** Grandits, M; Grunwald-Gruber, C; Gastine, S; Standing, JF; Reljic, R; Teh, AYH; Ma, JKC Improving the efficacy of plant-made anti-HIV monoclonal antibodies for clinical use.
** Braun, ML; Tomek, MB; Gruenwald-Gruber, C; Nguyen, PQ; Bloch, S; Potempa, JS; Andrukhov, O; Schaeffer, C Shut-Down of Type IX Protein Secretion Alters the Host Immune Response to Tannerella forsythia and Porphyromonas gingivalis.
** Geisslitz, S; Islam, S; Buck, L; Grunwald-Gruber, C; Sestili, F; Camerlengo, F; Masci, S; D'Amico, S Absolute and relative quantitation of amylase/trypsin-inhibitors by LC-MS/MS from wheat lines obtained by CRISPR-Cas9 and RNAi.
** Goritzer, K; Grandits, M; Grunwald-Gruber, C; Figl, R; Mercx, S; Navarre, C; Ma, JKC; Teh, AYH Engineering the N-glycosylation pathway of Nicotiana tabacum for molecular pharming using CRISPR/Cas9.
** Klausberger, M; Kienzl, NF; Stadlmayr, G; Grünwald-Gruber, C; Laurent, E; Stadlbauer, K; Stracke, F; Vierlinger, K; Hofner, M; Manhart, G; Gerner, W; Grebien, F; Weinhäusel, A; Mach, L; Wozniak-Knopp, G; Designed SARS-CoV-2 receptor binding domain variants form stable monomers..
** Koenig-Beihammer, J; Vavra, U; Shin, YJ; Veit, C; Gruenwald-Gruber, C; Gillitschka, Y; Huber, J; Hofner, M; Vierlinger, K; Mitteregger, D; Weinhaeusel, A; Strasser, R In Planta Production of the Receptor-Binding Domain From SARS-CoV-2 With Human Blood Group A Glycan Structures.
** Tir, N; Heistinger, L; Grunwald-Gruber, C; Jakob, LA; Dickgiesser, S; Rasche, N; Mattanovich, D From strain engineering to process development: monoclonal antibody production with an unnatural amino acid in Pichia pastoris.
** Uetz, P; Melnik, S; Grunwald-Gruber, C; Strasser, R; Stoger, E CRISPR/Cas9-mediated knockout of a prolyl-4-hydroxylase subfamily in Nicotiana benthamiana using DsRed2 for plant selection.
BIOTECHNOL J. 2022; 17(7), 2100698 WoS PubMed FullText FullText_BOKU** Atanasova, L; Moreno-Ruiz, D; Grünwald-Gruber, C; Hell, V; Zeilinger, S; The GPI-Anchored GH76 Protein Dfg5 Affects Hyphal Morphology and Osmoregulation in the Mycoparasite .
** Capraz, T; Kienzl, NF; Laurent, E; Perthold, JW; Föderl-Höbenreich, E; Grünwald-Gruber, C; Maresch, D; Monteil, V; Niederhöfer, J; Wirnsberger, G; Mirazimi, A; Zatloukal, K; Mach, L; Penninger, JM; Oostenbrink, C; Stadlmann, J; Structure-guided glyco-engineering of ACE2 for improved potency as soluble SARS-CoV-2 decoy receptor..
** Castilho, A; Schwestka, J; Kienzl, NF; Vavra, U; Grünwald-Gruber, C; Izadi, S; Hiremath, C; Niederhöfer, J; Laurent, E; Monteil, V; Mirazimi, A; Wirnsberger, G; Stadlmann, J; Stöger, E; Mach, L; Strasser, R; Generation of enzymatically competent SARS-CoV-2 decoy receptor ACE2-Fc in glycoengineered Nicotiana benthamiana..
** De Vos, J; Pereira Aguilar, P; Köppl, C; Fischer, A; Grünwald-Gruber, C; Dürkop, M; Klausberger, M; Mairhofer, J; Striedner, G; Cserjan-Puschmann, M; Jungbauer, A; Lingg, N; Production of full-length SARS-CoV-2 nucleocapsid protein from Escherichia coli optimized by native hydrophobic interaction chromatography hyphenated to multi-angle light scattering detection..
** Gattinger, P; Izadi, S; Grunwald-Gruber, C; Kallolimath, S; Castilho, A The Instability of Dimeric Fc-Fusions Expressed in Plants Can Be Solved by Monomeric Fc Technology.
** Helm, J; Grunwald-Gruber, C; Thader, A; Urteil, J; Fuhrer, J; Stenitzer, D; Maresch, D; Neumann, L; Pabst, M; Altmann, F Bisecting Lewis X in Hybrid-Type N-Glycans of Human Brain Revealed by Deep Structural Glycomics.
ANAL CHEM. 2021; 93(45): 15175-15182. WoS PubMed FullText FullText_BOKU** Hoffmann, D; Mereiter, S; Oh, YJ; Monteil, V; Elder, E; Zhu, R; Canena, D; Hain, L; Laurent, E; Grunwald-Gruber, C; Klausberger, M; Jonsson, G; Kellner, MJ; Novatchkova, M; Ticevic, M; Chabloz, A; Wirnsberger, G; Hagelkruys, A; Altmann, F; Mach, L; Stadlmann, J; Oostenbrink, C; Mirazimi, A; Hinterdorfer, P; Penninger, JM Identification of lectin receptors for conserved SARS-CoV-2 glycosylation sites.
EMBO J. 2021; 40(19), e108375 WoS PubMed FullText FullText_BOKU** Klausberger, M; Duerkop, M; Haslacher, H; Wozniak-Knopp, G; Cserjan-Puschmann, M; Perkmann, T; Lingg, N; Aguilar, PP; Laurent, E; De Vos, J; Hofner, M; Holzer, B; Stadler, M; Manhart, G; Vierlinger, K; Egger, M; Milchram, L; Gludovacz, E; Marx, N; Köppl, C; Tauer, C; Beck, J; Maresch, D; Grünwald-Gruber, C; Strobl, F; Satzer, P; Stadlmayr, G; Vavra, U; Huber, J; Wahrmann, M; Eskandary, F; Breyer, MK; Sieghart, D; Quehenberger, P; Leitner, G; Strassl, R; Egger, AE; Irsara, C; Griesmacher, A; Hoermann, G; Weiss, G; Bellmann-Weiler, R; Loeffler-Ragg, J; Borth, N; Strasser, R; Jungbauer, A; Hahn, R; Mairhofer, J; Hartmann, B; Binder, NB; Striedner, G; Mach, L; Weinhäusel, A; Dieplinger, B; Grebien, F; Gerner, W; Binder, CJ; Grabherr, R; A comprehensive antigen production and characterisation study for easy-to-implement, specific and quantitative SARS-CoV-2 serotests..
** Moore, CM; Grandits, M; Grunwald-Gruber, C; Altmann, F; Kotouckova, M; Teh, AYH; Ma, JKC Characterisation of a highly potent and near pan-neutralising anti-HIV monoclonal antibody expressed in tobacco plants.
** Omidvar, R; Vosseler, N; Abbas, A; Gutmann, B; Grunwald-Gruber, C; Altmann, F; Siddique, S; Bohlmann, H Analysis of a gene family for PDF-like peptides from Arabidopsis.
** Radoman, B; Grünwald-Gruber, C; Schmelzer, B; Zavec, D; Gasser, B; Altmann, F; Mattanovich, D; The Degree and Length of O-Glycosylation of Recombinant Proteins Produced in Pichia pastoris Depends on the Nature of the Protein and the Process Type..
** Shin, YJ; Konig-Beihammer, J; Vavra, U; Schwestka, J; Kienzl, NF; Klausberger, M; Laurent, E; Grunwald-Gruber, C; Vierlinger, K; Hofner, M; Margolin, E; Weinhausel, A; Stoger, E; Mach, L; Strasser, R N-Glycosylation of the SARS-CoV-2 Receptor Binding Domain Is Important for Functional Expression in Plants.
** Teh, AYH; Cavacini, L; Hu, Y; Kumru, OS; Xiong, J; Bolick, DT; Joshi, SB; Grunwald-Gruber, C; Altmann, F; Klempner, M; Guerrant, RL; Volkin, DB; Wang, Y; Ma, JKC Investigation of a monoclonal antibody against enterotoxigenic Escherichia coli, expressed as secretory IgA1 and IgA2 in plants.
** Tomek, MB; Janesch, B; Braun, ML; Taschner, M; Figl, R; Gruenwald-Gruber, C; Coyne, MJ; Blaukopf, M; Altmann, F; Kosma, P; Kaehlig, H; Comstock, LE; Schaeffer, C A Combination of Structural, Genetic, Phenotypic and Enzymatic Analyses Reveals the Importance of a Predicted Fucosyltransferase to Protein O-Glycosylation in the Bacteroidetes.
** Fraberger, V; Ladurner, M; Nemec, A; Grunwald-Gruber, C; Call, LM; Hochegger, R; Domig, KJ; D"Amico, S; Insights into the Potential of Sourdough-Related Lactic Acid Bacteria to Degrade Proteins in Wheat..
** Hennicke, J; Schwaigerlehner, L; Grunwald-Gruber, C; Bally, I; Ling, WL; Thielens, N; Reiser, JB; Kunert, R Transient pentameric IgM fulfill biological function-Effect of expression host and transfection on IgM properties.
** Kallolimath, S; Hackl, T; Gahn, R; Grunwald-Gruber, C; Zich, W; Kogelmann, B; Lux, A; Nimmerjahn, F; Steinkellner, H Expression Profiling and Glycan Engineering of IgG Subclass 1-4 inNicotiana benthamiana.
** Kittur, FS; Hung, CY; Zhu, CS; Shajahan, A; Azadi, P; Thomas, MD; Pearce, JL; Gruber, C; Kallolimath, S; Xie, JH Glycoengineering tobacco plants to stably express recombinant human erythropoietin with different N-glycan profiles.
INT J BIOL MACROMOL. 2020; 157: 158-169. WoS PubMed FullText FullText_BOKU** Kriechbaum, R; Ziaee, E; Grunwald-Gruber, C; Buscaill, P; van der Hoorn, RAL; Castilho, A BGAL1 depletion boosts the level of beta-galactosylation of N- and O-glycans in N. benthamiana.
** Valli, M; Grillitsch, K; Grünwald-Gruber, C; Tatto, NE; Hrobath, B; Klug, L; Ivashov, V; Hauzmayer, S; Koller, M; Tir, N; Leisch, F; Gasser, B; Graf, AB; Altmann, F; Daum, G; Mattanovich, D; A subcellular proteome atlas of the yeast Komagataella phaffii..
** Nika, L; Cuadrado-Castano, S; Arunkumar, GA; Grunwald-Gruber, C; McMahon, M; Koczka, K; Garcia-Sastre, A; Krammer, F; Grabherr, R A HER2-Displaying Virus-Like Particle Vaccine Protects from Challenge with Mammary Carcinoma Cells in a Mouse Model.
** Olagnon, C; Monjaras Feria, J; Grünwald-Gruber, C; Blaukopf, M; Valvano, MA; Kosma, P; Synthetic Phosphodiester-Linked 4-Amino-4-deoxy-l-arabinose Derivatives Demonstrate that ArnT is an Inverting Aminoarabinosyl Transferase..
** Reinhart, D; Damjanovic, L; Kaisermayer, C; Sommeregger, W; Gili, A; Gasselhuber, B; Castan, A; Mayrhofer, P; Grünwald-Gruber, C; Kunert, R; Bioprocessing of Recombinant CHO-K1, CHO-DG44, and CHO-S: CHO Expression Hosts Favor Either mAb Production or Biomass Synthesis..
** Schoberer, J; Liebminger, E; Vavra, U; Veit, C; Griinwald-Gruber, C; Altmann, F; Botchway, SW; Strasser, R The Golgi Localization of GnTI Requires a Polar Amino Acid Residue within Its Transmembrane Domain.
PLANT PHYSIOL. 2019; 180(2): 859-873. WoS PubMed FullText FullText_BOKU* Grünwald-Gruber, C; Altmann, F; (2019): LC-MS Analysis of (Glyco-)Proteins of Pichia pastoris..
Methods Mol Biol. 2019; 1923:351-360 PubMed FullText FullText_BOKU
Braun*, M., B. Janesch, M. B. Tomek, D. Maresch, C. Grünwald-Gruber, M. Blaukopf, P. Kosma, F. Altmann, C. Schäffer
(2019): A conserved glycosyltransferase from the general protein O-glycosylation pathway of Bacteroidetes.
[Soc. for Glycobiology Annual Meeting, Phoenix, AR, USA, 02.11.2019 - 05.11.2019]
Grünwald-Gruber, C; Olagnon, C; Julia Monjaras, F; Kosma, P; Altmann F
(2019): Analysis of bacterial arabinosyl transferase reaction products of Kdo2-lipid A by LC-ESI-MS.
[APMRS 2019, Salzburg, Austria, 18.09.2019 - 20.09.2019]
Olagnon, C; Feras, JM; Grünwald-Gruber, C; Altmann, F; Kerner, L; Valvano, MA, Kosma, P.
(2019): Investigation of 4-amino-4-deoxy-L-arabinose transferases from Gram-negative bacteria involved in antibiotic resistance.
[Eurocarb 20 2019, Leiden, Netherlands, 30.06.2019 - 04.07.2019]
Schmelzer, B; Grünwald-Gruber, C; Altmann, F; Gasser, B; Mattanovich, D
(2019): Analysis of intracellular interaction partners of recombinant proteins in Pichia pastoris.
[Poster]
[RPP10 2019, Crete, Greece, 24.04.2012 - 27.04.2019]
Valli, M; Grillitsch, KH; Grünwald-Gruber, C; Tatto, NE; Hrobath, B; Klug, L; Ivashov, V; Hauzmayer, S; Koller, M; Leisch, F; Gasser, B; Graf AB; Altmann, F; Daum, G; Mattanovich D
(2019): Subcellular proteome atlas of the yeast Komagataella phaffii.
[Poster]
[PYFF7 2019, Milan, Italy, 24.06.2019 - 27.06.2019]
** Castilho, A; Beihammer, G; Pfeiffer, C; Goritzer, K; Montero-Morales, L; Vavra, U; Maresch, D; Grunwald-Gruber, C; Altmann, F; Steinkellner, H; Strasser, R An oligosaccharyltransferase from Leishmania major increases the N-glycan occupancy on recombinant glycoproteins produced in Nicotiana benthamiana.
** Gludovacz, E; Maresch, D; de Carvalho, LL; Puxbaum, V; Baier, LJ; Sutzl, L; Guedez, G; Grunwald-Gruber, C; Ulm, B; Pils, S; Ristl, R; Altmann, F; Jilma, B; Salminen, TA; Borth, N; Boehm, T Oligomannosidic glycans at Asn-110 are essential for secretion of human diamine oxidase.
J BIOL CHEM. 2018; 293(3): 1070-1087. WoS PubMed FullText FullText_BOKU** Hemmer, W; Altmann, F; Holzweber, F; Gruber, C; Wantke, F; Wohrl, S ImmunoCAP cellulose displays cross-reactive carbohydrate determinant (CCD) epitopes and can cause false-positive test results in patients with high anti-CCD IgE antibody levels.
J ALLERGY CLIN IMMUN. 2018; 141(1): 372-+. WoS PubMed FullText FullText_BOKU** Kallolimath, S; Gruber, C; Steinkellner, H; Castilho, A Promoter Choice Impacts the Efficiency of Plant Glyco-Engineering.
BIOTECHNOL J. 2018; 13(1): WoS PubMed FullText FullText_BOKU** Marx, N; Grunwald-Gruber, C; Bydlinski, N; Dhiman, H; Ngoc Nguyen, L; Klanert, G; Borth, N CRISPR-Based Targeted Epigenetic Editing Enables Gene Expression Modulation of the Silenced Beta-Galactoside Alpha-2,6-Sialyltransferase 1 in CHO Cells.
** Pekarsky, A; Veiter, L; Rajamanickam, V; Herwig, C; Grunwald-Gruber, C; Altmann, F; Spadiut, O Production of a recombinant peroxidase in different glyco-engineered Pichia pastoris strains: a morphological and physiological comparison.
Grünwald-Gruber, C; Thader, A; Urteil, J; Maresch, D; Altmann, F;
(2018): Analysis of mouse brain N-glycans by (PGC-)LC-ESI-MS using isotopically labeled standards.
[Poster]
[22nd International Mass Spectrometry Conference IMSC 2018, Florence, Italy, 26.08.2018 - 31.08.2018]
Maresch, D; Grünwald-Gruber, C; Thader, A; Altmann, F
(2018): Multiplexed isotope labeled standards for isomeric analysis of N-glycans.
[Poster]
[22nd International Mass Spectrometry Conference IMSC 2018, Florence, Italy, 26.08.2018 - 31.08.2018]
Marsalek, L; Gruber, C; Altmann, F; Mattanovich, D; Puxbaum, V; Gasser, B;
(2018): Engineering vacuolar sorting pathways for efficient secretion of recombinant proteins.
[Poster]
[Microbial Engineering, Santa Fe, NM, USA, 04.03.2018 - 08.03.2018]
Marsalek, L; Puxbaum, V; Gruber-Grünwald, C; Altmann, F; Mattanovich, D; Gasser, B
(2018): Characterizing vacuolar protein sorting pathways for enhanced protein secretion in the yeast Pichia pastoris (Komagatella spp).
[Poster]
[Non-conventional yeasts: from basic research to application 2018, Rzeszow, Poland, 15.05.2018 - 18.05.2018]
Radoman, B; Grünwald-Gruber, C; Rebnegger, C; Schmelzer, B; Altmann, F; Mattanovich, D; Gasser, B
(2018): Characterization of O-glycosylation in recombinant Pichia pastoris.
[Poster]
[EMBO Workshop - Enzymes, biocatalysis ans chemical biology: The new frontiers, Pavia, Italy, 09.09.2018 - 12.09.2018]
Radoman, B; Grünwald-Gruber, C; Schmelzer, B; Gasser, B; Mattanovich, D; Altmann, F
(2018): Characterization of O-glycans in recombinant proteins produces in Pichia pastoris, .
[Poster]
[EMBO Practical Course - Characterization of post translational modifications in cellular signaling, Odense, Denmark, 19.04.2018 - 26.04.2018]
** Grunwald-Gruber, C; Altmann, F Letter to the Editor regarding "Analysis of recombinant human follicle-stimulating hormone by mass spectrometric approaches".
ANAL BIOANAL CHEM. 2017; 409(15): 3899-3900. WoS PubMed FullText FullText_BOKU** Grunwald-Gruber, C; Thader, A; Maresch, D; Dalik, T; Altmann, F Determination of true ratios of different N-glycan structures in electrospray ionization mass spectrometry.
ANAL BIOANAL CHEM. 2017; 409(10): 2519-2530. WoS PubMed FullText FullText_BOKU** Hennicke, J; Lastin, AM; Reinhart, D; Grünwald-Gruber, C; Altmann, F; Kunert, R; Glycan profile of CHO derived IgM purified by highly efficient single step affinity chromatography..
Anal Biochem. 2017; 539:162-166 WoS PubMed FullText FullText_BOKU** Marsalek, L; Gruber, C; Altmann, F; Aleschko, M; Mattanovich, D; Gasser, B; Puxbaum, V; Disruption of genes involved in CORVET complex leads to enhanced secretion of heterologous carboxylesterase only in protease deficient Pichia pastoris..
Biotechnol J. 2017; 12(5): WoS PubMed FullText FullText_BOKU** Mocsai, RT; Maczo, A; Grunwald-Gruber, C; Majer-Baranyi, K; Adanyi, N; Milotay, P; Czelecz, J; Tmskzi-Farkas, R INVESTIGATION OF ALLERGEN PROTEINS IN FIVE TOMATO CULTIVARS.
ACTA ALIMENT HUNG. 2017; 46(3): 369-377. WoS FullText FullText_BOKU** Shin, YJ; Castilho, A; Dicker, M; Sadio, F; Vavra, U; Grunwald-Gruber, C; Kwon, TH; Altmann, F; Steinkellner, H; Strasser, R Reduced paucimannosidic N-glycan formation by suppression of a specific beta-hexosaminidase from Nicotiana benthamiana.
Gasser, B; Marsalek, L; Gruber, C; Altmann, F; Mattanovich, D; Puxbaum, V;
(2017): Characterizing vacuolar protein sorting pathways
in the yeast Pichia pastoris.
[28th International Conference on Yeast Genetics and Molecular Biology ICYGMB 2017, Prague, Czech Republic, 27.08.2017 - 01.09.2017]
Grünwald-Gruber, C; Maresch, D; Altmann, F;
(2017): Portraying the sweet and the dark sides of a protein.
[Poster]
[European Summit of Industrial Biotechnology ESIB 2017, Graz, Austria, 14.11.2017 - 16.11.2017]
Grünwald-Gruber, C: Thader, A; Maresch, D; Dalik, T; Altmann, F
(2017): Determination of true ratios of different N-glycan structures in electrospray ionization-mass spectrometry.
[Austrian Proteomics and Metabolomics Research Symposium APRS 2017, Graz, Austria, 06.09.2017 - 08.09.2017]
Grünwald-Gruber, C; Thader, A; Maresch, D; Dalik, T; Altmann, F
(2017): Determination of true ratios of different N-glycan structures in electrospray ionization-mass spectrometry.
[28th MassSpec Forum Vienna 2017, Vienna, Austria, 16.02.2017 - 17.02.2017]
Grünwald-Gruber, C; Thader, A; Maresch, D; Hirtler, L; Altmann, F
(2017): Analysis of human brain N-glycans by (PGC-)LC-ESI-MS using isotopically labeled standards.
[16th Human Proteome Organization World Congress 2017, Dublin, Ireland, 17.09.2017 - 21.09.2017]
Maresch, D; Göritzer, K; Grünwald-Gruber, C; Strasser, R; Altmann, F
(2017): Site-specific N-glycosylation analysis of human IgA isotypes produced in glyco-engineered plants by LC-ESI-MS.
[Poster]
[16th Human Proteome Organization World Congress 2017, Dublin, Ireland, 17.09.2017 - 21.09.2017]
Marsalek, L; Grünwald-Gruber, C; Altmann, F; Mattanovich, D; Puxbaum, V; Gasser, B;
(2017): Characterizing Vacuolar Protein Sorting Pathways in the Yeast Pichia Pastoris.
[Poster]
[European Summit of Industrial Biotechnology ESIB 2017, Graz, Austria, 14.11.2017 - 16.11.2017]
Mócsai, RT; Grünwald-Gruber, C; Milotay, P; Gasztonyi, M; Tömösközi-Farkas, R
(2017): Simultaneous identification and relative quantification of 16 putative allergens from tomato.
[Poster]
[19th EuroFoodChem Conference 2017, Budapest, Hungary, 04.10.2017 - 06.10.2017]
Radoman, B; Grünwald-Gruber, C; Schmelzer, B; Gasser, B; Altmann, F; Mattanovich, D;
(2017): Characterization of O-glycans in recombinant proteins produced in Pichia pastoris.
[Poster]
[European Summit of Industrial Biotechnology ESIB 2017, Graz, Austria, 14.11.2017 - 16.11.2017]
Radoman, B; Grünwald-Gruber, C; Schmelzer, B; Gasser, B; Altmann, F; Mattanovich, D;
(2017): Characterization of O-glycans in recombinant proteins produced in Pichia pastoris.
[Poster]
[9th International Conference on Recombinant Protein Production RPP9 2017, Dubrovnik, Croatia, 23.04.2017 - 25.04.2017]
Schmelzer, B; Grünwald-Gruber, C; Altmann, F; Gasser, B; Mattanovich, D;
(2017): Identification of intracellular interaction partners of recombinant proteins.
[Poster]
[European Summit of Industrial Biotechnology ESIB 2017, Graz, Austria, 14.11.2017 - 16.11.2017]
Schmelzer, B; Grünwald-Gruber, C; Altmann, F; Gasser, B; Mattanovich, D;
(2017): Identification of intracellular interaction partners of recombinant proteins .
[Poster]
[9th International Conference on Recombinant Protein Production RPP9 2017, Dubrovnik, Croatia, 23.04.2017 - 25.04.2017]
** Gacek-Matthews, A; Berger, H; Sasaki, T; Wittstein, K; Gruber, C; Lewis, ZA; Strauss, J; KdmB, a Jumonji Histone H3 Demethylase, Regulates Genome-Wide H3K4 Trimethylation and Is Required for Normal Induction of Secondary Metabolism in Aspergillus nidulans..
** Kallolimath, S; Castilho, A; Strasser, R; Grunwald-Gruber, C; Altmann, F; Strubl, S; Galuska, CE; Zlatina, K; Galuska, SP; Werner, S; Thiesler, H; Werneburg, S; Hildebrandt, H; Gerardy-Schahn, R; Steinkellner, H Engineering of complex protein sialylation in plants.
P NATL ACAD SCI USA. 2016; 113(34): 9498-9503. WoS PubMed FullText FullText_BOKU** Valli, M; Tatto, NE; Peymann, A; Gruber, C; Landes, N; Ekker, H; Thallinger, GG; Mattanovich, D; Gasser, B; Graf, AB; Curation of the genome annotation of Pichia pastoris (Komagataella phaffii) CBS7435 from gene level to protein function..
FEMS Yeast Res. 2016; 16(6): WoS PubMed FullText FullText_BOKU** Zeitlin, L; Geisbert, JB; Deer, DJ; Fenton, KA; Bohorov, O; Bohorova, N; Goodman, C; Kim, D; Hiatt, A; Pauly, MH; Velasco, J; Whaley, KJ; Altmann, F; Gruber, C; Steinkellner, H; Honko, AN; Kuehne, AI; Aman, MJ; Sahandi, S; Enterlein, S; Zhan, XG; Enria, D; Geisbert, TW Monoclonal antibody therapy for Junin virus infection.
P NATL ACAD SCI USA. 2016; 113(16): 4458-4463. WoS FullText FullText_BOKU
Hofbauer, S., Grünwald-Gruber, C., Schaffner, I., Sündermann, A., Jakopitsch, C., Oostenbrink, C., Djinovic-Carugo, K., Furtmüller, P.G., Obinger, C.
(2016): Dioxygen evolution by chlorite dismutase depends on co-ordination of transiently produced hypochlorite to an oxoiron(IV) intermediate.
[79th Harden Conference on Oxygen Evolution and Reduction, Innsbruck, Austria, 16.04.2016 - 20.04.2016]
Hohlweg, J; Gruber, C; Altmann, F; Valli, M; Mattanovich, D; Gasser, B;
(2016): Secretome diversity of Pichia pastoris in the presence of different carbon sources.
[Poster]
[ESIB 2016, Graz, Austria, 14.11.2016 - 16.11.2016]
Rußmayer, H; Buchetics, M; Gruber, C; Valli, M; Grillitsch, K; Modarres, G; Drexler, H; Steiger, M; Daum, G; Graf, A; Altmann, F; Hann, S; Sauer, M; Mattanovich, D; Gasser, B;
(2016): Methanol metabolism revisited: The xylulose-monophosphate cycle of methanol assimilation utilizes a duplicated methanol inducible enzyme set and is entirely localized to peroxisomes.
[Pichia 2016, Antalya, Turkey, 03.04.2016 - 06.04.2016]
Rußmayer, H; Buchetics, M; Gruber, C; Valli, M; Grillitsch, K; Modarres, G; Drexler, H; Steiger, M; Daum, G; Graf, A; Altmann, F; Hann, S; Sauer, M; Mattanovich, D; Gasser, B;
(2016): Systems-level organization of yeast methylotrophic lifestyle: The xylulose-monophosphate cycle of methanol assimilation utilizes a duplicated methanol inducible enzyme set and is entirely localized to peroxisomes .
[PYFF6 - 6th Conference on Physiology of Yeasts and Filamentous Fungi, Lisbon, Portugal, 11.07.2016 - 14.07.2016]
Schmelzer, B; Grünwald-Gruber, C; Altmann, F; Gasser, B; Mattanovich, D;
(2016): Identification of intracellular interaction partners of recombinant proteins.
[Poster]
[ESIB – European Summit of Industrial Biotechnology, Graz, Austria, 14.11.2016 - 16.11.2016]
Valli, M; Peymann, A; Gruber, C; Tatto, N; Mattanovich, D; Gasser, B; Graf, A;
(2016): Curation of the Pichia pastoris genome annotation by integration of RNA-Seq and proteomic data.
[Pichia 2016, Antalya, Turkey, 03.04.2016 - 06.04.2016]
Valli, M; Tatto, N; Peymann, A; Gruber, C; Landes, N; Ekker, H; Thallinger, G; Mattanovich, D; Gasser, B; Graf, A
(2016): Curation of the Pichia pastoris (Komagatella phaffi) genome annotation by integration of RNA-Seq and proteomic data.
[Poster]
[ESIB 2016, Graz, Austria, 14.11.2016 - 16.11.2016]
** Castilho, A; Gruber, C; Thader, A; Oostenbrink, C; Pechlaner, M; Steinkellner, H; Altmann, F Processing of complex N-glycans in IgG Fc-region is affected by core fucosylation.
MABS-AUSTIN. 2015; 7(5): 863-870. WoS PubMed FullText FullText_BOKU** Friedrich, V; Gruber, C; Nimeth, I; Pabinger, S; Sekot, G; Posch, G; Altmann, F; Messner, P; Andrukhov, O; Schaffer, C Outer membrane vesicles of Tannerella forsythia: biogenesis, composition, and virulence.
MOL ORAL MICROBIOL. 2015; 30(6): 451-473. WoS PubMed FullText FullText_BOKU** Gacek-Matthews, A; Noble, LM; Gruber, C; Berger, H; Sulyok, M; Marcos, AT; Strauss, J; Andrianopoulos, A; KdmA, a histone H3 demethylase with bipartite function, differentially regulates primary and secondary metabolism in Aspergillus nidulans..
Mol Microbiol. 2015; 96(4):839-860 WoS PubMed FullText FullText_BOKU** Heiss, S; Puxbaum, V; Gruber, C; Altmann, F; Mattanovich, D; Gasser, B Multistep processing of the secretion leader of the extracellular protein Epx1 in Pichia pastoris and implications for protein localization.
MICROBIOL-SGM. 2015; 161: 1356-1368. WoS PubMed FullText FullText_BOKU** Plattner, S; Gruber, C; Stadlmann, J; Widmann, S; Gruber, CW; Altmann, F; Bohlmann, H; Isolation and Characterization of a Thionin Proprotein-processing Enzyme from Barley..
** Rußmayer, H; Buchetics, M; Gruber, C; Valli, M; Grillitsch, K; Modarres, G; Guerrasio, R; Klavins, K; Neubauer, S; Drexler, H; Steiger, M; Troyer, C; Al Chalabi, A; Krebiehl, G; Sonntag, D; Zellnig, G; Daum, G; Graf, AB; Altmann, F; Koellensperger, G; Hann, S; Sauer, M; Mattanovich, D; Gasser, B; Systems-level organization of yeast methylotrophic lifestyle..
** Schneider, J; Castilho, A; Pabst, M; Altmann, F; Gruber, C; Strasser, R; Gattinger, P; Seifert, GJ; Steinkellner, H; Characterization of plants expressing the human β1,4-galactosyltrasferase gene..
** Gasser, B; Russmayer, H; Buchetics, M; Gruber, C; Valli, M; Grillitsch, K; Modarres, G; Drexler, H; Steiger, M; Daum, G; Graf, AB; Altmann, F; Hann, S; Sauer, M; Mattanovich, D
The xylulose-monophosphate cycle of methanol assimilation utilizes a duplicated methanol inducible enzyme set and is entirely localized to peroxisomes.
[27th International Conference on Yeast Genetics and Molecular Biology ICYGMB 2015, Levico Terme, Italy, 06.09.2015 - 12.09.2015]
** Hohlweg, J; Gruber, C; Altmann, F; Valli, M; Mattanovich, D; Gasser, B
Secretome diversity of Pichia Pastoris in the presence of different carbon sources.
[27th International Conference on Yeast Genetics and Molecular Biology ICYGMB 2015, Levico Terme, Italy, 06.09.2015 - 12.09.2015]
Friedrich, V., C. Gruber, I. Nimeth, S. Pabinger, F. Altmann, P. Messner, O. Andrukhov, C. Schäffer*
(2015): Outer membrane vesicles of Tannerella forsythia: Biogenesis, composition, and virulence .
[Poster]
[2nd International Conference on Porphyromonas gingivalis and Related Species in Oral and Systemic Diseases 2015, London, UK, 23.06.2015 - 25.06.2015]
** He, JH; Lai, HF; Engle, M; Gorlatov, S; Gruber, C; Steinkellner, H; Diamond, MS; Chen, Q Generation and Analysis of Novel Plant-Derived Antibody-Based Therapeutic Molecules against West Nile Virus.
PLOS ONE. 2014; 9(3): WoS FullText FullText_BOKU** Hofbauer, S; Gruber, C; Pirker, KF; Sündermann, A; Schaffner, I; Jakopitsch, C; Oostenbrink, C; Furtmüller, PG; Obinger, C; Transiently produced hypochlorite is responsible for the irreversible inhibition of chlorite dismutase..
** Klug, L; Tarazona, P; Gruber, C; Grillitsch, K; Gasser, B; Trotzmuller, M; Kofeler, H; Leitner, E; Feussner, I; Mattanovich, D; Altmann, F; Daum, G The lipidome and proteome of microsomes from the methylotrophic yeast Pichia pastoris.
BBA-MOL CELL BIOL L. 2014; 1841(2): 215-226. WoS PubMed FullText FullText_BOKU** Loos, A; Gruber, C; Altmann, F; Mehofer, U; Hensel, F; Grandits, M; Oostenbrink, C; Stadlmayr, G; Furtmüller, PG; Steinkellner, H Expression and glycoengineering of functionally active heteromultimeric IgM in plants..
** Marzban, G; Kinaciyan, T; Maghuly, F; Brunner, R; Gruber, C; Hahn, R; Jensen-Jarolim, E; Laimer, M; Impact of sulfur and vitamin C on the allergenicity of Mal d 2 from apple (Malus domestica)..
J Agric Food Chem. 2014; 62(30):7622-7630 WoS PubMed FullText FullText_BOKU** Plattner, S; Gruber, C; Altmann, F; Bohlmann, H Self-processing of a barley subtilase expressed in E. coli.
PROTEIN EXPRES PURIF. 2014; 101: 76-83. WoS FullText FullText_BOKU** Schneider, JD; Marillonnet, S; Castilho, A; Gruber, C; Werner, S; Mach, L; Klimyuk, V; Mor, TS; Steinkellner, H Oligomerization status influences subcellular deposition and glycosylation of recombinant butyrylcholinesterase in Nicotiana benthamiana.
PLANT BIOTECHNOL J. 2014; 12(7): 832-839. WoS PubMed** van Dolleweerd, CJ; Teh, AYH; Banyard, AC; Both, L; Lotter-Stark, HCT; Tsekoa, T; Phahladira, B; Shumba, W; Chakauya, E; Sabeta, CT; Gruber, C; Fooks, AR; Chikwamba, RK; Ma, JKC Engineering, Expression in Transgenic Plants and Characterisation of E559, a Rabies Virus-Neutralising Monoclonal Antibody.
J INFECT DIS. 2014; 210(2): 200-208. WoS FullText FullText_BOKU
** Furtmuller, PG; Auer, M; Gruber, C; Pirker, K; Krioss, D; Hofbauer, S; Soudi, M; Obinger, C; Zamocky, M; Bellei, M; Battistuzzi, G
New highly stable chlorinating bacterial peroxidase with autocatalytically formed covalent heme to protein bonds.
[International Conference on Bioinorganic Chemistry ICBIC-16 2013, Grenoble, France, 22.07.2013 - 26.07.2013]
** Hofbauer, S; Gruber, C; Pirker, KF; Schaffner, I; Furtmuller, PG; Obinger, C; Hagmuller, A; Gysel, K; Mlynek, G; Kostan, J; Djinovic-Carugo, K; Bellei, M; Battistuzzi, G; Daims, H
Understanding Chlorite Dismutase from Candidatus Nitrospira defluvii.
[International Conference on Bioinorganic Chemistry ICBIC-16 2013, Grenoble, France, 22.07.2013 - 26.07.2013]
** Hofbauer, S; Gruber, C; Schaffner, I; Pirker, KF; Jakopitsch, C; Sundermann, A; Oostenbrink, C; Furtmuller, PG; Obinger, C
Understanding the inhibition mechanism of chlorite dismutase from the nitrite-oxidizing bacterium Candidatus Nitrospira defluvii.
[12th European Biological Inorganic Chemistry Conference EuroBIC 2014, Zürich, Switzerland, 24.08.2014 - 28.08.2014]
** Landes, N; Maccani, A; Leitner, C; Maurer, M; Graf, AB; Valli, M; Gruber, C; Modarres, G; Altmann, F; Gasser, B; Ernst, W; Kunert, R; Mattanovich, D Cross-species comparison of recombinant protein secretion in CHO cells and Pichia pastoris.
NEW BIOTECHNOL. 2014; 31: S4-S4. WoS FullText FullText_BOKU
** Nicolussi, A; Auer, M; Schutz, G; Gruber, C; Pirker, K; Zamocky, M; Furtmuller, PG; Obinger, C
Investigation of a prokaryotic peroxidase with a covalently bound heme b from the cyanobacterium Lyngbya sp PCC 8106.
[12th European Biological Inorganic Chemistry Conference EuroBIC 2014, Zürich, Switzerland, 24.08.2014 - 28.08.2014]
Auer, M., Nicolussi, A., Schütz, G. Gruber, C., Bellei, M., Battistuzzi, G., Furtmüller, P.G., Obinger, C
(2014): The role of the covalent heme to protein bond in the formation and reactivity of redox intermediates of a bacterial peroxidase with high homology to human peroxidases.
[OxiZymes 2014, Vienna, Austria, 01.07.2014 - 04.07.2014]
Gruber, C; Grillitsch, K-H; Klug, L; Valli, M; Gasser, B; Mattanovich, D; Daum, G; Altmann, F
(2014): Proteomic study of Pichia pastoris cell compartments
.
[Poster]
[APRS 2014, Salzburg, Austria, 22.09.2014 - 24.09.2014]
Hofbauer, S., Schaffner, I., Gruber, C., Pirker, K.F., Jakopitsch, C., Sündermann, A., Oostenbrink, C., Furtmüller, P.G., Obinger, C.
(2014): Mechanism of inhibition of chlorite dismutase.
[OxiZymes 2014, Vienna, Austria, 01.07.2014 - 04.07.2014]
** Auer, M; Gruber, C; Bellei, M; Pirker, KF; Zamocky, M; Kroiss, D; Teufer, SA; Hofbauer, S; Soudi, M; Battistuzzi, G; Furtmüller, PG; Obinger, C; A stable bacterial peroxidase with novel halogenating activity and an autocatalytically linked heme prosthetic group..
** Leymarie, N; Griffin, PJ; Jonscher, K; Kolarich, D; Orlando, R; McComb, M; Zaia, J; Aguilan, J; Alley, WR; Altmann, F; Ball, LE; Basumallick, L; Bazemore-Walker, CR; Behnken, H; Blank, MA; Brown, KJ; Bunz, SC; Cairo, CW; Cipollo, JF; Daneshfar, R; Desaire, H; Drake, RR; Go, EP; Goldman, R; Gruber, C; Halim, A; Hathout, Y; Hensbergen, PJ; Horn, DM; Hurum, D; Jabs, W; Larson, G; Ly, M; Mann, BF; Marx, K; Mechref, Y; Meyer, B; Moginger, U; Neususs, C; Nilsson, J; Novotny, MV; Nyalwidhe, JO; Packer, NH; Pompach, P; Reiz, B; Resemann, A; Rohrer, JS; Ruthenbeck, A; Sanda, M; Schulz, JM; Schweiger-Hufnagel, U; Sihlbom, C; Song, E; Staples, GO; Suckau, D; Tang, HX; Thaysen-Andersen, M; Viner, RI; An, YM; Valmuv, L; Wada, Y; Watson, M; Windwarder, M; Whittal, R; Wuhrer, M; Zhu, YY; Zou, CX Interlaboratory Study on Differential Analysis of Protein Glycosylation by Mass Spectrometry: The ABRF Glycoprotein Research Multi-Institutional Study 2012.
** Gasser, B; Heiss, S; Puxbaum, V; Gruber, C; Altmann, F; Mattanovich, D
Multistep processing of the secretion leader of the CRISP family member Epx1 in Pichia pastoris and implications on protein localization.
[26th International Conference on Yeast Genetics and Molecular Biology 2013, Frankfurt am Main, Germany, 29.08.2013 - 03.09.2013]
Auer, M. Gruber, C. Bellei, M., Pirker, K., Kroiß, D., Zamocky, M. Teufer, A. S., Soudi, M., Battistuzzi, G., Obinger, C. and Furtmüller P. G.
(2013): New highly stable chlorinating bacterial peroxidase with autocatalytically formed covalent heme to protein bonds.
[Poster]
[International Conference on Bioinorganic Chemistry ICBIC-16 2013, Grenoble, France, 22.07.2013 - 26.07.2013]
Hofbauer, S., Gruber, C., Pirker, K. F., Schaffner, I., Hagmüller, A., Gysel, K., Mlynek, G., Kostan, J., Bellei, M., Daims, H., Djinovic-Carugo, K. Battistuzzi, G., Furtmüller, P.G. and Obinger, C
(2013): Understanding highly stable chlorite dismutase form nitrate-oxidizing bacterium Candidatus “Nitrospira defluvii”.
[Poster]
[International Conference on Bioinorganic Chemistry ICBIC-16 2013, Grenoble, France, 22.07.2013 - 26.07.2013]
Auer, M. Kroiß, D. Gruber, C. Zamocky, M. Furtmüller, P.G. & Obinger, C.
(2012): Bacterial heme enzyme of high structural and funtional homology with mammaian peroxidases -characterization of the first representative of a new protein family.
[Poster]
[OxiZymes 2012, Marseille, France, 16.09.2012 - 19.09.2012]
Aufy, M; Porodko, A; Stadlmann, J; Gruber, C; Mach, L
(2012): Human cathepsin O: glycosylation, processing and cellular activity.
[13th International Symposium on Proteinases, Inhibitors and Biological Control 2012, Portoroz, Slovenia, 22.09.2012 - 26.09.2012]
** Stampler, J; Bellei, M; Soudi, M; Gruber, C; Battistuzzi, G; Furtmüller, PG; Obinger, C; Manipulating the proximal triad His-Asn-Arg in human myeloperoxidase..
Arch Biochem Biophys. 2011; 516(1):21-28 WoS PubMed FullText FullText_BOKU