Renate Kunert
Univ.Prof. Dipl.-Ing. Dr.nat.techn. Renate Kunert
Institute of Animal Cell Technology und Systems Biology
Location Muthgasse 11, 1190 Wien
Email renate.kunert@boku.ac.at
Tel: +43 1 47654-79852
ORCID: 0000-0002-3397-3621
6603682350: AuthorId
B-9185-2018: ResearcherId
Research Focus
medical biotechnology, immunoglobulins, hormones, surface proteins, complement system, recombinant protein expression in animal cells, bioprocesses, protein chemistry
Career
- 2009 professor for animal cell factory design
- 2002 Venia dozendi in the fields of biopharmaceutical technology
- 1994 doctoral theses: Sequenzing and systematic charakterization of genes of human antibobies against HIV
- 1989 diploma theses: Sialo- und asialoglycoconjugates as immunogenes: preparation, charakterisation and i
Projects
0 Projects found.
Publications
Knowledge Transfer to Society
Media
Presentations
Year: 2023 - C1q-IgM interaction studies with recombinant globular C1q variants
Autoren: John, M.; Hunjadi, M.; Hawlin, V.; Kunert, R.
Event: 29th International Complement Workshop
Year: 2023 - Production of artificial globular C1q variants and performance of interaction studies with pentameric and hexameric IgM
Autoren: John, M.; Hunjadi, M.; Hawlin, V.; Kunert, R.
Event: 4th ESACT Frontiers Retreat
Year: 2022 - Functional Trimeric SARS-CoV-2 Envelope Protein Expressed in Stable CHO Cells
Autoren: Hunjadi, M; Mayrhofer, P; Abdur, R; Kunert, R
Event: 27th European Society for Animal Cell Technology ESACT Meeting 2022
Year: 2022 - Artificial C1q globular regions for C1q-IgM interaction studies
Autoren: John, M; Hunjadi, M; Billerhart, M; Sulaj, E; Hawlin, V; Kunert, R
Event: 27th European Society for Animal Cell Technology ESACT Meeting 2022
Year: 2019 - EVALUATION OF C1q BINDING AND COMPLEMENT ACTIVATION OF NEW RECOMBINANT HUMAN IGMS AS QUALITY PRODUCTION ATTRIBUTES
Autoren: Reiser, JB; Hennicke, J; Bally, I; Chouquet, A; Ling, WL; Reinhart, D; Altmann, F; Kunert, R; Thielens, N
Event: 17th European Meeting on Supercritical Fluids EMSF and 7th European Meeting on High Pressure Technology 2019
Year: 2019 - HIV-1 Envelope Glycoproteins as Immunogens - Expression and Manufacture
Autoren: Mundsperger, P; Kunert, R;
Event: ESACT meeting
Year: 2019 - Evaluation of C1p binding and complement activation of new recombinant human IgMs as quality attributes.
Autoren: J.-B. Reiser, J. Hennicke, I. Bally, A. Chouquet, W.-L. Ling, F. Altmann, R. Kunrt, N. Thielens
Event: 17th European Meeting on Supercritical Fluids EMSF and 7th European Meeting on High Pressure Technology 2019
Year: 2019 - Gene expression changes in response to expressed mAb variant in CHO cells
Autoren: Schwaigerlehner, L; Akhtar, S; Scholey, R; Torres, M; Mayrhofer, P; Dickson, AJ; Kunert, R
Event: 14th Asian Congress on Biotechnology ACB 2019
Year: 2019 - DoE-supported media formulations in high density perfusion processes
Autoren: Kunert, R; Castan, A; Mayrhofer, P
Event: 2nd Global Bioprocessing, Bioanalytics & ATMP Manufacturing Congress
Year: 2019 - Influence of Somatic Mutations on mAb Expression and Thermal Stability Properties
Autoren: Kunert, R; Schwaigerlehner, L; Mayrhofer, P;
Event: PEGS Europe 2019
Year: 2019 - DoE-supported perfusion medium development for maximum cell densities and optimized media consumption
Autoren: Mayrhofer, P; Damjanovic, L; Castan, A; Kunert, R
Event: 257th National Spring Meeting of the American Chemical Society ACS 2019
Year: 2019 - Process intensification through cell culture perfusion
Autoren: Patrick Mayrhofer, Renate Kunert
Event: 26th ESACT Meeting 2019
Year: 2019 - Does CHO gene expression change in response to expressed mAb variant?
Autoren: Schwaigerlehner, L; Kunert, R; Mayrhofer, P;
Event: 26th ESACT Meeting 2019
Year: 2019 - Pre-testing of media-composition for high density culture perfusion processes
Autoren: Kunert, Mayrhofer
Event: 2nd Global Bioprocessing, Bioanalytics & ATMP Manufacturing Congress
Year: 2019 - Historical background and story about first HIV mAs developed at Polymun/IAM
Autoren: Renate Kunert
Event: Education and Training in EAVI - A European HIV vaccine Programme
Year: 2018 - Does the degree of antibody maturation influence expression rate and stability of mAbs?
Autoren: Kunert, R; Schwaigerlehner, L; Mayrhofer, P
Event: HUMAN ANTIBODIES & HYBRIDOMAS 2018
Year: 2018 - Transcriptome analysis of a recombinant antibody-producing CHO cell line cultivated in feed-spiked medium
Autoren: Renate Kunert, David Reinhart, Lukas Damjanovic, Andreas Castan, Wolfgang Ernst
Event: Bioprocessing Summit Europe 2018
Year: 2018 - Making the strange more familiar: Influence of germinality content on mAb expression potentials and thermal stability properties
Autoren: Schwaigerlehner, L; Mayrhofer, P; Kunert, R
Event: 18th European Congress On Biotechnology 2018
Year: 2018 - Does mAb germinality correlate with productivity and biophysical protein properties?
Autoren: Schwaigerlehner, L; Mayrhofer, P; Kunert, R
Event: Antibody Engineering & Therapeutics 2018
Year: 2018 - Are somatic mutations of mAbs responsible for low expression and thermal stability?
Autoren: Schwaigerlehner, L; Mayrhofer, P; Kunert, R
Event: 10th ÖGMBT Annual Meeting & Biophysics Austria Annual Meeting 2018
Year: 2018 - CHO cell perfusion culture development beyond 200 × 10E6 cells/mL
Autoren: Mayrhofer, P; Wiederstein, F; Damjanovic, L; Castan, A; Kunert, R
Event: BioProcess International European Summit 2018
Year: 2018 - Humanization of a mouse antibody and subsequent analysis of expected immunogenicity by molecular dynamics simulations and in-silico T-cell epitope predictions.
Autoren: Mayrhofer, P; Schwaigerlehner, L; Oostenbrink, C; Kunert, R
Event: Antibody Engineering & Therapeutics 2018
Year: 2017 - Rational antibody humanization assisted by molecular dynamics simulations
Autoren: Schwaigerlehner, L; Pechlaner, M; Mayrhofer, P; Oostenbrink, C; Kunert, R
Event: 25th ESACT Meeting 2017
Year: 2017 - Complex polymeric IgM produced in Chinese hamster ovary (CHO) cells
Autoren: Hennicke, J; Reinhart, D; Kunert R
Event: 9th International Conference on Recombinant Protein Production RPP9 2017
Year: 2017 - Rational antibody humanization assisted by molecular dynamics simulations
Autoren: Schwaigerlehner, L; Mayrhofer, P; Pechlaner, M; Oostenbrink, C; Kunert, R
Event: 9th International Conference on Recombinant Protein Production RPP9 2017
Year: 2017 - IgM/IgA up- and down-stream topics
Autoren: Kunert, R
Event: IgM Tagung
Year: 2017 - Transcriptome analysis in high-producing CHO cell cultures: strategies to design high-performing cell culture media
Autoren: Reinhart, D; Castan, C; Damjanovic, L; Ernst, W; Kunert, R
Event: European Society for Animal Cell Technology 2017
Year: 2017 - Analyses of product quality of complex polymeric IgM produced by CHO cells
Autoren: Hennicke, J; Reinhart, D; Kunert R
Event: 25th ESACT Meeting 2017
Year: 2017 - Decision Finding For Production Systems And Expectations For The CHO System
Autoren: Kunert, R; Reinhart, D; Schwaigerlehner, L; Mundsperger, P; Hennicke, J; Sommeregger, W; Mayrhofer, P
Event: BioBrocess Cuba 2017
Year: 2017 - Development of DoE based fed-batch strategies for high-producing CHO cell cultures
Autoren: Reinhart, D; Castan, A; Damjanovic, L; Holub, B; Kunert, R
Event: European Society for Animal Cell Technology 2017
Year: 2017 - Antibody humanization strategies complemented with deimmunization for safe biotherapeutics
Autoren: Mayrhofer, P; Schwaigerlehner, L; Hoffmann-Freimüller, C; Geyeregger, R; Kunert, R
Event: BioBrocess Cuba 2017
Year: 2017 - Synthesis and vaccine potential of novel oligomannosides against HIV-1
Autoren: Trattnig, N; Pantophlet, R; Mayrhofer, P; Kunert, R, Kosma, P.
Event: VII EFMC International Symposium on Advances in Synthetic and Medicinal Chemistry
Year: 2017 - Synthesis and vaccine potential of novel oligomannosides against HIV-1
Autoren: Trattnig, N; Pantophlet, R; Mayrhofer, P; Kunert, R; Kosma, P.
Event: 19th European Carbohydrate Symposium 2017
Year: 2017 - Synthesis and vaccine potential of novel oligomannosides against HIV-1
Autoren: Trattnig, N; Pantophlet, R; Mayrhofer, P; Kunert, R; Kosma, P.
Event: 14th Bratislava Symposium on Saccharides BSS 2017
Year: 2017 - Rational antibody humanization assisted by molecular dynamics simulations
Autoren: Schwaigerlehner, L; Mayrhofer, P; Pechlaner, M; Oostenbrink, C; Kunert, R
Event: 25th ESACT Meeting 2017
Year: 2017 - Production of recombinant glycosylated polymeric IgM antibodies in CHO cells
Autoren: Hennicke, J; Grünwald-Gruber, C; Reinhart, D; Altmann, F; Kunert, R
Event: GlycoBioTec 2017
Year: 2016 - AllergoOncology: generation of a canine anti-EGFR anticancer IgE
Autoren: Fazekas, J; Singer, J; Matz, M; Mader, A; Spillner, E; Kunert, R; Jensen-Jarolim, E
Event: Meeting of the European Academy of Allergy and Clinical Immunology 2016
Year: 2016 - Investigation of different mAb expression potentials by use of complementary culture methods
Autoren: Schwaigerlehner, L; Mayrhofer, P; Kunert, R
Event: PEGS Europe 2016
Year: 2016 - Biphasic cultivation strategy to avoid Epo-Fc aggregation and optimize protein expression
Autoren: Reinhart, D; Kaisermayer, C; Gili, Andreas; Chang, Martina; Aberg, PM; Castan, A; Kunert, R
Event: BioProcess International Conference & Exhibition 2016
Year: 2016 - Purification of an aggregation prone protein: challenges and solutions for polymeric IgM production
Autoren: Hennicke, J; Lastin, AM; Reinhart, D; Kunert, R
Event: PEGS Europe 2016
Year: 2016 - Synthesis of bacterial mimetics of HIV-1 gp120 glycans
Autoren: Trattnig, N; Pantophlet, R; Mayrhofer, P; Kunert, R; Kosma, P.
Event: 28th International Carbohydrate Symposium 2016
Year: 2015 - Influence of cell culture media and feed supplements on cell metabolism and quality of IgG produced in CHO K1, CHO-S, and CHO DG44
Autoren: Reinhart, D; Kaisermayer, C; Damjanovic, L; Sommeregger, W; Gili, A; Schafellner, S; Castan, A; Kunert, R
Event: European Society for Animal Cell Technology
Year: 2015 - Follow the protein: the secretory pathway of recombinant proteins in Pichia pastoris tracked via live cell microscopy
Autoren: Puxbaum V., Landes N., Maccani A., Kunert R., Gasser B., Mattanovich D.
Event: 6th International Conference on Analysis of Microbial Cells at the Single Cell Level 2015
Year: 2015 - Tracking secretion of recombinant proteins in Pichia pastoris using live cell microscopy
Autoren: Puxbaum V., Landes N., Maccani A., Kunert R., Gasser B., Mattanovich D.
Event: EMBO/EMBL Symposium Seeing is Believing - Imaging the Processes of Life
Year: 2015 - Identification of expression bottlenecks of recombinant polymeric antibody production
Autoren: Reinhart, D; Sommeregger, W; Debreczeny, M; Gludovacz, E; Kunert, R
Event: European Society for Animal Cell Technology
Year: 2015 - Follow the protein: the secretory pathway of recombinant proteins in Pichia pastoris tracked via live cell microscopy
Autoren: Puxbaum V., Landes N., Maccani A., Kunert R., Gasser B., Mattanovich D.
Event: 6th International Conference on Analysis of Microbial Cells at the Single Cell Level 2015
Year: 2015 - Identification of bottlenecks in antibody expression using targeted gene integration
Autoren: Mayrhofer, P; Mader, A; Kratzer, B; Reinhart, D; Steinfellner, W; Sommeregger, W; Kunert, R
Event: 24th ESACT 2015 - Cells, Culture, Patients, Products
Year: 2014 - Cross-species comparison of recombinant protein secretion in CHO cells and Pichia pastoris
Autoren: Landes, Nils; Maccani, Andreas; Leitner, Christian; Maurer, Michael; Graf, Alexandra; Valli, Minoska; Gruber, Clemens; Modarres, Gerda; Altmann, Friedrich; Gasser, Brigitte; Ernst, Wolfgang; Kunert, Renate; Mattanovich, Diethard
Event: ECB16 2014
Year: 2014 - "Model based engineering of Pichia pastoris central metabolism enhances recombinant protein production"
Autoren: Hoppe, Frederik; Schillinger, Harald; Schrafvogl, Rudolf; Hutter, Melanie; Kunert, Renate; Eyer, Kurt; Maurer, Michael
Event: 5th International Conference on Biomolecular Engineering (ICBE)
Year: 2014 - Versatile RMCE Integration of Different Antibody Variants into Predictable Reference Sites in CHO Cells
Autoren: Mayrhofer, P; Mader, A; Kunert, R
Event: PEGS - Protein and Antibody Engineering Summit 2014
Year: 2014 - Advanced clarification of cell culture supernatant by 3M™ Emphaze™ AEX Hybrid Purifier for fast and economic bioprocessing of recombinant proteins
Autoren: Hoppe, Frederik; Schillinger, Harald; Schrafvogl, Rudolf; Hutter, Melanie; Kunert, Renate; Eyer, Kurt and Maurer, Michael
Event: ECB16 2014
Year: 2014 - RMCE reference sites – A valuable tool for comparing antibody expression capabilities in CHO cells
Autoren: Mayrhofer, P; Mader, A; Kunert, R
Event: 16th European Congress on Biotechnology 2014
Year: 2014 - Can225IgG, the first 'caninised' antibody against EGFR is highly effective in mediating tumor cell growth inhibition and phagocytosis in vitro
Autoren: Fazekas, J; Singer, J; Wang, W; Weichselbaumer, M; Matz, M; Mader, A; Steinfellner, W; Meitz, S; Mechtcheriakova, D; Sobanov, Y; Willmann, M; Stockner, T; Spillner, E; Kunert, R; Jensen-Jarolim, E
Event: European-Academy-of-Allergy-and-Clinical-Immunology Congress 2014
Year: 2014 - Rosa26 Bacterial Artificial Chromosomes as expression vehicles: A fast and effective way to generate stable high producing CHO cells
Autoren: Sommeregger, W; Gili, A; Zboray, K; Sterovsky, T; Casanova, E; Kunert, R
Event: 10th Protein and Antibody Engineering Summit
Year: 2014 - Cross-species comparison of recombinant protein secretion in CHO cells and Pichia pastoris
Autoren: Landes, Nils; Maccani, Andreas; Leitner, Christian; Maurer, Michael; Gasser, Brigitte; Ernst, Wolfgang; Kunert, Renate; Mattanovich, Diethard
Event: CHOgenome Workshop 2014
Year: 2013 - Characterization of model recombinant monoclonal IgM antibodies produced in CHO-DG44 cell lines
Autoren: Chromikova, V; Mader, A; Phan, T; Steinfellner, W; Landucci, G; Forthal, D; Kunert, R
Event: 7th Conference on Recombinant Protein Production RPP7 2013
Year: 2013 - Optimization of Recombinant Protein Expression in Chinese Hamster Ovary Cells
Autoren: Sommeregger, W.; Gili, A; Sterovsky, T; Casanova, E.; Kunert, R;
Event: 7th Conference on Recombinant Protein Production RPP7 2013
Year: 2013 - IgG to IgM class switch: Modification of protein properties by antibody engineering
Autoren: Mader, A; Chromikova, V; Kunert, R
Event: 2nd Workshop: The new ParadIgM - IgM from bench to clinic
Year: 2013 - Passive anti-EGFR immunotherapy in canine cancer patients - a comparative medicine study
Autoren: Fazekas, J; Singer, J; Wang, W; Weichselbaumer, M; Matz, M; Mader, A; Steinfellner, W; Meitz, S; Mechtcheriakova, D; Sobanov, Y; Stockner, T; Spillner, E; Kunert, R; Jensen-Jarolim, E
Event: World Allergy and Asthma Congress of the European-Academy-of-Allergy-and-Clinical-Immunology and World-Allergy-Organization
Year: 2013 - Expression of recombinant IgA antibodies and in-depth cell line characterization
Autoren: Reinhart, D; Sommeregger, W; Debreczeny, M; Gludovacz, E; Kunert, R
Event: European Society for Animal Cell Technology 2013
Year: 2013 - Transcriptome study of high and low producing recombinant Chinese hamster ovary cell lines
Autoren: Maccani, A., Tatto, N., Graf, A., Leitner, C., Mattanovich, D., Kunert, R., Ernst, W.
Event: 7th Conference on Recombinant Protein Production RPP7 2013
Year: 2013 - Powerful expression in Chinese Hamster Ovary cells using bacterial artificial chromosomes: parameters influencing productivity
Autoren: Sommeregger, W; Gili, A; Sterovsky, T; Casanova, E; Kunert, R
Event: 23rd ESACT Meeting - Better Cells for Better Health
Year: 2013 - Cross-species comparison of recombinant protein secretion in CHO cells and Pichia pastoris
Autoren: Landes, N; Maccani, A; Leitner, C; Maurer, M; Gasser, B; Ernst, W; Kunert, R; Mattanovich, D.
Event: 7th Conference on Recombinant Protein Production RPP7 2013
Year: 2012 - Human recombinant IgMs: a challenging molecule in mammalian cell expression
Autoren: Mader, A; Kunert, R
Event: 15th European Congress on Biotechnology ECB15 2012 - Biocrossroads
Year: 2012 - Recombinant IgAs Expressed In CHO Cells: Bottlenecks of Recombinant Cell Lines and Improved Production Strategies
Autoren: Renate Kunert
Event: Protein and Antibody Engineering Summit PEGS Europe 2012
Year: 2012 - Characterization of Recombinant IgA Producing CHO Cells
Autoren: Sommeregger, W; Reinhart, D; Kunert, R
Event: 4th ÖGMBT Annual Meeting 2012
Year: 2012 - Recombinant IgMs expressed in mammalian cells
Autoren: Renate Kunert
Event: FA0804 COST Action Molecular farming 2012 -Plants as a production platform for high value proteins
Year: 2012 - Production of recombinant IgMs in mammalian cells
Autoren: Chromikova, V; Mader, A; Steinfellner, W; Kunert, R
Event: 4th ÖGMBT Annual Meeting 2012
Year: 2012 - Comparison of IgM production in different mammalian cell lines
Autoren: Chromikova, V; Mader, A; Steinfellner, W; Kunert, R
Event: 15th European Congress on Biotechnology ECB15 2012 - Biocrossroads
Year: 2011 - Serum-free production and purification of two anti-HIV-1 human IgAs
Autoren: Reinhart, D; Weik, R; Kunert, R
Event: 3rd ÖGMBT Annual Meeting 2011
Year: 2011 - Screening and quantification of human IgMs using BioLayer interferometry
Autoren: Alexander Mader Renate Kunert
Event: The new ParadIgM 2011 - IgM from bench to clinic
Year: 2011 - Anti-idiotypic antibody Ab2/3H6 mimicking gp41: a potential HIV-1 vaccine?
Autoren: Renate Kunert Alexander Mader
Event: 22nd meeting of the European Society for Animal Cell Technology ESACT 2011
Year: 2011 - 3D6 and 4B3: Recombinant expression of two anti-gp41 antibodies as dimeric and secretory IgA
Autoren: Reinhart, D; Weik, R; Kunert, R
Event: 22nd meeting of the European Society for Animal Cell Technology ESACT 2011
Year: 2011 - Humanization of the plant N-glycosylation pathway for the production of therapeutically relevant proteins
Autoren: Castilho, A., Gattinger, P., Pabst, M., Grass, J., Kunert, R., Strasser, R., Altmann, F., Steinkellner, H
Event: 21st International Symposium on Glycoconjugates GLYCO 21, 2011
Year: 2011 - Production and Purification of 3D6 and 4B3 as Recombinant Human IgA
Autoren: Reinhart, D; Kunert, R
Event: Annual Meeting EuroNeut-41 2011
Year: 2011 - Comparison of CHO host cell lines CHO-DUKX-B11 and CHO-DG44
Autoren: Urszula Puc Christian Leitner Renate Kunert
Event: 3rd ÖGMBT Annual Meeting 2011
Year: 2011 - Quantitative and qualitative analysis of erythropoietin-Fc production in a high density and glutamine-free adapted CHO cell line.
Autoren: Kumar N., Taschwer M., Hackl M., Bort JA., Pabst M., Grass J., Kunert R., Altmann F., Borth, N.
Event: 22nd meeting of the European Society for Animal Cell Technology ESACT 2011
Year: 2011 - Expression of pentameric IgMs to evaluate regulatory and environmental factors influencing IgM assembly and secretion
Autoren: Veronika Chromikova Willibald Steinfellner Marion Tschernutter Renate Kunert
Event: 3rd ÖGMBT Annual Meeting 2011
Year: 2011 - Recombinant human IgMs: Purification, characterization and modification
Autoren: Renate Kunert
Event: The new ParadIgM 2011 - IgM from bench to clinic
Year: 2011 - Developing monoclonal IgM-producing CHO cell lines for the purpose of further investigation of the product.
Autoren: Chromikova, V; Steinfellner, W; Tschernutter, M; Kunert, R
Event: 3rd ÖGMBT Annual Meeting 2011
Year: 2011 - 3D6 and 4B3: Recombinant expression of two anti-gp41 mAbs as dimeric and secretory IgA
Autoren: Reinhart, D; Weik, R; Kunert, R
Event: EUROPRISE Annual Conference 2011
Year: 2011 - Next-generation sequencing of the Chinese hamster ovary microRNA transcriptome: identification, annotation and profiling of miRNA as targets for cellular engineering.
Autoren: Hackl, M., Jakobi, T., Blom, J., Doppmeier, D., Brinkrolf, K., Szczepanowski, R., Bernhart, S., Höner zu Siederdissen, C., Bort, JA., Wieser, M., Kunert, R., Jeffs, S., Hofacker, I., Goesmann, A., Pühler, A., Borth, N, Grillari, J.
Event: 22nd meeting of the European Society for Animal Cell Technology ESACT 2011
Year: 2011 - Recombinant human IgMs: Purification, characterization and modification
Autoren: Renate Kunert
Event: The new ParadIgM 2011 - IgM from bench to clinic
Year: 2010 - The next generation of 3D6 and 4B3: Isotype switch of two NNAbs to dIgA and sIgA
Autoren: Reinhart, D; Tschernutter, M; Kunert, R
Event: EuroNeut-41 Discovery Meeting 2010
Year: 2010 - Recombinant expression of anti-gp41 antibodies as dimeric and secretory IgA
Autoren: Reinhart, D; Tschernutter, M; Kunert, R
Event: EUROPRISE Annual Conference 2010
Year: 2010 - Humanization variants of an anti-idiotypic antibody
Autoren: Renate Kunert, Alexander Mader, Hermann Katinger
Event: Human Antibodies and Hybridomas 2010
Year: 2009 - Approaches for humanization of an anti-idiotypic murine monoclonal antibody
Autoren: Alexander Mader, Hermann Katinger, Renate Kunert
Event: 21st Meeting of the European Society for Animal Cell Technology ESACT 2009
Year: 2009 - Glyco-engineering in plants: production of monoclonal antibodies containing homogeneously β1,4-galactosylated human-type N-glycans.
Autoren: Glössl, J., Strasser, R., Castilho, A., Kunert, R., Altmann, F., Mach, L., Steinkellner, H.
Event: GLYCOBIOLOGY 2009
Year: 2009 - Consistent1,4-galactosylation of monoclonal antibodies produced in plants.
Autoren: Castilho, A., Strasser, R., Stadlmann, J., Kunert, R., Gattinger, P., Altmann, F., Mach, L., Steinkellner, H
Event: 15th European Carbohydrate Symposium 2009
Year: 2008 - A study on the temperature dependency and time course of the cold capture secretion assay.
Autoren: Pichler, J., Hesse, F., Wieser, M., Kunert, R., Galosy, S., Mott, J.E., Borth, N.
Event: 11th International Conference Cell Culture Engineering 2008
Year: 2008 - Is Yeast or CHO system the superior expression system? A case study with a monoclonal Fab
Autoren: Renate Kunert
Event: Cell Line Development and Engineering 2008
Year: 2008 - Influence of different genetic parameters and regulatory sequences on recombinant expression of a monoclonal antibody
Autoren: Renate Kunert, H. Reisinger, W. Steinfellner, B. Stern, H. Katinger
Event: Human Antibodies and Hybridomas 2008
Year: 2008 - A study on the temperature dependency and time course of the cold capture secretion assay.
Autoren: Pichler, J., Hesse, F., Wieser, M., Kunert, R., Galosy, S., Mott, J.E., Borth, N.
Event: Cell Culture Engineering
Year: 2007 - Characterisation of cell behaviour by flow cytometry.
Autoren: Borth N., Hinterkörner G., Hesse F., Ezzenje K., Matej M., Kunert R., Katinger H.,
Event: 20th ESACT Meeting 2007
Year: 2007 - Transfection of serum-free CHO cells with chemically defined liposomes
Autoren: Reisinger Hannes, Vorauer-Uhl Karola, Steinfellner Willibald, Wagner Andreas, Katinger Hermann and Kunert Renate
Event: Bioprocess International European Conference 2007
Year: 2007 - Characterisation of cell behaviour by flow cytometry.
Autoren: Borth N., Hinterkörner G., Hesse F., Ezzenje K., Matej M., Kunert R., Katinger H.
Event: 20th ESACT Meeting 2007
Year: 2007 - Prologed bioactivity of nanovesicular protein targeting by enhanced depot effect
Autoren: Strobach, S., Wagner, A., Kunert, R., Katinger, H., Vorauer-Uhl, K.
Event: Bioprocess International European Conference 2007
Year: 2007 - Correlation between mitochondria-related fluorescent dyes and the energy metabolism in CHO cells
Autoren: Hinterkörner G., Pichler J., Hesse F., Kunert R., Katinger H., Borth N.
Event: 20th ESACT Meeting 2007
Year: 2007 - Correlation between mitochondria-related fluorescent dyes and the energy metabolism in CHO cells
Autoren: Hinterkörner G., Pichler J., Hesse F., Kunert R., Katinger H., Borth N.
Event: 20th ESACT Meeting 2007
Year: 2007 - Correlation between mitochondria-related fluorescent dyes and the energy metabolism in CHO cells.
Autoren: Hinterkörner G., Pichler J., Hesse F., Kunert R., Katinger H., Borth N.
Event: 20th ESACT Meeting 2007
Year: 2007 - Characterisation of cell behaviour by flow cytometry.
Autoren: Borth N., Hinterkörner G., Hesse F., Ezzenje K., Matej M., Kunert R., Katinger H.
Event: 20th ESACT Meeting 2007
Year: 2006 - Identification of Physiological Bottlenecks hampering Heterologous Protein Expression in Pichia pastoris by Genomic and Proteomic Analysis
Autoren: Dragosits M, Gasser B, Maurer M, Kunert R and Mattanovich D
Event: 3rd Summer School in Proteomic Basics 2006 - Exploring the Diversity of Proteins
Year: 2006 - Cell Line Development by Fluorescence Activated Cell Sorting
Autoren: Borth N., Brugger G., Hinterkörner G., Ernst W., Müller D., Hesse F., Kunert R., Katinger H.
Event: Engineering Foundation Cell Culture Engineering X
Year: 2006 - In vitro and in vivo characterization of an antiidiotypic antibody variants directed against the HIV-neutralizing mAb 2F5
Autoren: Kunert, R., Gach, J., Preis, S., Löschel M., Weik, R., Ferko, B., Stiegler, G., Gasser, B., Mattanivich, D., Katinger, H.
Event: Human Antibodies and Hybridomas 2006
Year: 2006 - High level expression of a humanised Ab2/3H6 Fab in Pichia pastoris.
Autoren: Gach, J.,Maurer, M., Quendler, H., Gasser, B., Löschel, M., Mattanovich, D., Katinger, H., Kunert, R.
Event: Recombinant Antibodies
Year: 2006 - Biphasic cultivation - A simple strategy to improve the space-time yield of CHO based bioprocesses without affecting product quality
Autoren: Müller, D.
Event: Post Translational Modifications
Year: 2006 - Encapsulation efficiency of lipid nano-vesicles for recombinant human Erythropoietin as a model protein
Autoren: Strohbach,St., Wagner,A., Kunert,R., Katinger,H., Vorauer-Uhl, K.
Event: ILS 2006 Annual Meeting
Year: 2006 - Serum-free transfections of CHO-cells with defined Small Unilamellar Vesicles
Autoren: Reisinger, H., Vorauer-Uhl, K., Wagner, A., Katinger, H., Kunert, R.,
Event: Cell Line Development and Engineering 2006
Year: 2006 - Encapsulation efficiency of lipid nano-vesicles for recombinant human Erythropoietin as a model protein
Autoren: Strohbach,St., Wagner,A., Kunert,R., Katinger,H., Vorauer-Uhl, K.
Event: ILS 2006 Annual Meeting
Year: 2005 - Product characterization of a recombinant glycoprotein by isoelectric focusing (Poster)
Autoren: Schriebl, K., Trummer, E., Lattenmayer, C., Müller, D., Hesse, F., Kunert, R., Katinger, H., Vorauer-Uhl, K.
Event: 19th ESACT Meeting 2005 - Cell Technology for Cell Products
Year: 2005 - Protein biopharmaceuticals from mammalian cell technology: from gene ti the master cell bank
Autoren: Renate Kunert, Willibald Steinfellner, Martina Löschel, Dethardt Müller, Christine Lattenmayer, Sonja Preis, Johannes Gach, Susanne Wolbank, Regina Voglauer, Hermann Katinger
Event: 60 Year Anniversary, Institute of Applied Microbiology IAM 2005
Year: 2005 - Analysis of genetic parameters in order to get more information on high producing recombinant CHO cell lines (Poster)
Autoren: Lattenmayer, C., Loeschel, M., Schriebl, K., Trummer, E., Vorauer-Uhl, K., Müller, D., Katinger, H., Kunert, R.
Event: 19th ESACT Meeting 2005 - Cell Technology for Cell Products
Year: 2005 - Improvement of the glycolytic metabolism in mammalian cells by fluorescence activated cell sorting
Autoren: Gudrun Brugger, Dethardt Müller, Renate Kunert, Friedemann Hesse, Hermann Katinger, Nicole Borth
Event: 60 Year Anniversary, Institute of Applied Microbiology IAM 2005
Year: 2005 - From gene to monoclonal antibody: efficient screening by cell sorting
Autoren: Borth N., Böhm E., Grillari J., Löscher M., Gross S., Voglauer R., Ferko B., Kunert R., Katinger H.
Event: Animal Cell Technology meets Genomics
Year: 2005 - Transcription profile analysis of different recombinant CHO clones based on cross species microarray analysis (Poster)
Autoren: Trummer, E., Ernst, W., Müller, D, Schriebl, K., Lattenmayer, C., Kunert, R., Vorauer-Uhl, K., Katinger, H., Hesse, F.
Event: 19th ESACT Meeting 2005 - Cell Technology for Cell Products
Year: 2005 - Improvement of the glycolytic metabolism in mammalian cells by fluorescence activated cell sorting
Autoren: Borth N., Brugger G., Müller D., Hesse D., Kunert R., Katinger H.
Event: 19th ESACT Meeting 2005 - Cell Technology for Cell Products
Year: 2005 - Anti-idiotypic antibodies, an alternatve strategy against HIV-1
Autoren: Johannes Gach, Boris Ferko, Brigitte Gasser, Diethardt Mattanovich, Hermann Katinger, Renate Kunert
Event: 60 Year Anniversary, Institute of Applied Microbiology IAM 2005
Year: 2005 - Protein Biopharmaceuticals from Mammalian Cell Technology: from the Gene to the Master Cell Bank
Autoren: Rnate Kunert
Event: 60 Year Anniversary, Institute of Applied Microbiology IAM 2005
Year: 2005 - From Gene to antibody: efficient screening by cell sorting.
Autoren: Ernst Böhm, Johannes Grillari, Martina Löschel, Stefan Gross, Regina Voglauer, Renate Kunert, Hermann Katinger, Nicole Borth
Event: 60 Year Anniversary, Institute of Applied Microbiology IAM 2005
Year: 2005 - Protein free transfection of CHO host cells with and IgG-fusion protein – selection and characterisation of stable high producers
Autoren: Christine Lattenmayer, Martina Löschel, Evelyn Trummer, Karola Vorauer-Uhl, Hermann Katinger, Renate Kunert
Event: 60 Year Anniversary, Institute of Applied Microbiology IAM 2005
Year: 2005 - Sorting for high producers: Methods and application
Autoren: Ernst Böhm, Max Zeyda, Willibald Steinfellner, Regina Voglauer, Renate Kunert, Hermann Katinger, Nicole Borth
Event: 60 Year Anniversary, Institute of Applied Microbiology IAM 2005
Year: 2005 - Effect of pH, DO and Temperature on the Performance of CHO Cells in a Batch Process (Poster)
Autoren: Trummer, E., Hesse, F., Seidinger, S., Fauland, K., Schriebl, K., Lattenmayer, C., Borth, N., Kunert, R., Vorauer-Uhl, K., Katinger, H., Müller, D.,
Event: 19th ESACT Meeting 2005 - Cell Technology for Cell Products
Year: 2005 - Protein biopharmaceuticals from mammalian cell technology: from the gene to the master cell bank
Autoren: Kunert, R., Steinfellner, W., Löschel, M., Müller, D., Lattenmayer, C., Preis, S., Gach, J., Wolbank, S., Voglauer, R., Katinger, H.
Event: 60 Year Anniversary, Institute of Applied Microbiology IAM 2005
Year: 2005 - Anti-idiotypic antibodies an alternative strategy against HIV-1
Autoren: Gach, J., Ferko, B., Gasser, B., Mattanovich, D., Katinger, H., Kunert, R.
Event: 60 Year Anniversary, Institute of Applied Microbiology IAM 2005
Year: 2005 - Optimisation of protein secretion in antibody fragment expressing Pichia pastoris
Autoren: Gasser B., Maurer M., Kunert R., Mattanovich D.
Event: 60 Year Anniversary, Institute of Applied Microbiology IAM 2005
Year: 2005 - Protein Free Transfection of CHO Host Cells with an IgG-Fusion Protein - Selection and Characterisation of Stable High Producers (Poster)
Autoren: Christine Lattenmayer, Martina Loeschel, Evelyn Trummer, Karola Vorauer-Uhl, Hermann Katinger, Renate Kunert
Event: 7th Conference on Protein Expression in Animal Cells PEACe 2005
Year: 2005 - Characterisation of CHO Subclones Showing Profound Changes in Performance when Propagated in Different Cultivation Systems (Poster)
Autoren: Trummer, E., Steinfellner, W., Kunert, R., Steindl, F., Hesse, F., Katinger, H., Müller, D.
Event: 60 Year Anniversary, Institute of Applied Microbiology IAM 2005
Year: 2004 - Anti-idiotypic antibody, Ab2b-3H6, against the neutralizing anti-HIV-antibody mimics the conserved env-epitope ELDKWA
Autoren: Gach, J., Preis, S., Steinfellner, W., Löschel, M., Weik, R., Ferko, B., Stiegler, G., Katinger, H. and Kunert, R.
Event: Human Antibodies and Hybridomas 2004
Year: 2004 - Comparison of protein profiles of different CHO cell lines
Autoren: Przewalla, C., Chang, M., Kunert, R., Hesse, F., Grillari, J., Borth, N., Katinger, H.
Event: 6th Siena meeting from genome to proteome 2004 - Biomarker discovery and proteome imaging
Year: 2004 - Effect of class switches of anti-HIV neutralizing mAbs expressed in CHO cells as IgG3, IgG1, IgM and IgA
Autoren: Kunert,R., Wolbank,S., Vorauer-Uhl,K., Stiegler,G., Vcelar,B., Katinger,H.
Event: Cell Culture and Upstream Processing
Year: 2004 - Effect of increased levels of Protein Disulfide Isomerase and BiP/GRP78 on human antibody productivity in recombinant CHO cells
Autoren: Borth N, Mattanovich D., Kunert R, Katinger H.
Event: Cell Culture Engineering IX, Engineering Foundation Conference
Year: 2003 - Comparison of fluidized bed and fed-batch reactor cultures for production of anti-HIV antibody
Autoren: Hinterleitner, P., Unterluggauer, F., Landauer, K., Müller, D., Kunert, R., Blüml, G., Doblhoff-Dier, O., Katinger, H.
Event: 18th ESACT Meeting 2003 - Animal Cell Technology Meets Genomics
Year: 2003 - Control of Key Parameters in the Development of mammalian production clones
Autoren: Kunert R., Preis S., Steinfellner W., Assadian A., Borth N., Müller D., Katinger H.
Event: 18th ESACT Meeting 2003 - Animal Cell Technology Meets Genomics
Year: 2003 - Efficient Selection of Antigen Specific Hybridomas by Cell Sorting using a Single Cell Secretion Assay
Autoren: Borth N., Böhm E., Grillari J., Voglauer R., Kunert R., Gross S., Ferko B., Katinger H.
Event: 18th ESACT Meeting 2003 - Animal Cell Technology Meets Genomics
Year: 2003 - Characterisation of CHO subclones showing profound changes in performance when propagated in different cultivation systems
Autoren: Trummer, E., Müller, D., Steinfellner, W., Kunert, R., Steindl, F., Hesse, F., Katinger, H
Event: 18th ESACT Meeting 2003 - Animal Cell Technology Meets Genomics
Year: 2003 - From gene to monoclonal antibody: efficient screening by cell sorting
Autoren: Borth, N., Böhm, E., Grillari, J., Löscher, M., Gross, S., Voglauer, R., Ferko, B., Kunert, R., Katinger, H.
Event: 18th ESACT Meeting 2003 - Animal Cell Technology Meets Genomics
Year: 2003 - Effiziente Selektion von hochproduzierenden tierischen Zelllinien für die Produktion von biopharmazeutischen Produkten mit dem Zellsorter
Autoren: Borth N., Böhm E., Voglauer R., Kunert R., Katinger H.
Event: Jahrestagung der Österreichischen Geselschaft für Flow Zytometrie
Year: 2002 - Efficient Selection of monoclonal, antigen-specific and high-producing Hybridoma Cell Lines in a Single Cloning Step by Flow Cytometry and Cell Sorting.
Autoren: Böhm, E., Borth, N., Voglauer, R., Stiegler, G., Hahn, R., Ferko, B., Kunert, R., Katinger, H.
Event: UEF Cell Culture Engineering Conference
Year: 2002 - Efficient selection of monoclonal, antigen-specific and high-producing hybridoma cell lines by flow cytometry and cell sorting: in a single cloning step ?
Autoren: Böhm, E., Borth, N., Voglauer, R., Kunert, R., Ferko, B., Wiederkum, S., Stiegler, G., Hahn, R., Katinger, H.
Event: ISAC 2002 XXI Congress of the International Society for Analytical Cytology
Year: 2002 - Expression von Glykoproteinen in rekombinanten CHO-Zellen
Autoren: R. Kunert, D. Müller, N. Borth, R. Weik, H. Katinger
Event: Österreichische Gesellschaft für Zellkultur und European Tissue Culture Society: Neues aus der Zell- und Gewebekultur
Year: 2002 - Establishment of human cell lines expressing human Erythropoietin.
Autoren: Voglauer, R., Kunert, R., Steinfellner, W., Katinger, H.
Event: Joint annual meeting of the Österreichische Gesellschaft für Biotechnologie ÖGBM, ÖGGGT, ÖGBT and ANGT 2002
Year: 2002 - Control of key parameters in the development of mammalian production clones
Autoren: R. Kunert, S. Wolbank, D. Müller, R. Voglauer, N. Borth, H. Katinger
Event: Unknown
Year: 2002 - Screening for Additional Cell Properties: Selection of Subclones with Altered Production Kinetics or Improved Stability by Cell Sorting using an Affinity Matrix Secretion Assay
Autoren: Borth, N., Böhm, E., Voglauer, R., Steinfellner, W., Kunert, R., Katinger, H.
Event: UEF Cell Culture Engineering Conference
Year: 2002 - Antibody secreting cell lines as model systems for affinity matrix secretion assay based cell sorting.
Autoren: Böhm, E., Voglauer, R., Kunert, R., Grillari, J., Gross, S., Ferko, B., Katinger, H., Borth, N.
Event: 15th Heidelberg Cytometry Symposium (HCS) Annual Meeting of the German Society of Cytometry (DGfZ)
Year: 2002 - Mouse/human anti-idiotypic antibodies and chimeric fusion proteins mimicking neutralizing HIV-antigens (Poster)
Autoren: Christine Lattenmayer, Renate Kunert, Sonja Preis, Gabriela Stiegler, Robert Weik, Boris Ferko, Hermann Katinger
Event: 2nd International conference on Recombinant protein production 2002 - A comparative view on host physiology
Year: 2001 - Die Entwicklung klinischer Biopharmaka mittels nativer und rekombinanter Eukaryonten
Autoren: Kunert,R., Vorauer-Uhl,K., Borth,N., Katinger,H.
Event: Hochschullehrer-Nachwuchstreffen der DECHEMA
Year: 2001 - Continuous Perfusion versus Discontinous Fed-Batch (oral presentation)
Autoren: Müller, D., G. Simic, W. Steinfellner, R. Keijzer, R. Kunert, E. Benes, M. Gröschl, F. Trampler, O. Doblhoff-Dier and H. Katinger
Event: 17th ESACT Meeting 2001. Animal Cell Technology: From Target to Market
Year: 2001 - Efficient and Rapid Clone Selection of Human-Antibody Producing Xenohybridomas by Flow Cytometry and Cell Sorting According to Single Cell Specific Production Rate.
Autoren: Böhm, E., Borth, N., Voglauer, R., Wiederkum, S., Kunert, R., Katinger, H.
Event: Human Antibodies and Hybridomas 2001
Year: 2000 - Maintenance of a high antibody expression level in CHO cells without selective and amplification pressure by cell sorting
Autoren: Böhm, E., Borth, N., Voglauer, R., Kunert, R., Steinfellner, W., Katinger, H.
Event: ISAC congress XX
Year: 2000 - Establishment of recombinant CHO for industrial protein production
Autoren: R.Kunert, K.Strutzenberger, F.Steindl, G.Vecera, A.Zudjelovic, N.Borth, H.Katinger
Event: Recombinant Protein Production with prokaryotic and eukaryotic cells 2000 - A comparative view on host physiology
Year: 2000 - Analysis of oncogene expression and chromosomal stability of SV40 early region transfected (ISAC congress XX,
Autoren: Voglauer, R., Kunert, R., Hohenwarter, O., Böhm, E., Borth, N., Katinger, H.
Event: ISAC congress XX
Year: 1999 - Analysis of genomic DNA and RNA-Transcripts of a heterohybridoma simultanously expressing IgG3 and IgG1 with identical specificity.
Autoren: Kunert, R., S. Wolbank, A. Hüser and H. Katinger
Event: 16th ESACT-Meeting 1999. Animal Cell Technology: Products from Cells, Cells as Products
Year: 1999 - Stable recombinant expression and functional identity of the antio HIV-1 monoclonal antibody 2F5 after IgG3/IgG1 subclass switch in CHO-cells
Autoren: Kunert, R., W. Steinfellner, A. Assadian and H. Katinger
Event: 16th ESACT-Meeting 1999. Animal Cell Technology: Products from Cells, Cells as Products