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Lukas Mach

Portrait Lukas Mach
classifications according to Statistics Austria

Research Focus

Biosynthesis and intracellular trafficking of secretory and lysosomal/vacuolar proteins, glycosylation and other post-translational protein modifications as determinants of protein structure and function, catalytic properties and physiological functions of proteases and glycosylation enzymes, proteolysis and its pathological and biotechnological relevance, recombinant expression of biotherapeutics in plants and insect cells.

free keywords glycobiology proteases cell biology

 

Career

  • 2018 Full Professor of Cell Biology, Department of Applied Genetics and Cell Biology, University of Natural Resources and Life Sciences, Vienna
  • 2010 - 2014 Head of Department of Applied Genetics and Cell Biology, University of Natural Resources and Life Sciences, Vienna
  • 2004 - 2018 Associate Professor at Institute of Applied Genetics and Cell Biology, University of Natural Resources and Life Sciences, Vienna
  • 1999 - 2004 Assistant Professor at Center of Applied Genetics, University of Natural Resources and Life Sciences, Vienna (BOKU)
  • 1995 - 1999 Assistant Professor ("Lecturer"), Dept. of Biochemistry, University of Western Australia, Nedlands, Australia
  • 1994 - 1995 Scientist, Division of Immunological Research, IMMUNO AG, Vienna
  • 1989 - 1994 Doctoral studies (McGill University, Montreal, Canada; University of Natural Resources and Life Sciences, Vienna)

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    Presentations

    List by country with the number of lectures given there:

    • Austria+' '+9
    • Finland+' '+1
    • Italy+' '+1
    • Slovenia+' '+5
    • Sweden+' '+1
    • Switzerland+' '+1
    • Thailand+' '+1
    • United States+' '+4

    23 lecures found.

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    • Year: 2022 - Factors defining the proteolytic susceptibility of monoclonal antibodies in the tobacco apoplast

      Art:   Talk - Keynote Speaker (Invited Speaker)

      Autoren: Mach, L

      Event: 5th Conference on Plant Proteases

      Period: 06.09.2022 - 08.09.2022  | Location: Ljubljana, Slovenia

    • Year: 2015 - Unable to express one of leptospiral genes of leucine-rich repeat protein in Lactobacillus plantarum

      Art:   Poster - Selected presentation

      Autoren: Suphatpahirapol, C; Nguyen, TH; Mach, L; Nitipane, S; Wajjwalku, W; Keawsompong, S; Haltrich, D; Prapong, S

      Event: Eigth Asian Conference for Lactic Acid Bacteria ACLAB 2015

      Period: 08.07.2015 - 10.07.2015  | Location: Bangkok, Thailand

    • Year: 2014 - Proteolysis of Anti-HIV Antibodies Manufactured in Nicotiana Benthamiana: Identification and Characterization of Antibody-Degrading Papain-Like Cysteine Proteinases

      Art:   Talk - Keynote Speaker (Invited Speaker)

      Autoren: Niemer, M; Mehofer, U; Verdianz, M; Porodko, A; Schähs, P; Kracher, D; van der Hoorn, R; Lenarcic, B; Novinec, M; Mach, L

      Event: 14th International Symposium on Proteinases, Inhibitors and Biological Control 2014

      Period: 06.09.2014 - 10.09.2014  | Location: Portoroz, Slovenia

    • Year: 2013 - The role of the mannose 6-phosphate/insulin-like growth factor II receptor and its ligands in cancer cell invasion

      Art:   Talk - Keynote Speaker (Invited Speaker)

      Autoren: Mach, L

      Event: Colloquia in Chemical Sciences, University of Ljubljana

      Period: 17.04.2013  | Location: Ljubljana, Slovenia

    • Year: 2012 - Degradation of recombinant proteins by plant cysteine proteinases

      Art:   Talk - Keynote Speaker (Invited Speaker)

      Autoren: Niemer, M; Mehofer, U; Verdianz, M; Schaller, A; van der Hoorn, R; Mach, L

      Event: FA0804 COST Action Molecular farming 2012 -Plants as a production platform for high value proteins

      Period: 16.02.2012 - 17.02.2012  | Location: Vienna, Austria

    • Year: 2012 - Human cathepsin O: glycosylation, processing and cellular activity

      Art:   Talk - Keynote Speaker (Invited Speaker)

      Autoren: Aufy, M; Porodko, A; Stadlmann, J; Gruber, C; Mach, L

      Event: 13th International Symposium on Proteinases, Inhibitors and Biological Control 2012

      Period: 22.09.2012 - 26.09.2012  | Location: Portoroz, Slovenia

    • Year: 2011 - Degradation of recombinant monoclonal antibodies by plant cysteine proteinases

      Art:   Talk - Selected presentation

      Autoren: Mach, L.

      Event: 1st International Plant Protease Conference 2011

      Period: 10.04.2011 - 14.04.2011  | Location: Hemavan, Sweden

    • Year: 2011 - The human lysosomal cysteine protease cathepsin O is N- and O-glycosylated

      Art:   Poster - Selected presentation

      Autoren: Aufy, M., Porodko, A., Stadlmann, J., Mach, L.

      Event: 21st International Symposium on Glycoconjugates GLYCO 21, 2011

      Period: 21.08.2011 - 26.08.2011  | Location: Vienna, Austria  | Organizer: The International Glycoconjugate Organisation | Organizer: Universität für Bodenkultur Wien, Universität Wien, BMWF

    • Year: 2011 - Biosynthesis, intracellular transport and subcellular localization of human cathepsin O

      Art:   Talk - Selected presentation

      Autoren: Aufy, M., Nimmerfall, E., Mach, L.

      Event: 28th Winter School on Proteinases and Their Inhibitors 2011

      Period: 23.02.2011 - 27.02.2011  | Location: Tiers, Italy

    • Year: 2011 - The role of the mannose 6-phosphate/IGF-II receptor and it's diverse ligands in cancer cell invasion

      Art:   Talk - Selected presentation

      Autoren: Mach, L.

      Event: ICA Symposium 2011

      Period: 01.07.2011 - 02.07.2011  | Location: Salzburg, Austria

    • Year: 2011 - The two N-glycans of murine Cellular Repressor of E1A-stimulated Genes (CREG) are both engaged in lysosomal sorting of the protein

      Art:   Poster - Selected presentation

      Autoren: Schähs, P., Schönbacher, A., Steinschauer, V., Porodko, A., Stadlmann, J., Mach, L.

      Event: 21st International Symposium on Glycoconjugates GLYCO 21, 2011

      Period: 21.08.2011 - 26.08.2011  | Location: Vienna, Austria  | Organizer: The International Glycoconjugate Organisation | Organizer: Universität für Bodenkultur Wien, Universität Wien, BMWF

    • Year: 2011 - Antonio Baici and the mysteries of tumour cathepsin B

      Art:   Talk - Selected presentation

      Autoren: Mach, L.

      Event: Symposium in the honour of Antonio Baici and Heinz Gehring, University of Zürich 2011

      Period: 15.04.2011  | Location: Zürich, Switzerland

    • Year: 2010 - Characterization of Drosophila melanogaster cellular repressor of E1A-stimulated genes (CREG)

      Art:   Poster - Selected presentation

      Autoren: Schähs, P., Mach, L.

      Event: 2nd ÖGMBT Annual Meeting 2010

      Period: 27.09.2010 - 29.09.2010  | Location: Vienna, Austria  | Organizer: ÖGMBT (Austrian Association of Molecular Life Sciences and Biotechnology)

    • Year: 2010 - Biosynthesis, intracellular transport and subcellular localization of human cathepsin O

      Art:   Talk - Selected presentation

      Autoren: Aufy, M., Nimmerfall, E., Mach, L.

      Event: 12th Symposium on Proteases, Inhibitors and Biological Control 2010

      Period: 25.09.2010 - 29.09.2010  | Location: Portoroz, Slovenia

    • Year: 2010 - Biosynthesis, intracellular transport and subcellular localization of human cathepsin O

      Art:   Poster - Selected presentation

      Autoren: M. Aufy, E. Nimmerfall, L.Mach

      Event: 2nd ÖGMBT Annual Meeting 2010

      Period: 27.09.2010 - 29.09.2010  | Location: Vienna, Austria  | Organizer: ÖGMBT (Austrian Association of Molecular Life Sciences and Biotechnology)

    • Year: 2009 - Consistent1,4-galactosylation of monoclonal antibodies produced in plants.

      Art:   Poster - Selected presentation

      Autoren: Castilho, A., Strasser, R., Stadlmann, J., Kunert, R., Gattinger, P., Altmann, F., Mach, L., Steinkellner, H

      Event: 15th European Carbohydrate Symposium 2009

      Period: 19.07.2009 - 24.07.2009  | Location: Vienna, Austria

    • Year: 2009 - Cloning, expression and purification of human recombinant lactoperoxidase

      Art:   Talk - Selected presentation

      Autoren: Stampler, J., Furtmüller, P.G., Soudi, M., Mach, L., Obinger, C.

      Event: 6th International Human Peroxidase Meeting 2009

      Period: 19.04.2009 - 22.04.2009  | Location: Chapel Hill, NC, USA

    • Year: 2009 - Characterization of the beta1,3-galactosyltransferase indispensable for the modification of Arabidopsis N-glycans with Lewis A epitopes.

      Art:   Talk - Selected presentation

      Autoren: Strasser, R., Vavra, U., Schoberer, J., Svoboda, B., Glössl, J., Leonard, R., Altmann, F., Steinkellner, H., Mach, L.

      Event: 15th European Carbohydrate Symposium 2009

      Period: 19.07.2009 - 24.07.2009  | Location: Vienna, Austria

    • Year: 2009 - Role of β-N-acetylhexosaminidases in the formation of paucimannosidic N-glycans in plants

      Art:   Talk - Selected presentation

      Autoren: Glössl, J., Liebminger, E., Schoberer, J., Svoboda, B., Altmann, F., Steinkellner, H., Mach, L., Strasser, R.

      Event: GLYCOBIOLOGY 2009

      Period: 12.11.2009 - 15.11.2009  | Location: San Diego, CA, USA

    • Year: 2009 - Role of Arabidopsis β-N-acetylhexosaminidases in the formation of paucimannosidic N-glycans.

      Art:   Poster - Selected presentation

      Autoren: Liebminger, E., Schoberer, J., Svoboda, B., Glössl, J., Altmann, F., Steinkellner, H., Mach, L., Strasser, R.

      Event: 15th European Carbohydrate Symposium 2009

      Period: 19.07.2009 - 24.07.2009  | Location: Vienna, Austria

    • Year: 2009 - Glyco-engineering in plants: production of monoclonal antibodies containing homogeneously β1,4-galactosylated human-type N-glycans.

      Art:   Talk - Selected presentation

      Autoren: Glössl, J., Strasser, R., Castilho, A., Kunert, R., Altmann, F., Mach, L., Steinkellner, H.

      Event: GLYCOBIOLOGY 2009

      Period: 12.11.2009 - 15.11.2009  | Location: San Diego, CA, USA

    • Year: 2008 - Characterization of the beta1,3-galactosyltransferase indispensable for the modification of plant N-glycans with Lewis a epitopes

      Art:   Poster - Selected presentation

      Autoren: Strasser, R., Vavra, U., Schoberer, J., Svoboda, B., Glössl, J., Léonard, R., Stadlmann, J., Altmann, F., Steinkellner, H., Mach, L.

      Event: 6th International Conference on Glycosyltransferases GlycoT 2008

      Period: 17.05.2008 - 20.05.2008  | Location: Atlanta, GA, USA

    • Year: 2008 - Role of Arabidopsis beta-N-acetylhexosaminidases in the formation of paucimannosidic N-glycans

      Art:   Poster - Selected presentation

      Autoren: Liebminger, E., Schoberer, J., Svoboda, B., Glössl, J., Altmann, F., Steinkellner, H., Mach, L., Strasser, R.

      Event: 26th Congress of the Federation of European Societies of Plant Biology FESPB 2008 tohether with 11th annual international meeting for experimental moss research and 8th International Peroxidase Symposium, Peroxidase 2008

      Period: 17.08.2008 - 22.08.2008  | Location: Tampere, Finland

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