Cavinato, M; Madreiter-Sokolowski, CT; Büttner, S; Schosserer, M; Zwerschke, W; Wedel, S; Grillari, J; Graier, WF; Jansen-Dürr, P; :
Targeting cellular senescence based on interorganelle communication, multilevel proteostasis, and metabolic control.
FEBS J. 2021; 288(12):3834-3854, 2021
Gludovacz, E; Schuetzenberger, K; Resch, M; Tillmann, K; Petroczi, K; Schosserer, M; Vondra, S; Vakal, S; Klanert, G; Pollheimer, J; Salminen, TA; Jilma, B; Borth, N; Boehm, T; :
Heparin-binding motif mutations of human diamine oxidase allow the development of a first-in-class histamine-degrading biopharmaceutical.
Elife. 2021; 10:, 2021
Liendl, L; Schosserer, M; :
Raman microspectroscopy: sub-cellular chemical imaging of aging.
Aging (Albany NY). 2021; 13(23):24922-24923, 2021
Narzt, MS; Pils, V; Kremslehner, C; Nagelreiter, IM; Schosserer, M; Bessonova, E; Bayer, A; Reifschneider, R; Terlecki-Zaniewicz, L; Waidhofer-Söllner, P; Mildner, M; Tschachler, E; Cavinato, M; Wedel, S; Jansen-Dürr, P; Nanic, L; Rubelj, I; El-Ghalbzouri, A; Zoratto, S; Marchetti-Deschmann, M; Grillari, J; Gruber, F; Lämmermann, I; :
Epilipidomics of Senescent Dermal Fibroblasts Identify Lysophosphatidylcholines as Pleiotropic Senescence-Associated Secretory Phenotype (SASP) Factors.
J Invest Dermatol. 2021; 141(4S):993-1006.e15, 2021
Pils, V; Terlecki-Zaniewicz, L; Schosserer, M; Grillari, J; Lämmermann, I; :
The role of lipid-based signalling in wound healing and senescence.
Mech Ageing Dev. 2021; 198:111527, 2021
Schwarze, UY; Ni, Y; Zhou, Y; Terlecki-Ζaniewicz, L; Schosserer, M; Hackl, M; Grillari, J; Gruber, R; :
Size changes in miR‑21 knockout mice: Geometric morphometrics on teeth, alveolar bone and mandible.
Mol Med Rep. 2021; 23(4):1-7, 2021
Gonskikh, Y; Gerstl, M; Kos, M; Borth, N; Schosserer, M; Grillari, J; Polacek, N; :
Modulation of mammalian translation by a ribosome-associated tRNA half.
RNA Biol. 2020; 17(8):1125-1136, 2020
Gruber, F; Marchetti-Deschmann, M; Kremslehner, C; Schosserer, M; :
The Skin Epilipidome in Stress, Aging, and Inflammation.
Front Endocrinol (Lausanne). 2020; 11:607076, 2020
Heissenberger, C; Rollins, JA; Krammer, TL; Nagelreiter, F; Stocker, I; Wacheul, L; Shpylovyi, A; Tav, K; Snow, S; Grillari, J; Rogers, AN; Lafontaine, DLJ; Schosserer, M; :
The ribosomal RNA m 5 C methyltransferase NSUN-1 modulates healthspan and oogenesis in Caenorhabditis elegans
Elife. 2020; 9:, 2020
Kremslehner, C; Miller, A; Nica, R; Nagelreiter, IM; Narzt, MS; Golabi, B; Vorstandlechner, V; Mildner, M; Lachner, J; Tschachler, E; Ferrara, F; Klavins, K; Schosserer, M; Grillari, J; Haschemi, A; Gruber, F; :
Imaging of metabolic activity adaptations to UV stress, drugs and differentiation at cellular resolution in skin and skin equivalents - Implications for oxidative UV damage.
Redox Biol. 2020; 37:101583, 2020
Liendl, L; Grillari, J; Schosserer, M; :
Raman fingerprints as promising markers of cellular senescence and aging.
Geroscience. 2020; 42(2):-387, 2020
Strauss, FJ; Stähli, A; Kobatake, R; Tangl, S; Heimel, P; Apaza Alccayhuaman, KA; Schosserer, M; Hackl, M; Grillari, J; Gruber, R; :
miRNA-21 deficiency impairs alveolar socket healing in mice.
J Periodontol. 2020; 91(12):1664-1672, 2020
Weinmüllner, R; Zbiral, B; Becirovic, A; Stelzer, EM; Nagelreiter, F; Schosserer, M; Lämmermann, I; Liendl, L; Lang, M; Terlecki-Zaniewicz, L; Andriotis, O; Mildner, M; Golabi, B; Waidhofer-Söllner, P; Schedle, K; Emsenhuber, G; Thurner, PJ; Tschachler, E; Gruber, F; Grillari, J; :
Organotypic human skin culture models constructed with senescent fibroblasts show hallmarks of skin aging.
NPJ Aging Mech Dis. 2020; 6:4, 2020
Adamla, F; Rollins, J; Newsom, M; Snow, S; Schosserer, M; Heissenberger, C; Horrocks, J; Rogers, AN; Ignatova, Z; :
A Novel Caenorhabditis Elegans Proteinopathy Model Shows Changes in mRNA Translational Frameshifting During Aging.
Cell Physiol Biochem. 2019; 52(5):970-983, 2019
Heissenberger, C; Liendl, L; Nagelreiter, F; Gonskikh, Y; Yang, G; Stelzer, EM; Krammer, TL; Micutkova, L; Vogt, S; Kreil, DP; Sekot, G; Siena, E; Poser, I; Harreither, E; Linder, A; Ehret, V; Helbich, TH; Grillari-Voglauer, R; Jansen-Dürr, P; Koš, M; Polacek, N; Grillari, J; Schosserer, M; :
Loss of the ribosomal RNA methyltransferase NSUN5 impairs global protein synthesis and normal growth.
Nucleic Acids Res. 2019; 47(22):11807-11825, 2019
Schosserer, M; Banks, G; Dogan, S; Dungel, P; Fernandes, A; Marolt Presen, D; Matheu, A; Osuchowski, M; Potter, P; Sanfeliu, C; Tuna, BG; Varela-Nieto, I; Bellantuono, I; :
Modelling physical resilience in ageing mice.
Mech Ageing Dev. 2019; 177:91-102, 2019
Terlecki-Zaniewicz, L; Pils, V; Bobbili, MR; Lämmermann, I; Perrotta, I; Grillenberger, T; Schwestka, J; Weiß, K; Pum, D; Arcalis, E; Schwingenschuh, S; Birngruber, T; Brandstetter, M; Heuser, T; Schosserer, M; Morizot, F; Mildner, M; Stöger, E; Tschachler, E; Weinmüllner, R; Gruber, F; Grillari, J; :
Extracellular Vesicles in Human Skin: Cross-Talk from Senescent Fibroblasts to Keratinocytes by miRNAs.
J Invest Dermatol. 2019; 139(12):-2436.e5, 2019
Barwari, T; Eminaga, S; Mayr, U; Lu, R; Armstrong, PC; Chan, MV; Sahraei, M; Fernández-Fuertes, M; Moreau, T; Barallobre-Barreiro, J; Lynch, M; Yin, X; Schulte, C; Baig, F; Pechlaner, R; Langley, SR; Zampetaki, A; Santer, P; Weger, M; Plasenzotti, R; Schosserer, M; Grillari, J; Kiechl, S; Willeit, J; Shah, AM; Ghevaert, C; Warner, TD; Fernández-Hernando, C; Suárez, Y; Mayr, M; :
Inhibition of profibrotic microRNA-21 affects platelets and their releasate.
JCI Insight. 2018; 3(21):, 2018
Cardoso, AL; Fernandes, A; Aguilar-Pimentel, JA; de Angelis, MH; Guedes, JR; Brito, MA; Ortolano, S; Pani, G; Athanasopoulou, S; Gonos, ES; Schosserer, M; Grillari, J; Peterson, P; Tuna, BG; Dogan, S; Meyer, A; van Os, R; Trendelenburg, AU; :
Towards frailty biomarkers: Candidates from genes and pathways regulated in aging and age-related diseases.
Ageing Res Rev. 2018; 47:214-277, 2018
Hager, S; Korbula, K; Bielec, B; Grusch, M; Pirker, C; Schosserer, M; Liendl, L; Lang, M; Grillari, J; Nowikovsky, K; Pape, VFS; Mohr, T; Szakács, G; Keppler, BK; Berger, W; Kowol, CR; Heffeter, P; :
The thiosemicarbazone Me2NNMe2 induces paraptosis by disrupting the ER thiol redox homeostasis based on protein disulfide isomerase inhibition
Cell Death Dis. 2018; 9(11):1052, 2018
Lämmermann, I; Terlecki-Zaniewicz, L; Weinmüllner, R; Schosserer, M; Dellago, H; de Matos Branco, AD; Autheried, D; Sevcnikar, B; Kleissl, L; Berlin, I; Morizot, F; Lejeune, F; Fuzzati, N; Forestier, S; Toribio, A; Tromeur, A; Weinberg, L; Higareda Almaraz, JC; Scheideler, M; Rietveld, M; El Ghalbzouri, A; Tschachler, E; Gruber, F; Grillari, J; :
Blocking negative effects of senescence in human skin fibroblasts with a plant extract.
NPJ Aging Mech Dis. 2018; 4:4, 2018
Schosserer, M; Grillari, J; Wolfrum, C; Scheideler, M; :
Age-Induced Changes in White, Brite, and Brown Adipose Depots: A Mini-Review.
Gerontology. 2018; 64(3):229-236, 2018
Terlecki-Zaniewicz, L; Lämmermann, I; Latreille, J; Bobbili, MR; Pils, V; Schosserer, M; Weinmüllner, R; Dellago, H; Skalicky, S; Pum, D; Almaraz, JCH; Scheideler, M; Morizot, F; Hackl, M; Gruber, F; Grillari, J; :
Small extracellular vesicles and their miRNA cargo are anti-apoptotic members of the senescence-associated secretory phenotype.
Aging (Albany NY). 2018; 10(5):110-1132, 2018
Weinmuellner, R; Kryeziu, K; Zbiral, B; Tav, K; Schoenhacker-Alte, B; Groza, D; Wimmer, L; Schosserer, M; Nagelreiter, F; Rösinger, S; Mildner, M; Tschachler, E; Grusch, M; Grillari, J; Heffeter, P; :
Long-term exposure of immortalized keratinocytes to arsenic induces EMT, impairs differentiation in organotypic skin models and mimics aspects of human skin derangements.
Arch Toxicol. 2018; 92(1):181-194, 2018
Garschall, K; Dellago, H; Gáliková, M; Schosserer, M; Flatt, T; Grillari, J; :
Erratum: Ubiquitous overexpression of the DNA repair factor dPrp19 reduces DNA damage and extends Drosophila life span.
NPJ Aging Mech Dis. 2017; 3:10, 2017
Grillari, J; Weinmullner, R; Kryeziu, K; Zbiral, B; Tav, K; Schoenhacker-Alte, B; Groza, D; Schosserer, M; Nagelreiter, F; Rosinger, S; Mildner, M; Tschachler, E; Grusch, M; Heffeter, P:
Long-term exposure of immortalized keratinocytes to arsenic induces EMT, impairs differentiation in organotypic skin models and mimics aspects of human skin derangements
TOXICOL LETT. 2017; 280: S314-S314. , 2017
Khan, A; Dellago, H; Terlecki-Zaniewicz, L; Karbiener, M; Weilner, S; Hildner, F; Steininger, V; Gabriel, C; Mück, C; Jansen-Dürr, P; Hacobian, A; Scheideler, M; Grillari-Voglauer, R; Schosserer, M; Grillari, J; :
SNEV(hPrp19/hPso4) Regulates Adipogenesis of Human Adipose Stromal Cells.
Stem Cell Reports. 2017; 8(1):21-29, 2017
Prats Mateu, B; Harreither, E; Schosserer, M; Puxbaum, V; Gludovacz, E; Borth, N; Gierlinger, N; Grillari, J; :
Label-free live cell imaging by Confocal Raman Microscopy identifies CHO host and producer cell lines.
Biotechnol J. 2017; 12(1):, 2017
Schosserer, M; Grillari, J; Breitenbach, M; :
The Dual Role of Cellular Senescence in Developing Tumors and Their Response to Cancer Therapy.
Front Oncol. 2017; 7:278, 2017
Schosserer, M; Minois, N; Angerer, TB; Amring, M; Dellago, H; Harreither, E; Calle-Perez, A; Pircher, A; Peter Gerstl, M; Pfeifenberger, S; Brandl, C; Sonntagbauer, M; Kriegner, A; Linder, A; Weinhäusel, A; Mohr, T; Steiger, M; Mattanovich, D; Rinnerthaler, M; Karl, T; Sharma, S; Entian, KD; Kos, M; Breitenbach, M; Wilson, IB; Polacek, N; Grillari-Voglauer, R; Breitenbach-Koller, L; Grillari, J; :
Corrigendum: Methylation of ribosomal RNA by NSUN5 is a conserved mechanism modulating organismal lifespan.
Nat Commun. 2016; 7:11530, 2016
Schosserer, M; Minois, N; Angerer, TB; Amring, M; Dellago, H; Harreither, E; Calle-Perez, A; Pircher, A; Gerstl, MP; Pfeifenberger, S; Brandl, C; Sonntagbauer, M; Kriegner, A; Linder, A; Weinhäusel, A; Mohr, T; Steiger, M; Mattanovich, D; Rinnerthaler, M; Karl, T; Sharma, S; Entian, KD; Kos, M; Breitenbach, M; Wilson, IB; Polacek, N; Grillari-Voglauer, R; Breitenbach-Koller, L; Grillari, J; :
Methylation of ribosomal RNA by NSUN5 is a conserved mechanism modulating organismal lifespan.
Nat Commun. 2015; 6:6158, 2015
Schosserer, M; Reynoso, R; Wally, V; Jug, B; Kantner, V; Weilner, S; Buric, I; Grillari, J; Bauer, JW; Grillari-Voglauer, R; :
Urine is a novel source of autologous mesenchymal stem cells for patients with epidermolysis bullosa.
BMC Res Notes. 2015; 8(1):767, 2015
Dellago, H; Preschitz-Kammerhofer, B; Terlecki-Zaniewicz, L; Schreiner, C; Fortschegger, K; Chang, MW; Hackl, M; Monteforte, R; Kühnel, H; Schosserer, M; Gruber, F; Tschachler, E; Scheideler, M; Grillari-Voglauer, R; Grillari, J; Wieser, M; :
High levels of oncomiR-21 contribute to the senescence-induced growth arrest in normal human cells and its knock-down increases the replicative lifespan.
Aging Cell. 2013; 12(3):446-458, 2013
Loscher, M; Schosserer, M; Dausse, E; Lee, K; Ajuh, P; Grillari-Voglauer, R; Lamond, AI; Toulme, JJ; Grillari, J:
Inhibition of Pre-mRNA Splicing by a Synthetic Blom7 alpha-Interacting Small RNA
PLOS ONE. 2012; 7(10):, 2012