Clemens Grünwald-Gruber
Dipl.-Ing. Dr.nat.techn. Clemens Grünwald-Gruber
Institut BOKU Core Facilities
Institut Institut für Biochemie (DCH/BC)
Standort Muthgasse 11, 1190 Wien
Email clemens.gruber@boku.ac.at
Tel: +43 1 47654-35052
Projekte
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Publikationen
Wissentransfer in die Gesellschaft
Medienbeiträge
Vorträge
(2019) Analysis of bacterial arabinosyl transferase reaction products of Kdo2-lipid A by LC-ESI-MS
Autoren: Grünwald-Gruber, C; Olagnon, C; Julia Monjaras, F; Kosma, P; Altmann F
APMRS 2019
(2019) Investigation of 4-amino-4-deoxy-L-arabinose transferases from Gram-negative bacteria involved in antibiotic resistance
Autoren: Olagnon, C; Feras, JM; Grünwald-Gruber, C; Altmann, F; Kerner, L; Valvano, MA, Kosma, P.
Eurocarb 20 2019
(2019) Subcellular proteome atlas of the yeast Komagataella phaffii
Autoren: Valli, M; Grillitsch, KH; Grünwald-Gruber, C; Tatto, NE; Hrobath, B; Klug, L; Ivashov, V; Hauzmayer, S; Koller, M; Leisch, F; Gasser, B; Graf AB; Altmann, F; Daum, G; Mattanovich D
PYFF7 2019
(2019) A conserved glycosyltransferase from the general protein O-glycosylation pathway of Bacteroidetes
Autoren: Braun*, M., B. Janesch, M. B. Tomek, D. Maresch, C. Grünwald-Gruber, M. Blaukopf, P. Kosma, F. Altmann, C. Schäffer
Soc. for Glycobiology Annual Meeting
(2019) Analysis of intracellular interaction partners of recombinant proteins in Pichia pastoris
Autoren: Schmelzer, B; Grünwald-Gruber, C; Altmann, F; Gasser, B; Mattanovich, D
RPP10 2019
(2018) Characterization of O-glycosylation in recombinant Pichia pastoris
Autoren: Radoman, B; Grünwald-Gruber, C; Rebnegger, C; Schmelzer, B; Altmann, F; Mattanovich, D; Gasser, B
EMBO Workshop - Enzymes, biocatalysis ans chemical biology: The new frontiers
(2018) Analysis of mouse brain N-glycans by (PGC-)LC-ESI-MS using isotopically labeled standards
Autoren: Grünwald-Gruber, C; Thader, A; Urteil, J; Maresch, D; Altmann, F;
22nd International Mass Spectrometry Conference IMSC 2018
(2018) Characterization of O-glycans in recombinant proteins produces in Pichia pastoris,
Autoren: Radoman, B; Grünwald-Gruber, C; Schmelzer, B; Gasser, B; Mattanovich, D; Altmann, F
EMBO Practical Course - Characterization of post translational modifications in cellular signaling
(2018) Multiplexed isotope labeled standards for isomeric analysis of N-glycans
Autoren: Maresch, D; Grünwald-Gruber, C; Thader, A; Altmann, F
22nd International Mass Spectrometry Conference IMSC 2018
(2017) Beyond the golden standard – N-glycan analysis with ultimate power of isomer discrimination and its application to biological questions.
Autoren: Altmann, F; Grünwald-Gruber, C; Maresch, D; Thader, A
14th Bratislava Symposium on Saccharides BSS 2017
(2017) Simultaneous identification and relative quantification of 16 putative allergens from tomato
Autoren: Mócsai, RT; Grünwald-Gruber, C; Milotay, P; Gasztonyi, M; Tömösközi-Farkas, R
19th EuroFoodChem Conference 2017
(2017) Determination of true ratios of different N-glycan structures in electrospray ionization-mass spectrometry
Autoren: Grünwald-Gruber, C: Thader, A; Maresch, D; Dalik, T; Altmann, F
Austrian Proteomics and Metabolomics Research Symposium APRS 2017
(2017) Identification of intracellular interaction partners of recombinant proteins
Autoren: Schmelzer, B; Grünwald-Gruber, C; Altmann, F; Gasser, B; Mattanovich, D;
European Summit of Industrial Biotechnology ESIB 2017
(2017) Characterizing Vacuolar Protein Sorting Pathways in the Yeast Pichia Pastoris
Autoren: Marsalek, L; Grünwald-Gruber, C; Altmann, F; Mattanovich, D; Puxbaum, V; Gasser, B;
European Summit of Industrial Biotechnology ESIB 2017
(2017) Determination of true ratios of different N-glycan structures in electrospray ionization-mass spectrometry
Autoren: Grünwald-Gruber, C; Thader, A; Maresch, D; Dalik, T; Altmann, F
28th MassSpec Forum Vienna 2017
(2017) Characterizing vacuolar protein sorting pathways in the yeast Pichia pastoris
Autoren: Gasser, B; Marsalek, L; Gruber, C; Altmann, F; Mattanovich, D; Puxbaum, V;
28th International Conference on Yeast Genetics and Molecular Biology ICYGMB 2017
(2017) Site-specific N-glycosylation analysis of human IgA isotypes produced in glyco-engineered plants by LC-ESI-MS
Autoren: Maresch, D; Göritzer, K; Grünwald-Gruber, C; Strasser, R; Altmann, F
16th Human Proteome Organization World Congress 2017
(2017) Portraying the sweet and the dark sides of a protein
Autoren: Grünwald-Gruber, C; Maresch, D; Altmann, F;
European Summit of Industrial Biotechnology ESIB 2017
(2017) Characterization of O-glycans in recombinant proteins produced in Pichia pastoris
Autoren: Radoman, B; Grünwald-Gruber, C; Schmelzer, B; Gasser, B; Altmann, F; Mattanovich, D;
9th International Conference on Recombinant Protein Production RPP9 2017
(2017) Characterization of O-glycans in recombinant proteins produced in Pichia pastoris
Autoren: Radoman, B; Grünwald-Gruber, C; Schmelzer, B; Gasser, B; Altmann, F; Mattanovich, D;
European Summit of Industrial Biotechnology ESIB 2017
(2017) Production of recombinant glycosylated polymeric IgM antibodies in CHO cells
Autoren: Hennicke, J; Grünwald-Gruber, C; Reinhart, D; Altmann, F; Kunert, R
GlycoBioTec 2017
(2017) Analysis of human brain N-glycans by (PGC-)LC-ESI-MS using isotopically labeled standards
Autoren: Grünwald-Gruber, C; Thader, A; Maresch, D; Hirtler, L; Altmann, F
16th Human Proteome Organization World Congress 2017
(2017) Identification of intracellular interaction partners of recombinant proteins
Autoren: Schmelzer, B; Grünwald-Gruber, C; Altmann, F; Gasser, B; Mattanovich, D;
9th International Conference on Recombinant Protein Production RPP9 2017
(2016) Identification of intracellular interaction partners of recombinant proteins
Autoren: Schmelzer, B; Grünwald-Gruber, C; Altmann, F; Gasser, B; Mattanovich, D;
ESIB – European Summit of Industrial Biotechnology
(2016) Systems-level organization of yeast methylotrophic lifestyle: The xylulose-monophosphate cycle of methanol assimilation utilizes a duplicated methanol inducible enzyme set and is entirely localized to peroxisomes
Autoren: Rußmayer, H; Buchetics, M; Gruber, C; Valli, M; Grillitsch, K; Modarres, G; Drexler, H; Steiger, M; Daum, G; Graf, A; Altmann, F; Hann, S; Sauer, M; Mattanovich, D; Gasser, B;
PYFF6 - 6th Conference on Physiology of Yeasts and Filamentous Fungi
(2016) Methanol metabolism revisited: The xylulose-monophosphate cycle of methanol assimilation utilizes a duplicated methanol inducible enzyme set and is entirely localized to peroxisomes
Autoren: Rußmayer, H; Buchetics, M; Gruber, C; Valli, M; Grillitsch, K; Modarres, G; Drexler, H; Steiger, M; Daum, G; Graf, A; Altmann, F; Hann, S; Sauer, M; Mattanovich, D; Gasser, B;
Pichia 2016
(2016) Dioxygen evolution by chlorite dismutase depends on co-ordination of transiently produced hypochlorite to an oxoiron(IV) intermediate
Autoren: Hofbauer, S., Grünwald-Gruber, C., Schaffner, I., Sündermann, A., Jakopitsch, C., Oostenbrink, C., Djinovic-Carugo, K., Furtmüller, P.G., Obinger, C.
79th Harden Conference on Oxygen Evolution and Reduction
(2016) Curation of the Pichia pastoris genome annotation by integration of RNA-Seq and proteomic data
Autoren: Valli, M; Peymann, A; Gruber, C; Tatto, N; Mattanovich, D; Gasser, B; Graf, A;
Pichia 2016
(2016) Secretome diversity of Pichia pastoris in the presence of different carbon sources
Autoren: Hohlweg, J; Gruber, C; Altmann, F; Valli, M; Mattanovich, D; Gasser, B;
ESIB 2016
(2016) Curation of the Pichia pastoris (Komagatella phaffi) genome annotation by integration of RNA-Seq and proteomic data
Autoren: Valli, M; Tatto, N; Peymann, A; Gruber, C; Landes, N; Ekker, H; Thallinger, G; Mattanovich, D; Gasser, B; Graf, A
ESIB 2016
(2016) Analysis of O-linked glycans of recombinant Art v 1 by LC-ESI-MS-ETD
Autoren: Grünwald-Gruber, C: Svehla, E; Windwarder, M; Thader, A; Maresch, D; Altmann, F
BSPR meeting 2016
(2015) Outer membrane vesicles of Tannerella forsythia: Biogenesis, composition, and virulence
Autoren: Friedrich, V., C. Gruber, I. Nimeth, S. Pabinger, F. Altmann, P. Messner, O. Andrukhov, C. Schäffer*
2nd International Conference on Porphyromonas gingivalis and Related Species in Oral and Systemic Diseases 2015
(2015) Secretome diversity of Pichia Pastoris in the presence of different carbon sources
Autoren: Hohlweg, J; Gruber, C; Altmann, F; Valli, M; Mattanovich, D; Gasser, B
27th International Conference on Yeast Genetics and Molecular Biology ICYGMB 2015
(2015) The Pichia pastoris secretome in fed-batch cultivations is carbon source independent
Autoren: Hohlweg, Jonas, Gruber, Clemens, Altmann, Friedrich, Valli, Minoska, Mattanovich, Diethard, Gasser, Brigitte
ACIB Science Days 2015
(2015) The xylulose-monophosphate cycle of methanol assimilation utilizes a duplicated methanol inducible enzyme set and is entirely localized to peroxisomes
Autoren: Gasser, B; Russmayer, H; Buchetics, M; Gruber, C; Valli, M; Grillitsch, K; Modarres, G; Drexler, H; Steiger, M; Daum, G; Graf, AB; Altmann, F; Hann, S; Sauer, M; Mattanovich, D
27th International Conference on Yeast Genetics and Molecular Biology ICYGMB 2015
(2014) Investigation of a prokaryotic peroxidase with a covalently bound heme b from the cyanobacterium Lyngbya sp PCC 8106
Autoren: Nicolussi, A; Auer, M; Schutz, G; Gruber, C; Pirker, K; Zamocky, M; Furtmuller, PG; Obinger, C
12th European Biological Inorganic Chemistry Conference EuroBIC 2014
(2014) Multistep processing of the secretion leader of the CRISP family member Epx1 in Pichia pastoris and implications on protein localization
Autoren: Heiss, Silvia; Puxbaum, Verena; Gruber, Clemens; Altmann, Friedrich; Mattanovich, Diethard and Gasser, Brigitte
ACIB-UAB Workshop - Systems Biology for Metabolic Engineering
(2014) Proteomic study of Pichia pastoris cell compartments
Autoren: Gruber, C; Grillitsch, K-H; Klug, L; Valli, M; Gasser, B; Mattanovich, D; Daum, G; Altmann, F
APRS 2014
(2014) Influence of recombinant protein expression on the proteome of Pichia pastoris
Autoren: Gruber, Clemens; Landes, Nils; Valli, Minoska; Modarres, Gerda; Gasser, Brigitte; Graf, Alexandra; Altmann, Friedrich; Mattanovich, Diethard
6th ÖGMBT Annual Meeting 2014 - Life Sciences meet Entrepreneurship
(2014) Proteomic study of Pichia pastoris cell compartments
Autoren: Gruber, C; Landes, N; Valli, M; Modarres, G; Gasser, B; Graf, AB; Altmann, F; Mattanovich, D
6th ÖGMBT Annual Meeting 2014 - Life Sciences meet Entrepreneurship
(2014) Methanol induced changes on the transcriptome, proteome, metabolome and fluxome of Pichia pastoris
Autoren: Rußmayer, Hannes; Buchetics, Markus; Graf, Alexandra; Valli, Minoska; Gruber, Clemens; Modarres, Gerda; Altmann, Friedrich; Guerrasio, Raffaelle; Klavins, Kristaps; Neubauer, Stefan; Steiger, Matthias; Chalabi, Ali Al; Krebiehl, Guido; Sonntag, Denise; Haberhauer-Troyer, Christina; Köllensperger, Gunda; Hann, Stephan; Sauer, Michael; Gasser, Brigitte; Mattanovich, Diethard
ACIB-UAB Workshop - Systems Biology for Metabolic Engineering
(2014) Methanol induced changes on the transcriptome, proteome, metabolome and fluxome of Pichia pastoris
Autoren: Rußmayer, Hannes; Buchetics, Markus; Graf, Alexandra; Valli, Minoska; Gruber, Clemens; Modarres, Gerda; Altmann, Friedrich; Guerrasio, Raffaelle; Klavins, Kristaps; Neubauer, Stefan; Steiger, Matthias; Chalabi, Ali Al; Krebiehl, Guido; Sonntag, Denise; Haberhauer-Troyer, Christina; Köllensperger, Gunda; Hann, Steph
ACIB-UAB Workshop - Systems Biology for Metabolic Engineering
(2014) Understanding the inhibition mechanism of chlorite dismutase from the nitrite-oxidizing bacterium Candidatus Nitrospira defluvii
Autoren: Hofbauer, S; Gruber, C; Schaffner, I; Pirker, KF; Jakopitsch, C; Sundermann, A; Oostenbrink, C; Furtmuller, PG; Obinger, C
12th European Biological Inorganic Chemistry Conference EuroBIC 2014
(2014) Multistep processing of the secretion leader of the CRISP family member Epx1 in Pichia pastoris and implications on protein localization
Autoren: Heiss, Silvia; Puxbaum, Verena; Gruber, Clemens; Altmann, Friedrich; Mattanovich, Diethard and Gasser, Brigitte
EMBO Workshop Protein and lipid function in secretion and endocytosis
(2014) Cross-species comparison of recombinant protein secretion in CHO cells and Pichia pastoris
Autoren: Landes, Nils; Maccani, Andreas; Leitner, Christian; Maurer, Michael; Graf, Alexandra; Valli, Minoska; Gruber, Clemens; Modarres, Gerda; Altmann, Friedrich; Gasser, Brigitte; Ernst, Wolfgang; Kunert, Renate; Mattanovich, Diethard
ECB16 2014
(2013) Understanding highly stable chlorite dismutase form nitrate-oxidizing bacterium Candidatus “Nitrospira defluvii”
Autoren: Hofbauer, S., Gruber, C., Pirker, K. F., Schaffner, I., Hagmüller, A., Gysel, K., Mlynek, G., Kostan, J., Bellei, M., Daims, H., Djinovic-Carugo, K. Battistuzzi, G., Furtmüller, P.G. and Obinger, C
International Conference on Bioinorganic Chemistry ICBIC-16 2013
(2013) New highly stable chlorinating bacterial peroxidase with autocatalytically formed covalent heme to protein bonds
Autoren: Furtmuller, PG; Auer, M; Gruber, C; Pirker, K; Krioss, D; Hofbauer, S; Soudi, M; Obinger, C; Zamocky, M; Bellei, M; Battistuzzi, G
International Conference on Bioinorganic Chemistry ICBIC-16 2013
(2013) Multistep processing of the secretion leader of the CRISP family member Epx1 in Pichia pastoris and implications on protein localization
Autoren: Gasser, B; Heiss, S; Puxbaum, V; Gruber, C; Altmann, F; Mattanovich, D
26th International Conference on Yeast Genetics and Molecular Biology 2013
(2013) Understanding Chlorite Dismutase from Candidatus Nitrospira defluvii
Autoren: Hofbauer, S; Gruber, C; Pirker, KF; Schaffner, I; Furtmuller, PG; Obinger, C; Hagmuller, A; Gysel, K; Mlynek, G; Kostan, J; Djinovic-Carugo, K; Bellei, M; Battistuzzi, G; Daims, H
International Conference on Bioinorganic Chemistry ICBIC-16 2013
(2013) New highly stable chlorinating bacterial peroxidase with autocatalytically formed covalent heme to protein bonds
Autoren: Auer, M. Gruber, C. Bellei, M., Pirker, K., Kroiß, D., Zamocky, M. Teufer, A. S., Soudi, M., Battistuzzi, G., Obinger, C. and Furtmüller P. G.
International Conference on Bioinorganic Chemistry ICBIC-16 2013
(2013) Influence of carbon source on the Pichia pastoris proteome
Autoren: C. Gruber1)2), M. Buchetics1)3), G. Modarres1)3),B. Gasser1)3), A.B.Graf1)4), F. Altmann1)2)and D. Mattanovich1)3) Gruber, C; Buchetics, M; Modarres, G; Gasser, B; Graf, AB; Altmann, F; Mattanovich, M
11th Austrian Proteomic Research Symposium
(2012) Bacterial heme enzyme of high structural and funtional homology with mammaian peroxidases -characterization of the first representative of a new protein family
Autoren: Auer, M. Kroiß, D. Gruber, C. Zamocky, M. Furtmüller, P.G. & Obinger, C.
OxiZymes 2012
(2012) Human cathepsin O: glycosylation, processing and cellular activity
Autoren: Aufy, M; Porodko, A; Stadlmann, J; Gruber, C; Mach, L
13th International Symposium on Proteinases, Inhibitors and Biological Control 2012
CRISPR-based targeted epigenetic glyco-engineering in CHO cell
Autoren: Marx, N, Grünwald-Gruber, C; Dhiman, H; Nguyen Ngoc, L; Bydlinski, N; Hernandez Lopez, I; Klanert, G; Borth, N
First crystal structure of eosinophil peroxidase reveals suptile distinctions in the active site architecture and processing
Autoren: Pfanzagl, V; Leitgeb, U; Grünwald-Gruber, C; Furtmüller, P.G; Obinger, C;
Mechanism of inhibition of chlorite dismutase
Autoren: Hofbauer, S., Schaffner, I., Gruber, C., Pirker, K.F., Jakopitsch, C., Sündermann, A., Oostenbrink, C., Furtmüller, P.G., Obinger, C.
The role of the covalent heme to protein bond in the formation and reactivity of redox intermediates of a bacterial peroxidase with high homology to human peroxidases
Autoren: Auer, M., Nicolussi, A., Schütz, G. Gruber, C., Bellei, M., Battistuzzi, G., Furtmüller, P.G., Obinger, C
Characterizing vacuolar protein sorting pathways in the yeast Pichia pastoris
Autoren: Marsalek, L; Gruber, C; Altmann, F; Mattanovich, D; Puxbaum, V; Gasser, B;
Engineering vacuolar sorting pathways for efficient secretion of recombinant proteins
Autoren: Marsalek, L; Gruber, C; Altmann, F; Mattanovich, D; Puxbaum, V; Gasser, B;
Characterizing vacuolar protein sorting pathways for enhanced protein secretion in the yeast Pichia pastoris (Komagatella spp)
Autoren: Marsalek, L; Puxbaum, V; Gruber-Grünwald, C; Altmann, F; Mattanovich, D; Gasser, B