** Marx, N; Eisenhut, P; Weinguny, M; Klanert, G; Borth, N; How to train your cell - Towards controlling phenotypes by harnessing the epigenome of Chinese hamster ovary production cell lines..
Biotechnol Adv. 2022; 56:107924 WoS PubMed FullText FullText_BOKU** Szeliova, D; Stor, J; Thiel, I; Weinguny, M; Hanscho, M; Lhota, G; Borth, N; Zanghellini, J; Ruckerbauer, DE; Rocha, I Inclusion of maintenance energy improves the intracellular flux predictions of CHO.
** Weinguny, M; Klanert, G; Eisenhut, P; Lee, I; Timp, W; Borth, N Subcloning induces changes in the DNA-methylation pattern of outgrowing Chinese hamster ovary cell colonies.
BIOTECHNOL J. 2021; 16(6), e2000350 WoS PubMed FullText FullText_BOKU** Eisenhut, P; Mebrahtu, A; Barzadd, MM; Thalen, N; Klanert, G; Weinguny, M; Sandegren, A; Su, C; Hatton, D; Borth, N; Rockberg, J Systematic use of synthetic 5 '-UTR RNA structures to tune protein translation improves yield and quality of complex proteins in mammalian cell factories.
** Weinguny, M; Eisenhut, P; Klanert, G; Virgolini, N; Marx, N; Jonsson, A; Ivansson, D; Lovgren, A; Borth, N Random epigenetic modulation of CHO cells by repeated knockdown of DNA methyltransferases increases population diversity and enables sorting of cells with higher production capacities.
** Weinguny, M; Klanert, G; Eisenhut, P; Jonsson, A; Ivansson, D; Lovgren, A; Borth, N Directed evolution approach to enhance efficiency and speed of outgrowth during single cell subcloning of Chinese Hamster Ovary cells.
** Eisenhut, P; Klanert, G; Weinguny, M; Baier, L; Jadhav, V; Ivansson, D; Borth, N A CRISPR/Cas9 based engineering strategy for overexpression of multiple genes in Chinese hamster ovary cells.
** Eisenhut, P; Klanert, G; Weinguny, M; Baier, L; Jadhav, V; Ivansson, D; Borth, N A CRISPR/Cas9 based engineering strategy for overexpression of multiple genes in Chinese hamster ovary cells.
NEW BIOTECHNOL. 2018; 44: S145-S145. WoS FullText FullText_BOKU** Klanert, C; Daniel, F; Weinguny, M; Eisenhut, P; Bhler, E; Melcher, M; Titus, S; Jadhav, V; Su, X; Beate, S; Lal-Nag, M; Shiloach, J; Borth, N Identifying new engineering targets in Chinese hamster ovary cells.
NEW BIOTECHNOL. 2018; 44: S145-S145. WoS FullText FullText_BOKU