeted extracellular vesicles reveal enhanced specific uptake in vitro

      Autoren: Stefan Vogt, Madhusudhan Reddy Bobbili, Florian Rüker, Johannes Grillari, Gordana Wozniak-Knopp

      Event: 1st Annual Symposium of the Danish Society for Extracellular Vesicles (DSEV)

    • Year: 2019 -  Lyso-Pospholipids Contribute to the Inflammatory Nature of Senescent Dermal Fibroblasts

      Autoren: Pils, V; Sophie, M; Mildner, M; Nanic, L; Kremslehner, C; Waidhofer-Sollner, P; Rubelj, I; Jansen-Durr, P; Grillari, J; Gruber, F; Lammermann, I

      Event: 49th Annual Meeting of the European-Society-for-Dermatological-Research ESDR 2019

    • Year: 2019 -  Neuartige senolytische Substanzen basierend auf dem Arachidonsäure Metabolismus

      Autoren: Lämmermann, I; Pils, V; Narzt, MS; Nanic, L; Rubelj, I; Wilmes, A; Jennings, P; Gruber, F; Grillari, J

      Event: 14. Gemeinsamer Österreichisch-Deutscher Geriatriekongress

    • Year: 2019 -  Two specific m5C-modifications of ribosomal RNA distinctly modulate healthy lifespan and development

      Autoren: Heissenberger, C; Krammer, TL; Stocker, I; Rollins, JA; Nagelreiter, F; Grillari, J; Lafontaine, DLJ; Rogers, A; Schosserer, M

      Event: 3rd Molecular Biology of Ageing Meeting (ERIBA)

    • Year: 2019 -  Nsun5 in ribosome function and mammalian healthy lifespan

      Autoren: Liendl, L; Heissenberger, C; Nagelreiter, F; Plasenzotti, R; Grillari, J; Schosserer, M;

      Event: EMBO Workshop - Protein Synthesis and Translational Control

    • Year: 2019 -  Two specific m5C-modifications of ribosomal RNA distinctly modulate healthy lifespan and development

      Autoren: Heissenberger, C; Krammer, TL; Stocker, I; Rollins, JA; Nagelreiter, F; Grillari, J; Lafontaine, DLJ; Rogers, A; Schosserer, M

      Event: EMBO Workshop - Protein Synthesis and Translational Control

    • Year: 2019 -  The (Turm)Oil in Old Skin – Oxidized Phospholipids as Novel Contributors to the Pro-Inflammatory Nature of Senescent Dermal Fibroblasts

      Autoren: Pils, V; Narzt, M; Nagelreiter, I; Mildner, M; Nanic, L; Rubelj, I; Kremslehner, C; Branco, A; Wedel, S; Cavinato-Nascimento, M; Waidhofer-Söllner, P; Jansen-Dürr, P; Grillari, J; Gruber, F; Lämmermann, I

      Event: 4th ÖGDV Science Days

    • Year: 2018 -  Extracellular vesicle mediated cross talk of miRNAs in skin cell aging

      Autoren: Grillari, J

      Event: 9th International Conferenc on Skin Ageing and Challenges

    • Year: 2018 -  Specialized ribosomes in cellular senescence

      Autoren: Nagelreiter, F; Yang, G; Kos, M; Heissenberger, C; Gonskikh, Y; Polacek, N; Ratz, D; Grillari, J; Schosserer, M

      Event: Cold Spring Harbor Laboratory Meeting:Mechanism of Aging

    • Year: 2018 -  Utilizing in planta zein protein bodies for oral vaccine applications

      Autoren: Schwestka, J; Tschofen, M; Vogt, S; Grillari, J; Stöger, E

      Event: 10th ÖGMBT Annual Meeting & Biophysics Austria Annual Meeting 2018

    • Year: 2018 -  Skin cell senescence: a driver of skin aging and how to drive back

      Autoren: Grillari, J

      Event: Skin Physiology International Meeting

    • Year: 2018 -  Extracellular vesicles and their miRNA in aging and age-associated disease

      Autoren: Grillari J

      Event: 4th MSC Annual International Workshop 2018: SKIN AGEING

    • Year: 2018 -  Progerin expression in endothelial tissue leads to endothelial dysfunction and impaired diastolic cardiac function

      Autoren: Osmanagic-Myers, S; Kiss, A; Hamza, O; Sedlmayer, F; Fischer, I; Fichtinger, P; Grillari, J; Eriksson, M; Podesser, BK; Foisner, R

      Event: 5th Congress of the ESC-Council on Basic Cardiovascular Science 2018 - Frontiers in Cardio Vascular Biology

    • Year: 2018 -  NSUN5 methylates human and mouse 28S ribosomal RNA and modulates cell proliferation

      Autoren: Heissenberger, C; Nagelreiter, F; Stelzer, E; Krammer, T; Gonskikh, Y; Koš, M; Polacek, N; Grillari, J; Schosserer, M

      Event: EMBL Conference - The Epitranscriptome

    • Year: 2018 -  Base methylations of ribosomal RNA modulate healthy lifespan and development in C. elegans

      Autoren: Heissenberger, C; Rollins, JA; Krammer, T; Nagelreiter, F; Stelzer, E; Snow, S; Rogers, A; Grillari, J; Schosserer, M

      Event: EMBO Workshop: C. elegans development, cell biology and gene expression

    • Year: 2018 -  UNRAVELING THE DISTRIBUTION OF EXTRACELLULAR VESICLES IN VIVO USING RECOMBINANT TETRASPANINS

      Autoren: Madhusudhan Reddy Bobbili, Stefan Vogt, Severin Muehleder, Elsa Arcalis, Dietmar Pum, Carolina Patrioli, Samir Barbaria, Markus Schosserer, Wolfgang Holnthoner, Lucia Terlecki-Zaniewicz and Johannes Grillari

      Event: International Society for Extracellular Vesicles - Annual Meeting 2018

    • Year: 2018 -  Extracellular vesicles and miRNAs as members of the senescence associated secretory phenotype inhibit osteogenic differentiation and are biomarkers of osteoporosis

      Autoren: Grillari, J

      Event: TERMIS World Congress 2018

    • Year: 2018 -  Oxidized Phospholipid Species Contribute to the Pro-Inflammatory Activity of Senescent Fibroblasts

      Autoren: Pils, V; Narzt, M; Nagelreiter, I; Mildner, M; Nanic, L; Rubelj, I; Terlecki-Zaniewicz, L; Kremslehner, C; Branco, A; Grillari, J; Gruber, F; Lämmermann, I

      Event: Cold Spring Harbor Laboratory Meeting:Mechanism of Aging

    • Year: 2018 -  Circulating miRNAs are associated with higher tibial cortical porosity in postmenopausal women with history of osteoporotic fractures

      Autoren: Heilmeier, U; Hackl, M; Skalicky, S; Patsch, J; Baum, T; Schroder, F; Vierlinger, K; Burghardt, A; Schwartz, A; Grillari, J; Link, T

      Event: Annual Meeting of the American-Society-for-Bone-and-Mineral-Research

    • Year: 2018 -  Ribosomal RNA methylation by rram-1 modulates healthy lifespan

      Autoren: Heissenberger, C; Rollins, JA; Krammer, T; Nagelreiter, F; Stelzer, E; Snow, S; Rogers, A; Grillari, J; Schosserer, M

      Event: 10th ÖGMBT Annual Meeting & Biophysics Austria Annual Meeting 2018

    • Year: 2018 -  Extracellular vesicles and their miRNA in aging and age-associated disease

      Autoren: Grillari, J

      Event: EADV 2018

    • Year: 2018 -  Extracellular Vesicles Mediate SASP Functions in the Dermal-Epidermal Crosstalk During Senescence

      Autoren: Pils, V; Grillenberger, T; Schwestka, J; Lämmermann, I; Weinmüllner, R; Perrotta, I; Mildner, M; Morizot, F; Gruber, F; Grillari, J; Terlecki-Zaniewicz, L

      Event: 3rd ÖGDV Science Days

    • Year: 2018 -  Specific and label-free detection of cellular senescence by Raman microspectroscopy

      Autoren: Schosserer, M; Lang, M; Liendl, L; Nagelreiter, F; Weinmüllner, R; Grillari, J

      Event: 14th International Symposium on Neurobiology and Neuroendocrinology of Aging 2018

    • Year: 2018 -  A novel role for NUPR1 in the keratinocyte stress response to UV oxidized phospholipids

      Autoren: Narzt, M; Nagelreiter, I; Oskolkova, O; Bochkov, V; Latreille, J; Fedorova, M; Ni, Z; Sialana, F; Lubec, G; Filzwieser, M; Laggner, M; Bilban, M; Mildner, M; Tschachler, E; Grillari, J; Gruber, F

      Event: International Investigative Dermatology (IID) Meeting

    • Year: 2018 -  A novel role for NUPR1 in the keratinocyte stress response to UV oxidized phospholipids

      Autoren: Narzt, MS; Nagelreiter, IM; Oskolkova, O; Bochkov, V; Latreille, J; Fedorova, M; Ni, ZX; Sialana, FJ; Lubec, G; Filzwieser, M; Laggner, M; Bilban, M; Mildner, M; Tschachler, E; Grillari, J; Gruber, F

      Event: 19th Biennial Meeting of the Society-for-Free-Radical-Research-International (SFRRI)

    • Year: 2018 -  Extracellular vesicles and their cargo in aging and age-associated diseases

      Autoren: Grillari, J

      Event: ISEV 2018

    • Year: 2018 -  Base methylations of ribosomal RNA modulate healthy lifespan and development in C. elegans

      Autoren: Heissenberger, C; Rollins, JA; Krammer, T; Nagelreiter, F; Stelzer, E; Snow, S; Rogers, A; Grillari, J; Schosserer, M

      Event: Cold Spring Harbor Laboratory Meeting: Translational Control

    • Year: 2018 -  Nsun5 methylates 28S ribosomal RNA and modulates cell proliferation and aging

      Autoren: Liendl, L; Heissenberger, C; Krammer, T; Plasenzotti, R; Grillari, J; Schosserer, M

      Event: mouseAGE

    • Year: 2018 -  miRNAs as markers of bone health

      Autoren: Grillari, J

      Event: Workshop on metabolic bone diseases, Karolinska Institutet

    • Year: 2018 -  Oxidized Phospholipid Species Contribute to a Pro-Inflammatory Activity of Senescent Skin Fibroblasts

      Autoren: Narzt, M; Pils, V; Terlecki-Zaniewicz, L; Nagelreiter, I; Branco, A; Autheried, D; Tschachler, E; Gruber, F; Grillari, J; Lämmermann, I

      Event: 3rd ÖGDV Science Days

    • Year: 2018 -  iPSC and organoid technology

      Autoren: Grillari J; Grillari, R

      Event: ECTS 2018

    • Year: 2018 -  Ribosomal RNA methylation by rram-1 modulates healthy lifespan

      Autoren: Schosserer, M; Heissenberger, C; Krammer, T; Nagelreiter, F; Grillari, J

      Event: 14th International Symposium on Neurobiology and Neuroendocrinology of Aging 2018

    • Year: 2018 -  NSUN5 methylates 28S rRNA and modulates cell proliferation in humans and mice

      Autoren: Heissenberger, C; Nagelreiter, F; Grillari, J; Gonskikh, Y; Polacek, N; Kos, M; Stelzer, E; Krammer, T; Liendl, L; Schosserer, M

      Event: 10th ÖGMBT Annual Meeting & Biophysics Austria Annual Meeting 2018

    • Year: 2018 -  Oxidized Phospholipid Species Contribute to the Pro-Inflammatory Activity of Senescent Fibroblasts

      Autoren: Pils, V; Narzt, M; Nagelreiter, I; Mildner, M; Nanic, L; Rubelj, I; Terlecki-Zaniewicz, L; Kremslehner, C; Branco, A; Autheried, D; Grillari, J; Gruber, F; Lämmermann, I

      Event: 10th ÖGMBT Annual Meeting & Biophysics Austria Annual Meeting 2018

    • Year: 2018 -  Cellular senescence: a key event within AOPs?

      Autoren: Grillari, J

      Event: EUSAAT 2018

    • Year: 2018 -  Extracellular vesicles and their miRNA in aging and age-associated disease

      Autoren: Grillari, J

      Event: Keystone meeting on Pushing the Limits of Longevity and Health Span

    • Year: 2018 -  MiRNAs in extracellular vesicles: cross-talkings in aging and age-associated diseases

      Autoren: Grillari, J

      Event: 9TH ANNUAL ALLIANCE FOR HEALTHY AGING CONFERENCE 2018

    • Year: 2018 -  Senescent Human Fibroblasts Selectively Secrete miRNAs in Extracellular Vesicles and Modulate Keratinocyte Functionality During Skin Aging

      Autoren: Terlecki-Zaniewicz, L; Pils, V; Schwestka, J; Grillenberger, T; Lämmermann, I; Latreille, J; Reddy Bobbili, M; Weinmüllner, R; Higareda Almaraz, J; Scheideler, M; Pum, D; Perrotta, I; Morizot, F; Mildner, M; Gruber, F; Grillari, J

      Event: 3rd ÖGDV Science Days

    • Year: 2018 -  Specialized ribosomes in cellular senescence

      Autoren: Nagelreiter, F; Yang, G; Kos, M; Heissenberger, C; Gonskikh, Y; Polacek, N; Ratz, D; Grillari, J; Schosserer, M

      Event: 10th ÖGMBT Annual Meeting & Biophysics Austria Annual Meeting 2018

    • Year: 2018 -  Base methylations of ribosomal RNA modulate healthy lifespan and development in C. elegans

      Autoren: Heissenberger, C; Rollins, JA; Krammer, T; Nagelreiter, F; Stelzer, E; Snow, S; Rogers, A; Grillari, J; Schosserer, M

      Event: Cell Symposia: Aging and Metabolism

    • Year: 2017 -  Impact of resveratrol analogues on a 3D in vitro model of human skin

      Autoren: Nagelreiter, F; Weinmullner, R; Erker, T; Grillari, J; Schosserer, M

      Event: 13th International Symposium on the Neurobiology and Neuroendocrinology of Aging 2016

    • Year: 2017 -  Characterization of two ribosomal RNA base methylations modulating life- and healthspan

      Autoren: Schosserer, M; Minois, N; Rollins, JA; Heissenberger, C; Nagelreiter, F; Snow, S; Pfeifenberger, S; Breitenbach-Koller, L; Rogers, A; Grillari, J

      Event: Gordon Research Conference 2017 - Translation Machinery in Health & Disease

    • Year: 2017 -  Senescent human fibroblasts selectively secrete miRNAs in extracellular vesicles and modulate keratinocyte functionality during skin aging

      Autoren: Terlecki-Zaniewicz, L; Pils, V; Lammermann, I; Latreille, J; Pum, D; Scheideler, M; Almaraz, JCH; Morizot, F; Gruber, F; Grillari, J

      Event: 47th Annual Meeting of the European-Society-for-Dermatological-Research ESDR 2017

    • Year: 2017 -  Detection of cellular senescence by Raman microspectroscopy

      Autoren: Weinmüllner, R; Nagelreiter, F; Grillari, J; Schosserer, M

      Event: COST Action "Raman4Clinics" Annual Meeting

    • Year: 2017 -  Senescence-associated secretion of vesicular miR-23a-3p and its impact during the paracrine crosstalk of dermal and epidermal cells

      Autoren: Pils, V; Grillenberger, T; Schwestka, J; Lammermann, I; Weinmullner, R; Perrotta, I; Mildner, M; Morizot, F; Gruber, F; Grillari, J; Terlecki-Zaniewicz, L

      Event: 47th Annual Meeting of the European-Society-for-Dermatological-Research ESDR 2017

    • Year: 2017 -  Characterization of ribosomal RNA methylations modulating life- and healthspan of Caenorhabditis elegans

      Autoren: Schosserer, M; Rollins, JA; Heissenberger, C; Nagelreiter, F; Snow, S; Rogers, A; Grillari, J

      Event: 13th International Symposium on the Neurobiology and Neuroendocrinology of Aging 2016

    • Year: 2017 -  Two specific rRNA base methylations modulate healthy lifespan

      Autoren: Schosserer, M; Heissenberger, C; Nagelreiter, F; Grillari, J

      Event: 2nd Molecular Meeting on the Biology of Ageing

    • Year: 2017 -  Cost-Utility Analysis of Fracture-Risk Assessment Using MicroRNAs Compared to Standard Tools and No-Monitoring in the Austrian Female Population.

      Autoren: Walter, E; Dellago, H; Grillari, J; Dimai, HP; Hackl, M

      Event: Annual Meeting of the American-Society-for-Bone-and-Mineral-Research (ASBMR)

    • Year: 2017 -  Long-term exposure of immortalized keratinocytes to arsenic induces EMT, impairs differentiation in organotypic skin models and mimics aspects of human skin derangements

      Autoren: Grillari, J; Weinmullner, R; Kryeziu, K; Zbiral, B; Tav, K; Schoenhacker-Alte, B; Groza, D; Schosserer, M; Nagelreiter, F; Rosinger, S; Mildner, M; Tschachler, E; Grusch, M; Heffeter, P

      Event: 53rd Congress of the European-Societies-of-Toxicology (EUROTOX)

    • Year: 2017 -  From Cellular Senescence to Age-associated diseases: miRNAs as tools and targets for Healthy Ageing

      Autoren: Grillari, J

      Event: 3R Workshop Palermo, Università di Palermo, Italy

    • Year: 2017 -  miRNAs Enclosed in Small Extracellular Vesicles are Selectively Secreted and Retained in Cellular Senescence and Modulate Keratinocyte Functionality

      Autoren: Terlecki-Zaniewicz, L; Pils, V; Schwestka, J; Latreille, J; Lämmermann, I; Reddy Bobbili, M; Weinmüllner, R; Pum, D; Morizot, F; Hackl, M; Mildner, M; Gruber, F; Grillari, J

      Event: ISEV 2017

    • Year: 2017 -  From Senescence to Biomarkers via cell models: a journey with different hats

      Autoren: Grillari, J

      Event: First Austrian Science Coordination Workshop for in Vitro & in Silico Approaches

    • Year: 2017 -  OLR1 scavenger receptor knockdown affects mitotic gene expression but is dispensable for oxidized phospholipid- mediated stress signaling in SZ 95 sebocytes

      Autoren: Nagelreiter, IM; Parvardeh, M; Narzt, M; Beer, L; Kremslehner, C; Muresan, XM; Grillari, J; Zouboulis, CC; Tschachler, E; Gruber, F

      Event: 47th Annual Meeting of the European-Society-for-Dermatological-Research ESDR 2017

    • Year: 2017 -  Extracellular Vesicles and Their microRNA Cargo in Aging

      Autoren: Grillari, J

      Event: Symposium on extracellular Vesicles, Austrian Society for Extracellular Vesicles

    • Year: 2017 -  Long-term exposure of immortalized keratinocytes to arsenic induces EMT, impairs differentiation in organotypic skin models and mimics aspects of human skin derangements

      Autoren: Weinmüllner, R; Mildner, M; Grillari, J; Heffeter, P

      Event: Eurotox 2017

    • Year: 2017 -  NSUN5 methylates ribosomal RNA and modulates ribosome function in human cells

      Autoren: Heissenberger, C; Dimitrijevic, N; Gonskikh, Y; Linder, A; Grillari-Voglauer, R; Kos, M; Polacek, N; Grillari, J; Schosserer, M

      Event: 13th International Symposium on the Neurobiology and Neuroendocrinology of Aging 2016

    • Year: 2017 -  MicroRNAs as members of the senescence associated secretory phenotype influence cell fate decision

      Autoren: Grillari, J

      Event: Computational Approaches in Precision Medicine 2017

    • Year: 2017 -  miRNAs as members of the senescence associated secretory phenotype influence cell fate decision

      Autoren: Grillari, J

      Event: IUBMB 2017 Focused meeting molecular aspects of aging and longevity

    • Year: 2017 -  Biologische-Grundlagen-und-Grenzen-des-Alterns

      Autoren: Grillari, J

      Event: ÖPIA Ringvorlesung 2017

    • Year: 2017 -  miRNAs as members of the senescence associated secretory phenotype influence cell fate decision

      Autoren: Grillari, J

      Event: educational seminar series on aging at Mayo Clinic

    • Year: 2017 -  Circulating microRNA-203a is a novel biomarker for bone loss and response to anabolic therapy with PTH.

      Autoren: Kocijan, R; Geiger, E; Skalicky, S; Weigl, M; Leinfellner, G; Ferguson, J; Heimel, P; Redl, H; Grillari, J; Hackl, M

      Event: Annual Meeting of the American-Society-for-Bone-and-Mineral-Research (ASBMR)

    • Year: 2017 -  Two distinct ribosomal RNA base methylations modulate healthy lifespan

      Autoren: Schosserer, M; Rollins, JA; Heissenberger, C; Nagelreiter, F; Snow, S; Rogers, A; Grillari, J

      Event: Gordon Research Conference 2017 - Biology of Aging

    • Year: 2017 -  Blocking negative effects of senescence in human skin fibroblasts with a plant extract

      Autoren: Lammermann, I; Terlecki-Zaniewicz, L; Weinmullner, R; Schosserer, M; Berlin, I; Morizot, F; Lejeune, F; Fuzzati, N; Almaraz, JCH; Scheideler, M; Rietveld, M; El Ghalbzouri, A; Tschachler, E; Gruber, F; Grillari, J

      Event: 47th Annual Meeting of the European-Society-for-Dermatological-Research ESDR 2017

    • Year: 2017 -  Global Protein Synthesis in Mammalian Cellular Senescence

      Autoren: Nagelreiter, F; Heissenberger, C; Lämmermann, I; Terlecki-Zaniewicz, L; Grillari, J; Schosserer, M

      Event: Gordon Research Conference 2017 - Translation Machinery in Health & Disease

    • Year: 2017 -  miR-550a-5p inhibits osteogenic differentiation of immortalized human mesenchymal stem cells.

      Autoren: Hackl, M; Wiedemann, V; Skalicky, S; Geiger, E; Kassem, M; Soul, J; Schwartz, JM; Schleicher, T; Kumar, Y; Grillari, J

      Event: Annual Meeting of the American-Society-for-Bone-and-Mineral-Research (ASBMR)

    • Year: 2017 -  Characterization of two ribosomal RNA base methylations modulating life- and healthspan

      Autoren: Schosserer, M; Minois, N; Rollins, JA; Heissenberger, C; Nagelreiter, F; Snow, S; Pfeifenberger, S; Breitenbach-Koller, L; Rogers, A; Grillari, J

      Event: Gordon Research Conference 2017 - Translation Machinery in Health & Disease

    • Year: 2017 -  A "multi-omic" investigation of the effects of long wavelength ultraviolet light on primary human keratinocytes identifies NUPR1 as central stress response mediator

      Autoren: Narzt, MS; Nagelreiter, IM; Bochkov, VN; Latreille, J; Sialana, F; Lubec, G; Fedorova, M; Ni, ZX; Filzwieser, M; Grillari, J; Beer, L; Tschachler, E; Gruber, F

      Event: OCC World Congress / Annual SFRR-E Conference

    • Year: 2017 -  Two specific rRNA base methylations modulate healthy lifespan

      Autoren: Schosserer, M; Heissenberger, C; Nagelreiter, F; Grillari, J

      Event: Gordon Research Conference 2017 - Biology of Aging

    • Year: 2017 -  The Extravesicular miRNome of Senescent Human Fibroblasts and its Impact on Keratinocyte Functionality

      Autoren: Terlecki-Zaniewicz, L; Pils, V; Schwestka, J; Latreille, J; Lämmermann, I; Reddy Bobbili, M; Weinmüllner, R; Berlin, I; Pum, D; Morizot, F; Hackl, M; Mildner, M; Gruber, F; Grillari, J

      Event: 2nd ÖGDV Science Days

    • Year: 2017 -  Secreted mirnas from senescent cells modulate differentiation of target cells

      Autoren: Grillari, J

      Event: Departmental seminar, University of Duesseldorf and IUF - Leibniz Research Institute for Environmental Medicine, Working Group IRTG1902

    • Year: 2017 -  Tauchen im Jungbrunnen - Chancen und Grenzen der Alternsforschung

      Autoren: Schosserer, M; Grillari, J

      Event: Die Wiener Volkshochschulen - Science (Planetarium Wien)

    • Year: 2017 -  Multi-omics identify nuclear protein 1 (Nupr1/p8) as central regulator of redox stress mediated by ultraviolet A light

      Autoren: Narzt, M; Nagelreiter, IM; Bochkov, V; Latreille, J; Fedorova, M; Ni, Z; Sialana, F; Lubec, G; Bilban, M; Tschachler, E; Grillari, J; Gruber, F

      Event: 47th Annual Meeting of the European-Society-for-Dermatological-Research ESDR 2017

    • Year: 2016 -  Impact of resveratrol analogues on a 3D in vitro model of human skin

      Autoren: Nagelreiter, F; Weinmüllner, R; Erker, T; Grillari, J; Schosserer, M

      Event: The Thirteenth International Symposium on Neurobiology and Neuroendocrinology of Aging

    • Year: 2016 -  Characterization of ribosomal RNA methylations modulating life- and healthspan

      Autoren: Schosserer, M; Minois, N; Rollins, JA; Heissenberger, C; Nagelreiter, F; Snow, S; Pfeifenberger, S; Breitenbach-Koller, L; Rogers, A; Grillari, J

      Event: 8th ÖGMBT Annual Meeting 2016

    • Year: 2016 -  Secretory activity of senescent human fibroblasts is alleviated by plant extracts – Christian Doppler Laboratory for Biotechnology of skin aging

      Autoren: Johannes Grillari

      Event: ESDR 2016

    • Year: 2016 -  Zirkulierende miRNAs als biomarker in der Osteoporose

      Autoren: Johannes Grillari

      Event: Menopause Antiaging Kongress 2016

    • Year: 2016 -  Characterization of ribosomal RNA methylations modulating life- and healthspan

      Autoren: Schosserer, M; Minois, N; Rollins, JA; Heissenberger, C; Nagelreiter, F; Snow, S; Pfeifenberger, S; Breitenbach-Koller, L; Rogers, A; Grillari, J

      Event: 13th International Symposium on Neurobiology and Neuroendocrinology of Aging 2016

    • Year: 2016 -  miRNAs as Members of the Senescence Associated Secretory Phenotype Influence Cell Fate decision

      Autoren: Johannes Grillari

      Event: Cell fate and diversity in aging conference

    • Year: 2016 -  Studying the effects of senescent cells on skin formation in a newly developed three-dimensional tissue model for skin aging

      Autoren: Weinmullner, R; Mildner, M; Terlecki-Zaniewicz, L; Schosserer, M; Lammermann, I; Tschachler, E; Gruber, F; Grillari, J

      Event: Annual Meeting of the European-Society-for-Dermatological-Research ESDR 2016

    • Year: 2016 -  NSUN5 methylates ribosomal RNA and modulates ribosome function in human cells

      Autoren: Heissenberger, C; Dimitrijevic, N; Linder, A; Grillari-Voglauer, R; Grillari J; Schosserer, M

      Event: 13th International Symposium on Neurobiology and Neuroendocrinology of Aging 2016

    • Year: 2016 -  A "multi-omic" investigation of the effects of long wavelength ultraviolet light on primary human keratinocytes

      Autoren: Narzt, MS; Nagelreiter, IM; Bochkov, VN; Latreille, J; Fedorova, M; Ni, ZX; Filzwieser, M; Qin, HH; Terlecki, L; Hackl, M; Grillari, J; Beer, L; Bilban, M; Tschachler, E; Gruber, F

      Event: Conference of the Society-for-Free-Radical-Research-Europe (SFRR-E)

    • Year: 2016 -  Ageing and treatment options

      Autoren: Grillari, J

      Event: 25th EADV Congress 2016

    • Year: 2016 -  A "multi-omic" investigation of the effects of long wavelength ultraviolet light on primary human keratinocytes

      Autoren: Narzt, M; Nagelreiter, IM; Bochkov, V; Latreille, J; Fedorova, M; Ni, Z; Grillari, J; Tschachler, E; Gruber, F

      Event: Annual Meeting of the European-Society-for-Dermatological-Research ESDR 2016

    • Year: 2016 -  Autophagy deficient keratinocytes display increased DNA damage and senescence markers after oxidative stress in vitro and in vivo

      Autoren: Song, X; Narzt, M; Nagelreiter, IM; Hohensinner, P; Tschachler, E; Grillari, J; Gruber, F

      Event: Annual Meeting of the European-Society-for-Dermatological-Research ESDR 2016

    • Year: 2016 -  NSUN5 methylates ribosomal RNA and modulates ribosome function in human cells

      Autoren: Heissenberger, C; Dimitrijevic, N; Nagelreiter, F; Gonskikh, Y; Linder, A; Grillari-Voglauer, R; Grillari J; Schosserer, M

      Event: 8th ÖGMBT Annual Meeting, Life Sciences for the next generation 2016

    • Year: 2016 -  Immortal human primary like cells: relevant and standardizable model systems

      Autoren: Johannes Grillari

      Event: 3rd Austrian Biomarker Symposium

    • Year: 2016 -  Characterization of ribosomal RNA methylations modulating life- and healthspan

      Autoren: Schosserer, M; Minois, N; Rollins, JA; Heissenberger, C; Nagelreiter, F; Snow, S; Pfeifenberger, S; Breitenbach-Koller, L; Rogers, A; Grillari, J

      Event: Cell Symposia: Aging and Metabolism

    • Year: 2016 -  MiRNAs, senescence and the bone: from molecular function to bloodbased biomarkers and back

      Autoren: Johannes Grillari

      Event: New Advances in Bone Diseases

    • Year: 2016 -  Characterization of ribosomal RNA methylations modulating life- and healthspan of Caenorhabditis elegans

      Autoren: Schosserer, M; Rollins, JA; Heissenberger, C; Nagelreiter, F; Snow, S; Rogers, A; Grillari, J

      Event: European Worm Meeting (EWM) 2016

    • Year: 2016 -  The Extravesicular miRNome of Senescent Human Fibroblasts and its Impact on Keratinocyte Functionality

      Autoren: Terlecki-Zaniewicz, L; Pils, V; Schwestka, J; Latreille, J; Lämmermann, I; Weinmüllner, R; Berlin, I; Hackl, M; Morizot, F; Grillari, J

      Event: ISEV 2016

    • Year: 2016 -  Impact of resveratrol analogues on a 3D in vitro model of human skin

      Autoren: Nagelreiter, F; Weinmüllner, R; Erker, T; Grillari, J; Schosserer, M.

      Event: 8th ÖGMBT Annual Meeting, Life Sciences for the next generation 2016

    • Year: 2016 -  The extravesicular miRNome of senescent human fibroblasts and its impact on keratinocyte functionality

      Autoren: Terlecki-Zaniewicz, L; Pils, V; Schwestka, J; Latreille, J; Lammermann, I; Weinmullner, R; Berlin, I; Hackl, M; Morizot, F; Grillari, J

      Event: Annual Meeting of the European-Society-for-Dermatological-Research ESDR 2016

    • Year: 2015 -  Characterization of NSUN5 in human cell lines - a novel lifespan-modulating rRNA methyltransferase

      Autoren: Schosserer, M; Minois, N; Angerer, TB; Amring, M; Dellago, H; Harreither, E; Böck,T; Siena, E; Gerstl, MP; Pfeifenberger, S; Pircher, A; Brandl, C; Weinhäusel, A; Breitenbach, M; Wilson, IBH; Grillari-Voglauer, R; Polacek, N; Breitenbach-Koller, L; Grillari, J

      Event: 7th ÖGMBT Annual Meeting 2015

    • Year: 2015 -  Development of a three-dimensional tissue model for skin aging

      Autoren: Weinmullner, R; Mildner, M; Terlecki-Zaniewicz, L; Schosserer, M; Lammermann, I; Gruber, F; Tschachler, E; Grillari, J

      Event: 45th Annual Meeting of the European-Society-for-Dermatological-Research

    • Year: 2015 -  High levels of onco-miR-21 contribute to the senescence-induced growth arrest in normal human cells and its knock-down increases the replicative lifespan

      Autoren: Dellago, H; Preschitz-Kammerhofer, B; Terlecki-Zaniewicz, L; Schreiner, C; Fortschegger, K; Chang, MWF; Hackl, M; Monteforte, R; Kuhnel, H; Schosserer, M; Gruber, F; Tschachler, E; Scheideler, M; Grillari-Voglauer, R; Grillari, J; Wieser, M

      Event: 12th International Symposium on the Neurobiology and Neuroendocrinology of Aging 2015

    • Year: 2015 -  Biologie des Alterns

      Autoren: J. Grillari

      Event: ÖAK Diplomlehrgang für Geriatrie 2015

    • Year: 2015 -  From replicative senescence to diagnostics of age-associated diseases: a story of translation

      Autoren: Matthias Hackl, Otto Kanzler, Regina Grillari-Voglauer, and Johannes Grillari

      Event: Gordon Biology of Aging Conference 2015

    • Year: 2015 -  Methylation of ribosomal RNA by NSUN5 is a conserved mechanism modulating organismal life span and oxidative stress resistance

      Autoren: Schosserer, M; Minois, N; Angerer, TB; Amring, M; Dellago, H; Harreither, E; Gerstl, MP; Pfeifenberger, S; Pircher, A; Brandl, C; Weinhäusel, A; Breitenbach, M; Wilson, IBH; Grillari-Voglauer, R; Polacek, N; Breitenbach-Koller, L; Grillari, J

      Event: Oxygen Club of California World Congress

    • Year: 2015 -  Overexpression of the DNA repair factor SNEV/hPrp19/hPso4 extends cellular and organismal life span and increases resistance to genotoxic stress

      Autoren: Dellago, Khan A, Schosserer M, Flatt T, Ammerer G, Jansen-Dürr P, Rudolph KL, Grillari-Voglauer R, Grillari J

      Event: Wiener Kongress für Geriatrie und Gerontologie - 10. gemeinsamer österreichisch-deutscher Geriatriekongress

    • Year: 2015 -  The DNA repair factor SNEV/hPrp19/hPso4 regulates cellular and organismal life span and promotes adipogenic differentiation.

      Autoren: Dellago H, Khan H, Monteforte R, Schosserer M, Flatt T, Grillari-Voglauer R, Grillari J

      Event: Tomas Lindahl conference on DNA repair

    • Year: 2015 -  Methylation of ribosomal RNA by NSUN5 is a conserved mechanism modulating organismal life span

      Autoren: Schosserer, M; Minois, N; Angerer, TB; Amring, M; Dellago, H; Harreither, E; Gerstl, MP; Pfeifenberger, S; Pircher, A; Brandl, C; Weinhäusel, A; Breitenbach, M; Wilson, IBH; Grillari-Voglauer, R; Polacek, N; Breitenbach-Koller, L; Grillari, J

      Event: Gordon Research Seminar and Conference

    • Year: 2015 -  Lipid oxidation patterns and -kinetics under senescence-promoting stress in keratinocytes

      Autoren: Narzt, M; Nagelreiter, IM; Karner, S; Grillari, J; Figlak, K; Filzwieser, M; Bochkov, VN; Tschachler, E; Gruber, F

      Event: 42nd Annual Meeting of the Arbeitsgemeinschaft-Dermatologische-Forschung (ADF)

    • Year: 2015 -  SNEVhPrp19/hPSO4 haploinsufficiency accelerates premature skin aging in response to 8-methoxypsoralen/UVA treatment in mice

      Autoren: Monteforte, R; Beilhack, GF; Grillari-Voglauer, R; Grausenburger, R; Sibilia, M; Tschachler, E; Gruber, F; Grillari, J

      Event: 12th International Symposium on the Neurobiology and Neuroendocrinology of Aging 2015

    • Year: 2015 -  Immortalized human cells: current approach in organ toxicity testing

      Autoren: Grillari, R; Grillari, J; Manhart, G; Lämmermann, I; Uhl, M; Paparella, M; Fürhacker, M;

      Event: 25th Annual Meeting SETAC Europe 2015

    • Year: 2015 -  Establishment of keratinocyte cell lines from human hair follicles

      Autoren: Berger, T; Gschwandtner, M; Strajeriu, A; Elbe-Burger, A; Grillari, J; Grillari-Voglauer, R; Tschachler, E; Mildner, M

      Event: 42nd Annual Meeting of the Arbeitsgemeinschaft-Dermatologische-Forschung (ADF)

    • Year: 2015 -  Therapeutic ribosomes: Ribosomal proteins as targets for systemic therapy

      Autoren: Friedrich, A; Brandl, C; Karl, T; Wimmer, B; Klausegger, A; Breitenbach, M; Hintner, H; Schosserer, M; Grillari, J; Bauer, JW; Breitenbach-Koller, H

      Event: Gordon Research Conference 2015 - Translation Machinery in Health & Disease

    • Year: 2015 -  Overexpression of the DNA repair factor SNEVhPrp19/hPso4 extends cellular and organismal life span and increases resistance to genotoxic stress

      Autoren: Dellago, H; Khan, A; Schosserer, M; Flatt, T; Ammerer, G; Jansen-Durr, P; Rudolph, KL; Grillari-Voglauer, R; Grillari, J

      Event: 12th International Symposium on the Neurobiology and Neuroendocrinology of Aging 2015

    • Year: 2015 -  Extrazelluläre Vesikel im Alterungsprozess und bei Erkrankungen

      Autoren: Grillar J

      Event: Hyperflow 2015

    • Year: 2015 -  miRNA and Ageing

      Autoren: Grillari, J

      Event: Healthy Ageing Research Center, Conference on Translational Research in Healthy Ageing

    • Year: 2015 -  Lipid oxidation patterns and kinetics in keratinocytes undergoing senescence-promoting stress or replicative senescence

      Autoren: Narzt, MS; Nagelreiter, IM; Karner, S; Grillari, J; Figlak, K; Filzwieser, M; Bochkov, V; Tschachler, E; Gruber, F

      Event: Annual Meeting of the Society-for-Investigative-Dermatology 2015

    • Year: 2015 -  Methylation of ribosomal RNA by NSUN5 is a conserved mechanism modulating organismal life span.

      Autoren: Schosserer, M; Minois, N; Angerer, TB; Amring, M; Dellago, H; Harreither, E; Gerstl, MP; Pfeifenberger, S; Pircher, A; Brandl, C; Weinhäusel, A; Breitenbach, M; Wilson, IBH; Grillari-Voglauer, R; Polacek, N; Breitenbach-Koller, L; Grillari, J

      Event: Aging: Cellular Mechanisms and Therapeutic Opportunities, a Herrenhausen Symposium

    • Year: 2014 -  miRNAs in cellular and organismal aging

      Autoren: Johannes Grillari

      Event: Departmental Seminar, UT Southwestern Medical Center, Dallas, USA

    • Year: 2014 -  Micro-RNAs als diagnostisches und therapeutisches Werkzeug bei Osteoporose

      Autoren: Johannes Grillari

      Event: Menopause, Andropause, Antiaging 2014

    • Year: 2014 -  High levels of oncomiR-21 contribute to the senescence-induced growth arrest in normal human cells and its knock-down increases the replicative lifespan

      Autoren: Dellago, H; Preschitz-Kammerhofer, B; Terlecki-Zaniewicz, L; Schreiner, C; Fortschegger, K; Chang, MWF; Hackl, M; Monteforte, R; Schosserer, M; Gruber, F; Tschachler, E; Scheideler, M; Grillari-Voglauer, R; Grillari, J; Wieser, M

      Event: Twelfth International Symposium on Neurobiology and Neuroendocrinology of Aging

    • Year: 2014 -  Overexpression of the DNA repair factor SNEVhPrp19/hPso4 extends cellular and organismal life span and increases resistance to genotoxic stress

      Autoren: Dellago, H; Khan, A; Schosserer, M; Flatt, T; Ammerer, G; Jansen-Dürr, P; Rudolph, KL; Grillari-Voglauer, R; Grillari, J

      Event: Twelfth International Symposium on Neurobiology and Neuroendocrinology of Aging

    • Year: 2014 -  SNEVhPrp19/hPSO4 haploinsufficiency accelerates premature skin aging in response to 8-methoxypsoralen/UVA treatment in mice

      Autoren: Rossella Monteforte1, Georg F. Beilhack2, Regina Grillari-Voglauer1, 3, Maria Sibilia4, Erwin Tschachler5, Florian Gruber5, 6* and Johannes Grillari1, 3, 6* 1 Department of Biotechnology, University of Natural Resources and Applied Life Sciences, Vienna, Austria 2 Division of Nephrology & Dialysis, Internal Medicine III, Medical University of Vienna, Vienna, Austria 3 Evercyte GmbH, 1190 Vienna, Austria 4 Istitute for Cancer Research, Medical University of Vienna, Vienna, Austria 5 Department of Dermatology, Medical University of Vienna, Vienna, Austria 6 Christian Doppler Laboratory on Biotechnology of Skin Aging, Vienna, Austria

      Event: Montagna Symposium on the Biology of Skin: Skin Aging Molecuar Mechanisms and Tissue Consequences

    • Year: 2014 -  Overexpression of dPrp19, the fly homolog of SNEVhPrp19/hPso4, extends Drosophila life span

      Autoren: Schosserer, M; Dellago, H; Flatt, T; Grillari, J

      Event: Keystone Symposium: Aging: Pushing the Limits of Cellular Quality Control

    • Year: 2014 -  SNEVhPrp19/hPSO4 haploinsufficiency accelerates premature skin aging in response to 8-methoxypsoralen/UVA treatment in mice

      Autoren: Monteforte, R; Beilhack, G; Grillari-Vogelauer, R; Sibilia, M; Tschachler, E; Gruber, F; Grillari, J

      Event: 44th Annual Meeting of the European-Society-for-Dermatological-Research ESDR 2014

    • Year: 2014 -  Age-dependent influence of plasma derived extracellular vesicles on osteogenic differentiation capacity of mesenchymal stem cells

      Autoren: S. Weilner, E. Schraml, V. Keider, K.H. Schneider, K. Wassermann, H. Redl, P. Pietschmann, J. Grillari.

      Event: Young scientist association

    • Year: 2014 -  Found in translation: Ribosome modification by Nsun5 is a conserved longevity factor

      Autoren: Schosserer, M; Minois, N; Angerer, TB; Amring, M; Dellago, H; Harreither, E; Gerstl, MP; Pfeifenberger, S; Brandl, C; Rinnerthaler, M; Sonntagbauer, M; Linder, A; Weinhäusel, A; Breitenbach, M; Wilson, IBH; Grillari-Voglauer, R; Breitenbach-Koller, L; Grillari, J

      Event: Keystone Symposium: Aging: Pushing the Limits of Cellular Quality Control

    • Year: 2014 -  miRNAs and matrix vesicles and bone

      Autoren: Johannes Grillari

      Event: CORS Symposium; Micro-RNAs in Bone Health and Disease

    • Year: 2014 -  Age-dependent loss of microvesicular Galectin-3 and its consequences on bone formation in vitro and in vivo

      Autoren: S. Weilner, E. Schraml, V. Keider, K.H. Schneider, K. Wassermann, H. Redl, P. Pietschmann, J. Grillari

      Event: World Congress on Osteoporosis, Osteoarthritis and Musculoskeletal Diseases

    • Year: 2014 -  Diving into the fountain of youth: novel factors modulating the cellular and organismal life span.

      Autoren: Johannes Grillari

      Event: Vortrag an der Universität Bern, Seminare in Biochemie

    • Year: 2014 -  LEVELS OF CIRCULATING VESICULAR MICRORNA-31 INCREASE WITH AGE AS WELL AS IN THE CASE OF OSTEOPOROSIS AND INHIBIT OSTEOGENIC DIFFERENTIATION CAPACITY OF MESENCHYMAL STEM CELLS

      Autoren: Weilner, S; Schraml, E; Wassermann, K; Wieser, M; Messner, P; Schneider, K; Micutkova, L; Fortschegger, K; Maier, AB; Westendorp, R; Resch, H; Wolbank, S; Redl, H; Jansen-Durr, P; Pietschmann, P; Grillari-Voglauer, R; Grillari, J

      Event: World Congress on Osteoporosis, Osteoarthritis and Musculoskeletal Diseases

    • Year: 2014 -  AGE-DEPENDENT LOSS OF MICROVESICULAR GALECTIN-3 AND ITS CONSEQUENCES ON BONE FORMATION IN VITRO AND IN VIVO

      Autoren: Weilner, S; Heimel, P; Keider, V; Schraml, E; Weiss, F; Grillari-Voglauer, R; Redl, H; Chen, HY; Grillari, J

      Event: World Congress on Osteoporosis, Osteoarthritis and Musculoskeletal Diseases

    • Year: 2014 -  High levels of oncomiR-21 contribute to the senescence-induced growth arrest in normal human cells and its knock-down increases the replicative lifespan

      Autoren: Dellago, H; Preschitz-Kammerhofer, B; Terlecki-Zaniewicz, L; Schreiner, C; Fortschegger, K; Chang, MWF; Hackl, M; Monteforte, R; Schosserer, M; Gruber, F; Tschachler, E; Scheideler, M; Grillari-Voglauer, R; Grillari, J; Wieser, M

      Event: The Twelfth International Symposium on Neurobiology and Neuroendocrinology of Aging

    • Year: 2014 -  New molecular biotechnology in toxicology

      Autoren: Johannes Grillari

      Event: 18th International Congress on In Vitro Toxicology, ESTIV 2014

    • Year: 2014 -  Donor age dependent influence of circulating extracellular vesicles on in vitro bone formation

      Autoren: Sylvia Weilner

      Event: Wissenschaftliche Herbsttagung der Österreichische Gesellschaft für Knochen und Mineralstoffwechsel 2014

    • Year: 2014 -  Methylation of ribosomal RNA by NSUN5 is a conserved mechanism modulating organismal life span

      Autoren: Schosserer, M; Minois, N; Angerer, TB; Amring, M; Dellago, H; Harreither, E; Gerstl, MP; Pfeifenberger, S; Brandl, C; Rinnerthaler, M; Sonntagbauer, M; Linder, A; Weinhäusel, A; Breitenbach, M; Wilson, IBH; Grillari-Voglauer, R; Breitenbach-Koller, L; Grillari, J

      Event: Zing Conference: "Biology of Human Aging"

    • Year: 2014 -  SNEV haploinsufficiency accelerates premature skin aging in response to 8-methoxypsoralen/UVA treatment in mice

      Autoren: Rossella Monteforte1, Reinhard Grausenburger1, Florian Gruber2, Erwin Tschachler2 and Johannes Grillari1 1 Dept. of Biotechnology, University of Natural Resources and Applied Life Sciences, Vienna, Austria 2 Dept. of Dermatology, Medical University of Vienna, Austria

      Event: ESDR 2014 Konferenz

    • Year: 2014 -  CIRCULATING MICRORNAS IN BONE DISEASE

      Autoren: Hackl, M; Weilner, S; Skalicky, S; Schraml, E; Heilmeier, U; Link, T; Redl, H; Dovjak, P; Pietschmann, P; Grillari-Voglauer, R; Grillari, J

      Event: World Congress on Osteoporosis, Osteoarthritis and Musculoskeletal Diseases

    • Year: 2014 -  Lipid oxidation patterns and -kinetics in keratinocytes under senescence-promoting stress

      Autoren: Narzt, M; Nagelreiter, I; Karner, S; Grillari, J; Figlak, K; Filzwieser, M; Bochkov, V; Tschachler, E; Gruber, F

      Event: 44th Annual Meeting of the European-Society-for-Dermatological-Research ESDR 2014

    • Year: 2014 -  Levels of circulating vesicular microRNA-31 increase with age as well as in the case of osteoporosis and inhibit osteogenic differentiation of mesenchymal stem cells

      Autoren: S. Weilner, E. Schraml, V. Keider, K.H. Schneider, K. Wassermann, H. Redl, P. Pietschmann, J. Grillari

      Event: European Calcified Tissue Society Congress

    • Year: 2014 -  Levels of circulating vesicular microRNA-31 increase with age as well as in the case of osteoporosis and inhibit osteogenic differentiation of mesenchymal stem cells

      Autoren: S. Weilner, E. Schraml, V. Keider, K.H. Schneider, K. Wassermann, H. Redl, P. Pietschmann, J. Grillari.

      Event: World Congress on Osteoporosis, Osteoarthritis and Musculoskeletal Diseases

    • Year: 2014 -  miRNAs in cellular and organismal aging: the stress connection, Geriatrics and Gerontology meeting

      Autoren: Johannes Grillari

      Event: Stress und Altern – Chancen und Risiken - Gerontologie-Geriatrie-Kongress 2014

    • Year: 2013 -  Overexpression of the conserved DNA repair factor SNEV/hPrp19/hPso4 extends cellular and organismal life span and increases resistance to genotoxic stress

      Autoren: Dellago, H; Khan, A; Schosserer, M; Flatt, T; Ammerer, G; Jansen-Dürr, P; Rudolph, KL; Grillari-Voglauer, R; Grillari, J

      Event: EMBO Conference 2013 - The DNA damage response in cell physiology and disease”

    • Year: 2013 -  Relevante, standardisierbare Zellmodelle

      Autoren: Grillari, J

      Event: Cell Culture Days 2013

    • Year: 2013 -  MiRNAs: novel factors modulating the aging process

      Autoren: Grillari, J

      Event: Departmental Seminar Host: Primar Gabriel

    • Year: 2013 -  Diving into the fountain of youth: novel factors modulating the cellular and organismal life span

      Autoren: Grillari, J

      Event: Departmental Seminar, Heidelberg University, host: Martin Kos

    • Year: 2013 -  Immortalized primary-like human cells as novel model systems in nephrotoxicity

      Autoren: Grillari, J

      Event: EUSAAT Conference 2013

    • Year: 2013 -  Small non-coding RNAs – pathway engineering of CHO cell factories that avoids translational burdening

      Autoren: Grillari, J

      Event: 11th PEACE (Protein Expression in Animal Cells) Conference

    • Year: 2013 -  Ribosome modification by Nsun5 is a conserved longevity factor

      Autoren: Schosserer, M; Minois, N; Amring, M; Angerer, TB; Harreither, E; Aichinger, C; Micutkova, L; Jansen-Dürr, P; Grillari-Voglauer, R; Breitenbach, M; Wilson, IB; Breitenbach-Koller, L; Grillari, J

      Event: 5th ÖGMBT Life Science Meeting

    • Year: 2013 -  Relevant cell model systems

      Autoren: Grillari, J

      Event: FP7 final symposium

    • Year: 2013 -  Urine derived renal proximal tubular epithelial cells: a non-invasive cell source

      Autoren: Grillari, J

      Event: Kidney: Development, Disease and Novel Therapies NephroTools 1st International Conference

    • Year: 2013 -  MiRNAs – pathway engineering of CHO cell factories that avoids translational burdening

      Autoren: Grillari, J

      Event: 7th Conference on Recombinant Protein Production RPP7 2013

    • Year: 2013 -  Identification and characterization of novel modulators of the cellular and organismal life span

      Autoren: Johannes Grillari

      Event: Zing Conference on Mitochondria, metabolic regulation and the biology of aging

    • Year: 2013 -  Overexpression of the conserved DNA repair factor SNEVhPrp19/hPso4 extends cellular and organismal life span and increases resistance to genotoxic stress

      Autoren: Dellago, H; Khan, A; Schosserer, M; Nussbacher, M; Gstraunthaler, A; Lämmermann, I; Mück, C; Anrather, D; Scheffold, D; Gáliková, M; Flatt, T; Ammerer, G; Jansen-Dürr, P; Rudolph, KL; Grillari-Voglauer, R; Grillari, J

      Event: V. Else Kröner-Fresenius Symposium on Adult Stem Cells in Aging, Diseases, and Cancer

    • Year: 2013 -  Novel factors modulating cellular and organismal longevity

      Autoren: Grillari, J

      Event: Kick – off Meeting on the CD Laboratory Biotechnology of Skin Aging 2013

    • Year: 2012 -  The role of Dicer and Drosha controlled microRNA biogenesis in CHO cells.

      Autoren: Hackl M., Jadhav V., Grillari J., Borth N.

      Event: 13th Cell Culture Engineering Conference 2012

    • Year: 2012 -  Nsun5, a novel conserved stress-responsive RNA- methyltransferase modulates translation and animal lifespan

      Autoren: Schosserer, M; Minois, N; Amring, M; Angerer, TB; Harreither, E; Aichinger, C; Micutkova, L; Jansen-Dürr, P; Grillari-Voglauer, R; Breitenbach, M; Wilson, IB; Breitenbach-Koller, L; Grillari, J

      Event: 4th ÖGMBT Annual Meeting 2012

    • Year: 2012 -  SNEV haploinsufficiency accelerates premature skin aging in response to 8-methoxypsoralen/UVA treatment in mice

      Autoren: Monteforte, R; Gruber, F; Tschachler, E; Grillari, J

      Event: 42nd Annual Meeting of the European Society for Dermatological Research ESDR 2012

    • Year: 2012 -  Using CHO genome sequence databases for miRNA engineering.

      Autoren: Borth N., Hackl M., Vaibhav J., Grillari J.

      Event: 13th Cell Culture Engineering Conference 2012

    • Year: 2012 -  WNT/CTNNB1 pathway inhibition guides the human thymic involution process

      Autoren: Ferrando-Martinez, S; de Pablo-Bernal, RS; Munoz-Fernandez, MA; van den Brink, MR; Grillari, J; Ruiz-Mateos, E; Leal, M

      Event: European Congress of Immunology 2012

    • Year: 2012 -  Computational identification of miRNA gene loci and precursor miRNA sequences in CHO cell lines.

      Autoren: Hackl M., Jadhav V., Jakobi T., Rupp O., Brinkrolf K., Goesmann A., Pühler A., Noll T., Borth N., Grillari J.

      Event: 13th Cell Culture Engineering Conference 2012

    • Year: 2012 -  ATM-dependent phosphorylation of SNEVhPrp19/hPso4 is involved in extending cellular life span and suppression of apoptosis

      Autoren: Dellago, H; Khan, A; Nussbacher, M; Gstraunthaler, A; Lämmermann, I; Schosserer, M; Mück, C; Anrather, D; Scheffold, A; Ammerer, G; Jansen-Dürr, P; Rudolph, KL; Voglauer-Grillari, R; Grillari, J

      Event: Meeting at the Cold Spring Harbor Laboratory Molecular Genetics of Aging 2012

    • Year: 2012 -  The molecular regulation of miR-17-92 cluster enhancing cellular growth in CHO cells.

      Autoren: Jadhav V., Hackl M., Hernandez-Bort J., Grillari J., Borth N.

      Event: 13th Cell Culture Engineering Conference 2012

    • Year: 2012 -  Engineering of CHO cellular phenotype.

      Autoren: Borth N. Hackl M., Klanert G., Jadhav V., Grillari J.

      Event: JAACT International Meeting 2012

    • Year: 2012 -  Nsun5, a novel conserved stress-responsive RNA- methyltransferase modulates translation and animal lifespan

      Autoren: Schosserer, M; Minois, N; Amring, M; Angerer, TB; Harreither, E; Aichinger, C; Micutkova, L; Jansen-Dürr, P; Grillari-Voglauer, R; Breitenbach, M; Wilson, IB; Breitenbach-Koller, L; Grillari, J

      Event: 2012 CSHL Meeting on Molecular Genetics of Aging

    • Year: 2012 -  High levels of onco-miR-21 contribute to a senescence-like growth arrest in normal human endothelial cells and fibroblasts

      Autoren: Wieser, M; Gruber, F; Tschachler, E; Grillari-Voglauer, R; Grillari, J

      Event: 42nd Annual Meeting of the European Society for Dermatological Research ESDR 2012

    • Year: 2011 -  Profiling of microRNA transcription during batch cultivation of CHO-K1 cells.

      Autoren: Hackl, M., Bort, JA., Jadhav, V., Harreither, E., Grillari, J., Borth, N.

      Event: 22nd meeting of the European Society for Animal Cell Technology ESACT 2011

    • Year: 2011 -  Endothelially secreted miRNA-31 inhibts osteogenic differentiation

      Autoren: Grillari J., Grillari R., Schraml E.

      Event: RNAi & miRNA world congress 2011

    • Year: 2011 -  Chinese Hamster Ovary (CHO) cell transcription profiling reveals the role of c-Myc and the mR-17-92 cluster in cellular physiology

      Autoren: Jadhav Vaibhav, Hackl Matthias, Hernandez Juan, Grillari Johannes, Borth Nicole

      Event: 40th Keystone Symposia 2011 - MicroRNAs and Non-Coding RNAs and Cancer joint with MicroRNAs and Human Disease

    • Year: 2011 -  Establishment of a large scale functional screening method for microRNAs in Chinese hamster ovary cells

      Autoren: Hackl Matthias, Jadhav Vaibhav, Borth Nicole, Wieser Matthias, Harreither Eva, Grillari Johannes

      Event: 22nd meeting of the European Society for Animal Cell Technology ESACT 2011

    • Year: 2011 -  Endothelially secreted miRNA-31 inhibts osteogenic differentiation

      Autoren: Grillari J.

      Event: 22nd meeting of the European Society for Animal Cell Technology ESACT 2011

    • Year: 2011 -  Next-generation sequencing of the Chinese hamster ovary microRNA transcriptome: identification, annotation and profiling of miRNA as targets for cellular engineering.

      Autoren: Hackl, M., Jakobi, T., Blom, J., Doppmeier, D., Brinkrolf, K., Szczepanowski, R., Bernhart, S., Höner zu Siederdissen, C., Bort, JA., Wieser, M., Kunert, R., Jeffs, S., Hofacker, I., Goesmann, A., Pühler, A., Borth, N, Grillari, J.

      Event: 22nd meeting of the European Society for Animal Cell Technology ESACT 2011

    • Year: 2011 -  From molecular biology of aging to production of recombinant proteins

      Autoren: Grillari J.

      Event: Departement Seminar in Paula Alves Lab 2011

    • Year: 2011 -  ATM-dependent phosphorylation of SNEV/hPrp19/hPso4 at S149 in oxidative stress, DNA repair and life span regulation

      Autoren: Hanna Dellago, Abdulhameed Khan, Monika Nussbacher, Christoph Mück, Pidder Jansen-Dürr, Regina Voglauer-Grillari and Johannes Grillari1

      Event: Current Trends in Biomedicine Workshop 2011 - Endogenous DNA damage as a source of cancer and aging

    • Year: 2011 -  Urine as a source for the generation of pluripotent stem cells

      Autoren: Grillari R, Zhou T, Benda C, Dunzinger S, Huang Y, Li X, Li Y, Guo X, Gao G, Chen S, Hao L, Chan YC, Ng KM, Ho JC, Wu J, Redl H, Tse HF, Wieser M, Grillari J, Pei D, Esteban M

      Event: 22nd meeting of the European Society for Animal Cell Technology ESACT 2011

    • Year: 2011 -  Endothelially secreted miR-31 inhibts osteogenic differentiation

      Autoren: Grillari J.

      Event: Berzelius Symposium 85 2011 - Telomere Biology in Healh and Disease - a crytal ball for the future?

    • Year: 2011 -  CHO miRNomics: small RNAs with big future in CHO cell line development

      Autoren: Hackl Matthias, Jadhav Vaibhav, Hernandez-Bort Juan-Antonio, Borth Nicole, Grillari Johannes

      Event: Optimizing Cell Line Performance Summit 2011

    • Year: 2011 -  Establishment of a large scale functional screening method for microRNAs in Chinese hamster ovary cells

      Autoren: Hackl M., Jadhav V., Borth N., Grillari J.

      Event: 22nd meeting of the European Society for Animal Cell Technology ESACT 2011

    • Year: 2011 -  Transcriptional profiling of optimized CHO host cell lines

      Autoren: Eva Harreither, Matthias Hackl, Johannes Pichler, Vaibhav Jadhav, Juan A. Hernandez-Bort, Helga Höflmyer, Johannes Grillari and Nicole Borth

      Event: 22nd meeting of the European Society for Animal Cell Technology ESACT 2011

    • Year: 2011 -  Endothelially secreted miRNA-31 inhibts osteogenic differentiation

      Autoren: Grillari J.

      Event: Berzelius Symposium 85 2011 - Telomere Biology in Healh and Disease - a crytal ball for the future?

    • Year: 2011 -  Endothelially secreted miRNA-31 inhibts osteogenic differentiation

      Autoren: Grillari J., Grillari R., Schraml E.

      Event: 7th International Association of Gerontology and Geriatrics IAGG European Region Congress 2011 - Healthy and Active Ageing for All Europeans II

    • Year: 2011 -  miRNAs in aging

      Autoren: Grillari J., Grillari R., Schraml E.

      Event: RNAi 2011 - Gene regulation by small RNAs

    • Year: 2011 -  Endothelially secreted miR-31 inhibts osteogenic differentiation

      Autoren: Grillari Johannes, Grillari Regina, Schraml Elisabeth

      Event: 40th Keystone Symposia 2011 - MicroRNAs and Non-Coding RNAs and Cancer joint with MicroRNAs and Human Disease

    • Year: 2011 -  Endothelially secreted miR-31 inhibits osteogenic differentiation

      Autoren: Grillari J.

      Event: 22nd meeting of the European Society for Animal Cell Technology ESACT 2011

    • Year: 2011 -  Endothelially secreted miRNA-31 inhibts osteogenic differentiation

      Autoren: Grillari J.

      Event: 7th International Association of Gerontology and Geriatrics IAGG European Region Congress 2011 - Healthy and Active Ageing for All Europeans II

    • Year: 2011 -  A role of miRNAs in Aging

      Autoren: Grillari J.

      Event: 41st European Society of Dermatological Research meeting 2011

    • Year: 2011 -  Endothelially secreted miRNA-31 inhibts osteogenic differentiation

      Autoren: Grillari J., Grillari R., Schraml E.

      Event: 7th International Association of Gerontology and Geriatrics IAGG European Region Congress 2011 - Healthy and Active Ageing for All Europeans II

    • Year: 2010 -  Micro RNAs - small RNAs with big future in Chinese Hamster Ovary cell culture technology

      Autoren: Hackl M, Brinkrolf K, Szczepanowski R, Pühler A, Grillari J, Borth N

      Event: EAPB Science to Market Conference 2010

    • Year: 2010 -  Tauchen im Jungbrunnen: Möglichkeiten und Grenzen der biologischen Altersforschung

      Autoren: Grillari Johannes

      Event: Volkshochschule Brigittenau 2010

    • Year: 2010 -  miRNAs in aging

      Autoren: Grillari J., Grillari R., Schraml E.

      Event: BSAR and CISBAN meeting

    • Year: 2010 -  miRNAs in endothelial cell senescence

      Autoren: Grillari J.

      Event: Departmental Seminar

    • Year: 2010 -  Deep Sequencing of CHO microRNAs as prerequisite for a novel approach to CHO cell engineering

      Autoren: Hackl M., Brinkrolf K., SzczepanowskiR., , Pühler A., Borth N., Grillari J.

      Event: 12th Cell Culture Engineering Conference 2010

    • Year: 2010 -  miRNAs as novel markers of human aging

      Autoren: Grillari J.

      Event: Departmental Seminar, Calogero Caruso Lab

    • Year: 2010 -  Nopsi is a novel conserved lifespan modulator of C. elegans

      Autoren: Fuchs, E; Schosserer, M; Linder, A; Wilson, IBH; Grillari-Voglauer, R; Grillari, J

      Event: 2nd ÖGMBT Annual Meeting 2010

    • Year: 2010 -  miRNAs in tissue regeneration and aging

      Autoren: Grillari J., Wieser M.

      Event: Non-coding RNA

    • Year: 2010 -  From molecular biology of aging to production of recombinant proteins

      Autoren: Grillari J., Grillari R., Schraml E.

      Event: Laupheimer Zelltage 2010 - Zellfabriken der Zukunft

    • Year: 2010 -  miRNAs as novel markers of human aging

      Autoren: Grillari J.

      Event: Departmental Seminar, Rudi Westendorp Lab

    • Year: 2010 -  miRNAs as novel tools for CHO cell engineering: sequencing, profiling and first functional insights

      Autoren: Grillari J.

      Event: IBC/Informa Life Sciences, Cell Line Development and Engineering Conference 2010

    • Year: 2010 -  The novel RNA-methyl-transferase Nopsi modulates the lifespan of model organisms

      Autoren: Schosserer, M; Minois, N; Fuchs, E; Linder, A; Sekot, G; Grillari-Voglauer, R; Wilson, I; Grillari J

      Event: FEBS/SFRR-E/IUBMB Advanced Lecture Course "Protein maintenance and turnover in ageing & diseases

    • Year: 2010 -  miRNAs in endothelial cell senescence

      Autoren: Grillari J.

      Event: WhyWeAge Workshop 2010 - Vascular Aging

    • Year: 2010 -  Determination of FZD3 as a direct target of miR-31 in Osteogenic Differentiating Adipose-tissue derived Stem Cells (ASCs)

      Autoren: Schneider K. H., Wassermann K. J., Schraml E., Wieser M., Grillari-Voglauer R., Redl H., Grillari J

      Event: 2nd ÖGMBT Annual Meeting 2010

    • Year: 2010 -  The novel RNA-methyl-transferase Nopsi modulates the lifespan of Drosophila melanogaster

      Autoren: Schosserer, M; Minois, N; Bakowska-Zywicka, K; Fuchs, E; Sekot, G; Grillari-Voglauer, R; Polacek, N; Grillari, J

      Event: 2nd ÖGMBT Annual Meeting 2010

    • Year: 2010 -  Endothelially sectred miRNA-31 inhibits osteogenix differentation

      Autoren: Grillari J., Grillari R., Schraml E.

      Event: Gordon conference on Molecular Biology of Aging 2010

    • Year: 2010 -  Exo70, a Subunit of the Exocyst Complex, Interacts with SNEVhPrp19/hPso4 and Is Involved in Pre-mRNA Splicing

      Autoren: Hanna Dellago, Marlies Löscher, Anna Gstraunthaler, Regina Grillari-Voglauer, Klaus Fortschegger, and Johannes Grillari

      Event: 2nd ÖGMBT Annual Meeting 2010

    • Year: 2010 -  Molecular Characteristics of CHO Host Cell Lines Optimised by Cell Sorter Assisted Directed Evolution.

      Autoren: Borth N., Pichler J., Hernandez Bort J.A., Hackl M., Höflmayer H., Grillari J.

      Event: 12th Cell Culture Engineering Conference 2010

    • Year: 2010 -  Faconi Anemia complex members and telomere dependent senescence

      Autoren: Grillari J., Weilner S., Grillari R., Wieser M.

      Event: Traute Schroeder-Kurth Symposium

    • Year: 2010 -  Molecular Characteristics of CHO Host Cell Lines Optimised by Cell Sorter Assisted Directed Evolution

      Autoren: Borth N., Hernandez Bort J.A., Hackl M., Höflmayer H., Pichler J., Grillari J.

      Event: JAACT Meeting 2010

    • Year: 2009 -  MicroRNAs as novel tools for CHO cell engineering: profiling of differential microRNA expression and first regulatory insights

      Autoren: Hackl M., Müller D., Borth N., Grillari J.

      Event: 21st Meeting of the European Society for Animal Cell Technology ESACT 2009

    • Year: 2009 -  MicroRNAs as novel tools for CHO cell engineering: profiling of differential microRNA expression and first regulatory insights

      Autoren: Hackl M., Müller D., Borth N., Grillari J.

      Event: 1st Annual Meeting of the Austrian Association of Molecular Life Sciences and Biotechnology ÖGMBT 2009

    • Year: 2009 -  Prolonging the life span: SNEV and NOPSI

      Autoren: Grillari J.

      Event: 1st Annual Meeting of the Austrian Association of Molecular Life Sciences and Biotechnology ÖGMBT 2009

    • Year: 2009 -  Exo70, a subunit of the exocyst complex, is involved in pre-mRNA splicing

      Autoren: Dellago H, Löscher M, Ajuh P, Ryder U, Kaisermayer C, Grillari-Voglauer R, Fortschegger K, Gross S, Gstraunthaler A, Borth N, Eisenhaber F, Lamond AI, Grillari J.

      Event: 1st Annual Meeting of the Austrian Association of Molecular Life Sciences and Biotechnology ÖGMBT 2009

    • Year: 2009 -  miRNAs are secreted by senescent endothelial cells

      Autoren: Schraml E., Fortschegger K., Wieser M., Grillari R., Grillari J.

      Event: Kick-off meeting of GEN-AU 2009

    • Year: 2009 -  HIV-1 induces telomerase activity in macrophages.

      Autoren: Reynoso R., Wieser M., Bolcic F., Sabatté J., Kühnel H., Salomón H., Grillari J., Katinger H., Grillari-Voglauer R., Quarleri J.

      Event: 1st Annual Meeting of the Austrian Association of Molecular Life Sciences and Biotechnology ÖGMBT 2009

    • Year: 2009 -  Die Rolle der Endothelzelle bei altersassoziierten Erkrankungen

      Autoren: Grillari J.

      Event: Menopause, Andropause, and Anti-Aging 2009

    • Year: 2009 -  MicroRNA expression profiling identifies miR-17 and miR-19b as commonly downregulated in replicative and chronological human aging models

      Autoren: Hackl M., Brunner S., Fortschegger K., Schreiner C., Micutcova L., Wieser M., Laschober G., Lepperdinger G., Sampson N., Berger P., Herndler-Brandstätter D., Kühnel H., Strasser A., Breitenbach M., Rinnerthaler M., Eckhard L., Tschachler E., Paar C., Scheideler M., Trajanoski Z., Grillari-Voglauer R., Grubeck-Loebenstein B., Jansen-Dürr P., and Grillari J.

      Event: Biomarkers of Ageing: from Molecular Biology to Clinical Perspectives 2009

    • Year: 2009 -  The novel protein Nopsi elongates the life span of model organisms

      Autoren: Schosserer M, Minois N, Linder A, Wilson I, Sekot G, Wurzenberger J, Katinger H, Grillari-Voglauer R, Grillari J.

      Event: 1st Annual Meeting of the Austrian Association of Molecular Life Sciences and Biotechnology ÖGMBT 2009

    • Year: 2009 -  Baden im Jungbrunnen: Möglichkeiten und Grenzen der biologischen Altersforschung

      Autoren: Grillari Johannes

      Event: Volkshochschule Nord-West Alsergrund 2009

    • Year: 2009 -  Exo70, a subunit of the exocyt complex, is involved in pre-mRNA splicing

      Autoren: Dellago H., Löscher M., Ajuh P., Ryder U., Kaisermayer C., Grillari R., Fortschegger K., Gross S., Borth N., Einsenhaber F., Lamond A.I., Grillari J.

      Event: 1st Annual Meeting of the Austrian Association of Molecular Life Sciences and Biotechnology ÖGMBT 2009

    • Year: 2008 -  SNEV is a multitalented protein involved in aging

      Autoren: Grillari, J.

      Event: Seminars at Insitute of Biomedical Research, Innsbruck, Austria

    • Year: 2008 -  Nopsi is a novel SNEV interacting protein involved in regulation of organismal life span

      Autoren: Schosserer, M; Minois, N; Linder, A; Löscher, M; Wilson, IBH; Voglauer-Grillari, R; Grillari, J

      Event: 6th European Congress of Biogerontology 2008

    • Year: 2008 -  Exo70, a subunit of the exocyst complex: A possible link between vesicular transport, pre-mRNA splicing and aging?

      Autoren: Dellago H., Löscher M., Ajuh P., Ritter G., Eisenhaber F., Lamond A. I., Katinger H., Voglauer-Grillari R., and Grillari J.

      Event: International Symposium on Neurobiology and Neuroendocrinology of Aging

    • Year: 2008 -  Biology of Aging

      Autoren: Grillari, J.

      Event: Diplomkurs - Geriatrie, Österreichische Ärztekammer 2008

    • Year: 2008 -  Identification of miRNAs involved in replicative senescence of human umbilical vein endothelial cells

      Autoren: Grillari J., Wieser M., Fortschegger K., Schreiner C., Grillari R.

      Event: RNAi Synopsium Applied Biosystems 2008

    • Year: 2008 -  Prolonging the "health span" by altering the expression of single genes

      Autoren: Grillari J.

      Event: Menopause - Andropause - Anti-Aging 2008

    • Year: 2008 -  Acute adrenergic stress inhibits proliferation of murine haematopoietic progenitor cells via p38/MAPK signalling.

      Autoren: Schraml E., Fuchs R., Kotzbeck P., Grillari J. and Schauenstein K.

      Event: 9th International Symposium on Neurobiology and Neuroendocrinology of Aging 2008

    • Year: 2008 -  Exo70, a subunit of the exocyst complex: A possible link between vesicular transport, pre-mRNA splicing and aging?

      Autoren: Hanna Dellago, Marlies Löscher, Paul Ajuh, Gustav Ritter, Frank Eisenhaber, Angus Lamond, Hermann Katinger, Regina Grillari and Johannes Grillari.

      Event: 9th International Symposium on Neurobiology and Neuroendocrinology of Aging 2008

    • Year: 2008 -  Prolonging the "health span" by altering the expression of single genes.

      Autoren: Grillari, J.

      Event: Menopause - Andropause - Anti-Aging 2008

    • Year: 2008 -  The novel protein Nopsi and its impact on the life span of Drosophila melanogaster

      Autoren: Schosserer, M; Minois, N; Linder, A; Sekot, G; Katinger, H; Grillari-Voglauer, R; Grillari, G

      Event: Joint Annual Meeting of ÖGBM, ÖGGGT, ÖGBT and ANGT Life Science 2008

    • Year: 2007 -  Chasing the Substrate(s) of the E3 Ubiquitin Ligase SNEVPrp19/Pso4

      Autoren: Dellago H., Raffetseder J., Pokar M., Kus B., Rotin D., Katinger H., Voglauer R., and Grillari J.

      Event: 12th Congress of the International Association of Biomedical Gerontology IABG 2007 - Molecular Mechanisms and Models of Aging

    • Year: 2007 -  The endothelial cell as model system for aging research

      Autoren: Grillari J.

      Event: Sitzung der Österreichischen Gesellschaft für Geriatrie und Gerontologie und des Ludwig Boltzmann-Institutes für Alternsforschung 2007

    • Year: 2007 -  Establishment of continuously growing human adult stem cell lines for cell-based therapies

      Autoren: Voglauer, R.; Stadler, G.; Gillich, A.; Karbiener, M.; Wieser, M.; Brunauer, R.; Lepperdinger, G.; Grillari, J.; Redl, H.; Katinger, H.; Peterbauer, A.; Wolbank, S.

      Event: 2nd Annual European Cell Line Development and Engineering 2007

    • Year: 2007 -  Role of miRNAs in Replicative Senescence of Endothelial Cells

      Autoren: Fortschegger K., Wieser M., Schreiner C., Katinger H., Voglauer R., and Grillari J.

      Event: 32nd Congress of the Federation of European Biochemical Societies FEBS 2007 - Molecular Machines

    • Year: 2007 -  TRACKING THE SUBSTRATE(S) OF THE E3 UBIQUITIN LIGASE SNEV/PRP19/PSO4

      Autoren: Dellago H, Kus B, Rotin D, Pokar M, Voglauer R, Katinger H and Grillari J.

      Event: 32nd Congress of the Federation of European Biochemical Societies FEBS 2007 - Molecular Machines

    • Year: 2007 -  CHASING THE SUBSTRATE(S) OF THE E3 UBIQUITIN LIGASE SNEVPRP19/PSO4

      Autoren: Hanna Dellago, Bart Kus, Daniela Rotin, Marion, Pokar, Regina Voglauer, Hermann Katinger and Johannes Grillari

      Event: 12th Congress of the International Association of Biomedical Gerontology IABG 2007 - Molecular Mechanisms and Models of Aging

    • Year: 2007 -  Blom7 alpha is a novel protein interacting with RNA, the telomere and the replicative senescence-related proteins SNEV and Hic-5

      Autoren: Schosserer, M; Lee, K; Löscher, M; Ajuh, P; Denegri, M; Lamond, AI; Katinger, H; Voglauer, R; Grillari, J

      Event: 12th Congress of the International Association of Biomedical Gerontology IABG 2007 - Molecular Mechanisms and Models of Aging

    • Year: 2007 -  Immortalization and characterization of human adipose tissue derived stem cells

      Autoren: Karbiener M, Gillich A, Wolbank S, Stadler G, Redl H, Katinger H, Grillari J, Grillari R

      Event: Ludwig Boltzmann Institut für experimentelle und klinische Traumatologie 2007

    • Year: 2007 -  Immortalization and characterization of human amnion tissue derived stem cells

      Autoren: Gillich Q, Karbiener M, Wolbank S, Stadler G, Redl H, Katinger H, Grillari J, Grillari R

      Event: Ludwig Boltzmann Institut für experimentelle und klinische Traumatologie 2007

    • Year: 2007 -  Identification of miRNAs involved in replicative senescence of human endothelial cells

      Autoren: Fortschegger K., Wieser M., Schreiner C., Katinger H., Voglauer R., and Grillari J.

      Event: Gordon conference Molecular Biology of Aging 2007

    • Year: 2006 -  Role of miRNAs in Replicative Senescence of Endothelial Cells

      Autoren: Fortschegger, K.; Wieser, M.; KAtinger, H.; Voglauer, R.; Grillari, J.

      Event: GEN-AU conference 2006 - Genomics for Health

    • Year: 2006 -  The expression of  PRP19/PSO4, the mouse homologue of  human senescence evasion factor (SNEV), is associated with self-renewal of murine hematopoietic stem cells

      Autoren: Schraml, E.; Schwarzenberger, E.; Fortschegger, K.; Voglauer, R.; Grillari, J.; Schauenstein, K.

      Event: European Conference on Aging ECONAG 2006

    • Year: 2006 -  Alternsforschung: Tauchen im Jungbrunnen?

      Autoren: Grillari, J.

      Event: Uni Goes Popper

    • Year: 2006 -  Identification of BLOM7a, a putative RNA-binding protein, as potential coactivator for p21 and c-fos

      Autoren: Lee, K.; Löscher, M.; Katinger, H.; Voglauer, R.; Grillari, J.

      Event: Annual Meeting of the ÖGBM, ÖGGGT, ÖGBT & ANGT - Life Science 2006

    • Year: 2006 -  Early embryonic lethality of mice lacking SNEV (Prp19/Pso4/NMP200)

      Autoren: Fortschegger, K.; Wagner, B.; Voglauer, R.; Katinger, H.; Sibilia, M.; Grillari, J.

      Event: Annual Meeting of the ÖGBM, ÖGGGT, ÖGBT & ANGT - Life Science 2006

    • Year: 2006 -  SNEV is a multifunctional protein involved in aging

      Autoren: Grillari, J.; Katinger, H.; Voglauer, R.

      Event: University of Tübingen

    • Year: 2006 -  A high troughput screening to identify substrates for the ubiquitin ligase SNEV/Prp19 (Poster)

      Autoren: Hanna Dellago, Johanna Raffetseder, Bart Kuss, Daniela Rotin, Hermann Katinger, Johannes Grillari

      Event: Annual Meeting of the ÖGBM, ÖGGGT, ÖGBT & ANGT - Life Science 2006

    • Year: 2006 -  Early embyronic lethality of mice lacking SNEV (Prp19/Pso4/NMP200)

      Autoren: Fortschegger, K.; Wagner, B.; Voglauer, R.; Katinger, H.; Sibilia, M.; Grillari, J.

      Event: European Conference on Aging ECONAG 2006

    • Year: 2006 -  Characterization of novel proteins involved in replicative senescence

      Autoren: Grillari J., Linder A., Siena E., Fortschegger K., Löscher M., Katinger H., and Voglauer R.

      Event: Forum für Geriatrie

    • Year: 2006 -  Towards identification of RNA motifs bindnig to Blom7alpha using SELEX and their possible biological function

      Autoren: Löscher, M.; Dausse, E.; Toulme, J.; Katinger, H.; Grillari, J.

      Event: Annual Meeting of the ÖGBM, ÖGGGT, ÖGBT & ANGT - Life Science 2006

    • Year: 2006 -  Getting insights into the interaction between SNEVPrp19 and WRN

      Autoren: Strauss, M.; Wieser, M.; Denegri, M.; Fortschegger, K.; Katinger, H.; Grillari, J., Voglauer, R.

      Event: Annual Meeting of the ÖGBM, ÖGGGT, ÖGBT & ANGT - Life Science 2006

    • Year: 2006 -  The quest for SNEV‘s target: Purification and identification of differentially ubiquitinated proteins

      Autoren: Pokar, M.; Voglauer, R.; Katinger, H.; Grillari, J.

      Event: Annual Meeting of the ÖGBM, ÖGGGT, ÖGBT & ANGT - Life Science 2006

    • Year: 2006 -  SNEV/Prp19/Pso4 is a multifunctional protein involved in the regulation of the replicative life span of human endothelial cells

      Autoren: Grillari, J.; Chang, M.; Fortschegger, K.; Löscher, M.; Stadler, G.; Wieser, M.; Ajuh,P.; Lamond, A.; Katinger, H.; Voglauer, R.

      Event: European Conference on Aging ECONAG 2006

    • Year: 2006 -  Biological variation versus common mechanisms of cellular senescence using HUVECs as model: a new application of proteomics

      Autoren: Chang, M.W.; Voglauer, R.; Hirschmann, J.; Fortschegger, K.; Allmaier, G.; Strelec, H.; Katinger, H.; Grillari, J.

      Event: European Conference on Aging ECONAG 2006

    • Year: 2006 -  Cellular senescence and immortalization of renal proximal tubular epithelial cells

      Autoren: Wieser, M.; Stadler, G.; Hofer, D.; Grillari, J.; Katinger, H.; Voglauer R.

      Event: European Conference on Aging ECONAG 2006

    • Year: 2006 -  Identification of endogenous RNA interacting with the novel protein Blom7a

      Autoren: Schosserer, M; Löscher, M; Dausse, E; Toulme, JJ; von Pelchrzim, F; Schröder, R; Katinger, H; Grillari, J

      Event: Annual Meeting of the ÖGBM, ÖGGGT, ÖGBT & ANGT - Life Science 2006

    • Year: 2006 -  A high troughput screening to identify substrates for the ubiquitin ligase SNEV/Prp19

      Autoren: Dellago, H.; Raffetseder, J.; Kus, B.; Rotin, D.; Katinger, H.; Grillari, J.

      Event: Annual Meeting of the ÖGBM, ÖGGGT, ÖGBT & ANGT - Life Science 2006

    • Year: 2005 -  Tauchen im Jungbrunnen: Möglichkeiten und Grenzen der biologischen Alternsforschung.

      Autoren: Grillari, J.

      Event: Vortragsreihe des Gesundheits- und Sozialsprengel Tirol

    • Year: 2005 -  Early embryonic lethality of knock-out mice lacking the essential pre-mRNA-splicing factor SNEV (Poster)

      Autoren: Fortschegger, K., Wagner, B., Voglauer, R., Katinger, H., Sibilia, M., Grillari, J.

      Event: 60 Year Anniversary, Institute of Applied Microbiology IAM 2005

    • Year: 2005 -  Overexpression of SNEV correlates with enhanced DNA damage repair capacity in human endothelial cells (Poster)

      Autoren: Voglauer, R., Chang, M., Dampier, B., Wieser, M., Baumann, K., Hofer, D., Sterovsky, T., Schreiber, M., Katinger, H., Grillari, J.

      Event: 60 Year Anniversary, Institute of Applied Microbiology IAM 2005

    • Year: 2005 -  Art DECO: The art to find a needle in the haystack

      Autoren: Chang, M., Hemetsberger, T., Marzban, G., Katinger, H., Grillari, J.

      Event: 2nd International Symposium of the Austrian Proteomics Platform 2005

    • Year: 2005 -  When cells get old: Identification and characterization of proteins involved in cellular aging (Poster)

      Autoren: Grillari, J., Katinger, H.

      Event: 60 Year Anniversary, Institute of Applied Microbiology IAM 2005

    • Year: 2005 -  Ectopic hTERT expression-Eternal youth for endothelial cells.

      Autoren: Chang, M., Grillari, J., Mayrhofer, C., Fortschegger, K., Allmaier, G., Marzban, G., Katinger, H., Voglauer, R.

      Event: Telomeres & Telomerase 2005

    • Year: 2005 -  Characterization of proteins involved in replicative senescence and immortalization

      Autoren: Voglauer, R., Katinger, H., Grillari J.

      Event: Unknown

    • Year: 2005 -  Telomere attrition and ROS dynamica in renal tubular epithelial cells

      Autoren: Wieser M, Stadler G, Hofer D, Katinger H, Grillari J, Grillari R

      Event: Life Sciences 2005, Joint Annual Meeting of ÖGBM, ÖGGGT, ÖGBT and ANGT

    • Year: 2005 -  Woher weiß eine humane Zelle, wie alt sie ist?

      Autoren: Grillari, J.

      Event: Bundesgymnasium Lienz

    • Year: 2005 -  Protein profiling of human blood platelets from young and old individuals

      Autoren: Zellner, M., Winkler, W., Garo, F., Miller, I., Chang, M., Grillari, J., Rappold, E., Öehler, R.

      Event: 2nd International Symposium of the Austrian Proteomics Platform 2005

    • Year: 2005 -  Characterization of the novel protein Nopsi (WBSCR20A) (Poster)

      Autoren: Siena, E., Lee, K., Löscher, M., Katinger, H., Voglauer, R., Grillari, J.

      Event: Life Sciences 2005, Joint Annual Meeting of ÖGBM, ÖGGGT, ÖGBT and ANGT

    • Year: 2005 -  From gene to monoclonal antibody: efficient screening by cell sorting

      Autoren: Borth N., Böhm E., Grillari J., Löscher M., Gross S., Voglauer R., Ferko B., Kunert R., Katinger H.

      Event: Animal Cell Technology meets Genomics

    • Year: 2005 -  Woher weiß die Zelle wie alt sie ist?

      Autoren: Grillari Johannes

      Event: Bundesgymnasium Lienz

    • Year: 2005 -  Changes of the "ubiquitinome" during cellular ageing (Poster)

      Autoren: Pokar, M., Voglauer, R., Katinger, H., Grillari, J.

      Event: Life Sciences 2005, Joint Annual Meeting of ÖGBM, ÖGGGT, ÖGBT and ANGT

    • Year: 2005 -  Establishment of a continuously growing fibroblast cell line derived from a Williams-Beuren syndrome patient (Poster)

      Autoren: Linder, A., Wieser, M., Katinger, H., Grillari, J., Voglauer, R.

      Event: Life Sciences 2005, Joint Annual Meeting of ÖGBM, ÖGGGT, ÖGBT and ANGT

    • Year: 2005 -  Intracellular H2O2 level declines with age in renal tubular epithelial cells (Poster)

      Autoren: Wieser, M., Stadler, G., Grillari, J., Katinger, H., Voglauer, R.

      Event: 60 Year Anniversary, Institute of Applied Microbiology IAM 2005

    • Year: 2005 -  Identification of BLOM7alpha, a putative RNA-binding protein, as androgen receptor and p21 coactivator (Poster)

      Autoren: Lee, K., Löscher, M., Miehl, T., Ritter, G., Klocker, H., Katinger, H., Voglauer, R., Grillari, J.

      Event: Life Sciences 2005, Joint Annual Meeting of ÖGBM, ÖGGGT, ÖGBT and ANGT

    • Year: 2005 -  Cellular Senescence (oral presentation)

      Autoren: Grillari, J.

      Event: 60 Year Anniversary, Institute of Applied Microbiology IAM 2005

    • Year: 2005 -  hExo70, a subunit of the exocyst complex, links vesicle transport to pre-mRNA splicing

      Autoren: Grillari, J., Löscher, M., Ajuh, P., Voglauer, R., Fortschegger, K., Eisenhaber, F., Lamond, A.I., Katinger, H.

      Event: RNA 2005

    • Year: 2005 -  Overexpression of SNEV extends the replicative lifespan of normal human endothelial cells in vitro.

      Autoren: Voglauer, R., Chang, M., Wieser, W., Fortschegger, K., Baumann, K., Katinger, H., Grillari, J.

      Event: Telomeres & Telomerase 2005

    • Year: 2005 -  Overexpression of SNEV extends the replicative life-span of human endothelial cells in vitro (oral presentation)

      Autoren: Voglauer, R., Chang, M., Wieser, M., Fortschegger, K., Baumann, K., Katinger, H., Grillari, J.

      Event: Analysis of Microbial Cells at the Single Cell Level 2005

    • Year: 2005 -  From Gene to antibody: efficient screening by cell sorting.

      Autoren: Ernst Böhm, Johannes Grillari, Martina Löschel, Stefan Gross, Regina Voglauer, Renate Kunert, Hermann Katinger, Nicole Borth

      Event: 60 Year Anniversary, Institute of Applied Microbiology IAM 2005

    • Year: 2005 -  Large scale analysis of the CDC5L complex in HeLa nuclear extracts

      Autoren: Ajuh, P., Pilch, B., Lleres, D., Grillari, J., Mann, M., Lamond, A.I.

      Event: RNA 2005

    • Year: 2005 -  SNEV, Blom7 and replicative senescence

      Autoren: Grillari, J.

      Event: Seminars at Inserm

    • Year: 2005 -  Does the novel protein Blom7 induce cell cycle arrest? (Poster)

      Autoren: Miehl, T., Lee, K., Katinger, H., Grillari, J., Voglauer, R.

      Event: Life Sciences 2005, Joint Annual Meeting of ÖGBM, ÖGGGT, ÖGBT and ANGT

    • Year: 2004 -  Characterization of endothelial cells overexpressing SNEV

      Autoren: Baumann, K., ,Grillari, J., Wieser, M., Stadler, G., Fortschegger, K., Chang, M., Katinger, H., Voglauer, R.

      Event: Joint Annual Meeting of the ÖGBM, ÖGGGT, ÖGBT and ANGT 2004

    • Year: 2004 -  Expression profiling of young, senescent and immortalized cell lines

      Autoren: Edtmayer, M., Fortschegger, K., Voglauer, R., Wieser, M., Chang, M., Sommergruber, W., Katinger, H., Grillari, J.

      Event: Joint Annual Meeting of the ÖGBM, ÖGGGT, ÖGBT and ANGT 2004

    • Year: 2004 -  Generation of CD4+ CTLs Ex Vivo

      Autoren: Jursik, C., Prchal, M., Voglauer, R., Grillari, J., Hemetsberger, T., Katinger, H.

      Event: 6th International Conference on New Trends in Immunosuppression 2004

    • Year: 2004 -  Screening for protein-protein interaction partners of SKIP, a component of the human spliceosome

      Autoren: Schörgenhumer, F., Loescher, M., Katinger, H., Grillari, J.

      Event: Joint Annual Meeting of the ÖGBM, ÖGGGT, ÖGBT and ANGT 2004

    • Year: 2004 -  Comparison of protein profiles of different CHO cell lines

      Autoren: Przewalla, C., Chang, M., Kunert, R., Hesse, F., Grillari, J., Borth, N., Katinger, H.

      Event: 6th Siena meeting from genome to proteome 2004 - Biomarker discovery and proteome imaging

    • Year: 2004 -  Protein expression profiling of human endothelial cells during in vitro aging: Does sex have an influence?

      Autoren: Chang, M., Voglauer, R., Gruber, V., Katinger, H., Grillari, J.

      Event: 6th Siena meeting from genome to proteome 2004 - Biomarker discovery and proteome imaging

    • Year: 2004 -  The novel protein Blom7 is a transcriptional co-activator

      Autoren: Voglauer, R., Löscher, M., Dampier, B., Eisenhaber, F., Klocker, H., Lamond, A., Schreiber, M., Katinger, H., Grillari, J.

      Event: Joint Annual Meeting of the ÖGBM, ÖGGGT, ÖGBT and ANGT 2004

    • Year: 2004 -  SNEV, a multifaceted protein involved in regulation of cellular life span, is a splicing factor

      Autoren: Grillari, J., Ajuh, P., Stadler, G., Löscher, M., Lamond, A.I., Katinger, H.

      Event: RNA 2004

    • Year: 2004 -  The U-box E3 Ligase SNEV interacts with the 7 subunit of the 20 S proteasome

      Autoren: Löscher, M., Fortschegger, K., Voglauer, R., Schmid, J., Katinger, H., Grillari, J.

      Event: Joint Annual Meeting of the ÖGBM, ÖGGGT, ÖGBT and ANGT 2004

    • Year: 2004 -  Platelet proteomics: A tool to analyse age-related changes in the protein expression profile

      Autoren: Zellner, M., Winkler, W., Miller, I., Chang, M., Grillari, J., Oehler, R.

      Event: 1st International Symposium of the Austrian Proteomics Platform 2004

    • Year: 2004 -  Protein expression profiling of human endothelial cells during in vitro aging: does sex have an influence?

      Autoren: Chang M, Grillari R, Schiller D, Kopec A, Gruber V, Katinger H, Grillari J

      Event: 2. Österreichisches Proteomforschungssymposium 2004

    • Year: 2004 -  Early embryonic lethality of mice lacking SNEV (NMP200/Prp19/PSO4)

      Autoren: Fortschegger, K., Sibilia, M., Wagner, B., Voglauer, R., Katinger, H., Grillari, J.

      Event: Joint Annual Meeting of the ÖGBM, ÖGGGT, ÖGBT and ANGT 2004

    • Year: 2004 -  Protein expression profiling of human endothelial cells during in vitro aging: Does sex have an influence?

      Autoren: Schiller, D., Chang, M., Voglauer, R., Kopec, A., Gruber, V., Katinger, H., Grillari, J.

      Event: Joint Annual Meeting of the ÖGBM, ÖGGGT, ÖGBT and ANGT 2004

    • Year: 2004 -  hExo70, a subunit of the exocyst complex, links vesicular transport to pre-mRNA splicing

      Autoren: Grillari, J., Löscher, M., Ajuh, P., Ritter, G., Eisenhaber, F., Lamond, A., Katinger, H.

      Event: Joint Annual Meeting of the ÖGBM, ÖGGGT, ÖGBT and ANGT 2004

    • Year: 2004 -  The U-box E3 Ligase SNEV interacts with the 7 subunit of the 20 S proteasome

      Autoren: Löscher, M., Fortschegger, K., Voglauer, R., Schmid, J., Katinger, H., Grillari, J.

      Event: EMBO/Harden conference: Ubiquitin and proteasome system in health and disease

    • Year: 2004 -  Platelet proteomics: A tool to analyse age-related changes in the protein expression profile

      Autoren: Zellner, M., Winkler, W., Miller, I., Chang, M., Grillari, J., Staes, A., Hugelier, K., Vandekerckhove, J., Gevaert, K., Oehler, R.

      Event: 6th Siena meeting from genome to proteome 2004 - Biomarker discovery and proteome imaging

    • Year: 2004 -  Generation and characterization of polyclonal antibodies against the novel protein Blom7

      Autoren: Jakeli, S., Löscher, M., Zehentner, S., Ferko, B., Katinger, H., Grillari, J.

      Event: Joint Annual Meeting of the ÖGBM, ÖGGGT, ÖGBT and ANGT 2004

    • Year: 2003 -  Comparison of normal, senescent, and telomerase overexpressing endothelial cells by 2D- fluorescent –difference-in-gel-electrophoresis (DIGE)

      Autoren: Chang, M., Stadler, G., Marzban, G., Grillari, J., Voglauer, R., Katinger, H.

      Event: Proteomics: Present Perspectives & Future Challengers

    • Year: 2003 -  Domain mapping of protein-protein interactions of SNEV and its binding partners

      Autoren: Ritter, G., Löscher, M., Katinger, H., Grillari, J.

      Event: Joint Annual Meeting of the ÖGBM, ÖGGGT, ÖGBT and ANGT 2003

    • Year: 2003 -  Are telomerase overexpressing endothelial cells young? A proteomic approach using 2D-DIGE

      Autoren: Chang, M., Grillari, J., Mayrhofer, C., Katinger, H., Voglauer, R.

      Event: Thermo Electron Corporation and Amersham Biosciences Seminar Tour 2003

    • Year: 2003 -  SNEV: a multifaceted protein involved in replicative senescence, splicing, and the ubiquitin system

      Autoren: Grillari, J., Löscher, M., Chang, M., Fortschegger, K., Katinger, H., Voglauer, R.

      Event: Joint Annual Meeting of the ÖGBM, ÖGGGT, ÖGBT and ANGT 2003

    • Year: 2003 -  Platelet proteomics: a tool to analyse age-related changes in the protein expression profile

      Autoren: Zellner, M., Winkler, W., Chang, M., Grillari, J., Oehler R.

      Event: Proteomic Forum

    • Year: 2003 -  Comparison of young, senescent, and telomerase overexpressing endothelial cells

      Autoren: Chang, M., Stadler, G., Voglauer, R., Marzban, G., Katinger, H., Grillari, J.

      Event: Amersham workshop on differential in-gel electrophoresis

    • Year: 2003 -  A link between the ubiquitin mediated proteasomal degradation pathway and the splicing machinery

      Autoren: Löscher, M., Wostry, M., Katinger, H., Grillari, J.

      Event: Joint Annual Meeting of the ÖGBM, ÖGGGT, ÖGBT and ANGT 2003

    • Year: 2003 -  Establishment and characterization of CD4+ Killer-T-Cells (KTCS)

      Autoren: Voglauer, R., Jursik, C., Prchal, M., Jungfer, H., Grillari, J., Katinger, H.

      Event: 18th ESACT Meeting 2003 - Animal Cell Technology Meets Genomics

    • Year: 2003 -  Are telomerase overexpressing endothelial cells young? A proteomic approach using 2D-DIGE

      Autoren: Chang, M., Mayrhofer, C., Voglauer, R., Katinger, H., Grillari, J.

      Event: Proteomic Forum

    • Year: 2003 -  Efficient Selection of Antigen Specific Hybridomas by Cell Sorting using a Single Cell Secretion Assay

      Autoren: Borth N., Böhm E., Grillari J., Voglauer R., Kunert R., Gross S., Ferko B., Katinger H.

      Event: 18th ESACT Meeting 2003 - Animal Cell Technology Meets Genomics

    • Year: 2003 -  Expression profiling of young, senescent and immortalized cell lines

      Autoren: Edtmayer, M., Fortschegger, K., Wieser, M., Voglauer, R., Katinger, H., Grillari, J.

      Event: Joint Annual Meeting of the ÖGBM, ÖGGGT, ÖGBT and ANGT 2003

    • Year: 2003 -  SNEV and the proteasome

      Autoren: Grillari, J., Löscher, M., Stadler, G., Fortschegger, K., Chang, M., Voglauer, R., Gross, S., Sterovsky, T., Grabherr, R.M., Katinger, H.

      Event: 43. Österreichischer Geriatriekongress mit internationaler Beteiligung 2003

    • Year: 2003 -  Establishment and characterization of CD4+ Killer-T-cells (KTCs)

      Autoren: Voglauer, R., Jursik, C., Prchal, M., Jungfer, H., Grillari, J.

      Event: 18th ESACT Meeting 2003 - Animal Cell Technology Meets Genomics

    • Year: 2003 -  From gene to monoclonal antibody: efficient screening by cell sorting

      Autoren: Borth, N., Böhm, E., Grillari, J., Löscher, M., Gross, S., Voglauer, R., Ferko, B., Kunert, R., Katinger, H.

      Event: 18th ESACT Meeting 2003 - Animal Cell Technology Meets Genomics

    • Year: 2003 -  Immortalisierung von humanen Zellen mit Telomerase – Schlüssel zur Unsterblichkeit?

      Autoren: Voglauer, R., Grillari, J., Katinger, H.

      Event: Mancare 2003, Urologisch-Andrologisches Fachsymposium

    • Year: 2002 -  Establishment and characterization of a human fibroma cell line expressing hTERT

      Autoren: Voglauer, R., Grillari, J., Sterovsky, T., Klug, H., Wieser, M., Günsberg, P., Hemetsberger, T., Hieslmayer, S., Katinger, H., Pfragner R.

      Event: ISAC 2002 XXI Congress of the International Society for Analytical Cytology

    • Year: 2002 -  SNEV, a novel protein involved in replicative senescence and immortalization

      Autoren: Grillari, J., Voglauer, R., Fortschegger, K., Löscher, M., Chang, M., Grabherr, R.M., Sterovsky, T., Gross, S., Katinger, H.

      Event: French-Austrian Aging Workshop

    • Year: 2002 -  Confirmation of newly discovered protein-protein interactions, involving both: the splicing machinery and the ubiquitination system

      Autoren: Löscher, M., Wostry, M., Grillari, J., Katinger, H.

      Event: Biochemical Aspects of Health and Disease

    • Year: 2002 -  SNEV: A novel protein involved in ubiquitination and RNA metabolism

      Autoren: Löscher, M., Wostry, M., Katinger, H., Grillari, J.

      Event: 5th International workshop on Proteasomes

    • Year: 2002 -  The novel protein Blom7: expression in different expressionsystems and purification.

      Autoren: Zehentner,S., Grillari,J., Katinger,H.,

      Event: Joint annual meeting of the Österreichische Gesellschaft für Biotechnologie ÖGBM, ÖGGGT, ÖGBT and ANGT 2002

    • Year: 2002 -  Etablierung von humanen Tumorzelllinien durch Expression der katalytischen Untereinheit von humaner Telomerase.

      Autoren: Voglauer, R., Grillari, J., Sterovsky, T., Günsberg, P., Hieslmayer, S., Hemetsberger, T., Wieser, M., Katinger, H., Pfragner, R.

      Event: Workshop der österreichischen Gesellschaft für Zellkultur und der European Tissue Culture Society: Neues aus Zell- und Gewebekultur

    • Year: 2002 -  Determination of differences in protein profiles of young, quiescent and senescent human umbilical vein endothelial cells (HUVEC) by 2-dimensional gel electrophoresis

      Autoren: Chang, M., Marzban, G., Sterovsky,T., Hemetsberger, T., Grillari, J., Katinger, H.

      Event: 6th International Symposium on Neurobiology and Neuroendocrinology of Aging 2002

    • Year: 2002 -  Killer T cells: A promising new tool for adoptive immunotherapy

      Autoren: Jursik, C., Voglauer, R., Grillari, J., Hemetsberger, T., Jungfer, H., Katinger, H.

      Event: 5. International Conference on new trends in Immunosuppression

    • Year: 2002 -  Two-dimensional gel electrophoresis of human umbilical vein endothelial cells (HUVEC): differences in protein profiles of young, quiescent and senescent cells.

      Autoren: Chang, M., Marzban, G., Sterovsky, T., Hemetsberger, T., Grillari, J., Katinger, H.

      Event: 13th Wiener Symposium on Experimental Gerontology 2002

    • Year: 2002 -  Antibody secreting cell lines as model systems for affinity matrix secretion assay based cell sorting.

      Autoren: Böhm, E., Voglauer, R., Kunert, R., Grillari, J., Gross, S., Ferko, B., Katinger, H., Borth, N.

      Event: 15th Heidelberg Cytometry Symposium (HCS) Annual Meeting of the German Society of Cytometry (DGfZ)

    • Year: 2002 -  Complementation of a pso4/prp19 mutant strain of Saccharomyces cerevisiae by human SNEV

      Autoren: Grillari, J., Stadler, G., Katinger, H.

      Event: 1st International Conference on Ubiquitin, Ubiquitin-like Proteins, and Cancer 2002

    • Year: 2002 -  SNEV: A gene involved in pre mRNA processing and ubiquitin ligation is downregulated in senescent cells

      Autoren: Grillari, J., Fortschegger, K., Gross, S., Grabherr, R.M., Katinger, H.

      Event: First Conference on Functional Genomics of Aging

    • Year: 2002 -  SNEV, a protein involved in replicative senescence and immortalization.

      Autoren: Grillari, J., Voglauer, R., Fortschegger, K., Gross, S., Sterovsky, T., Grabherr, R.M., Löscher, M., Katinger, H.

      Event: Molekulare Biologie des Mammakarzinoms – vom Labor zur Klinik 2002

    • Year: 2002 -  SNEV: A gene involved in pre mRNA processing and ubiquitin ligation is downregulated in senescent cells

      Autoren: Grillari, J., Fortschegger, K., Gross, S., Voglauer, R., Sterovsky, T., Grabherr, R.M., Katinger, H.

      Event: Second EuroConference on Normal Ageing, Longevity, and Age-related diseases

    • Year: 2001 -  Cloning, Expression and Purification of Blom4, a subunit of the exocyst complex

      Autoren: Kaisermayer, C., Grillari, J., Gross, S., Katinger, H.

      Event: ÖGBT, ÖGGGT, ÖGMB Joint Meeting 2001

    • Year: 2001 -  Age-related alteration in the protein expression profile of C57BL/6J mice pituitaries using proteomic tools

      Autoren: Marzban, G., Flurkey, K., Grillari, J., Reisinger, E., Chang, M., Katinger, H.

      Event: Brain Aging, 2nd Neurobiology of Aging Conference

    • Year: 2001 -  SNEV: A novel nuclear matrix protein involved in replicative senescence

      Autoren: Grillari, J., ,Fortschegger, K., Voglauer, R., Gross, S., Sterovsky, T., Grabherr, R.M., Katinger, H.

      Event: Institut für Biomedizinische Alternsforschung, österr. Akademie der Wissenschaft

    • Year: 2000 -  Subtractive hybridization of mRNA from early passage and senescent endothelial cells

      Autoren: Grillari, J., Hohenwarter, O., Grabherr, R.M., Katinger, H.

      Event: Jahrestagung der Österreichischen Gesellschaft für Biotechnologie, ÖGBT-Jahrestagung 2000

    • Year: 2000 -  Screening for proteins interacting with a newly identified gene by using the yeast-two hybrid system

      Autoren: Löscher M., Grillari J., Katinger H.

      Event: Recombinant Protein Production with prokaryotic and eukaryotic cells 2000 - A comparative view on host physiology

    • Year: 2000 -  Substractive hybridization of mRNA from early passage and senescent endothelial cells

      Autoren: Grillari J., Hohenwarter O., Grabherr R.M., Katinger H.

      Event: Jahrestagung der Österreichischen Gesellschaft für Biotechnologie

    • Year: 2000 -  Recombinant expression and purification of a nuclear matrix protein

      Autoren: Gross, S., Grillari, J., Grabherr, R. M., Dockal, M., Katinger, H.

      Event: Recombinant Protein Production with prokaryotic and eukaryotic cells 2000 - A comparative view on host physiology

    • Year: 2000 -  Analysis of age-dependent protein expression in cultured human umbilical vein endothelial cells by two-dimensional electrophoresis

      Autoren: Marzban, G., Hemetsberger, T., Grillari, J., Hohenwarter, O., Katinger, H.

      Event: Biological Aging

    • Year: 1999 -  Isolation of differentially expressed genes from early passage and senescent endothelial cells

      Autoren: Grillari, J., Hohenwarter, O., Grabherr, R.M., Katinger, H.

      Event: International Conference on Experimental Gerontology 1999

    • Year: 1998 -  Subtractive Hybridization of mRNA from young and senescent endothelial cells

      Autoren: Grillari, J., Hohenwarter, O., Fortschegger, K., Grabherr, R. M., Katinger H.

      Event: Genetics of Aging

    • Year: 1998 -  Screening for differentially expressed mRNAs from young and senescent endothelial cells

      Autoren: Grillari, J. Hohenwarter, O. Marzban, G. Katinger, H.

      Event: 4th International symposium on Neurobiology and Neuroendocrinology of ageing 1998

    • Year: 1998 -  Screening for differentially expressed mRNAs from young and senescent endothelial cells

      Autoren: Grillari, J., Hohenwarter, O., Fortschegger, K., Grabherr, R. M., Katinger H.

      Event: Fourth International Symposium on Neurobiology and Neuroendocrinology of Aging

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