Michael Traxlmayr
Priv.-Doz. Dipl.-Ing.Dr. Michael Traxlmayr
Institute of Biochemistry
Location Muthgasse 18, 1190 Wien
Email michael.traxlmayr@boku.ac.at
Tel: +43 1 47654-77274
ORCID: 0000-0002-2108-582X, opens in new window.
AuthorId : 55008094000, opens in new window.
Research Focus
CAR T cells, Cancer immunotherapy, Protein engineering, Biochemistry
Career
- 2022 Habilitation
- 2017 Senior Scientist (BOKU)
- 2016 - 2017 Postdoc (BOKU)
- 2013 - 2015 Postdoc (Massachusetts Institute of Technology, MIT)
- 2008 - 2012 Dissertation (BOKU)
- 2002 - 2008 Master Food- and Biotechnology (BOKU)
Awards
- Year: 2020 Awards: BOKU invention of the year
- Year: 2013 Awards: BOKU Talent Award
- Year: 2013 Awards: Schrödinger fellowship for postdoctoral research at MIT
- Year: 2013 Awards: ÖGMBT doctoral thesis award (Austrian Association of Molecular Life Sciences and Biotechnology)
Projects
0 Projects found.
Publications
Knowledge Transfer to Society
Media
Presentations
List by country with the number of lectures given there:
- Österreich+' '+13
- Kanada+' '+1
- Deutschland+' '+1
- Niederlande+' '+1
- Portugal+' '+3
- Spanien+' '+1
- Vereinigtes Königreich+' '+2
- Vereinigte Staaten+' '+4
26 lecures found.
Year: 2024 - Engineering of molecular ON- and OFF-switches for controlling CAR T cells
Art: Vortrag - Ausgewählte Präsentation
Autoren: Zajc, CU; Sumesgutner, D; Mayer, J; Sylvander, E; Teufl, M; Traxlmayr, MW
Event: EBMT-EHA 6th European CAR T-cell Meeting
Year: 2023 - Engineering molecular switches for functional control of CAR T cells with an orally available small molecule drug.
Art: Poster - Ausgewählte Präsentation
Autoren: Zajc, CU; Dobersberger, M; Schaffner, I; Mlynek, G; Pühringer, D; Salzer, B; Djinović-Carugo, K; Obinger, C; Lehner, M; Traxlmayr, MW
Event: EHA-EBMT 5th European CAR T-cell Meeting
Period: 09.02.2023 - 11.02.2023 | Location: Rotterdam
Year: 2023 - Novel protein engineering strategies for next-generation CAR T-cells.
Art: Vortrag - Keynote Speaker (eingeladener Vortrag)
Autoren: Traxlmayr, MW
Event: Janssen R&D Symposium on Next-Generation Cell Therapy
Period: 22.06.2023 | Location: Beerse
Year: 2023 - Unraveling the FMC63-CD19 affinity
Art: Poster - Ausgewählte Präsentation
Autoren: Seigner, J; Zajc, CU; Dötsch, S; Eigner, C; Laurent, E; Busch, DH; Lehner, M; Traxlmayr, MW
Event: Keystone meeting on Emerging Cellular Therapies at the Forefront of Cancer Immunotherapy
Period: 29.01.2023 - 02.02.2023 | Location: Banff
Year: 2023 - Incorporating drug regulated switch modules to improve the safety of cellular therapies.
Art: Vortrag - Keynote Speaker (eingeladener Vortrag)
Autoren: Traxlmayr, MW
Event: Gamma Delta T Therapies Summit, Boston
Period: 25.07.2023 - 27.07.2023 | Location: Boston
Year: 2023 - Novel protein engineering concepts to improve the safety and specificity of CAR T cells
Art: Vortrag - Keynote Speaker (eingeladener Vortrag)
Autoren: Traxlmayr, MW
Event: PEGS Boston
Period: 15.05.2023 - 19.05.2023 | Location: Online | Location: Boston, MA, USA | Location: Boston | Location: Boston, Massachussets | Location: Online | Location: Boston, MA, USA
Year: 2023 - Taking control of CAR T cells- Engineering of molecular ON-switches for cellular therapies
Art: Vortrag - Ausgewählte Präsentation
Autoren: Charlotte U. Zajc, Markus Dobersberger, Manfred Lehner and Michael W. Traxlmayr
Event: ÖGMBT Annual Meeting
Year: 2023 - Novel Concepts to Regulate CAR T Cell Activity with Small Molecule Drugs in Vivo
Art: Vortrag - Keynote Speaker (eingeladener Vortrag)
Autoren: Traxlmayr, MW
Event: PEGS Europe
Period: 14.11.2023 - 16.11.2023 | Location: Lisbon | Location: Lisbon, PORTUGAL
Year: 2022 - Entwicklung von stabilisierten CD19-Varianten für die Detektion und Affinitätsanalyse von CAR-T Zellen
Art: Vortrag - Keynote Speaker (eingeladener Vortrag)
Autoren: Michael W. Traxlmayr
Event: CAR-T Cell Network Meeting
Period: 14.03.2022 | Location: Vienna, Austria
Year: 2022 - PhosphoFlowSeq – a novel high-throughput kinase activity assay for the identification of drug resistance mutations in EGFR
Art: Poster - Ausgewählte Präsentation
Autoren: Teufl, M; Wagner, A; Gold, L; Lehner, M; Obinger, C; Sykacek, P; Traxlmayr, M
Event: PEGS Europe 2022
Period: 14.11.2022 - 16.11.2022 | Location: Barcelona, Spain
Year: 2022 - Reversible control of CAR-T therapy to reduce toxicity and improve clinical outcomes
Art: Vortrag - Keynote Speaker (eingeladener Vortrag)
Autoren: Michael W. Traxlmayr
Event: Onco Cell Therapy Summit Europe
Period: 02.11.2022 - 03.11.2022 | Location: Amsterdam, Netherlands
Year: 2020 - Detailed analysis of lipocalin-based molecular ON-switches in biochemical assays and in CAR T cells
Art: Vortrag - Ausgewählte Präsentation
Autoren: Brey, CU; Dobersberger, M; Schaffner, I; Salzer, B; Steinberger, P; De Sousa Linhares, A; Lehner, M; Traxlmayr, MW
Event: Keystone Symposia meeting on Emerging Cellular Therapies: Cancer and Beyond
Period: 08.02.2020 - 12.02.2020 | Location: Banff, AB, Canada
Year: 2019 - AVIDCARS - A NOVEL PLATFORM FOR INTEGRATION OF MULTIPLE INPUT SIGNALS BY ONE CAR MOLECULE
Art: Vortrag - Ausgewählte Präsentation
Autoren: Salzer, B; Brey, CU; Schueller, C; Schoeber, M; Lobner, E; Dushek, O; Holter, W; Traxlmayr, MW; Lehner, M
Event: International Conference on Lymphocyte Engineering (ICLE)
Period: 13.09.2019 - 15.09.2019 | Location: London, UK
Year: 2019 - Construction of a molecular ON-switch for controlling CAR T cells with an orally available small molecule
Art: Vortrag - Ausgewählte Präsentation
Autoren: Brey, CU; Dobersberger, M; Schaffner, I; Mlynek, G; Pühringer, D; Salzer, B; Djinović-Carugo. K; Obinger, C; Holter, W; Lehner, M; Traxlmayr, MW
Event: PEGS Boston
Period: 08.04.2019 - 12.04.2019 | Location: Boston, MA, USA
Year: 2019 - A LIPOCALIN-BASED ON-SWITCH FOR CONTROLLING CAR T CELLS WITH AN ORALLY AVAILABLE DRUG
Art: Vortrag - Ausgewählte Präsentation
Autoren: Brey, C; Dobersberger, M; Schaffner, I; Mlynek, G; P?hringer, D; Salzer, B; Djinovic-Carugo, K; Obinger, C; Holter, W; Traxlmayr, M; Lehner, M
Event: International Conference on Lymphocyte Engineering (ICLE)
Period: 13.09.2019 - 15.09.2019 | Location: London, UK
Year: 2019 - Moderne Krebsforschung – Neue Chancen durch personalisierte Medizin?
Art: Vortrag - Keynote Speaker (eingeladener Vortrag)
Autoren: Heffeter, P; Jäger, U; Traxlmayr, M
Event: Science Talk
Period: 23.09.2019 | Location: Vienna, Austria | Location: Vienna, Austria
Year: 2016 - Structures and thermodynamics of Fcab-antigen complexes.
Art: Poster - Ausgewählte Präsentation
Autoren: Lobner, E., Humm, A.-S., Göritzer, K., Mlynek, G., Hasenhindl, C., Traxlmayr, M., Djinoviv-Carugo, K., Obinger, C.
Event: PEGS 2016
Period: 25.04.2016 - 29.04.2016 | Location: Boston, MA, USA
Year: 2016 - A hyperstable miniprotein as an alternative to antibodies
Art: Vortrag - Ausgewählte Präsentation
Autoren: Traxlmayr, MW; Kiefer, JD; Srinivas, RR; Lobner, E; Tisdale, AW; Mehta, NK; Tidor, B; Wittrup KD
Event: 8th ÖGMBT Annual Meeting 2016
Period: 12.09.2016 - 14.09.2016 | Location: Graz, Austria
Year: 2014 - Stability assessment on a library scale – A rapid method for the evaluation of the commutability and insertion of residues in C-terminal loops of the CH3 domains of IgG1-Fc.
Art: Vortrag - Ausgewählte Präsentation
Autoren: Hasenhindl, C., Traxlmayr, M.W., Wozniak-Knopp, G ., Jones, P.C., Stadlmayr, G., Rüker, F., Obinger, C.
Event: Human Antibodies and Hybridomas Conference 2014
Period: 31.03.2014 - 02.04.2014 | Location: Vienna, Austria
Year: 2012 - Systematic analysis of the C-terminal loops of IgG1-Fc for their usability in Modular Antibody Engineering
Art: Poster - Ausgewählte Präsentation
Autoren: Hasenhindl, C., Wozniak-Knopp1, G., Traxlmayr, M.W., Hackl, M., Stadlmayr, G., Rüker F. and Obinger C.
Event: 9th International Conference on Protein Stability 2012 - From molecular level to market applications
Period: 02.05.2012 - 04.05.2012 | Location: Lisbon, Portugal
Year: 2012 - Measures to Enhance Half-Life and Stability (Preconference Short Course)
Art: Vortrag - Keynote Speaker (eingeladener Vortrag)
Autoren: Rüker, F; Traxlmayr, M;
Event: Protein and Antibody Engineering Summit PEGS Europe 2012
Period: 06.11.2012 - 08.11.2012 | Location: Vienna, Austria
Year: 2012 - Stability engineering of human IgG1-Fc to resist boiling
Art: Poster - Ausgewählte Präsentation
Autoren: Stadlmayr, G., Schaffner, I., Traxlmayr, M., Wozniak-Knopp, G., Hasenhindl, C., Rüker, F. and Obinger, C.
Event: 9th International Conference on Protein Stability 2012 - From molecular level to market applications
Period: 02.05.2012 - 04.05.2012 | Location: Lisbon, Portugal
Year: 2012 - Stability engineering of IgG1-Fc and construction of a “protein stability landscape” by high throughput sequencing
Art: Vortrag - Ausgewählte Präsentation
Autoren: Traxlmayr, M.W.Faissner, M., Hasenhindl, C., Hackl, M., Stadlmayr, G., Rüker, F. and Obinger, C.
Event: 9th International Conference on Protein Stability 2012 - From molecular level to market applications
Period: 02.05.2012 - 04.05.2012 | Location: Lisbon, Portugal
Year: 2011 - Stability engineering of human IgG1-Fc and application in modular antibody engineering
Art: Poster - Ausgewählte Präsentation
Autoren: Hasenhindl,C., Traxlmayr, M. W., Faissner, M., Stadlmayr, G., Rüker, F., Obinger, C.
Event: 3rd PEGS Europe Protein & Antibody Engineering Summit 2011
Period: 11.10.2011 - 13.10.2011 | Location: Hanover, Germany
Year: 2011 - Stability-engineering of human IgG1-Fc by using yeast display
Art: Poster - Ausgewählte Präsentation
Autoren: Traxlmayr, M. W., Faissner, M., Stadlmayr, G., Rüker, F., Obinger, C.
Event: PEGS - Protein and Antibody Engineering Summit 2011
Period: 09.05.2011 - 12.05.2011 | Location: Boston, MA, USA
Year: 2009 - Engineered human IgG1-Fc binding to integrin
Art: Poster - Ausgewählte Präsentation
Autoren: Traxlmayr, M., Wozniak-Knopp, G., Rüker, F., Obinger, C.
Event: 20th IBC's Annual International Conference on Antibody Engineering 2009
Period: 06.12.2009 - 10.12.2009 | Location: San Diego, CA, USA