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Kunert Renate

Publikationen

Unter PUBLIKATIONEN werden die wissenschaftlichen Publikationen der BOKU Forscher und BOKU Forscherinnen gelistet, insbesondere Veröffentlichungen in SCI- / SSCI-gelisteten und in anderen referierten Fachzeitschriften. Weiters Beiträge in Sammelwerken, Proceedings sowie Monographien.

Wissenschaftliche Veröffentlichungen mit besonderem Fokus auf Wissenstransfer ("gesellschaftlicher Impakt") an Anwender, Praxisakteure sowie die interessierte Öffentlichkeit finden Sie nun unter dem NEUEN Menüpunkt:

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** = Publikationen gelistet in SCI/SSCI (veröffentlicht im Web of Science)
* = Publikationen in sonstigen peer-reviewten Journalen (ggf. noch nicht im WoS veröffentlicht)
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= Open Access - Publikationen

2022

Originalbeitrag in Fachzeitschrift

** Chouquet, A; Pinto, AJ; Hennicke, J; Ling, WL; Bally, I; Schwaigerlehner, L; Thielens, NM; Kunert, R; Reiser, JB Biophysical Characterization of the Oligomeric States of Recombinant Immunoglobulins Type-M and Their C1q-Binding Kinetics by Biolayer Interferometry.

FRONT BIOENG BIOTECH. 2022; 10, 816275 WoS PubMed FullText FullText_BOKU

** Garner-Spitzer, E; Wagner, A; Kundi, M; Stockinger, H; Ohradanova-Repic, A; Gebetsberger, L; Schoetta, AM; Gudipati, V; Huppa, JB; Kunert, R; Mayrhofer, P; Kreil, TR; Farcet, MR; Hoeltl, E; Wiedermann, U SARS-CoV-2-Specific Antibody (Ab) Levels and the Kinetic of Ab Decline Determine Ab Persistence Over 1 Year.

FRONT MED-LAUSANNE. 2022; 9, 822316 WoS PubMed FullText FullText_BOKU

PUBLIZIERTER Beitrag für wissenschaftliche Veranstaltung

** Garner-Spitzer, E; Wagner, A; Gudipati, V; Schoetta, AM; Orola-Taus, M; Tomosel, E; Kundi, M; Kunert, R; Mayrhofer, P; Huppa, JB; Novacek, G; Reinisch, W; Stockinger, H; Wiedermann, U Low antibody responses and early antibody waning after COVID vaccination is associated with failure of B memory cell formation in IBD (inflammatory bowel disease) patients.

EUR J IMMUNOL. 2022; 52: 83-84. WoS

2021

Originalbeitrag in Fachzeitschrift

** Laurent, E; Sieber, A; Salzer, B; Wachernig, A; Seigner, J; Lehner, M; Geyeregger, R; Kratzer, B; Jäger, U; Kunert, R; Pickl, WF; Traxlmayr, MW; Directed Evolution of Stabilized Monomeric CD19 for Monovalent CAR Interaction Studies and Monitoring of CAR-T Cell Patients..

ACS Synth Biol. 2021; 10(5):1184-1198 WoS PubMed

FullText FullText_BOKU

** Mayrhofer, P; Castan, A; Kunert, R Shake tube perfusion cell cultures are suitable tools for the prediction of limiting substrate, CSPR, bleeding strategy, growth and productivity behavior.

J CHEM TECHNOL BIOT. 2021; 96(10): 2930-2939. WoS FullText FullText_BOKU

** Mayrhofer, P; Hunjadi, M; Kunert, R Functional Trimeric SARS-CoV-2 Envelope Protein Expressed in Stable CHO Cells.

FRONT BIOENG BIOTECH. 2021; 9, 779359 WoS PubMed FullText FullText_BOKU

** Mayrhofer, P; Reinhart, D; Castan, A; Kunert, R Monitoring of heat- and light exposure of cell culture media by RAMAN spectroscopy: Towards an analytical tool for cell culture media quality control.

BIOCHEM ENG J. 2021; 166, 107845 WoS FullText FullText_BOKU

PUBLIZIERTER Beitrag für wissenschaftliche Veranstaltung

** Gudipati, V; Rydzek, J; Perez, ID; Goncalves, VDR; Scharf, L; Konigsberger, S; Lobner, E; Kunert, R; Einsele, H; Stockinger, H; Hudecek, M; Huppa, JB Inefficient CAR-proximal signaling blunts antigen sensitivity.

EUR J IMMUNOL. 2021; 51: 32-32. WoS

2020

Originalbeitrag in Fachzeitschrift

** Gudipati, V; Rydzek, J; Doel-Perez, I; Goncalves, VD; Scharf, L; Konigsberger, S; Lobner, E; Kunert, R; Einsele, H; Stockinger, H; Hudecek, M; Huppa, JB Inefficient CAR-proximal signaling blunts antigen sensitivity.

NAT IMMUNOL. 2020; 21(8): 848-+. WoS PubMed FullText FullText_BOKU

** Hennicke, J; Schwaigerlehner, L; Grunwald-Gruber, C; Bally, I; Ling, WL; Thielens, N; Reiser, JB; Kunert, R Transient pentameric IgM fulfill biological function-Effect of expression host and transfection on IgM properties.

PLOS ONE. 2020; 15(3), e0229992 WoS PubMed FullText FullText_BOKU

** Lobner, E; Wachernig, A; Gudipati, V; Mayrhofer, P; Salzer, B; Lehner, M; Huppa, JB; Kunert, R Getting CD19 Into Shape: Expression of Natively Folded "Difficult-to- Express" CD19 for Staining and Stimulation of CAR-T Cells.

FRONT BIOENG BIOTECH. 2020; 8, 49 WoS PubMed FullText FullText_BOKU

** Mayrhofer, P; Reinhart, D; Castan, A; Kunert, R; Rapid development of clone-specific, high-performing perfusion media from established feed supplements..

Biotechnol Prog. 2020; 36(2):e2933 WoS PubMed FullText FullText_BOKU

* Hennicke, J; Kunert, R; (2020): Analysis of Product Quality of Complex Polymeric IgM Produced by CHO Cells..

Methods Mol Biol. 2020; 2095:295-302 PubMed FullText FullText_BOKU

* Mayrhofer, P; Kunert, R; (2020): Screening of Media Supplements for High-Performance Perfusion Cultures by Design of Experiment..

Methods Mol Biol. 2020; 2095:27-39 PubMed FullText FullText_BOKU

Originalbeitrag in Sammelwerk

Mayrhofer,P; Kunert,R (2020): Screening of Media Supplements for High-Performance Perfusion Cultures by Design of Experiment.

In: Pörtner R. (eds), Animal Cell Biotechnology. Methods in Molecular Biology 2095, 27-39; Humana, New York; ISBN 978-1-0716-0191-4 FullText

2019

Originalbeitrag in Fachzeitschrift

** Hennicke, J; Reinhart, D; Altmann, F; Kunert, R Impact of temperature and pH on recombinant human IgM quality attributes and productivity.

NEW BIOTECHNOL. 2019; 50: 20-26. WoS PubMed FullText FullText_BOKU

** Reinhart, D; Damjanovic, L; Kaisermayer, C; Sommeregger, W; Gili, A; Gasselhuber, B; Castan, A; Mayrhofer, P; Grünwald-Gruber, C; Kunert, R; Bioprocessing of Recombinant CHO-K1, CHO-DG44, and CHO-S: CHO Expression Hosts Favor Either mAb Production or Biomass Synthesis..

Biotechnol J. 2019; 14(3):e1700686 WoS PubMed FullText FullText_BOKU

** Schwaigerlehner, L; Mayrhofer, P; Diem, M; Steinfellner, W; Fenech, E; Oostenbrink, C; Kunert, R; Germinality does not necessarily define mAb expression and thermal stability..

Appl Microbiol Biotechnol. 2019; 103(18):7505-7518 WoS PubMed FullText FullText_BOKU

** Trattnig, N; Mayrhofer, P; Kunert, R; Mach, L; Pantophlet, R; Kosma, P Comparative Antigenicity of Thiourea and Adipic Amide Linked Neoglycoconjugates Containing Modified Oligomannose Epitopes for the Carbohydrate-Specific anti-HIV Antibody 2G12.

BIOCONJUGATE CHEM. 2019; 30(1): 70-82. WoS PubMed FullText FullText_BOKU

* Mayrhofer, P; Kunert, R; (2019): Nomenclature of humanized mAbs: Early concepts, current challenges and future perspectives..

Hum Antibodies. 2019; 27(1):37-51 PubMed

FullText FullText_BOKU

PUBLIZIERTER Beitrag für wissenschaftliche Veranstaltung

** Reiser, JB; Hennicke, J; Bally, I; Chouquet, A; Ling, WL; Reinhart, D; Altmann, F; Kunert, R; Thielens, N EVALUATION OF C1q BINDING AND COMPLEMENT ACTIVATION OF NEW RECOMBINANT HUMAN IGMS AS QUALITY PRODUCTION ATTRIBUTES.
[17th European Meeting on Supercritical Fluids EMSF and 7th European Meeting on High Pressure Technology 2019, Madrid, Spain, 01.01.2019]

MOL IMMUNOL. 2019; 114: 426-426. WoS

J.-B. Reiser, J. Hennicke, I. Bally, A. Chouquet, W.-L. Ling, F. Altmann, R. Kunrt, N. Thielens (2019): Evaluation of C1p binding and complement activation of new recombinant human IgMs as quality attributes.. [Poster]
[17th European Meeting on Supercritical Fluids EMSF and 7th European Meeting on High Pressure Technology 2019, Madrid, Spain, 14.09.2019 - 17.09.2019]

2018

Originalbeitrag in Fachzeitschrift

** Albrecht, S; Kaisermayer, C; Reinhart, D; Ambrose, M; Kunert, R; Lindeberg, A; Bones, J Multiple reaction monitoring targeted LC-MS analysis of potential cell death marker proteins for increased bioprocess control.

ANAL BIOANAL CHEM. 2018; 410(13): 3197-3207. WoS PubMed FullText FullText_BOKU

** Reinhart, D; Damjanovic, L; Castan, A; Ernst, W; Kunert, R Differential gene expression of a feed-spiked super-producing CHO cell line.

J BIOTECHNOL. 2018; 285: 23-37. WoS PubMed FullText FullText_BOKU

** Schwaigerlehner, L; Pechlaner, M; Mayrhofer, P; Oostenbrink, C; Kunert, R; Lessons learned from merging wet lab experiments with molecular simulation to improve mAb humanization..

Protein Eng Des Sel. 2018; 31(7-8):257-265 WoS PubMed FullText FullText_BOKU

PUBLIZIERTER Beitrag für wissenschaftliche Veranstaltung

** Hennicke, J; Kunert, R Quality matters - Is IgM production influenced by external process conditions?.

NEW BIOTECHNOL. 2018; 44: S144-S144. WoS FullText FullText_BOKU

** Mundsperger, P; Gili, A; Sterovsky, T; Casanova, E; Kunert, R Understanding the heterologous expression of HIV-1 Env glycoproteins in CHO Cells.

NEW BIOTECHNOL. 2018; 44: S144-S144. WoS FullText FullText_BOKU

** Schwaigerlehner, L; Mayrhofer, P; Kunert, R Making the strange more familiar: Influence of germinality content on mAb expression potentials and thermal stability properties.

NEW BIOTECHNOL. 2018; 44: S66-S66. WoS FullText FullText_BOKU

2017

Originalbeitrag in Fachzeitschrift

** Battin, C; Hennig, A; Mayrhofer, P; Kunert, R; Zlabinger, GJ; Steinberger, P; Paster, W A human monocytic NF-kappa B fluorescent reporter cell line for detection of microbial contaminants in biological samples.

PLOS ONE. 2017; 12(5): WoS PubMed

FullText FullText_BOKU

** Hennicke, J; Lastin, AM; Reinhart, D; Grünwald-Gruber, C; Altmann, F; Kunert, R; Glycan profile of CHO derived IgM purified by highly efficient single step affinity chromatography..

Anal Biochem. 2017; 539:162-166 WoS PubMed FullText FullText_BOKU

* Mayrhofer, P; Kunert, R; (2017): Cloning of Single-Chain Antibody Variants by Overlap-Extension PCR for Evaluation of Antibody Expression in Transient Gene Expression..

Methods Mol Biol. 2017; 1603:57-69 PubMed FullText FullText_BOKU

PUBLIZIERTER Beitrag für wissenschaftliche Veranstaltung

Hennicke, J; Reinhart, D; Kunert R (2017): Analyses of product quality of complex polymeric IgM produced by CHO cells. [Poster]
[25th ESACT Meeting 2017, Lausanne, Switzerland, 14.05.2017 - 17.05.2017]

, BMC Proceedings, 12, 26-27

Schwaigerlehner, L; Mayrhofer, P; Pechlaner, M; Oostenbrink, C; Kunert, R (2017): Rational antibody humanization assisted by molecular dynamics simulations. [Poster]
[25th ESACT Meeting 2017, Lausanne, Switzerland, 14.05.2017 - 17.05.2017]

, BMC Proceedings, 12, 61-61

Trattnig, N; Pantophlet, R; Mayrhofer, P; Kunert, R, Kosma, P. (2017): Synthesis and vaccine potential of novel oligomannosides against HIV-1. [Poster]
[VII EFMC International Symposium on Advances in Synthetic and Medicinal Chemistry, Vienna, Austria, 27.08.2017 - 31.08.2017]

In: The European Federation of Medicinal Chemistry, Book of Abstracts, P312

Trattnig, N; Pantophlet, R; Mayrhofer, P; Kunert, R; Kosma, P. (2017): Synthesis and vaccine potential of novel oligomannosides against HIV-1. [Poster]
[19th European Carbohydrate Symposium 2017, Barcelona, Spain, 02.07.2017 - 06.07.2017]

In: Planas, A. (Ed.), Book of Abstracts, P 180

Trattnig, N; Pantophlet, R; Mayrhofer, P; Kunert, R; Kosma, P. (2017): Synthesis and vaccine potential of novel oligomannosides against HIV-1.
[14th Bratislava Symposium on Saccharides BSS 2017, Smolenice, Slovak Republic, 25.06.2017 - 30.06.2017]

In: Katrlík, J; Baráth, M. (Eds.), Proceedings of the 14th Bratislava symposium on saccharides, OP10; ISBN: 978-80-971156-3-0

2016

Originalbeitrag in Fachzeitschrift

** Kaisermayer, C; Reinhart, D; Gili, A; Chang, M; Aberg, PM; Castan, A; Kunert, R Biphasic cultivation strategy to avoid Epo-Fc aggregation and optimize protein expression.

J BIOTECHNOL. 2016; 227: 3-9. WoS PubMed FullText FullText_BOKU

** Kunert, R; Reinhart, D Advances in recombinant antibody manufacturing.

APPL MICROBIOL BIOT. 2016; 100(8): 3451-3461. WoS PubMed

FullText FullText_BOKU

** Margreitter, C; Mayrhofer, P; Kunert, R; Oostenbrink, C Antibody humanization by molecular dynamics simulations-in-silico guided selection of critical backmutations.

J MOL RECOGNIT. 2016; 29(6): 266-275. WoS PubMed FullText FullText_BOKU

** Sommeregger, W; Mayrhofer, P; Steinfellner, W; Reinhart, D; Henry, M; Clynes, M; Meleady, P; Kunert, R; Proteomic differences in recombinant CHO cells producing two similar antibody fragments..

Biotechnol Bioeng. 2016; 113(9):190-112 WoS PubMed

FullText FullText_BOKU

PUBLIZIERTER Beitrag für wissenschaftliche Veranstaltung

** Fazekas, J; Singer, J; Matz, M; Mader, A; Spillner, E; Kunert, R; Jensen-Jarolim, E AllergoOncology: generation of a canine anti-EGFR anticancer IgE.
[Meeting of the European Academy of Allergy and Clinical Immunology 2016, Vienna, Austria, 11.06.2016 - 15.06.2016]

; ISSN 0105-4538 WoS

Trattnig, N; Pantophlet, R; Mayrhofer, P; Kunert, R; Kosma, P. (2016): Synthesis of bacterial mimetics of HIV-1 gp120 glycans. [Poster]
[28th International Carbohydrate Symposium 2016, New Orleans, LA, USA, 17.07.2016 - 21.07.2016]

In: French, A (ED), Abstracts, http://ics-2016.org/index-03.html

2015

Originalbeitrag in Fachzeitschrift

** Chromikova, V; Mader, A; Hofbauer, S; Göbl, C; Madl, T; Gach, JS; Bauernfried, S; Furtmüller, PG; Forthal, DN; Mach, L; Obinger, C; Kunert, R; Introduction of germline residues improves the stability of anti-HIV mAb 2G12-IgM..

Biochim Biophys Acta. 2015; 1854(10 Pt A):1536-1544 WoS PubMed FullText FullText_BOKU

** Chromikova, V; Mader, A; Steinfellner, W; Kunert, R; Evaluating the bottlenecks of recombinant IgM production in mammalian cells..

Cytotechnology. 2015; 67(2):343-356 WoS PubMed

FullText FullText_BOKU

** Mayerhofer, B; Stöger, A; Pietzka, AT; Fernandez, HL; Prewein, B; Sorschag, S; Kunert, R; Allerberger, F; Ruppitsch, W; Improved protocol for rapid identification of certain spa types using high resolution melting curve analysis..

PLoS One. 2015; 10(3):e0116713 WoS PubMed

FullText FullText_BOKU

** Reinhart, D; Damjanovic, L; Kaisermayer, C; Kunert, R Benchmarking of commercially available CHO cell culture media for antibody production.

APPL MICROBIOL BIOT. 2015; 99(11): 4645-4657. WoS PubMed

FullText FullText_BOKU

** Reinhart, D; Kunert, R; Upstream and downstream processing of recombinant IgA..

Biotechnol Lett. 2015; 37(2):241-251 WoS PubMed FullText FullText_BOKU

** Zboray, K; Sommeregger, W; Bogner, E; Gili, A; Sterovsky, T; Fauland, K; Grabner, B; Stiedl, P; Moll, HP; Bauer, A; Kunert, R; Casanova, E; Heterologous protein production using euchromatin-containing expression vectors in mammalian cells..

Nucleic Acids Res. 2015; 43(16):e102 WoS PubMed FullText FullText_BOKU

Reinhart, D; Damjanovic, L; Sommeregger, W; Gili, A; Schafellner, S; Castan, A; Kaisermayer, C; Kunert, R (2015): Influence of cell culture media and feed supplements on cell metabolism and quality of IgG produced in CHO-K1, CHO-S, and CHO-DG44.

BMC Proceedings, 9, P36-P36; ISSN 1753-6561

PUBLIZIERTER Beitrag für wissenschaftliche Veranstaltung

Mayrhofer, P; Mader, A; Kratzer, B; Reinhart, D; Steinfellner, W; Sommeregger, W; Kunert, R (2015): Identification of bottlenecks in antibody expression using targeted gene integration. [Poster]
[24th ESACT 2015 - Cells, Culture, Patients, Products, Barcelona, Spain, 31.05.2015 - 03.06.2015]

, BMC Proceedings, 9, P7-P7

Puxbaum V., Landes N., Maccani A., Kunert R., Gasser B., Mattanovich D. (2015): Follow the protein: the secretory pathway of recombinant proteins in Pichia pastoris tracked via live cell microscopy .
[6th International Conference on Analysis of Microbial Cells at the Single Cell Level 2015, Retz, Austria, 19.07.2015 - 22.07.2015]

In: European Federation of Biotechnology, 6th International Conference on Analysis of Microbial Cells at the Single Cell Level

2014

Originalbeitrag in Fachzeitschrift

** Fliedl, L; Manhart, G; Kast, F; Katinger, H; Kunert, R; Grillari, J; Wieser, M; Grillari-Voglauer, R Novel human renal proximal tubular cell line for the production of complex proteins.

J BIOTECHNOL. 2014; 176: 29-39. WoS PubMed FullText FullText_BOKU

** Huber, G; Banki, Z; Kunert, R; Stoiber, H Novel Bifunctional Single-Chain Variable Antibody Fragments to Enhance Virolysis by Complement: Generation and Proof-of-Concept.

BIOMED RES INT. 2014; WoS PubMed

FullText FullText_BOKU

** Jadhav, V; Hackl, M; Klanert, G; Bort, JAH; Kunert, R; Grillari, J; Borth, N Stable overexpression of miR-17 enhances recombinant protein production of CHO cells.

J BIOTECHNOL. 2014; 175: 38-44. WoS PubMed

FullText FullText_BOKU

** Maccani, A; Hackl, M; Leitner, C; Steinfellner, W; Graf, AB; Tatto, NE; Karbiener, M; Scheideler, M; Grillari, J; Mattanovich, D; Kunert, R; Borth, N; Grabherr, R; Ernst, W Identification of microRNAs specific for high producer CHO cell lines using steady-state cultivation.

APPL MICROBIOL BIOT. 2014; 98(17): 7535-7548. WoS PubMed

FullText FullText_BOKU

** Maccani, A; Landes, N; Stadlmayr, G; Maresch, D; Leitner, C; Maurer, M; Gasser, B; Ernst, W; Kunert, R; Mattanovich, D Pichia pastoris secretes recombinant proteins less efficiently than Chinese hamster ovary cells but allows higher space-time yields for less complex proteins.

BIOTECHNOL J. 2014; 9(4): 526-537. WoS PubMed

FullText FullText_BOKU

** Mayrhofer, P; Kratzer, B; Sommeregger, W; Steinfellner, W; Reinhart, D; Mader, A; Turan, S; Qiao, J; Bode, J; Kunert, R; Accurate comparison of antibody expression levels by reproducible transgene targeting in engineered recombination-competent CHO cells..

Appl Microbiol Biotechnol. 2014; 98(23):9723-9733 WoS PubMed

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** Reinhart, D; Sommeregger, W; Debreczeny, M; Gludovacz, E; Kunert, R In search of expression bottlenecks in recombinant CHO cell lines-a case study..

Appl Microbiol Biotechnol. 2014; 98(13):5959-5965 WoS PubMed FullText FullText_BOKU

** Singer, J; Fazekas, J; Wang, W; Weichselbaumer, M; Matz, M; Mader, A; Steinfellner, W; Meitz, S; Mechtcheriakova, D; Sobanov, Y; Willmann, M; Stockner, T; Spillner, E; Kunert, R; Jensen-Jarolim, E Generation of a Canine Anti-EGFR (ErbB-1) Antibody for Passive Immunotherapy in Dog Cancer Patients.

MOL CANCER THER. 2014; 13(7): 1777-1790. WoS FullText FullText_BOKU

PUBLIZIERTER Beitrag für wissenschaftliche Veranstaltung

** Fazekas, J; Singer, J; Wang, W; Weichselbaumer, M; Matz, M; Mader, A; Steinfellner, W; Meitz, S; Mechtcheriakova, D; Sobanov, Y; Willmann, M; Stockner, T; Spillner, E; Kunert, R; Jensen-Jarolim, E Can225IgG, the first 'caninised' antibody against EGFR is highly effective in mediating tumor cell growth inhibition and phagocytosis in vitro.
[European-Academy-of-Allergy-and-Clinical-Immunology Congress 2014, Copenhagen, Denmark, 07.06.2014 - 11.06.2014]

ALLERGY. 2014; 69: 533-533. WoS

INT J MOL MED. 2014; 34: S128-S128. WoS

** Fliedl, L; Wieser, M; Manhart, G; Gerstl, MP; Kast, F; Khan, A; Kunert, R; Grillari, J; Grillari-Voglauer, R Novel human kidney epithelial cell line in pharmaceutical biotechnology.

NEW BIOTECHNOL. 2014; 31: S72-S72. WoS FullText FullText_BOKU

** Landes, N; Maccani, A; Leitner, C; Maurer, M; Graf, AB; Valli, M; Gruber, C; Modarres, G; Altmann, F; Gasser, B; Ernst, W; Kunert, R; Mattanovich, D Cross-species comparison of recombinant protein secretion in CHO cells and Pichia pastoris.

NEW BIOTECHNOL. 2014; 31: S4-S4. WoS FullText FullText_BOKU

** Mayrhofer, P; Mader, A; Kunert, R RMCE reference sites - A valuable tool for comparing antibody expression capabilities in CHO cells.

NEW BIOTECHNOL. 2014; 31: S186-S187. WoS FullText FullText_BOKU

** Singer, J; Fazekas, J; Wang, W; Weichselbaumer, M; Matz, M; Mader, A; Steinfellner, W; Meitz, S; Mechtcheriakova, D; Sobanov, Y; Stockner, T; Spillner, E; Kunert, R; Willmann, M; Thalhammer, J; Jensen-Jarolim, E IgE-based immunotherapy of cancer-A comparative oncology approach.

INT J MOL MED. 2014; 34: S127-S127. WoS

** Sommeregger, W; Gili, A; Zboray, K; Sterovsky, T; Casanova, E; Kunert, R Establishment of stable, high producing, recombinant CHO cell lines using Rosa26 Bacterial Artificial Chromosomes for transgene delivery.

NEW BIOTECHNOL. 2014; 31: S187-S187. WoS FullText FullText_BOKU

2013

Originalbeitrag in Fachzeitschrift

** Ladenstein, R; Weixler, S; Baykan, B; Bleeke, M; Kunert, R; Katinger, D; Pribill, I; Glander, P; Bauer, S; Pistoia, V; Michon, J; Garaventa, A; Lode, HN Ch14.18 antibody produced in CHO cells in relapsed or refractory Stage 4 neuroblastoma patients A SIOPEN phase 1 study.

MABS-AUSTIN. 2013; 5(5): 801-809. WoS FullText FullText_BOKU

** Mader, A; Prewein, B; Zboray, K; Casanova, E; Kunert, R; Exploration of BAC versus plasmid expression vectors in recombinant CHO cells..

Appl Microbiol Biotechnol. 2013; 97(9):4049-4054 WoS PubMed FullText FullText_BOKU

** Sommeregger, W; Prewein, B; Reinhart, D; Mader, A; Kunert, R; Transgene copy number comparison in recombinant mammalian cell lines: critical reflection of quantitative real-time PCR evaluation..

Cytotechnology. 2013; 65(5):811-818 WoS PubMed

FullText FullText_BOKU

Mader, A; Chromikova, V; Kunert, R (2013): Recombinant IgM expression in mammalian cells: A target protein challenging biotechnological production.

Advances in Bioscience and Biotechnology, 4, 38-43; ISSN 2156-8456 FullText

* Reinhart, D; Kaisermayer, C; Kunert, R (2013): Benchmarking of commercially available CHO cell culture media for antibody production.

BMC Proceedings, 7, P13-P13; ISSN 1753-6561 FullText

* Reinhart, D; Sommeregger, W; Debreczeny, M; Gludovacz, E; Kunert, R (2013): Characterization of recombinant IgA producing CHO cell lines by qPCR.

BMC Proceedings, 7, P114-P114; ISSN 1753-6561 FullText

PUBLIZIERTER Beitrag für wissenschaftliche Veranstaltung

** Fazekas, J; Singer, J; Wang, W; Weichselbaumer, M; Matz, M; Mader, A; Steinfellner, W; Meitz, S; Mechtcheriakova, D; Sobanov, Y; Stockner, T; Spillner, E; Kunert, R; Jensen-Jarolim, E Passive anti-EGFR immunotherapy in canine cancer patients - a comparative medicine study.
[World Allergy and Asthma Congress of the European-Academy-of-Allergy-and-Clinical-Immunology and World-Allergy-Organization, Milan, Italy, 22.06.2013 - 26.06.2013]

ALLERGY. 2013; 68: 590-590. WoS

Landes, N; Maccani, A; Leitner, C; Maurer, M; Gasser, B; Ernst, W; Kunert, R; Mattanovich, D. (2013): Cross-species comparison of recombinant protein secretion in CHO cells and Pichia pastoris. [Poster]
[7th Conference on Recombinant Protein Production RPP7 2013, Laupheim, Germany, 06.03.2013 - 08.03.2013]

In: European Federation of Biotechnology, RPP7-Abstract Book

Maccani, A., Tatto, N., Graf, A., Leitner, C., Mattanovich, D., Kunert, R., Ernst, W. (2013): Transcriptome study of high and low producing recombinant Chinese hamster ovary cell lines. [Poster]
[7th Conference on Recombinant Protein Production RPP7 2013, Laupheim, Germany, 06.03.2013 - 08.03.2013]

In: European Federation of Biotechnology, RPP7-Abstract Book

Sommeregger, W; Gili, A; Sterovsky, T; Casanova, E; Kunert, R (2013): Powerful expression in Chinese Hamster Ovary cells using bacterial artificial chromosomes: parameters influencing productivity. [Poster]
[23rd ESACT Meeting - Better Cells for Better Health, Lille, France, 23.06.2013 - 26.06.2013]

, BMC Proceedings, 7; ISBN: doi:10.1186/1753-656

2012

Originalbeitrag in Fachzeitschrift

** Huarte, N; Araujo, A; Arranz, R; Lorizate, M; Quendler, H; Kunert, R; Valpuesta, JM; Nieva, JL Recognition of Membrane-Bound Fusion-Peptide/MPER Complexes by the HIV-1 Neutralizing 2F5 Antibody: Implications for Anti-2F5 Immunogenicity.

PLOS ONE. 2012; 7(12): WoS FullText FullText_BOKU

** Jadhav, V; Hackl, M; Hernandez Bort, JA; Wieser, M; Harreither, E; Kunert, R; Borth, N; Grillari, J A screening method to assess biological effects of microRNA overexpression in Chinese hamster ovary cells..

Biotechnol Bioeng. 2012; 109(6):1376-1385 WoS PubMed FullText FullText_BOKU

** Mader, A; Kunert, R; Evaluation of the potency of the anti-idiotypic antibody Ab2/3H6 mimicking gp41 as an HIV-1 vaccine in a rabbit prime/boost study..

PLoS One. 2012; 7(6):e39063 WoS PubMed

FullText FullText_BOKU

** Reinhart, D; Weik, R; Kunert, R; Recombinant IgA production: single step affinity purification using camelid ligands and product characterization..

J Immunol Methods. 2012; 378(1-2):95-101 WoS PubMed

** Rodriguez-Carmona, E; Cano-Garrido, O; Dragosits, M; Maurer, M; Mader, A; Kunert, R; Mattanovich, D; Villaverde, A; Vazquez, F Recombinant Fab expression and secretion in Escherichia coli continuous culture at medium cell densities: Influence of temperature.

PROCESS BIOCHEM. 2012; 47(3): 446-452. WoS FullText FullText_BOKU

** Taschwer, M; Hackl, M; Hernández Bort, JA; Leitner, C; Kumar, N; Puc, U; Grass, J; Papst, M; Kunert, R; Altmann, F; Borth, N Growth, productivity and protein glycosylation in a CHO EpoFc producer cell line adapted to glutamine-free growth..

J Biotechnol. 2012; 157(2):295-303 WoS PubMed FullText FullText_BOKU

** Zeinzinger, J; Pietzka, AT; Stoger, A; Kornschober, C; Kunert, R; Allerberger, F; Mach, R; Ruppitsch, W One-Step Triplex High-Resolution Melting Analysis for Rapid Identification and Simultaneous Subtyping of Frequently Isolated Salmonella Serovars.

APPL ENVIRON MICROB. 2012; 78(9): 3352-3360. WoS PubMed

FullText FullText_BOKU

* Kunert, R; Vorauer-Uhl, K; (2012): Strategies for efficient transfection of CHO-cells with plasmid DNA..

Methods Mol Biol. 2012; 801:213-226 PubMed FullText FullText_BOKU

PUBLIZIERTER Beitrag für wissenschaftliche Veranstaltung

Mader, A; Kunert, R (2012): Human recombinant IgMs: a challenging molecule in mammalian cell expression. [Poster]
[15th European Congress on Biotechnology ECB15 2012 - Biocrossroads, Istanbul, Turkey, 23.09.2012 - 26.09.2012]

, New Biotechnology, 29, 1-242; ISSN 1871-6784

Originalbeitrag in Sammelwerk

Renate Kunert (2012): The Neutralizing Anti-HIV Antibody 2G12.

In: Paul Kosma, Sven Müller-Loennies, Anticarbohydrate Antibodies, 147-160; Springer-Verlag, Wien; ISBN 978-3-7091-0869-7

2011

Monographie

Renate Kunert, Karola Vorauer-Uhl (2011): Protein expression in mammalian cells: "Strategies for efficient transfection of CHO-cells with plasmid DNA".

, 14, Springer, New York; ISBN: 978-1-61779-351-6

Originalbeitrag in Fachzeitschrift

** de Ruiter, A; Mader, A; Kunert, R; Oostenbrink, C Molecular Simulations to Rationalize Humanized Ab2/3H6 Activity.

AUST J CHEM. 2011; 64(7): 900-909. WoS FullText FullText_BOKU

** Dragosits, M; Frascotti, G; Bernard-Granger, L; Vazquez, F; Giuliani, M; Baumann, K; Rodriguez-Carmona, E; Tokkanen, J; Parrilli, E; Wiebe, MG; Kunert, R; Maurer, M; Gasser, B; Sauer, M; Branduardi, P; Pakula, T; Saloheimo, M; Penttila, M; Ferrer, P; Tutino, ML; Villaverde, A; Porro, D; Mattanovich, D Influence of Growth Temperature on the Production of Antibody Fab Fragments in Different Microbes: A Host Comparative Analysis.

BIOTECHNOL PROGR. 2011; 27(1): 38-46. WoS PubMed FullText FullText_BOKU

** Hackl, M; Jakobi, T; Blom, J; Doppmeier, D; Brinkrolf, K; Szczepanowski, R; Bernhart, SH; Siederdissen, CH; Bort, JA; Wieser, M; Kunert, R; Jeffs, S; Hofacker, IL; Goesmann, A; Pühler, A; Borth, N; Grillari, J Next-generation sequencing of the Chinese hamster ovary microRNA transcriptome: Identification, annotation and profiling of microRNAs as targets for cellular engineering..

J Biotechnol. 2011; 153(1-2):62-75 WoS PubMed

FullText FullText_BOKU

** Loos, A; Van Droogenbroeck, B; Hillmer, S; Grass, J; Kunert, R; Cao, JY; Robinson, DG; Depicker, A; Steinkellner, H Production of monoclonal antibodies with a controlled N-glycosylation pattern in seeds of Arabidopsis thaliana.

PLANT BIOTECHNOL J. 2011; 9(2): 179-192. WoS PubMed FullText FullText_BOKU

** Loos, A; Van Droogenbroeck, B; Hillmer, S; Grass, J; Pabst, M; Castilho, A; Kunert, R; Liang, M; Arcalis, E; Robinson, DG; Depicker, A; Steinkellner, H Expression of antibody fragments with a controlled N-glycosylation pattern and induction of endoplasmic reticulum-derived vesicles in seeds of Arabidopsis..

Plant Physiol. 2011; 155(4):2036-2048 WoS PubMed

FullText FullText_BOKU

** Maeso, R; Huarte, N; Julien, JP; Kunert, R; Pai, EF; Nieva, JL Interaction of Anti-HIV Type 1 Antibody 2F5 with Phospholipid Bilayers and Its Relevance for the Mechanism of Virus Neutralization.

AIDS RES HUM RETROV. 2011; 27(8): 863-876. WoS FullText FullText_BOKU

* Kunert, R; Mader, A; (2011): Anti-idiotypic antibody Ab2/3H6 mimicking gp41: a potential HIV-1 vaccine?.

BMC Proc. 2011; 5 Suppl 8:P64 PubMed

FullText FullText_BOKU

* Reinhart, D; Weik, R; Kunert, R (2011): 3D6 and 4B3: Recombinant expression of two anti-gp41 antibodies as dimeric and secretory IgA.

BMC Proceedings, 5, P56-P56; ISSN 1753-6561 FullText

PUBLIZIERTER Beitrag für wissenschaftliche Veranstaltung

Castilho, A., Gattinger, P., Pabst, M., Grass, J., Kunert, R., Strasser, R., Altmann, F., Steinkellner, H (2011): Humanization of the plant N-glycosylation pathway for the production of therapeutically relevant proteins .
[21st International Symposium on Glycoconjugates GLYCO 21, 2011, Vienna, Austria, 21.08.2011 - 26.08.2011]

, Glycoconjugate Journal, 28, 240-240; ISSN 0282-0080

Renate Kunert (2011): Recombinant human IgMs: Purification, characterization and modification.
[The new ParadIgM 2011 - IgM from bench to clinic, Frankfurt am Main, Germany, 15.11.2011 - 16.11.2011]

In: Dechema Biotechnologie, Workshop: The new ParadIgM – IgM from bench to clinic

Renate Kunert Alexander Mader (2011): Anti-idiotypic antibody Ab2/3H6 mimicking gp41: a potential HIV-1 vaccine?. [Poster]
[22nd meeting of the European Society for Animal Cell Technology ESACT 2011, Vienna, Austria, 15.05.2011 - 18.05.2011]

, BMC Proceedings, 5; ISSN 1753-6561

2010

Originalbeitrag in Fachzeitschrift

** Apellaniz, B; García-Sáez, AJ; Huarte, N; Kunert, R; Vorauer-Uhl, K; Katinger, H; Schwille, P; Nieva, JL Confocal microscopy of giant vesicles supports the absence of HIV-1 neutralizing 2F5 antibody reactivity to plasma membrane phospholipids..

FEBS Lett. 2010; 584(8):1591-1596 WoS PubMed FullText FullText_BOKU

** Bohm-Hofstatter, H; Tschernutter, M; Kunert, R Comparison of hybridization methods and real-time PCR: their value in animal cell line characterization.

APPL MICROBIOL BIOTECHNOL. 2010; 87(2): 419-425. WoS PubMed FullText FullText_BOKU

** Castilho, A; Strasser, R; Stadlmann, J; Grass, J; Jez, J; Gattinger, P; Kunert, R; Quendler, H; Pabst, M; Leonard, R; Altmann, F; Steinkellner, H In Planta Protein Sialylation through Overexpression of the Respective Mammalian Pathway.

J BIOL CHEM. 2010; 285(21): 15923-15930. WoS PubMed

FullText FullText_BOKU

** Forthal, DN; Gach, JS; Landucci, G; Jez, J; Strasser, R; Kunert, R; Steinkellner, H Fc-Glycosylation Influences Fc gamma Receptor Binding and Cell-Mediated Anti-HIV Activity of Monoclonal Antibody 2G12.

J IMMUNOL. 2010; 185(11): 6876-6882. WoS PubMed FullText FullText_BOKU

** Gach, JS; Furtmüller, PG; Quendler, H; Messner, P; Wagner, R; Katinger, H; Kunert, R Proline is not uniquely capable of providing the pivot point for domain swapping in 2G12, a broadly neutralizing antibody against HIV-1..

J Biol Chem. 2010; 285(2):1122-1127 WoS PubMed

FullText FullText_BOKU

** Joseph, A; Zheng, JH; Chen, K; Dutta, M; Chen, CD; Stiegler, G; Kunert, R; Follenzi, A; Goldstein, H Inhibition of In Vivo HIV Infection in Humanized Mice by Gene Therapy of Human Hematopoietic Stem Cells with a Lentiviral Vector Encoding a Broadly Neutralizing Anti-HIV Antibody.

J VIROL. 2010; 84(13): 6645-6653. WoS PubMed

FullText FullText_BOKU

** Mader, A; Kunert, R; Humanization strategies for an anti-idiotypic antibody mimicking HIV-1 gp41..

Protein Eng Des Sel. 2010; 23(12):947-954 WoS PubMed FullText FullText_BOKU

** Strobach, S; Kunert, R; Stadlmann, J; Messner, P; Sevcsik, E; Lhota, G; Katinger, H; Vorauer-Uhl, K; Topological transformation of liposomes by a membrane-affecting domain of recombinant human erythropoietin..

J Liposome Res. 2010; 20(1):24-30 WoS PubMed

FullText FullText_BOKU

** Vorauer-Uhl, K; Wallner, J; Lhota, G; Katinger, H; Kunert, R IgM characterization directly performed in crude culture supernatants by a new simple electrophoretic method.

J IMMUNOL METHOD. 2010; 359(1-2): 21-27. WoS PubMed FullText FullText_BOKU

PUBLIZIERTER Beitrag für wissenschaftliche Veranstaltung

** Maeso, R; Kunert, R; Nieva, JL Membrane pore formation by the human immunodeficiency virus type-1 neutralizing anti-gp41 antibody 2F5.

CHEM PHYS LIPIDS. 2010; 163: S46-S46. WoS FullText FullText_BOKU

Renate Kunert, Alexander Mader, Hermann Katinger (2010): Humanization variants of an anti-idiotypic antibody. [Poster]
[Human Antibodies and Hybridomas 2010, Porto, Portugal, 14.04.2010 - 16.04.2010]

In: Mark C Glassy, Human antibodies

2009

Originalbeitrag in Fachzeitschrift

** Kunert, R; Steinfellner, W; Altmann, F; Wallner, J; Katinger, H; Vorauer-Uhl, K; CHO-recombinant human growth hormone as a protease sensitive reporter protein..

Appl Microbiol Biotechnol. 2009; 84(4):693-699 WoS PubMed FullText FullText_BOKU

** Pichler, J; Hesse, F; Wieser, M; Kunert, R; Galosy, SS; Mott, JE; Borth, N A study on the temperature dependency and time course of the cold capture antibody secretion assay..

J Biotechnol. 2009; 141(1-2):80-83 WoS PubMed FullText FullText_BOKU

** Reisinger, H; Steinfellner, W; Katinger, H; Kunert, R Serum-free transfection of CHO cells with chemically defined transfection systems and investigation of their potential for transient and stable transfection.

CYTOTECHNOLOGY. 2009; 60(1-3): 115-123. WoS PubMed

FullText FullText_BOKU

** Stadlmann, J; Weber, A; Pabst, M; Anderle, H; Kunert, R; Ehrlich, HJ; Peter Schwarz, H; Altmann, F; A close look at human IgG sialylation and subclass distribution after lectin fractionation..

Proteomics. 2009; 9(17):4143-4153 WoS PubMed FullText FullText_BOKU

** Strasser, R; Castilho, A; Stadlmann, J; Kunert, R; Quendler, H; Gattinger, P; Jez, J; Rademacher, T; Altmann, F; Mach, L; Steinkellner, H Improved virus neutralization by plant-produced anti-HIV antibodies with a homogeneous beta1,4-galactosylated N-glycan profile..

J Biol Chem. 2009; 284(31):20479-20485 WoS PubMed

FullText FullText_BOKU

PUBLIZIERTER Beitrag für wissenschaftliche Veranstaltung

** Binley, J; Wrin, T; Pantophlet, R; Phung, P; Crooks, ET; Lapedes, A; Taylor, N; Cavacini, L; Steigler, G; Kunert, R; Katinger, H; Petropoulos, C; Richman, D; Morris, L; Sutthent, R; Burton, DR Cross-clade neutralization analysis of plasmas from clade B, C and CRF01_AE HIV-infected donors.

RETROVIROLOGY. 2009; 6: WoS

Glössl, J., Strasser, R., Castilho, A., Kunert, R., Altmann, F., Mach, L., Steinkellner, H. (2009): Glyco-engineering in plants: production of monoclonal antibodies containing homogeneously β1,4-galactosylated human-type N-glycans..
[GLYCOBIOLOGY 2009, San Diego, CA, USA, 12.11.2009 - 15.11.2009]

, Glycoconj. Journal, 26, 827

2008

Originalbeitrag in Fachzeitschrift

** Bryson, S; Julien, JP; Isenman, DE; Kunert, R; Katinger, H; Pai, EF Crystal structure of the complex between the F(ab)' fragment of the cross-neutralizing anti-HIV-1 antibody 2F5 and the F(ab) fragment of its anti-idiotypic antibody 3H6..

J Mol Biol. 2008; 382(4):910-919 WoS PubMed FullText FullText_BOKU

** Gach, JS; Quendler, H; Ferko, B; Katinger, H; Kunert, R Expression, purification, and in vivo administration of a promising anti-idiotypic HIV-1 vaccine..

Mol Biotechnol. 2008; 39(2):119-125 WoS PubMed FullText FullText_BOKU

** Gach, JS; Quendler, H; Strobach, S; Katinger, H; Kunert, R Structural analysis and in vivo administration of an anti-idiotypic antibody against mAb 2F5..

Mol Immunol. 2008; 45(4):1027-1034 WoS PubMed FullText FullText_BOKU

** Huarte, N; Lorizate, M; Kunert, R; Nieva, JL Lipid modulation of membrane-bound epitope recognition and blocking by HIV-1 neutralizing antibodies..

FEBS Lett. 2008; 582(27):3798-3804 WoS PubMed FullText FullText_BOKU

** Huarte, N; Lorizate, M; Maeso, R; Kunert, R; Arranz, R; Valpuesta, JM; Nieva, JL The broadly neutralizing anti-human immunodeficiency virus type 1 4E10 monoclonal antibody is better adapted to membrane-bound epitope recognition and blocking than 2F5..

J Virol. 2008; 82(18):8986-8996 WoS PubMed

FullText FullText_BOKU

** Jin, C; Altmann, F; Strasser, R; Mach, L; Schähs, M; Kunert, R; Rademacher, T; Glössl, J; Steinkellner, H A plant-derived human monoclonal antibody induces an anti-carbohydrate immune response in rabbits..

Glycobiology. 2008; 18(3):235-241 WoS PubMed FullText FullText_BOKU

** Menendez, A; Calarese, DA; Stanfield, RL; Chow, KC; Scanlan, CN; Kunert, R; Katinger, H; Burton, DR; Wilson, IA; Scott, JK A peptide inhibitor of HIV-1 neutralizing antibody 2G12 is not a structural mimic of the natural carbohydrate epitope on gp120..

FASEB J. 2008; 22(5):1380-1392 WoS PubMed

FullText FullText_BOKU

** Rademacher, T; Sack, M; Arcalis, E; Stadlmann, J; Balzer, S; Altmann, F; Quendler, H; Stiegler, G; Kunert, R; Fischer, R; Stoger, E Recombinant antibody 2G12 produced in maize endosperm efficiently neutralizes HIV-1 and contains predominantly single-GlcNAc N-glycans..

Plant Biotechnol J. 2008; 6(2):189-201 WoS PubMed FullText FullText_BOKU

** Reisinger, H; Steinfellner, W; Stern, B; Katinger, H; Kunert, R The absence of effect of gene copy number and mRNA level on the amount of mAb secretion from mammalian cells..

Appl Microbiol Biotechnol. 2008; 81(4):701-710 WoS PubMed FullText FullText_BOKU

** Stadlmann, J; Pabst, M; Kolarich, D; Kunert, R; Altmann, F; Analysis of immunoglobulin glycosylation by LC-ESI-MS of glycopeptides and oligosaccharides..

Proteomics. 2008; 8(14):2858-2871 WoS PubMed FullText FullText_BOKU

* Renate Kunert, Johannes Gach, Hermann Katinger (2008): Expression of a Fab Fragment in CHO and Pichia pastoris. A Comparative Case Study.

BioProcess International, June SUPPLEMENT, 34-40; ISSN 1542-6319

* Trummer, E; Ernst, W; Hesse, F; Schriebl, K; Lattenmayer, C; Kunert, R; Vorauer-Uhl, K; Katinger, H; Müller, D (2008): Transcriptional profiling of phenotypically different Epo-Fc expressing CHO clones by cross-species microarray analysis..

Biotechnol J. 2008; 3(7):924-937 PubMed FullText FullText_BOKU

PUBLIZIERTER Beitrag für wissenschaftliche Veranstaltung

Renate Kunert, H. Reisinger, W. Steinfellner, B. Stern, H. Katinger (2008): Influence of different genetic parameters and regulatory sequences on recombinant expression of a monoclonal antibody. [Poster]
[Human Antibodies and Hybridomas 2008, New York City, NY, USA, 12.11.2008 - 14.11.2008]

, Human Antibodies, 17, 1,2, 2008, 33-33; ISSN 1093-2607

2007

Originalbeitrag in Fachzeitschrift

** Gach, JS; Maurer, M; Hahn, R; Gasser, B; Mattanovich, D; Katinger, H; Kunert, R High level expression of a promising anti-idiotypic antibody fragment vaccine against HIV-1 in Pichia pastoris..

J Biotechnol. 2007; 128(4):735-746 WoS PubMed FullText FullText_BOKU

** Gach, JS; Quendler, H; Weik, R; Katinger, H; Kunert, R Partial humanization and characterization of an anti-idiotypic antibody against monoclonal antibody 2F5, a potential HIV vaccine?.

AIDS Res Hum Retroviruses. 2007; 23(11):1405-1415 WoS PubMed FullText FullText_BOKU

** Hinterkörner, G; Brugger, G; Müller, D; Hesse, F; Kunert, R; Katinger, H; Borth, N Improvement of the energy metabolism of recombinant CHO cells by cell sorting for reduced mitochondrial membrane potential..

J Biotechnol. 2007; 129(4):651-657 WoS PubMed FullText FullText_BOKU

** Lattenmayer, C; Loeschel, M; Schriebl, K; Steinfellner, W; Sterovsky, T; Trummer, E; Vorauer-Uhl, K; Müller, D; Katinger, H; Kunert, R Protein-free transfection of CHO host cells with an IgG-fusion protein: selection and characterization of stable high producers and comparison to conventionally transfected clones..

Biotechnol Bioeng. 2007; 96(6):1118-1126 WoS PubMed FullText FullText_BOKU

** Lattenmayer C, Trummer E, Schriebl K, Vorauer-Uhl K, Müller D, Katinger H, Kunert R Characterization of Recombinant CHO Cell Lines by Investigation of Protein Productivities and Genetic Parameters..

J BIOTECHNOL, 128 (4), 716-725; ISSN 0168-1656 WoS PubMed FullText FullText_BOKU

** Reisinger, H; Sevcsik, E; Vorauer-Uhl, K; Lohner, K; Katinger, H; Kunert, R Serum-free transfection of CHO-cells with tailor-made unilamellar vesicles..

Cytotechnology. 2007; 54(3):157-168 WoS PubMed

FullText FullText_BOKU

** Sack, M; Paetz, A; Kunert, R; Bomble, M; Hesse, F; Stiegler, G; Fischer, R; Katinger, H; Stoeger, E; Rademacher, T Functional analysis of the broadly neutralizing human anti-HIV-1 antibody 2F5 produced in transgenic BY-2 suspension cultures..

FASEB J. 2007; 21(8):1655-1664 WoS PubMed FullText FullText_BOKU

** Schähs, M; Strasser, R; Stadlmann, J; Kunert, R; Rademacher, T; Steinkellner, H Production of a monoclonal antibody in plants with a humanized N-glycosylation pattern..

Plant Biotechnol J. 2007; 5(5):657-663 WoS PubMed FullText FullText_BOKU

** Schriebl, K; Trummer, E; Weik, R; Lattenmayer, C; Müller, D; Kunert, R; Katinger, H; Vorauer-Uhl, K Applicability of different fluorescent dyes for isoform quantification on linear IPG gels..

Electrophoresis. 2007; 28(12):2100-2107 WoS PubMed FullText FullText_BOKU

** Vcelar, B; Stiegler, G; Wolf, HM; Muntean, W; Leschnik, B; Mehandru, S; Markowitz, M; Armbruster, C; Kunert, R; Eibl, MM; Katinger, H; Reassessment of autoreactivity of the broadly neutralizing HIV antibodies 4E10 and 2F5 and retrospective analysis of clinical safety data..

AIDS. 2007; 21(16):2161-2170 WoS PubMed FullText FullText_BOKU

Originalbeitrag in Sammelwerk

Gach, J., Steinfellner, W., Löschel, M., Hahn, R., Quendler, H., Katinger, H., Kunert, R. (2007): Characterization of an anti-idiotypic antibody blocking the capacity of the HIV-1 specific nMAb 2F5.

In: T. Noll, Animal Cell Technologies; Springer

2006

Originalbeitrag in Fachzeitschrift

** Gasser, B; Maurer, M; Gach, J; Kunert, R; Mattanovich, D; Engineering of Pichia pastoris for improved production of antibody fragments..

Biotechnol Bioeng. 2006; 94(2):353-361 WoS PubMed FullText FullText_BOKU

** Kunert, R; Gach, JS; Vorauer-Uhl, K; Engel, E; Katinger, H; Validated method for quantification of genetically modified organisms in samples of maize flour..

J Agric Food Chem. 2006; 54(3):678-681 WoS PubMed FullText FullText_BOKU

** Lattenmayer, C; Loeschel, M; Steinfellner, W; Trummer, E; Mueller, D; Schriebl, K; Vorauer-Uhl, K; Katinger, H; Kunert, R Identification of transgene integration loci of different highly expressing recombinant CHO cell lines by FISH..

Cytotechnology. 2006; 51(3):171-182 WoS PubMed

FullText FullText_BOKU

** Lorizate, M; Cruz, A; Huarte, N; Kunert, R; Pérez-Gil, J; Nieva, JL Recognition and blocking of HIV-1 gp41 pre-transmembrane sequence by monoclonal 4E10 antibody in a Raft-like membrane environment..

J Biol Chem. 2006; 281(51):39598-39606 WoS PubMed FullText FullText_BOKU

** Sánchez-Martínez, S; Lorizate, M; Hermann, K; Kunert, R; Basañez, G; Nieva, JL Specific phospholipid recognition by human immunodeficiency virus type-1 neutralizing anti-gp41 2F5 antibody..

FEBS Lett. 2006; 580(9):2395-2399 WoS PubMed FullText FullText_BOKU

** Sánchez-Martínez, S; Lorizate, M; Katinger, H; Kunert, R; Nieva, JL Membrane association and epitope recognition by HIV-1 neutralizing anti-gp41 2F5 and 4E10 antibodies..

AIDS Res Hum Retroviruses. 2006; 22(10):998-1006 WoS PubMed FullText FullText_BOKU

** Schriebl, K; Trummer, E; Lattenmayer, C; Weik, R; Kunert, R; Müller, D; Katinger, H; Vorauer-Uhl, K Biochemical characterization of rhEpo-Fc fusion protein expressed in CHO cells..

Protein Expr Purif. 2006; 49(2):265-275 WoS PubMed FullText FullText_BOKU

** Schriebl, K; Trummer, E; Weik, R; Müller, D; Kunert, R; Lattenmayer, C; Katinger, H; Vorauer-Uhl, K A novel strategy for quantitative isoform detection directly performed from culture supernatant..

J Pharm Biomed Anal. 2006; 42(3):322-327 WoS PubMed FullText FullText_BOKU

** Trummer, E; Fauland, K; Seidinger, S; Schriebl, K; Lattenmayer, C; Kunert, R; Vorauer-Uhl, K; Weik, R; Borth, N; Katinger, H; Müller, D Process parameter shifting: Part I. Effect of DOT, pH, and temperature on the performance of Epo-Fc expressing CHO cells cultivated in controlled batch bioreactors..

Biotechnol Bioeng. 2006; 94(6):1033-1044 WoS PubMed FullText FullText_BOKU

** Trummer, E; Fauland, K; Seidinger, S; Schriebl, K; Lattenmayer, C; Kunert, R; Vorauer-Uhl, K; Weik, R; Borth, N; Katinger, H; Müller, D Process parameter shifting: Part II. Biphasic cultivation-A tool for enhancing the volumetric productivity of batch processes using Epo-Fc expressing CHO cells..

Biotechnol Bioeng. 2006; 94(6):1045-1052 WoS PubMed FullText FullText_BOKU

PUBLIZIERTER Beitrag für wissenschaftliche Veranstaltung

Borth N., Brugger G., Hinterkörner G., Ernst W., Müller D., Hesse F., Kunert R., Katinger H. (2006): Cell Line Development by Fluorescence Activated Cell Sorting.
[Engineering Foundation Cell Culture Engineering X, Whistler, BC, Canada, 01.04.2006]

In: Engineering Foundation: Engineering Foundation Cell Culture Engineering X, April 2006, Whistler, Canada

Gach, J., Maurer, M., Quendler, H., Gasser, B., Löschel, M., Mattanovich, M., Katinger, H., Kunert, R. (2006): High Level Expression of a Humanised Ab2/3H6 Fab in Pichia Pastoris..
[Recombinant Antibodies, Zürich, Switzerland, 27.06.2005 - 29.06.2005]

In: Prof Dario Neri: Recombinant Antibodies, 27-29.06.2006, Zürich, Switzerland

Kunert, R., Gach, J., Preis, S., Löschel M., Weik, R., Ferko, B., Stiegler, G., Gasser, B., Mattanivich, D., Katinger, H. (2006): In vitro and in vivo characterization of an antiidiotypic antibody variants directed against the HIV-neutralizing mAb 2F5.
[Human Antibodies and Hybridomas 2006, Unknown, Jamaica, 10.05.2006 - 12.05.2006]

In: Mark C. Glassy: Human Antibodies and Hybridomas, 10. - 12.5.2006, Jamaica; Human Antibodies, 15 (1,2), 30-31; IOS - Press, Amsterdam Washington, DC Tokyo; ISSN ISSN 1093-2607

Strohbach,St., Wagner,A., Kunert,R., Katinger,H., Vorauer-Uhl, K. (2006): Encapsulation efficiency of lipid nano-vesicles for recombinant human Erythropoietin as a model protein.
[ILS 2006 Annual Meeting, London, UK, 09.12.2006 - 12.12.2006]

, International Liposome Society, 1, 53-53

Originalbeitrag in Sammelwerk

In: Mark C. Glassy, Human Antibodies and Hybridomas; IOS - Press, Amsterdam Washington, DC Tokyo

Skriptum

Borth, N., Gasser, B., Kunert, R., Mattanovich, D., Mattanovich, J., Prenner, C., Reinprecht, B., Voglauer, R., Vorauer-Uhl, K. (2006): Skriptum: Allgemeine Mikrobiologie Übungen.

Borth, N., Gasser, B., Kunert, R., Mattanovich, D., Mattanovich, J., Prenner, C., Reinprecht, B., Voglauer, R., Vorauer-Uhl, K. (2006): Arbeitsprotokolle: Einführung in das Mikrobiologische Arbeiten und Allgemeine Mikrobiologie Übungen.

2005

Originalbeitrag in Fachzeitschrift

** Böhm, E; Grillari, J; Voglauer, R; Gross, S; Ernst, W; Ferko, B; Kunert, R; Katinger, H; Borth, N Establishment of a strategy for the rapid generation of a monoclonal antibody against the human protein SNEV (hNMP200) by flow-cytometric cell sorting..

J Immunol Methods. 2005; 307(1-2):13-23 WoS PubMed FullText FullText_BOKU

** Borth, N; Mattanovich, D; Kunert, R; Katinger, H Effect of increased expression of protein disulfide isomerase and heavy chain binding protein on antibody secretion in a recombinant CHO cell line..

Biotechnol Prog. 2005; 21(1):106-111 WoS PubMed FullText FullText_BOKU

** Cardoso, RM; Zwick, MB; Stanfield, RL; Kunert, R; Binley, JM; Katinger, H; Burton, DR; Wilson, IA Broadly neutralizing anti-HIV antibody 4E10 recognizes a helical conformation of a highly conserved fusion-associated motif in gp41..

Immunity. 2005; 22(2):163-173 WoS PubMed FullText FullText_BOKU

** Haynes, BF; Fleming, J; St Clair, EW; Katinger, H; Stiegler, G; Kunert, R; Robinson, J; Scearce, RM; Plonk, K; Staats, HF; Ortel, TL; Liao, HX; Alam, SM Cardiolipin polyspecific autoreactivity in two broadly neutralizing HIV-1 antibodies..

Science. 2005; 308(5730):1906-1908 WoS PubMed FullText FullText_BOKU

** Nakowitsch, S; Quendler, H; Fekete, H; Kunert, R; Katinger, H; Stiegler, G HIV-1 mutants escaping neutralization by the human antibodies 2F5, 2G12, and 4E10: in vitro experiments versus clinical studies..

AIDS. 2005; 19(17):1957-1966 WoS PubMed FullText FullText_BOKU

** Zeng, Y; Fest, S; Kunert, R; Katinger, H; Pistoia, V; Michon, J; Lewis, G; Ladenstein, R; Lode, HN Anti-neuroblastoma effect of ch14.18 antibody produced in CHO cells is mediated by NK-cells in mice..

Mol Immunol. 2005; 42(11):1311-1319 WoS PubMed FullText FullText_BOKU

** Zwick, MB; Jensen, R; Church, S; Wang, M; Stiegler, G; Kunert, R; Katinger, H; Burton, DR Anti-human immunodeficiency virus type 1 (HIV-1) antibodies 2F5 and 4E10 require surprisingly few crucial residues in the membrane-proximal external region of glycoprotein gp41 to neutralize HIV-1..

J Virol. 2005; 79(2):1252-1261 WoS PubMed

FullText FullText_BOKU

PUBLIZIERTER Beitrag für wissenschaftliche Veranstaltung

Borth N., Böhm E., Grillari J., Löscher M., Gross S., Voglauer R., Ferko B., Kunert R., Katinger H. (2005): From gene to monoclonal antibody: efficient screening by cell sorting.
[Animal Cell Technology meets Genomics, Granada, Spain, 11.05.2003 - 15.05.2003]

In: Francesc Gòdia Casablancas (Ed.): Animal Cell Technology meets Genomics, May 11 - 15, 2003, Granada, Spain; Proceedings of the ESACT Meeting, 501-504, Granada

Christine Lattenmayer, Martina Löschel, Evelyn Trummer, Karola Vorauer-Uhl, Hermann Katinger, Renate Kunert (2005): Protein free transfection of CHO host cells with and IgG-fusion protein – selection and characterisation of stable high producers.
[60 Year Anniversary, Institute of Applied Microbiology IAM 2005, Vienna, Austria, 28.09.2005 - 29.09.2005]