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Laurent Elisabeth

= Open Access - Publikationen

2021

Originalbeitrag in Fachzeitschrift

** Capraz, T; Kienzl, NF; Laurent, E; Perthold, JW; Föderl-Höbenreich, E; Grünwald-Gruber, C; Maresch, D; Monteil, V; Niederhöfer, J; Wirnsberger, G; Mirazimi, A; Zatloukal, K; Mach, L; Penninger, JM; Oostenbrink, C; Stadlmann, J; Structure-guided glyco-engineering of ACE2 for improved potency as soluble SARS-CoV-2 decoy receptor..

** Castilho, A; Schwestka, J; Kienzl, NF; Vavra, U; Grünwald-Gruber, C; Izadi, S; Hiremath, C; Niederhöfer, J; Laurent, E; Monteil, V; Mirazimi, A; Wirnsberger, G; Stadlmann, J; Stöger, E; Mach, L; Strasser, R; Generation of enzymatically competent SARS-CoV-2 decoy receptor ACE2-Fc in glycoengineered Nicotiana benthamiana..

** Laurent, E; Sieber, A; Salzer, B; Wachernig, A; Seigner, J; Lehner, M; Geyeregger, R; Kratzer, B; Jäger, U; Kunert, R; Pickl, WF; Traxlmayr, MW; Directed Evolution of Stabilized Monomeric CD19 for Monovalent CAR Interaction Studies and Monitoring of CAR-T Cell Patients..

** Schwestka, J; König-Beihammer, J; Shin, YJ; Vavra, U; Kienzl, NF; Grünwald-Gruber, C; Maresch, D; Klausberger, M; Laurent, E; Stadler, M; Manhart, G; Huber, J; Hofner, M; Vierlinger, K; Weinhäusel, A; Swoboda, I; Binder, CJ; Gerner, W; Grebien, F; Altmann, F; Mach, L; Stöger, E; Strasser, R; Impact of Specific .

** Shin, YJ; Konig-Beihammer, J; Vavra, U; Schwestka, J; Kienzl, NF; Klausberger, M; Laurent, E; Grunwald-Gruber, C; Vierlinger, K; Hofner, M; Margolin, E; Weinhausel, A; Stoger, E; Mach, L; Strasser, R N-Glycosylation of the SARS-CoV-2 Receptor Binding Domain Is Important for Functional Expression in Plants.

PUBLIZIERTER Beitrag für wissenschaftliche Veranstaltung

** Gudipati, V; Rydzek, J; Perez, ID; Goncalves, VDR; Scharf, L; Konigsberger, S; Lobner, E; Kunert, R; Einsele, H; Stockinger, H; Hudecek, M; Huppa, JB Inefficient CAR-proximal signaling blunts antigen sensitivity.

2020

Originalbeitrag in Fachzeitschrift

** Gudipati, V; Rydzek, J; Doel-Perez, I; Goncalves, VD; Scharf, L; Konigsberger, S; Lobner, E; Kunert, R; Einsele, H; Stockinger, H; Hudecek, M; Huppa, JB Inefficient CAR-proximal signaling blunts antigen sensitivity.

** Lobner, E; Wachernig, A; Gudipati, V; Mayrhofer, P; Salzer, B; Lehner, M; Huppa, JB; Kunert, R Getting CD19 Into Shape: Expression of Natively Folded "Difficult-to- Express" CD19 for Staining and Stimulation of CAR-T Cells.

** Puchol Tarazona, AA; Lobner, E; Taubenschmid, Y; Paireder, M; Torres Acosta, JA; Göritzer, K; Steinkellner, H; Mach, L; Steric Accessibility of the Cleavage Sites Dictates the Proteolytic Vulnerability of the Anti-HIV-1 Antibodies 2F5, 2G12, and PG9 in Plants..

** Salzer, B; Schueller, CM; Zajc, CU; Peters, T; Schoeber, MA; Kovacic, B; Buri, MC; Lobner, E; Dushek, O; Huppa, JB; Obinger, C; Putz, EM; Holter, W; Traxlmayr, MW; Lehner, M Engineering AvidCARs for combinatorial antigen recognition and reversible control of CAR function.

2019

PUBLIZIERTER Beitrag für wissenschaftliche Veranstaltung

** Salzer, B; Brey, CU; Schueller, C; Schoeber, M; Lobner, E; Dushek, O; Holter, W; Traxlmayr, MW; Lehner, M AVIDCARS - A NOVEL PLATFORM FOR INTEGRATION OF MULTIPLE INPUT SIGNALS BY ONE CAR MOLECULE.
[International Conference on Lymphocyte Engineering (ICLE), London, UK, 13.09.2019 - 15.09.2019]

2017

Originalbeitrag in Fachzeitschrift

** Lobner, E; Humm, AS; Göritzer, K; Mlynek, G; Puchinger, MG; Hasenhindl, C; Rüker, F; Traxlmayr, MW; Djinović-Carugo, K; Obinger, C; Fcab-HER2 Interaction: a Ménage à Trois. Lessons from X-Ray and Solution Studies..

** Lobner, E; Humm, AS; Mlynek, G; Kubinger, K; Kitzmüller, M; Traxlmayr, MW; Djinović-Carugo, K; Obinger, C; Two-faced Fcab prevents polymerization with VEGF and reveals thermodynamics and the 2.15 Å crystal structure of the complex..

2016

** Lobner, E; Traxlmayr, MW; Obinger, C; Hasenhindl, C; Engineered IgG1-Fc--one fragment to bind them all..

** Traxlmayr, MW; Kiefer, JD; Srinivas, RR; Lobner, E; Tisdale, AW; Mehta, NK; Yang, NJ; Tidor, B; Wittrup, KD Strong Enrichment of Aromatic Residues in Binding Sites from a Charge-neutralized Hyperthermostable Sso7d Scaffold Library.

PUBLIZIERTER Beitrag für wissenschaftliche Veranstaltung

Lobner, E., Humm, A.-S., Göritzer, K., Mlynek, G., Hasenhindl, C., Traxlmayr, M., Djinoviv-Carugo, K., Obinger, C. (2016): Structures and thermodynamics of Fcab-antigen complexes.. [Poster]
[PEGS 2016, Boston, MA, USA, 25.04.2016 - 29.04.2016]

Traxlmayr, MW; Kiefer, JD; Srinivas, RR; Lobner, E; Tisdale, AW; Mehta, NK; Tidor, B; Wittrup KD (2016): A hyperstable miniprotein as an alternative to antibodies.
[8th ÖGMBT Annual Meeting 2016, Graz, Austria, 12.09.2016 - 14.09.2016]

2015

Lobner, E., Humm, A.-S., Göritzer, K., Hasenhindl, H., Djinovic-Carugo, K., and Obinger, C. (2015): Recombinant production and structural characterization of Fcabs.
[8th Conference on Recombinant Protein Production RPP8 2015, Palma de Mallorca, Spain, 22.04.2015 - 24.04.2015]

2014

Originalbeitrag in Fachzeitschrift

** Traxlmayr, MW; Lobner, E; Hasenhindl, C; Stadlmayr, G; Oostenbrink, C; Rüker, F; Obinger, C; Construction of pH-sensitive Her2-binding IgG1-Fc by directed evolution..

PUBLIZIERTER Beitrag für wissenschaftliche Veranstaltung

** Lobner, E; Traxlmayr, M; Ruker, F; Obinger, C Construction of pH-sensitive Her2 binding antibody fragment by directed evolution using yeast display.

** Traxlmayr, MW; Srinivas, RR; Lobner, E; Tidor, B; Wittrup, KD A Hyperstable Minimalist Protein for Molecular Recognition.
[28th Annual Symposium of the Protein-Society, San Diego, CA, USA, 27.07.2014 - 30.07.2014]

Lobner, E., Traxlmayr, M. W., Rueker, F., Obinger, C. (2014): Construction of pH-sensitive Her2 binding antibody fragment by directed evolution using yeast display. [Poster]
[The 16th European Congress on Biotechnology, Edinburgh, Scotland, UK, 13.07.2014 - 16.07.2014]

Lobner, E., Traxlmayr, M. W., Rüker, F., Obinger, C. (2014): Directed evolution of antibody fragments for improved stability and resistance to aggregation by using yeast surface display. [Poster]
[Human Antibodies and Hybridomas Conference 2014, Vienna, Austria, 31.03.2014 - 02.04.2014]

2013

Originalbeitrag in Fachzeitschrift

** Traxlmayr, MW; Lobner, E; Antes, B; Kainer, M; Wiederkum, S; Hasenhindl, C; Stadlmayr, G; Rüker, F; Woisetschläger, M; Moulder, K; Obinger, C; Directed evolution of Her2/neu-binding IgG1-Fc for improved stability and resistance to aggregation by using yeast surface display..

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