Marcus Weinguny

Publikationen

Es wurden 9 Publikationen gefunden.

• How to train your cell - Towards controlling phenotypes by harnessing the epigenome of Chinese hamster ovary production cell lines.

  quelle: Marx N, Eisenhut P, Weinguny M, Klanert G, Borth N. How to train your cell - Towards controlling phenotypes by harnessing the epigenome of Chinese hamster ovary production cell lines. Biotechnology Advances. 2022;56:107924. doi:https://doi.org/10.1016/j.biotechadv.2022.107924

  Originalbeitrag in Fachzeitschrift

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• Inclusion of maintenance energy improves the intracellular flux predictions of CHO

  quelle: Szeliova D, Stor J, Thiel I, Weinguny M, Hanscho M, Lhota G, et al. Inclusion of maintenance energy improves the intracellular flux predictions of CHO. PLoS Computational Biology. 2021;17(6). doi:https://doi.org/10.1371/journal.pcbi.1009022

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• Subcloning induces changes in the DNA-methylation pattern of outgrowing Chinese hamster ovary cell colonies

  quelle: Weinguny M, Klanert G, Eisenhut P, Lee I, Timp W, Borth N. Subcloning induces changes in the DNA-methylation pattern of outgrowing Chinese hamster ovary cell colonies. Biotechnology Journal. 2021;16(6). doi:https://doi.org/10.1002/biot.202000350

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• Directed evolution approach to enhance efficiency and speed of outgrowth during single cell subcloning of Chinese Hamster Ovary cells

  quelle: Weinguny M, Klanert G, Eisenhut P, Jonsson A, Ivansson D, Lovgren A, et al. Directed evolution approach to enhance efficiency and speed of outgrowth during single cell subcloning of Chinese Hamster Ovary cells. Computational and Structural Biotechnology Journal. 2020;18:1320-9. doi:https://doi.org/10.1016/j.csbj.2020.05.020

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• Random epigenetic modulation of CHO cells by repeated knockdown of DNA methyltransferases increases population diversity and enables sorting of cells with higher production capacities

  quelle: Weinguny M, Eisenhut P, Klanert G, Virgolini N, Marx N, Jonsson A, et al. Random epigenetic modulation of CHO cells by repeated knockdown of DNA methyltransferases increases population diversity and enables sorting of cells with higher production capacities. Biotechnology and Bioengineering. 2020;117(11):3435-47. doi:https://doi.org/10.1002/bit.27493

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• Systematic use of synthetic 5 '-UTR RNA structures to tune protein translation improves yield and quality of complex proteins in mammalian cell factories

  quelle: Eisenhut P, Mebrahtu A, Barzadd M, Thalen N, Klanert G, Weinguny M, et al. Systematic use of synthetic 5 ’-UTR RNA structures to tune protein translation improves yield and quality of complex proteins in mammalian cell factories. Nucleic Acids Research. 2020;48(20). doi:https://doi.org/10.1093/nar/gkaa847

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• A CRISPR/Cas9 based engineering strategy for overexpression of multiple genes in Chinese hamster ovary cells

  quelle: Eisenhut P, Klanert G, Weinguny M, Baier L, Jadhav V, Ivansson D, et al. A CRISPR/Cas9 based engineering strategy for overexpression of multiple genes in Chinese hamster ovary cells. Metabolic Engineering. 2018;48:72-81. doi:https://doi.org/10.1016/j.ymben.2018.05.017

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• A CRISPR/Cas9 based engineering strategy for overexpression of multiple genes in Chinese hamster ovary cells

  quelle: Eisenhut P, Klanert G, Weinguny M, Baier L, Jadhav V, Ivansson D, et al. A CRISPR/Cas9 based engineering strategy for overexpression of multiple genes in Chinese hamster ovary cells. New Biotechnology. 2018;44:145-. doi:https://doi.org/10.1016/j.nbt.2018.05.1123

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• Identifying new engineering targets in Chinese hamster ovary cells

  quelle: Klanert C, Daniel F, Weinguny M, Eisenhut P, Bhler E, Melcher M, et al. Identifying new engineering targets in Chinese hamster ovary cells. New Biotechnology. 2018;44:145-. doi:https://doi.org/10.1016/j.nbt.2018.05.1122

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