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Bayer Karl

Scientific publications from BOKU scientists, especially those which are published in SCI / SSCI journals, or in other refereed journals, proceedings, monographs as well as articles in collected volumes are listed under PUBLICATIONS.

Publications with special focus on transfer of knowledge ("social impact") to practitioners as well as the interested public can be found under the menu item:

>> Transfer of Knowledge


** = Publications listed in SCI/SSCI - Journals (published in Web of Science)
* = peer-reviewed publication (not listed in SCI/SSCI)
Only: Full paper/article, Review, Proceedings Paper

= Open Access - Publications

 

2016

Conference & Workshop Proceedings, Paper, Abstract

Luchner, M.; Striedner, G.; Melcher, M.; Bayer, K.; (2016): Advanced bioprocess monitoring: A key to process and systems understanding.
[7th International PTR-MS Conference 2016, Obergurgl, Austria, 14.02.2016 - 19.02.2016]

In: Armin Hansel, Jürgen Dunkl (Hrsg.) Innsbruck University Press, Contributions 7th International Conference on Proton Transfer Reaction Mass Spectrometry and its Applications; ISBN: 978-3-903122-00-0

2015

Journal Articles

** Melcher, M; Scharl, T; Spangl, B; Luchner, M; Cserjan, M; Bayer, K; Leisch, F; Striedner, G; The potential of random forest and neural networks for biomass and recombinant protein modeling in Escherichia coli fed-batch fermentations..

Biotechnol J. 2015; 10(11):1770-1782 WoS PubMed FullText FullText_BOKU

** Toeroek, C; Cserjan-Puschmann, M; Bayer, K; Striedner, G; Fed-batch like cultivation in a micro-bioreactor: screening conditions relevant for Escherichia coli based production processes..

Springerplus. 2015; 4:490 WoS PubMed PUBMED Central FullText FullText_BOKU

2014

** Bayer, K Brief Note on the Development of Biotechnology.

FOOD TECHNOL BIOTECH. 2014; 52(1): 13-15. WoS

** Schmidberger, T; Gutmann, R; Bayer, K; Kronthaler, J; Huber, R Advanced online monitoring of cell culture off-gas using proton transfer reaction mass spectrometry.

BIOTECHNOL PROGR. 2014; 30(2): 496-504. WoS FullText FullText_BOKU

Conference & Workshop Proceedings, Paper, Abstract

Luchner, M; Striedner, G;Gutmann, R; Bayer, K; (2014): Advanced bioprocess monitoring key to process and systems understanding.
[EUROPACT 2014, Barcelona, Spain, 06.05.2014 - 09.05.2014]

In: DECHEMA (Hrsg.), Program and Book of Abstracts EuroPACT 2014 3rd European Conference on Process Analytics and Control Technology

2013

Journal Articles

** Marisch, K; Bayer, K; Cserjan-Puschmann, M; Luchner, M; Striedner, G Evaluation of three industrial Escherichia coli strains in fed-batch cultivations during high-level SOD protein production.

MICROB CELL FACT. 2013; 12: WoS PubMed PUBMED Central FullText FullText_BOKU

** Marisch, K; Bayer, K; Scharl, T; Mairhofer, J; Krempl, PM; Hummel, K; Razzazi-Fazeli, E; Striedner, G A Comparative Analysis of Industrial Escherichia coli K-12 and B Strains in High-Glucose Batch Cultivations on Process-, Transcriptome- and Proteome Level.

PLOS ONE. 2013; 8(8): WoS PubMed PUBMED Central FullText FullText_BOKU

** Striedner, G; Bayer, K An advanced monitoring platform for rational design of recombinant processes..

Adv Biochem Eng Biotechnol. 2013; 132:65-84 WoS PubMed FullText FullText_BOKU

Striedner, G; Bayer, K (2013): Considerations in upstream bioprocess monitoring and statistical data analysis in the context of process analytical technology and quality by design.

Pharmaceutical Bioprocessing, 1 (2), 159-166; ISSN 2048-9145 FullText

Conference & Workshop Proceedings, Paper, Abstract

Marisch, K; Bayer, K; Cserjan-Puschmann, M; Luchner, M; Striedner, G (2013): Evaluation of three industrial Escherichia coli strains in fed-batch cultivations during high-level protein production . [Poster]
[9th European Conference Chemical Engineering & 2nd European Conference in Applied Biotechnology ECAB 2013, The Hague, Netherlands, 21.04.2013 - 25.04.2013]

In: ECCE/ECAB, 9th European Congress of Chemical Engineering and 2nd European Congress of Applied Biotechnology

2012

Journal Articles

** Luchner, M; Gutmann, R; Bayer, K; Dunkl, J; Hansel, A; Herbig, J; Singer, W; Strobl, F; Winkler, K; Striedner, G Implementation of proton transfer reaction-mass spectrometry (PTR-MS) for advanced bioprocess monitoring.

BIOTECHNOL BIOENG. 2012; 109(12): 3059-3069. WoS PubMed FullText FullText_BOKU

Conference & Workshop Proceedings, Paper, Abstract

F. Strobl, M. Cserjan, M. Luchner, K. Marisch, K. Bayer and G. Striedner (2012): Impact of Different Induction Levels on Inclusion Body (IB) Formation Kinetics in recombinant E. coli Fed Batch Cultivations. [Poster]
[2nd BioProScale Symposium 2012 - Inhomogeneities in large-scale bioprocesses: System biology and process dynamics, Berlin, Germany, 14.03.2012 - 16.03.2012]

In: IfGB & TU-Berlin, 2nd BioProScale Symposium "Inhomogeneities in large-scale bioprocesses: System biology and process dynamics"

F. Strobl, M. Luchner, M. Cserjan, K. Bayer and G. Striedner (2012): Recombinant protein production with E. coli: implementation of an inducer feed control loop based on realtime predicted biomass . [Poster]
[Advances in Process Analytics and Control Technology APACT 12 2012, Newcastle, UK, 25.04.2012 - 27.04.2012]

In: APACT, APACT '12 - Advances in Process Analytics and Control Technology

Gerald Striedner, Markus Luchner, Rene Gutmann, Karl Bayer (2012): Advanced bioprocess monitoring key to process and systems understanding.
[15th European Congress on Biotechnology, Istanbul, Turkey, 23.09.2012 - 26.09.2012]

New Biotechnology, Volume 29, 102-102

Luchner, M; Cserjan, M; Strobl, F; Bayer, K; Striedner, G (2012): On-line prediction of soluble and insoluble recombinant protein and further key variables as quality criteria in E. coli bioprocesses.
[9th European Symposium on Biochemical Engineering ScienceESBES and 32nd International Symposium on the Separation of Proteins, Peptides and Polynucleotides ISPPP 2012, Istanbul, Turkey, 23.09.2012 - 26.09.2012]

In: ESBES, Abstract Book

M. Luchner, M. Cserjan, F. Strobl, K. Bayer and G. Striedner (2012): Recombinant gene expression in Escherichia coli - Implementation of an inducer feed control loop based on on-line predicted cell dry mass.
[PepCon 2012, Beijing, PR China, 23.03.2012 - 25.03.2012]

In: BIT Life Sciences, PepCon 2012

Markus Luchner, Rene Gutmann, Armin Hansel, Karl Bayer, Gerald Striedner (2012): Implementation of Proton Transfer Reaction - Mass Spectrometry (PTR-MS) as tool in bioprocess monitoring – measurement of volatile components in the bioreactor exhaust gas. [Poster]
[2nd BioProScale Symposium 2012 - Inhomogeneities in large-scale bioprocesses: System biology and process dynamics, Berlin, Germany, 14.03.2012 - 16.03.2012]

In: IfGB & TU-Berlin, 2nd BioProScale Symposium "Inhomogeneities in large-scale bioprocesses: System biology and process dynamics"

Rene Gutmann Markus Luchner Jens Herbig Armin Hansel Karl Bayer Gerald Striedner (2012): Advanced bioprocess monitoring by implementation of Proton Transfer Reaction - Mass Spectrometry (PTR-MS) for measurement of volatile components in the bioreactor . [Poster]
[Pichia 2012, Alpbach, Austria, 29.02.2012 - 03.03.2012]

In: ACIB, Book of abstracts

2011

Cserjan M., Strobl F., Luchner M., Marisch K., Bayer K. and Striedner G. (2011): Impact of different induction levels on Inclusion Body (IB) formation kinetics in recombinant E. coli fed batch cultivations .
[1st European Congress on Applied Biotechnology ECAP 2011, Berlin, Germany, 25.09.2011 - 29.09.2011]

In: ECCE/ECAB Dechema, 1st European Congress of Applied Biotechnology

G. Striedner, M. Luchner, M. Riepler, R. Gutmann and K. Bayer (2011): PREDICTION OF COMPLEX BIOPROCESS VARIABLE BY STATISTICAL MODELLING.
[International Workshop on Biological Products and Bioprocesses 2011, Varadero, Cuba, 26.06.2011 - 30.06.2011]

In: Cuban Society of Pharmacology (SCF) , International Workshop on Biological Products and Bioprocesses

Gerald Striedner, Markus Luchner, Rene Gutmann, Armin Hansel, Karl Bayer (2011): Measurement of volatile components in the bioreactor via Proton Transfer Reaction - Mass Spectrometry (PTR-MS) - Implementation in bioprocess monitoring.
[5th PTR-MS Conference 2011, Berlin, Germany, 18.10.2011 - 21.10.2011]

In: Informa Life Sciences, 5 th PTR-MS Conference 2011

Gerald Striedner, Markus Luchner, Rene Gutmann, Armin Hansel, Karl Bayer (2011): Measurement of volatile components in the bioreactor via Proton Transfer Reaction - Mass Spectrometry (PTR-MS) .
[1st European Congress on Applied Biotechnology ECAP 2011, Berlin, Germany, 25.09.2011 - 29.09.2011]

In: ECCE/ECAB, 1st European Congress of Applied Biotechnology

Mairhofer J., Cserjan-Puschmann M., Smolar E., Grabherr R, Bayer K., Striedner G. (2011): Integrated approach for the advanced characterization and improvement of T7-based Escherichia coli expression systems for recombinant protein production. [Poster]
[5th International Meeting on Synthetic Biology 2011, Stanford, CA, USA, 15.06.2011 - 17.06.2011]

In: Stanford University , SB5.0 - The Fifth International Meeting on Synthetic Biology

Markus Luchner, Monika Cserjan, Florian Strobl, Karl Bayer and Gerald Striedner (2011): Model based inducer feed control for repressor titration in recombinant protein expression of E. coli. [Poster]
[6th Conference on Recombinant Protein Production RPP6 2011, Vienna, Austria, 16.02.2011 - 19.02.2011]

In: EFB, Book of abstracts

Markus Luchner, Monika Cserjan, Michael Riepler, Florian Strobl, Karl Bayer and Gerald Striedner (2011): Recombinant gene expression in E. coli - Implementation of an inducer feed control loop based on on-line prediction of cell dry mass. [Poster]
[1st European Congress on Applied Biotechnology ECAP 2011, Berlin, Germany, 25.09.2011 - 29.09.2011]

In: ECCE/ECAB, 1st European Congress of Applied Biotechnology

Striedner G., Bayer K., Cserjan M., Mairhofer J., Scharl T., Marisch K., Luchner M.: , International Workshop on Biological Products and Bioprocesses, Varadero, Cuba, 26.06.2011 - 30.06.2011 (2011): Host cell response to recombinant gene expression in E. coli based expression systems.
[International Workshop on Biological Products and Bioprocesses 2011, Varadero, Cuba, 26.06.2011 - 30.06.2011]

In: Cuban Society of Pharmacology (SCF) , International Workshop on Biological Products and Bioprocesses

Striedner G., Luchner M., Gutmann R., Hansel A. and Bayer K (2011): Implementation of proton transfer reaction - mass spectrometry as a tool in bioprocess monitoring - measurement of volatile components in the bioreactor exhaust gas.
[Europact 2011, Glasgow, Scotland, UK, 26.04.2011 - 29.04.2011]

In: Dechema, Abstracts - Europact 2011

2010

Journal Articles

** Striedner, G; Pfaffenzeller, I; Markus, L; Nemecek, S; Grabherr, R; Bayer, K; Plasmid-free T7-based Escherichia coli expression systems..

Biotechnol Bioeng. 2010; 105(4):786-794 WoS PubMed FullText FullText_BOKU

Conference & Workshop Proceedings, Paper, Abstract

G. Striedner, I. Pfaffenzeller, M. Luchner , M. Cserjan, R. Grabherr and K.Bayer (2010): Plasmid-free T7-based Escherichia Coli Expression Systems-a Robust and Efficient Alternative for Recombinant Protein Production.
[3rd Annual Protein and Peptide Conference PepCon 2010, Beijing, PR China, 21.03.2010 - 23.03.2010]

In: BIT Life Sciences, Book of abstracts

G. Striedner, M. Luchner , M. Cserjan, and K.Bayer (2010): Tuning and control of recombinant gene expression for optimal exploitation of cellular capacities.
[FORSYS / JCB - International Workshop: Systems Biology for Industry: Dynamics and Regulation of the Metabolic Balance in Escherichia coli, Jena, Germany, 07.10.2010 - 08.10.2010]

In: FORSYS / JCB, International Workshop: Systems Biology for Industry: Dynamics and Regulation of the Metabolic Balance in Escherichia coli

G. Striedner, M. Luchner and K. Bayer (2010): Recombinant protein production in E. coli – process understanding the base for implementation of PAT and QbD in upstream processing.
[8th European Symposium on Biochemical Engineering Science together with 3rd International Symposium on Biothermodynamics M3C Workshop ESBES-8 /ESBES – ISPPP 3 – Biothermo 2010, Bologna, Italy, 05.09.2010 - 08.09.2010]

In: M3C - ESBES – ISPP,

Markus Luchner, Monika Cserjan, Gerald Striedner , Florian Strobl and Karl Bayer (2010): Application of multiple in- and on-line sensor devices combined with MVDA for advanced bioprocess monitoring as a supporting tool for the FDA´s PAT initiative. [Poster]
[2nd ÖGMBT Annual Meeting 2010, Vienna, Austria, 27.09.2010 - 29.09.2010]

In: OEGMBT , Book of abstracts

2009

Journal Articles

** Kaar, W; Ahrer, K; Dürauer, A; Greinstetter, S; Sprinzl, W; Wechner, P; Clementschitsch, F; Bayer, K; Achmüller, C; Auer, B; Hahn, R; Jungbauer, A Refolding of Npro fusion proteins..

Biotechnol Bioeng. 2009; 104(4):774-784 WoS PubMed FullText FullText_BOKU

** Leparc, GG; Tüchler, T; Striedner, G; Bayer, K; Sykacek, P; Hofacker, IL; Kreil, DP; Model-based probe set optimization for high-performance microarrays..

Nucleic Acids Res. 2009; 37(3):e18 WoS PubMed PUBMED Central FullText FullText_BOKU

** Scharl, T; Striedner, G; Pötschacher, F; Leisch, F; Bayer, K; Interactive visualization of clusters in microarray data: an efficient tool for improved metabolic analysis of E. coli..

Microb Cell Fact. 2009; 8:37 WoS PubMed PUBMED Central FullText FullText_BOKU

Conference & Workshop Proceedings, Paper, Abstract

Klose, V; Bayer, K; Bruckbeck, R; Loibner, AP; Schatzmayr, G (2009): Antagonistic strains isolated from the porcine gastrointestinal tract. [Poster]
[Joint Annual Meeting ADSA-CSAS-ASAS 2009, Montreal, QC, Canada, 12.07.2009 - 16.07.2009]

Klose, V; Bayer, K; Bruckbeck, R; Sattler, VA; Loibner, AP; Mair, C; Schatzmayr, G (2009): Selection of probiotic strains for combined competitive exclusion treatment in piglets.
[Joint Annual Meeting ADSA-CSAS-ASAS 2009, Montreal, QC, Canada, 12.07.2009 - 16.07.2009]

Klose, V; Bayer, K; Schmuckenschlager, P; Bruckbeck, R; Henikl, S; Loibner, AP; Schatzmayr, G (2009): Selection of potential probiotic strains for competitive exclusion treatment in pork production. [Poster]
[11th International Symposium on Digestive Physiology of Pigs 2009, Montbrio del Camp, Spain, 20.05.2009 - 22.05.2009]

Markus Luchner, Norbert Auer, Karl Bayer (2009): Application of multiple in- and on-line sensor devices combined with chemometrics for advanced bioprocess monitoring in view of the FDA´s PAT initiative .
[Annual Meeting IFPAC 2009, Baltimore, MD, USA, 25.01.2009 - 28.01.2009]

In: IPFAC, IFPAC - 2009 Twenty-third inernational forum Process Analytical Technology

2008

Journal Articles

** Dürrschmid, K; Reischer, H; Schmidt-Heck, W; Hrebicek, T; Guthke, R; Rizzi, A; Bayer, K Monitoring of transcriptome and proteome profiles to investigate the cellular response of E. coli towards recombinant protein expression under defined chemostat conditions..

J Biotechnol. 2008; 135(1):34-44 WoS PubMed FullText FullText_BOKU

** Margreiter, G; Messner, P; Caldwell, KD; Bayer, K; Size characterization of inclusion bodies by sedimentation field-flow fractionation..

J Biotechnol. 2008; 138(3-4):67-73 WoS PubMed PUBMED Central FullText FullText_BOKU

** Nemecek, S; Marisch, K; Juric, R; Bayer, K Design of transcriptional fusions of stress sensitive promoters and GFP to monitor the overburden of Escherichia coli hosts during recombinant protein production..

Bioprocess Biosyst Eng. 2008; 31(1):47-53 WoS PubMed FullText FullText_BOKU

** Pinsach, J; de Mas, C; Lopez-Santin, J; Striedner, G; Bayer, K Influence of process temperature on recombinant enzyme activity in Escherichia coli fed-batch Cultures.

ENZYME MICROB TECHNOL. 2008; 43(7): 507-512. WoS FullText FullText_BOKU

* Margreiter, G; Schwanninger, M; Bayer, K; Obinger, C; (2008): Impact of different cultivation and induction regimes on the structure of cytosolic inclusion bodies of TEM1-beta-lactamase..

Biotechnol J. 2008; 3(9-10):1245-1255 PubMed FullText FullText_BOKU

Conference & Workshop Proceedings, Paper, Abstract

G. Striedner, I. Pfaffenzeller, M. Luchner , S. Nemecek, R. Grabherr and K.Bayer (2008): Plasmid-free T7-based Escherichia coli expression systems - a robust and efficient alternative for recombinant protein production.
[5th EFB Meeting on Recombinant Protein Production RPP 2008, Sardinia, Italy, 24.09.2008 - 28.09.2008]

In: EFB Microbial Physiology Section, Recombinant Protein Production, An integrated view of host physiology - Book of abstracts

2007

Journal Articles

** Achmüller, C., Kaar, W., Ahrer, K., Wechner, P., Hahn, R., Werther, F., Schmidinger, H., Cserjan-Puschmann, M., Clementschitsch, F., Striedner, G., Bayer, K., Jungbauer, A., Auer, B. Npro fusion technology to produce proteins with authentic N termini in E. coli.

NAT METHODS, 4 (12), 1037-1043; ISSN 1548-7091 WoS PubMed FullText FullText_BOKU

** Bayer, K; Jungbauer, A Advances in biochemical engineering science..

J Biotechnol. 2007; 132(2):97-98 WoS PubMed FullText FullText_BOKU

** Gross-Selbeck, S; Margreiter, G; Obinger, C; Bayer, K Fast quantification of recombinant protein inclusion bodies within intact cells by FT-IR spectroscopy..

Biotechnol Prog. 2007; 23(3):762-766 WoS PubMed FullText FullText_BOKU

** Hrebicek, T; Duerrschmid, K; Auer, N; Bayer, K; Rizzi, A Effect of CyDye minimum labeling in differential gel electrophoresis on the reliability of protein identification.

ELECTROPHORESIS. 2007; 28(7): 1161-1169. WoS PubMed FullText FullText_BOKU

Conference & Workshop Proceedings, Paper, Abstract

** Gross-Selbeck, S; Margreiter, G; Obinger, C; Bayer, K Quantification of recombinant protein expression in the form of inclusion bodies within E-coli by using FT-IR spectroscopy.

J BIOTECHNOL. 2007; 131(2): S153-S153. WoS FullText FullText_BOKU

2006

Journal Articles

** Schultz, T; Martinez, L; de Marco, A The evaluation of the factors that cause aggregation during recombinant expression in E. coli is simplified by the employment of an aggregation-sensitive reporter..

Microb Cell Fact. 2006; 5(1):28-28 WoS PubMed PUBMED Central FullText FullText_BOKU

* Müller D, Bayer K, Mattanovich D (2006): Potentials and limitations of prokaryotic and eukaryotic expression systems for recombinant protein production – a comparative view.

Microbial cell factories [Elektronische Ressource], 5(Suppl 1), p61; ISSN 1475-2859 FullText

* Pfaffenzeller, I; Mairhofer, J; Striedner, G; Bayer, K; Grabherr, R (2006): Using ColE1-derived RNA I for suppression of a bacterially encoded gene: implication for a novel plasmid addiction system..

Biotechnol J. 2006; 1(6):675-681 PubMed FullText FullText_BOKU

Conference & Workshop Proceedings, Paper, Abstract

Karl Bayer (2006): Advances in Bioprocess Monitoring and Control.
[Bioprocess International Europesan Conference 2006, Prague, Czech Republic, 21.02.2006]

In: IBC LIfe Sciences Informa Life science Group: Bioprocess International Europes Leading Bioprocessing Event, 21. - 2... February 2006, Prague

Nemecek,S., Juric,R., Marisch,K., Bayer K., (2006): Design of transcriptional fusions of stress sensitive promoters and GFP to monitor the overburden of E.coli hosts during recombinant protein production..
[4th Recombinant Protein Production Meeting RPP EFB 2006 - A Comparative View on Host Physiology, Barcelona, Spain, 21.09.2006 - 23.09.2006]

In: RPP2006: 4th Recombinant Protein Production Meeting, September 21-23 2006, Barcelona, Spain

Nemecek,S., Juric,R., Marisch,K., Bayer,K., (2006): Design of promoter-GFP fusions for monitoring of stress during recombinant protein production..
[6th European Symposium on Biochemical Engineering Science ESBES6 2006, Salzburg, Austria, 27.08.2006 - 30.08.2006]

In: ESBS 6: 6th European Symposium on Biochemical Engineering Science, 27-30 August 2006, Salzburg, Austria

Pfaffenzeller, I., Mairhofer, J., Striedner, G., Bayer, K., Grabherr, R. (2006): A novel approach for antibiotic free selection of recombinant plasmids for gene therapeutic applications based on RNA antisense reaction.
[Joint Annual Meeting of the ÖGBM, ÖGGGT, ÖGBT and ANGT, Salzburg, Austria, 01.09.2006]

In: ÖGBT/ÖGGGT: Joint Annual Meeting of the ÖGBT, ÖGBM, ÖGGGT and ANGT, September 2006, Salzburg, Austria

2005

Journal Articles

** Clementschitsch, F; Kern, J; Pötschacher, F; Bayer, K Sensor combination and chemometric modelling for improved process monitoring in recombinant E. coli fed-batch cultivations..

J Biotechnol. 2005; 120(2):183-196 WoS PubMed FullText FullText_BOKU

Conference & Workshop Proceedings, Paper, Abstract

** Bayer, K Application of advanced monitoring strategies for recombinant protein production.

J BIOTECHNOL. 2005; 118: S36-S36. WoS

** Durrschmid, K; Reischer, H; Schmidt-Heck, W; Hrebicek, T; Guthke, R; Rizzi, A; Bayer, K Monitoring the dynamics of transcription and translation within the time course of recombinant E-coli cultivations.

MOL CELL PROTEOMICS. 2005; 4(8): S285-S285. WoS

Bayer K. (2005): Monitoring of stress response during recombinant protein production in E. coli on transcriptome and proteome level.
[NiSIS/JCB Workshop, Jena, Germany, 01.01.2005]

In: R. Guthke, M. Pfaff: NiSIS/JCB Workshop, Reverse engineering in Systems Biology, Jena

Dürrschmid, K. , Reischer, H., Schmidt-Heck, W., Hrebicek, T., Auer, N., Margreiter, G., Guthke, R., Rizzi A., Bayer, K. (2005): In-depth monitoring of recombinant E.coli cultivations.
[3rd Austrian Proteome Research Symposium 2005, Vienna, Austria, 28.09.2005 - 29.09.2005]

In: 3rd Austrian Proteome Research Symposium: 3rd Austrian Proteome Research Symposium, 28. –29. September 2005, Institute of Chemical Technologies and Analytics at the Vienna University of Technology

Dürrschmid, K. , Reischer, H., Schmidt-Heck, W., Hrebicek, T., Auer, N., Margreiter, G., Guthke, R., Rizzi A., Bayer, K. (2005): Monitoring the Dynamic of Transcription and Translation within the Time Course of Recombinant E. coli Cultivations.
[Life Sciences 2005, Joint Annual Meeting of ÖGBM, ÖGGGT, ÖGBT and ANGT, Vienna, Austria, 26.09.2005 - 28.09.2005]

In: Joint Annual Meeting 2005: ÖGBM, ÖGGGT, ÖGBT, ANGT: Joint Annual Meeting 2005: ÖGBM, ÖGGGT, ÖGBT, ANGT, 26.-28. September 2005, University of Natural Resources and Applied Life Sciences, Vienna, 24

K. Dürrschmid, H. Reischer, N. Auer, G. Margreiter, W. Schmidt-Heck, T. Hrebicek, R. Guthke, A. Rizzi, K. Bayer (2005): Acceleration of process development of recombinant fermentations by monitoring the dynamics of transcription and translation.
[GVC‐DECHEMA‐Tagung 2005 - Systembiotechnologie für industrielle Prozesse, Braunschweig, Germany, 01.05.2005 - 04.05.2005]

In: DECHEMA/GVC: Systembiotechnologie für industrielle Prozesse, 2005, Braunschweig,

K. Dürrschmid, H. Reischer, N. Auer, W. Schmidt-Heck, T. Hrebicek, R. Guthke, A. Rizzi, K. Bayer, (2005): Monitoring the dynamics of transcription and translation in the time course of recombinant cultivations.
[4th Annual World Congress of the Human Proteome Organization 2005, Munich, Germany, 29.08.2005 - 01.09.2005]

In: Human Proteome Organization: Human Proteome Organization, 4th Annual World Congress, ,, 29 August -1 September 2005, ICM München, Deutschland

Karl Bayer (2005): Analysis of metabolic control strategies.
[NiSIS 2005, First European Symposium on Nature-inspired Smart Information Systems,, Albufeira, Portugal, 03.10.2005 - 05.10.2005]

In: ELITE Foundation, Pascalstr. 69, 52076 Aachen: NiSIS 2005, First European Symposium on Nature-inspired Smart Information Systems,, 3 - 5 October 2005, Albufeira, Portugal FullText

Pfaffenzeller, I., Mairhofer, J., Striedner, G., Bayer, K., Grabherr, R. (2005): A novel approach for antibiotic-free selection of recombinant plasmids for gene therapeutic applications based on RNA antisense reaction.
[Protein expression in animal cells 2005, Hersonissos, Greece, 18.09.2005 - 22.09.2005]

In: PEACe: protein expression in animal cells, 18. -22. Sept. 2005, Hersonnisos, Crete, Greece

Zehentner-Nemecek,S., Juric,R., Bayer,K., (2005): Monitoring of stress response during recombinant protein production in E.coli..
[Life Sciences 2005, Joint Annual Meeting of ÖGBM, ÖGGGT, ÖGBT and ANGT, Vienna, Austria, 26.09.2005 - 28.09.2005]

In: ÖGBT: ÖGBT: ÖGBT, ÖGGGT, ÖGMB, ANGT Annual Joint Meeting 2005, 26. -28. September 2005, Vienna, Austria

2004

Journal Articles

** Reischer, H; Schotola, I; Striedner, G; Pötschacher, F; Bayer, K Evaluation of the GFP signal and its aptitude for novel on-line monitoring strategies of recombinant fermentation processes..

J Biotechnol. 2004; 108(2):115-125 WoS PubMed FullText FullText_BOKU

Patents

Bayer K., Grabherr, R., Nilsson, E., Striedner, G. (2004): Expression vectors with modified ColE1 origin of replication for control of plasmid copy number.

, 19. 10. 2004; US 6,806,066 B2

Conference & Workshop Proceedings, Paper, Abstract

Striedner G., Clementschitsch F., Cserjan M., Dürrschmid K., Reischer H., Bayer K. (2004): Metabolic and Engineering Integration Approach for the Optimisation of Recombinant Microbial Fermentation Processes.
[1st Workshop on Enzyme Technology and Biocatalysis, 2004, Graz, Austria, 25.11.2004 - 26.11.2004]

In: Kompetenzzentrum Angewandte Biokatalyse,: 1st Workshop Enzyme Technology and Biocatalysis, 25.11.2004 bis 26.11.2004, Graz, Österreich FullText

2003

Journal Articles

** Dürrschmid, K; Marzban, G; Dürrschmid, E; Striedner, G; Clementschitsch, F; Cserjan-Puschmann, M; Bayer, K Monitoring of protein profiles for the optimization of recombinant fermentation processes using public domain databases..

Electrophoresis. 2003; 24(1-2):303-310 WoS PubMed FullText FullText_BOKU

** Gerald Striedner, Monika Cserjan-Puschmann, Florentina Pötschacher, Karl Bayer Tuning the Transcription Rate of Recombinant Protein in Strong Escherichia coli Expression Systems through Repressor Titration.

Biotechnology Progress, 19 , 1427 - 143 WoS FullText FullText_BOKU

Conference & Workshop Proceedings, Paper, Abstract

Bayer K. (2003): Integrated Systems Approach for the Optimization of Recombinant Fermentation Processes.
[225th National Spring Meeting of the American Chemical Society ACS 2003, New Orleans, LA, USA, 23.03.2003 - 27.03.2003]

In: ACS: 225th ACS National Meeting, March 23-27, 2003, New Orleans, Louisiana

Bayer K. (2003): Optimal Exploitation of the E.coli Cell Factory by an Integrated Approach.
[Halle Conference on Recombinant Protein Production", Halle, Germany, 27.02.2003 - 01.03.2003]

In: Rudolph: Halle Conference on Recombinant Protein Production", 27.02.2003 - 01.03.2003, Halle

Cserjan-Puschmann, M., Striedner, G., Clementschitsch, F. , Dürrschmid, K. , Kern, J., Pötschacher, F. , Reischer, H., Bayer, K. (2003): Metabolic and engineering integration approach for the optimisation of recombinant microbial fermentation processes.
[1st FEMS Congress of European Microbiologists 2003, Ljubljana, Slovenia, 29.06.2003 - 03.07.2003]

In: Federation of European Microbiological Societies: 1st FEMS Congress of European Microbiologists, 2003 June 29 - 2003 July 3, Cankarjev Dom Ljubljana, SLOVENIA; Elsevier, Abstract book; ISSN 0378-1097

Faber, R., Compton, K., Ermolieva, T., Bayer, J., Nachtnebel, H.P. (2003): Flood Risk Assessment and Management for Vienna's Subway. Facing Uncertainties and Temporal Changes.
[Third DPRI-IIASA International Symposium on INTEGRATED DISASTER RISK MANAGEMENT (IDRM-2003), Kyoto, Japan, 03.07.2003 - 05.07.2003]

In: Disaster Prevention Research Institute(DPRI) of the Kyoto University and International Institute of Applied Systems Analysis(IIASA), Laxenburg, Austria: Third DPRI-IIASA International Symposium on INTEGRATED DISASTER RISK MANAGEMENT (IDRM-2003), 3-5 July, 2003 , Kyoto International Conference Hall Kyoto, JAPAN, 17, Kyoto, JAPAN FullText

Striedner G., Cserjan M., Pötschacher F., Bayer K. (2003): Tuning the transcription rate of recombinant protein in strong Escherichia coli expression systems through repressor titration.
[1st FEMS Congress of European Microbiologists 2003, Ljubljana, Slovenia, 29.06.2003 - 03.07.2003]

In: Federation of European Microbiological Societies: 1st FEMS Congress of European Microbiologists, 2003 June 29 - 2003 July 3, Cankarjev Dom Ljubljana, SLOVENIA; Abstract book, 243; Elsevier; ISSN 0378-1097

W. Schmidt-Heck, K. Dürrschmid, H. Reischer and K. Bayer, R. Guthke (2003): Computational Data And Knowledge Based Analysis of Stress Response on Transcriptome Level in Recombinant Escherichia coli.
[DECHEMA-Statusseminar: Chiptechnologien, Germany,, Frankfurt, Germany, 01.01.2003]

In: DECHEMA: DECHEMA-Statusseminar: Chiptechnologien, Germany,, 2003, Frankfurt

2002

Journal Articles

** Cserjan-Puschmann, M., Grabherr, R., Striedner, G., Clementschitsch, F., Bayer, K. Integrated systems approach for the optimization of microbial recombinant fermentation processes..

BioPharm, 15, 26-34 WoS

** Grabherr, R; Bayer, K; Impact of targeted vector design on Co/E1 plasmid replication..

Trends Biotechnol. 2002; 20(6):257-260 WoS PubMed

** Grabherr, R; Nilsson, E; Striedner, G; Bayer, K; Stabilizing plasmid copy number to improve recombinant protein production..

Biotechnol Bioeng. 2002; 77(2):142-147 WoS PubMed

** Ivansson D, Bayer K and Mandenius C-F. . Quantitation of intracellular recombinant human superoxide dismutase using surface plasmon resonance.

Analytica Chimica Acta , 456, 193-200 WoS

Patents

Bayer, K., Grabher, R., Nilsson, E. (2002): Expression vectors with modified ColE1 origin of replication for control of plasmid copy number.

, 2002-04-10; EP20000121709 200010

Conference & Workshop Proceedings, Paper, Abstract

Bayer K. (2002): Integrated Approach for Advanced Process Control and Monitoring of Recombinant Protein Production.
[M3c Conference, Lyngby, Denmark, 07.10.2002 - 08.10.2002]

In: EFB: M3c Conference, October 7th – 8th, 2002, Lyngby

H. Reischer, K. Dürrschmid, G. Striedner, F. Pötschacher, P. Etl, I. Schotola, K. Bayer (2002): Expression of green fluorescent protein (GFP) for the optimisation of recombinant fermentation processes.
[DECHEMA-Statusseminar: Chiptechnologien: Transkriptom - Proteom – Metabolom; Mikroarrays als universelles Werkzeug, Frankfurt am Main, Germany, 01.01.2002]

In: DECHEMA: DECHEMA-Statusseminar: Chiptechnologien: Transkriptom - Proteom – Metabolom; Mikroarrays als universelles Werkzeug, 2002, Frankfurt am Main, Germany

K. Dürrschmid, H. Reischer, W. Schmidt-Heck, J. Kern, F. Pötschacher, G. Striedner, R.Guthke and K. BayerMonitoring the dynamics of transcription and translation for the optimization of recombinant fermentation processes, Recombinant Protein Production II, Cernobbio, Como, Italien, 2002 (2002): Monitoring the dynamics of transcription and translation for the optimization of recombinant fermentation processes.
[Recombinant Protein Production II,, Cernobbio, Italy, 01.01.2002]

In: EFB: Recombinant Protein Production II,, 2002, Cernobbio, Como, Italien

Striedner G., Cserjan M., Pötschacher F., Bayer K. (2002): Tuning the transcription rate of recombinant protein in strong Eschericha coli expression systems through repressor titration.
[2nd International conference on Recombinant protein production 2002 - A comparative view on host physiology, Cernobbio, Italy, 14.11.2002 - 16.11.2002]

In: European Federation of Biotechnology: 2nd International conference on Recombinant protein production - A comparative view on host physiology, 14. - 16. November 2002, Cernobbio (Como) Italy; Abstract book EFB event #112, P61

W. Schmidt-Heck, H. Reischer, K. Dürrschmid and K. Bayer, R. Guthke (2002): A Novel Binary Clustering Algorithm to Analyze Gene Expression Time Series;.
[ECCB, Saarbrücken, Germany, 01.01.2002]

In: ECCB: ECCB, 2002, Saarbrücken

2001

Journal Articles

** Bachinger, Th., Mandenius, C.-F., Striedner, G., Clementschitsch, F., Dürrschmid, E., Cserjan-Puschmann, M., Doblhoff-Dier, O., Bayer, K. Non-invasive detection of the metabolic burden on recombinant microorganisms during fermentation processes..

Journal of Chemical Technology and Biotechnology, 76, 885-889 WoS

** Grabherr, R., Bayer, K. Vector Design Related to Bio-Processing..

Food Technol. Biotechnol., 39, 4, 265-269 WoS

Conference & Workshop Proceedings, Paper, Abstract

Bayer K. (2001): Integrated Systems Approach for the Optimization of Microbial Recombinant Fermentation Processes.
[221st National Spring Meeting of the American Chemical Society ACS 2001, San Diego, CA, USA, 01.04.2001 - 05.04.2001]

In: ACS: National Meeting - 221st ACS National Meeting, April 1-5, 2001, San Diego, CA

H. Reischer, K. Dürrschmid, G. Striedner, F. Pötschacher, P. Etl, I. Schotola and K. Bayer (2001): Optimisation of recombinant fermentations using DNA-micorarrays;.
[Joint Annual Meeting 2001: ÖGBM, ÖGGGT, ÖGBT, EMBnet,, Vienna, Austria, 01.01.2001]

In: ÖGBM, ÖGGGT, ÖGBT, EMBnet Abstract book p. 39: Joint Annual Meeting 2001: ÖGBM, ÖGGGT, ÖGBT, EMBnet,, 2001, Vienna

Striedner G., Pötschacher F., Reischer H., Dürrschmid K., Bayer K. (2001): Madrid, ; Appropriate induction - an efficient tool for optimisation, control and physiological investigations of recombinant E. coli processes..
[10th EUROPEAN CONGRESS ON BIOTECHNOLOGY, Madrid, Spain, 08.07.2001 - 11.07.2001]

In: European Federation of Biotechnology: 10th EUROPEAN CONGRESS ON BIOTECHNOLOGY, 8-11. July 2001, Madrid, Spain; Abstract book

Chapter in Collected Volumes

G. Striedner, M. Cserjan-Puschmann, R. Grabherr, F. Clementschitsch, E. Nilsson and K. Bayer (2001): Metabolic approaches for the optimisation of recombinant fermentation processes.

In: Otto-Wilhelm Merten (Editor), D. Mattanovich (Editor), C. Lang (Editor), G. Larsson (Editor), P. Neubauer (Editor), D. Porro (Editor), P. Postma (Editor), J. Teixeira de Mattos (Editor), J.A. Cole (Editor), Recombinant Protein Production with Prokaryotic and Eukaryotic Cells A Comparative View on Host Physiology, 179-188; Springer; ISBN 978-0-7923-7137-3

2000

Journal Articles

** Ertl, P; Unterladstaetter, B; Bayer, K; Mikkelsen, SR Ferricyanide reduction by Escherichia coli: kinetics, mechanism, and application to the optimization of recombinant fermentations..

Anal Chem. 2000; 72(20):4949-4956 WoS PubMed

1999

** Cserjan-Puschmann, M; Kramer, W; Duerrschmid, E; Striedner, G; Bayer, K; Metabolic approaches for the optimisation of recombinant fermentation processes..

Appl Microbiol Biotechnol. 1999; 53(1):43-50 WoS PubMed

** Hirn, R; Schuster, B; Sleytr, UB; Bayerl, TM The effect of S-layer protein adsorption and crystallization on the collective motion of a planar lipid bilayer studied by dynamic light scattering..

Biophys J. 1999; 77(4):2066-2074 WoS PubMed PUBMED Central FullText FullText_BOKU

** Mattanovich, D; Kramer, W; Lüttich, C; Weik, R; Bayer, K; Katinger, H; Rational design of an improved induction scheme for recombinant Escherichia coli..

Biotechnol Bioeng. 1999; 58(2-3):296-298 WoS PubMed

** Weik, R., Striedner, G., Francky, A., Raspor, P., Bayer, K., Mattanovich, D. Induction of oxidofermentative ethanol formation in recombinant cells of Saccharomyces cerevisiae yeast..

Food. Technol. Biotechnol., 37, 191-194 WoS

1998

** Borth, N; Mitterbauer, R; Mattanovich, D; Kramer, W; Bayer, K; Katinger, H; Flow cytometric analysis of bacterial physiology during induction of foreign protein synthesis in recombinant Escherichia coli cells..

Cytometry. 1998; 31(2):125-129 WoS PubMed

** Breuer, S; Marzban, G; Cserjan-Puschman, M; Dürrschmid, E; Bayer, K Off-line quantitative monitoring of plasmid copy number in bacterial fermentation by capillary electrophoresis..

Electrophoresis. 1998; 19(14):2474-2478 WoS PubMed FullText FullText_BOKU

** Weik, R; Francky, A; Striedner, G; Raspor, P; Bayer, K; Mattanovich, D Recombinant expression of alliin lyase from garlic (Allium sativum) in bacteria and yeasts..

Planta Med. 1998; 64(4):387-388 WoS PubMed

1996

** Kramer W., Elmecker G., Weik R., Mattanovich D., Bayer K. Kinetics studies for the optimization of recombinant protein formation.

Annals Of The New York Academy Of Sciences, 782, 323-333 WoS PubMed

** Mattanovich, D; Weik, R; Thim, S; Kramer, W; Bayer, K; Katinger, H Optimization of recombinant gene expression in Escherichia coli..

Ann N Y Acad Sci. 1996; 782(6):182-190 WoS PubMed

Conference & Workshop Proceedings, Paper, Abstract

Mattanovich, D., Kramer, W., Lüttich, Ch., Weik, R., Bayer, K., Katinger, H. (1996): Rational design of an improved induction scheme for recombinant Escherichia coli..

Engineering Foundation Conference 'rDNA Biotechnology IV Focus on Metabolic Engineering', 6.-11.10.1996, Danvers, MA, USA

Puschmann, M., Kramer, W., Dürrschmid, E., Bayer, K. (1996): Analyse von Nukleotiden zur Kontrolle rekombinanter Fermentationsprozesse..
[13. Forum Analytik 1996, Vienna, Austria, 22.01.1996 - 24.01.1996]

13. Forum Analytik 22.-24.1.1996, HP Zentrum Wien, Lebensmittel und Biotechnologie,13, p. 63

Weik, R., Striedner, G., Töllner, L., Francky, A., Raspor, P., Bayer, K., Mattanovich, D. (1996): Regulation of recombinant protein production in Saccharomyces cerevisiae by the ADH1 promoter..

3rd European Congress on Fungal Genetics, 27-30.3.1996, Münster, DE

Chapter in Collected Volumes

Doblhoff-Dier, O., Bayer, K. (1996): Computer controlled fermentation..

In: Doyle, A., Griffith, J. B.: Cell and tissue culture laboratory procedures. 28E3.1, Vol. 3, J. Wiley & Sons

1995

Conference & Workshop Proceedings, Paper, Abstract

Mikler, R., Kramer, W., Doblhoff-Dier, O., Bayer, K. (1995): Strategies for optimal dissolved oxygen control..

Proc. 6th International Conference on Computer Applications in Biotechnology, May 14-17, 1995, 315-318, Garmisch Partenkirchen

1994

Journal Articles

** Loibner, A. P., Doblhoff-Dier, O., Zach, N., Bayer, K., Katinger, H., Lobmaier, Ch., Schalkhammer, Th., Pittner, F. Automated glucose measurement with microstructured thin layer biosensors for the control of fermentation processes..

Sensors and Actuators B, 18/19, 603-606 WoS

Conference & Workshop Proceedings, Paper, Abstract

Loibner, A.P., Zach, N., Dobloff-Dier, O., Reiter, M., Bayer, K., Katinger, H.W.D. (1994): On-line glucose control of animal cell cultures in fluidized beds.
[12th ESACT-Meeting 1993. Animal Cell Technology: Products for today, Prospects for tomorrow, Würzburg, Germany, 17.05.1993 - 21.05.1993]

In: Spier, R.E., Griffiths, J.B., and Berthold, W., Butterworth-Heinemann: 12th ESACT Meeting 1993: ‘Animal Cell Technology: Products for today, Prospects for tomorrow’, 1994, Oxford, UK, 372-375

Chapter in Collected Volumes

Kramer, W., Mattanovich, D., Elmecker, G., Weik, R., Lüttich, Ch., Bayer, K., Katinger, H. (1994): Regulable expression systems for the optimisation of recombinant protein production in Escherichia coli..

In: Alberghina, L., Frontali, L., P. Sensi, P. (eds.): Progress in biotechnology 9. 827-830, Amsterdam: Elsevier

1993

Patents

Bayer, K., Katinger, H., Kramer, W., Lüttich, Ch., Mattanovich, D. (1993): Verfahren zur Expression von Genen unter Kontrolle des lac-Operators..

Österr. Patent Nr. AT 397 812 B

1990

Conference & Workshop Proceedings, Paper, Abstract

Doblhoff-Dier, O., Huss, S., Plail, R., Unterluggauer, F., Kramer, W., Taferner, N., Bayer, K., Katinger, H. (1990): Pilot plant production of recombinant proteins..

5th European Congress on Biotechnology, p. 179, Copenhagen, Munksgaard

Kramer, W., Doblhoff-Dier, O., Lettner, H. P., Pettauer, D., Taferner, N., Bayer, K., Katinger, H. (1990): Developement of a control strategy for production of recombinat proteins..

5th European Congress on Biotechnology, p. 345, Copenhagen, Munksgaard

1989

Journal Articles

** Doblhoff-Dier, O; Schwengler, P; Ehrenhuber, B; Kramer, W; Bayer, K; Jansky, H; Svasek, P; Kohl, F Online monitoring of NH4+ concentration with compensation of interfering ion species influenced by simultaneous determination of Na+ and K+ with modular microscale ion selective fluid membrane sensors..

Biotechnol Bioeng. 1989; 34(10):1326-1330 WoS PubMed FullText FullText_BOKU

1988

Conference & Workshop Proceedings, Paper, Abstract

Kramer, W., Doblhoff, O., Bayer, K. (1988): Kinetic studies of bacterial alpha amylase production..

4th Int. Workshop Microb. Physiol. and the Manufact. Industry, Hadjuszobozlo (Hungary)

1987

Journal Articles

* Doblhoff-Dier, O; Bayer, K; Katinger, HW; Jansky, H; Svasek, P; Paschke, F (1987): A modular microsensor for monitoring fermentation processes..

Dev Biol Stand. 1987; 66(2):345-348 PubMed

Conference & Workshop Proceedings, Paper, Abstract

Doblhoff-Dier, O., Bayer, K., Katinger, H. (1987): Einrichtung einer computergestützten Laboranlage zur Züchtung tierischer Zellen..

Informationsveranstaltung des Bundesministeriums f. Wiss. Forschung, Bad Ischl

Doblhoff-Dier, O., Bayer, K., Katinger, H., Kohl, F., Jansky, H., Svasek, P., Paschke, F. (1987): Modular Hard- and Software Concept for Labscale Computer Controlled Fermentation..

In: Neijssel, O. M., Meer, R. R. van der, Luyben, K. (eds.): Proceedings of the 4th European Congress on Biotechnology, Amsterdam: Elsevier

Chapter in Collected Volumes

Bayer, K. (1987): Bioprocess Control..

In: Knorr, D. (ed.): Food biotechnology. p. 233, New York and Basel: Marcel Dekker Inc

1985

Conference & Workshop Proceedings, Paper, Abstract

Doblhoff-Dier, O., Bayer, K., Svasek, P., Jansky, J. (1985): Modular and highly flexible measurement and control system for bioprocess developement..

1st IFAC Symposium on Modelling and Control of Biotechnolocal Processes

1984

Bayer, K., Doblhoff-Dier, O. (1984): Optimizing fungal amylase production in submerged culture..

3rd European Congress on Biotechnology, Munich 1984, Vol 1, 725-730, Verlag Chemie

1982

Journal Articles

** BAYER, K; MEISTER, G HYPERKINETIC NUTRIENT-UPTAKE BY CANDIDA-INTERMEDIA.

EUR J APPL MICROBIOL BIOTECH. 1982; 15(1): 36-40. WoS

1979

Chapter in Collected Volumes

Meyrath, J., Bayer, K. (1979): Biomass from whey..

In: Rose, A. H. (ed.): Economic microbiology. Vol. 4, London: Academic Press

1976

Conference & Workshop Proceedings, Paper, Abstract

Meyrath, J., Bayer, K., Braun, R., Zerlauth, G. (1976): Ausgewählte Mikroorganismen für die Veredlung organisch belasteter industrieller Abwässer..

141-153, Wien: Österr. Agrarverlag

Chapter in Collected Volumes

Meyrath, J., Bayer, K., Braun, R., Zerlauth, G. (1976): Ausgewählte Mikroorganismen für die Veredelung organisch belasteter industrieller Abwässer..

In: Franz, H. (Hrsg.): Umweltprobleme aus der Sicht der Bodenkultur. p. 141, Wien: Österr. Agrarverlag

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