Brigitte Gasser
Assoc. Prof. Priv.-Doz. Dipl.-Ing. Dr.nat.techn. Brigitte Gasser
Institut Institut für Mikrobiologie und Mikrobielle Biotechnologie
Standort Muthgasse 18, 1190 Wien
Email brigitte.gasser@boku.ac.at
Tel: +43 1 47654-79033
ORCID: 0000-0003-2881-6370
AAD-8172-2020: ResearcherId
7004537519: AuthorId
Laufbahn
- 2019 Group Leader "Yeast Molecular Biotechnology"
- 2017 Associate Professor für Mikrobielle Systembiotechnologie
- 2017 Leiterin des CD-Labors für wachstumsentkoppelte Proteinproduktion in Hefe
- 2015 Co-Arbeitsgruppenleitung Mikrobielle Biotechnologie
- 2013 Habilitation in Molekulare Biotechnologie
- 2011 Key Researcher im Austrian Centre of Industrial Biotechnology
- 2009 Senior Scientist - Department of Biotechnology
- 2007 Promotion, Universität für Bodenkultur, Wien
- 2005 Forschungsaufenthalt am VTT Biotechnologie, Espoo, Finnland
- 2004 Universitätsassistentin
- 2003 Sponsion zum Dipl. Ing. der Lebensmittel- und Biotechnologie, Universität für Bodenkultur, Wien
- 2001 - 2002 SOCRATES Auslandssemester an der Universität von Reading, Großbritannien
Auszeichnungen
- 2022 FEMS Yeast Research - Best article of 2021 award
- 2019 Award for BOKU Innovation of the Year for „Carbon dioxide fixation with Pichia pastoris“ (together with co-inventors)
- 2019 BOKU Innovator of the Year
- 2019 Special Award at "S&B Awards" of the Rudolf Sallinger Funds for the CarboFeed project team
- 2015 Kardinal Innitzer Förderungspreis
- 2013 Professor Anton Kurir Foundation Award
- 2012 Science2Business Award (ACIB Projekt Pichia Cell Factory)
- 2011 Dr. Wolfgang Houska Award, B&C Private Foundation (2. Platz; together with colleagues)
- 2010 Poster Award - Conference on Physiology of Yeast and Filamentous Fungi PYFF4
- 2008 Poster Award - Conference on Recombinant Protein Production RPP5 (together with colleagues)
- 2007 Dissertationspreis der Österreichischen Gesellschaft für Biotechnologie (ÖGBT)
- 2007 Nominierung für den Austrian Life Science Award (ALSA07, 2. Preis)
Projekte
Es wurden 0 Projekte gefunden.
Publikationen
Wissentransfer in die Gesellschaft
Medienbeiträge
Vorträge
(2023) Uncovering near-zero growth associated long non-coding RNAs in Komagatella phaffii
Autoren: Coltman, B; Rebnegger, C; Gasser, B
Recombinant Protein Production, RPP11
(2023) Uncovering near-zero growth associated long non-coding RNAs in Komagatella phaffii
Autoren: Coltman, B; Rebnegger, C; Gasser, B
ICYGMB31 - YEAST 2023
(2023) Towards near-zero growth production ? Implications for strain and bioprocess design
Autoren: Gasser, B
CDG Forum
(2023) In vivo monitoring of reactive oxygen species in the yeast Komagataella phaffii using a genetically encoded fluorescent H2O2 biosensor
Autoren: Honorato, VM; Molin, M; Gasser, B
YEAST 2023
(2023) Increasing global translation activity and its impact on Komagataella phaffii
Autoren: Staudacher, J; Rebnegger, C; Mattanovich, D; Gasser B
YEAST 2023
(2023) Protein production dynamics and physiological adaptation of recombinant Komagataella phaffii at near-zero growth rates
Autoren: Rebnegger, C; Kowarz, V; Coltman, B; Mattanovich, D; Gasser, B
PYFF 8
(2023) Characterising an orthogonal thiamine-responsive riboswitch for expression control in the yeast Komagataella phaffii
Autoren: Malecki, P; Rebnegger, C; Gasser B
YEAST 2023
(2023) Pushing and pulling proteins into the yeast secretory pathway enhances recombinant protein secretion
Autoren: Zahrl, RJ; Prielhofer, R; Ata, Ö; Baumann, K; Burgard, J; Mattanovich, D; Gasser B
YEAST 2023, ICYGMB31
(2023) Characterising an orthogonal thiamine-responsive riboswitch for expression control in the yeast Komagataella phaffii
Autoren: Malecki, P; Rebnegger, C; Gasser, B
PYFF 8
(2023) Improving Lonza’s XS® Pichia production platform by systemic engineering
Autoren: Adelanto, N; Staudacher, J; Rebnegger, C; Kiziak, Ch; Chang, Y; Gasser, B; Mattanovich, D
RPP 11
(2023) Going beyond the limit: impact of increasing global translation activity on the productivity of recombinant secreted proteins in Pichia pastoris
Autoren: Staudacher, J; Rebnegger, C; Mattanovich, D; Gasser, B
RPP 11
(2023) Going beyond the limit: tuning global transcription and translation activity increases recombinant protein secretion in Komagataella phaffii
Autoren: Gasser, B; Staudacher, J; Rebnegger, C; Mattanovich, D
PYFF 8
(2023) Cell engineering and stress: Impact of increasing global translation activity on the Pichia pastoris transcriptome and proteome
Autoren: Staudacher, J; Rebnegger, C; Mattanovich, D; Gasser, B
Microbial Stress 2023
(2023) Gasser, B
Autoren: Pushing and pulling proteins into the yeast secretory pathway enhances recombinant protein secretion
YEAST 2023
(2022) Maintenance energy requirements determine metabolic rewiring of Komagataella phaffii at glucose-limited near-zero growth conditions
Autoren: Coltman, B; Rebnegger, C; Gasser, B; Zanghellini, J
14th Annual Meeting ÖGMBT 2022 - Life Sciences - now more than ever
(2022) Unfolded protein response biosensors for recombinant protein expression
Autoren: Godon, H; Puricellici, M; De, S; Adelantado, N; Kiziak, C; Gasser, B; Mattanovich, D
2nd Microbial Engineering ECI 2022
(2022) Going beyond the limit: impact of increasing global translation activity on the productivity of recombinant secreted proteins in Pichia pastoris
Autoren: Staudacher, J; Rebnegger, C; Mattanovich, D; Gasser, B
2nd Microbial Engineering ECI 2022
(2022) Pichia production platform engineering by systemic changes
Autoren: Kiziak, C; Adelantado, N; Staudacher, J; Rebnegger, C; Gasser, B; Mattanovich, D
2nd Microbial Engineering ECI 2022
(2022) Maintenance energy requirements determine metabolic rewiring of Komagataella phaffii at glucose-limited near-zero growth conditions
Autoren: Coltman, B; Rebnegger, C; Gasser, B; Zanghellini, J
36th International Specialised Symposium on Yeasts ISSY 2022
(2022) Flo8 – A versatile regulator for improving recombinant protein production in Pichia pastoris
Autoren: Rebnegger, C; Kowarz, V; Flores, M; Mattanovich, D; Gasser, B
2nd Microbial Engineering ECI 2022
(2022) Boosting transformation efficiency of Pichia pastoris
Autoren: Hussein, M; Mattanovich, D; Gasser, B
European Summit of Industrial Biotechnology ESIB & Pichia & 11th International Conference on Fiber & Polymer Biotechnology IFPB 2022
(2022) In pursuit of an orthogonal molecular switch for Komagataella phaffii
Autoren: Malecki, P; Rebnegger, C; Gasser, B
6th Applied Synthetic Biology in Europe ASBE 2022
(2022) Impact of oxygen availability on organelle-specific redox potentials and stress in recombinant protein producing Pichia pastoris
Autoren: Kostopoulou, A; Rebnegger, C; Gasser, B; Mattanovich, D
2nd Microbial Engineering ECI 2022
(2022) Investigating the role of oxidative stress response genes in protein secretion using a novel combinatorial Golden Gate based approach
Autoren: Mendes Honorato, V; Staudacher, J; Prielhofer, R; Gasser, B
2nd Microbial Engineering ECI 2022
(2022) Going beyond the limit: Increasing global translation activity leads to increased productivity of recombinant secreted proteins in Pichia pastoris
Autoren: Staudacher, J; Rebnegger, C; Mattanovich, D; Gasser, B
European Summit of Industrial Biotechnology ESIB & Pichia & 11th International Conference on Fiber & Polymer Biotechnology IFPB 2022
(2022) Flo8 – A versatile regulator for improving recombinant protein production in Pichia pastoris
Autoren: Rebnegger, C; Kowarz, V; Flores, M; Mattanovich, D; Gasser, B
European Summit of Industrial Biotechnology ESIB & Pichia & 11th International Conference on Fiber & Polymer Biotechnology IFPB 2022
(2022) In pursuit of an orthogonal molecular switch for Komagataella phaffii
Autoren: Małecki, P; Rebnegger, C; Gasser; B
14th Annual Meeting ÖGMBT 2022 - Life Sciences - now more than ever
(2022) Maintenance energy requirements determine metabolic rewiring of Komagataella phaffii at glucose-limited near-zero growth conditions
Autoren: Coltman, B; Rebnegger, C, Zanghellini, J, Gasser, B
European Summit of Industrial Biotechnology ESIB & Pichia & 11th International Conference on Fiber & Polymer Biotechnology IFPB 2022
(2022) Going beyond the limit: tuning global transcription and translation activity increases recombinant protein secretion in Pichia pastoris
Autoren: Gasser, B
BPI Europe 2019
(2022) Dynamic mathematical modelling of fed-batch cultivation to maximize recombinant protein production by Komagataella phaffii
Autoren: John Muthuraj, SMP; Gasser, B
European Summit of Industrial Biotechnology ESIB & Pichia & 11th International Conference on Fiber & Polymer Biotechnology IFPB 2022
(2022) Super-fast oxidases and more: novel yeast enzymes and mechanisms of oxidative protein folding
Autoren: Palma, A; Ruddock, L; Gasser, B
European Summit of Industrial Biotechnology ESIB & Pichia & 11th International Conference on Fiber & Polymer Biotechnology IFPB 2022
(2022) In pursuit of an orthogonal molecular switch for Komagataella phfaffii
Autoren: Malecki, P; Rebnegger, C; Gasser, B
14th Annual Meeting ÖGMBT 2022 - Life Sciences - now more than ever
(2022) Unfolded protein response biosensors for recombinant protein production
Autoren: Godon, H; Puricelli, M; De, S; Adelantado, N; Kiziak, C; Gasser, B; Mattanovich, D
14th Annual Meeting ÖGMBT 2022 - Life Sciences - now more than ever
(2022) Unfolded protein response biosensors for recombinant protein expression
Autoren: Godon, H; Puricelli, S; De, S; Adalanto, C; Kiziak, C; Gasser, B; Mattanovich, D
European Summit of Industrial Biotechnology ESIB & Pichia & 11th International Conference on Fiber & Polymer Biotechnology IFPB 2022
(2022) Maintenance energy requirement largely determines metabolic rewiring of Komagataella phaffii at glucose limited near zero growth
Autoren: Coltman, B; Rebnegger, C; Gasser, B; Zanghellini, J
6th Applied Synthetic Biology in Europe ASBE 2022
(2022) Pichia production host engineering by systemic host changes
Autoren: Kiziak, C; Adelanto, N; Staudacher, J; Rebnegger, C; Gassser, B; Mattanovich, D
European Summit of Industrial Biotechnology ESIB & Pichia & 11th International Conference on Fiber & Polymer Biotechnology IFPB 2022
(2022) Strategies to improve yeast-based production of antibody molecules
Autoren: Gasser, B
3R Online Seminar Series
(2022) Impact of oxygen availability on organelle-specific redox potentials and stress in recombinant protein producing Pichia pastoris
Autoren: Kostopoulou, A; Rebnegger, C; Gasser, B; Mattanovich, D
European Summit of Industrial Biotechnology ESIB & Pichia & 11th International Conference on Fiber & Polymer Biotechnology IFPB 2022
(2022) Protein production dynamics and pyhsiological adaptation of recombinant Pichia pastoris at near-zero growth rates
Autoren: Rebnegger, C; Kowarz, V; Coltman, B; Mattanovich, D; Gasser, B
European Summit of Industrial Biotechnology ESIB & Pichia & 11th International Conference on Fiber & Polymer Biotechnology IFPB 2022
(2022) Lebende Proteinfabriken: von der Zelle zum Produkt
Autoren: Gasser, B
Töchtertag 2022
(2021) Redox balancing in recombinant protein-producing Pichia pastoris with altered protein folding
Autoren: Palma, A; Ruddock, L; Mattanovich, D; Gasser, B
ICY15 meets ICYGMB30
(2021) Assessing flux rearrangements of an alternate methanol metabolism that enables efficient recombinant protein production in Pichia pastoris
Autoren: Coltman, B; Zavec, D; Mattanovich, D; Gasser, B; Zanghellini, J
ICY15 meets ICYGMB30
(2021) Engineering the glucose responsive promoter PG1
Autoren: Flores Villegas, MC; Rebnegger, C; Kowarz, V; Kiziak, C; Mattanovich, D; Gasser, B
ICY15 meets ICYGMB30
(2021) Investigating the role of oxidative stress response genes in protein secretion using a novel Golden PiCS-based approach.
Autoren: Mendes Honorato, V; Staudacher, J; Gasser B.
Pichia 2021
(2021) Flo8 – a versatile regulator for improving recombinant protein production in Pichia pastoris
Autoren: Rebnegger, C; Kowarz, V; Flores Villegas, M; Mattanovich, D; Gasser, B
ICY15 meets ICYGMB30
(2021) Treatment with surfactants enables quantification of translational activity by O-propargyl-puromycin labelling in P. pastoris.
Autoren: Staudacher, J; Rebnegger, C; Gasser, B
Pichia 2021 Conference
(2021) Treatment with surfactants enables quantification of translational activity by O-propargyl-puromycin labelling in P. pastoris.
Autoren: Staudacher, J; Rebnegger, C; Gasser, B
15th International Congress on Yeast / 30th Int. Conference on Yeast Genetics and Molecular Biology (ICY15 meets ICYGMB30)
(2021) Assessing flux rearrangements of an alternate methanol metabolism that enables efficient recombinant protein production in Pichia pastoris
Autoren: Coltman, B; Zavec, D; Mattanovich, D; Gasser, B; Zanghellini, J
7th Conference on Constraint-Based Reconstruction and Analysis COBRA 2021
(2021) Going beyond the limit: impact of increasing global translation activity on the productivity of recombinant secreted proteins in Pichia pastoris.
Autoren: Staudacher, J; Rebnegger, C; Mattanovich, D; Gasser, B
15th International Congress on Yeast / 30th Int. Conference on Yeast Genetics and Molecular Biology (ICY15 meets ICYGMB30)
(2021) Impact of cultivation conditions on organelle-specific redox potentials and stress in recombinant protein producing Pichia pastoris
Autoren: Kostopoulou, A; Rebnegger, C; Gasser, B; Mattanovich, D
ICY15 meets ICYGMB30
(2021) A synthetic Calvin cycle enables autotrophic growth in Pichia pastoris
Autoren: Gaßler, T; Baumschabl, M; Egermeier, M; Gasser, B; Sauer, M; Steiger, M; Mattanovich, D
ICY15 meets ICYGMB30
(2021) Investigating the role of oxidative stress response genes in protein secretion using a novel Golden PiCS-based approach
Autoren: Mendes Honorato, V; Staudacher, J; Gasser B
ICY15 meets ICYGMB30
(2020) Redox balancing in recombinant protein-producing Pichia pastoris with altered protein folding
Autoren: Palma, A; Zavec, D; Mattanovich, D; Gasser, B.
5th Applied Synthetic Biology in Europe 2020
(2020) A synthetic Calvin cycle enables autotrophic growth in yeast
Autoren: Gassler, T; Egermeier, M; Gasser, B; Sauer, M; Steiger, MG; Mattanovich, D
5th Applied Synthetic Biology Conference in Europe 2020
(2019) Subcellular proteome atlas of the yeast Komagataella phaffii
Autoren: Valli, M; Grillitsch, KH; Grünwald-Gruber, C; Tatto, NE; Hrobath, B; Klug, L; Ivashov, V; Hauzmayer, S; Koller, M; Leisch, F; Gasser, B; Graf AB; Altmann, F; Daum, G; Mattanovich D
PYFF7 2019
(2019) Slow growth rate triggered transition to pseudohyphal phenotype of the protein production host Pichia pastoris
Autoren: De, S; Buchetics M; Rebnegger, C; Mattanovich, D; Gasser, B
RPP10 2019
(2019) XS™ Pichia 2.0: closing the gap between bacterial and mammalian systems for the production of recombinant proteins
Autoren: Adelantado, N; Claes, K; Reichinger, M; Wagner, N; Prielhofer, R; Gasser, B; Mattanovich, D; Kiziak, Ch
RPP10 2019
(2019) Protein production dynamics and physiological adaptiation of recombinant Pichia pastoris at near-zero growth rates
Autoren: Rebnegger, C; Kowarz, V; Mattanovich, D; Gasser, B
PYFF7 2019
(2019) A synthetic yeast for efficient assimilation of carbon dioxide
Autoren: Gassler, T; Gasser, B; Sauer, M; Steiger, M; Mattanovich D
47th Annual Conference on Yeasts 2019
(2019) Introduction of unnatural amino acids in recombinant proteins with the yeast Pichia pastoris
Autoren: Tir, N;Heistinger, L; Gasser, B; Mattanovich, D
26 HSKIKI - 26th Croatian Meeting of Chemists and Chemical Engineers
(2019) Metabolic response to model-based engineering of NADPH supply in Pichia pastoris
Autoren: Peña, D; Haltrich, D; Mattanovich, D; Zanghellini J; Gasser, B
RPP10 2019
(2019) Introduction of unnatural amino acids in recombinant proteins with the yeast Pichia pastoris
Autoren: Tir, N; Heistinger, L; Gasser, B; Mattanovich, D
RPP10 2019
(2019) A synthetic yeast for efficient assimilation of carbon dioxide
Autoren: Gassler T; Gasser B; Sauer M; Steiger MG; Mattanovich D
46th Annual Conference on Yeasts 2019
(2019) Slow Growth Rate triggered transition to a pseudohyphal lifestyle of the protein production host Pichia pastoris
Autoren: De, S; Buchetics, M; Rebnegger, C; Mattanovich, D; Gasser, B
BME 2019
(2019) Population heterogenity of the Komagataella phaffii mating response
Autoren: Heistinger, L; Gasser, B; Mattanovich, D
PYFF7 2019
(2019) Analysis of intracellular interaction partners of recombinant proteins in Pichia pastoris
Autoren: Schmelzer, B; Grünwald-Gruber, C; Altmann, F; Gasser, B; Mattanovich, D
RPP10 2019
(2019) Towards establishing a method to measure translation in Pichia pastoris
Autoren: Staudacher, J; Gasser, B
RPP10 2019
(2019) Synthetic biology for efficient assimilation of carbon dioxide
Autoren: Gassler T; Gasser B; Sauer M; Steiger MG; Mattanovich D
14th Asian Congress on Biotechnology ACB 2019
(2019) Characterization of O-glycans in recombinant proteins produced in Pichia pastoris
Autoren: Radoman, B; Grünwald-Gruber, C; Gasser, B; Altmann, F; Mattanovich D;
RNA Editing Gordon Research Conference (GRC) 2019
(2019) Characterization of transcription factors in Pichia pastoris
Autoren: Flores Villegas, M; Mattanovich, D; Gasser, B
RPP10 2019
(2019) Towards establishing a method to measure translation in Pichia pastoris
Autoren: Staudacher, J; Gasser, B;
29 Int. Conference on Yeast Genetics and Molecular Biology
(2018) A Synthetic Yeast for Efficient Assimilation of Carbon Dioxide.
Autoren: Gaßler, Thomas; Gasser, Brigitte; Sauer, Michael; Matthias G. Steiger; Mattanovich, D
12th Metabolic Engineering 2018
(2018) A synthetic yeast for efficient assimilation of carbon dioxide
Autoren: Gassler T; Gasser B; Sauer M; Steiger M; Mattanovich D
Advances in Microbiology and Biotechnology 2018
(2018) Production under the AOX1 promoter in methanol utilization negative Pichia pastoris: an efficient expression system for less intensive fermentation
Autoren: Zavec, D; Gasser, B; Mattanovich, D
ISSY34 2018
(2018) Dissection of growth-rate- and cell-cycle-dependent gene regulation in Pichia pastoris
Autoren: Rebnegger, C; Burgard, J; Graf, AB; Maurer, M; Gasser, B; Mattanovich, D;
ECB 2018
(2018) Industrial yeast strain efficiently assimilating carbon dioxide
Autoren: Steiger, M; Gassler, T; Sauer, M; Gasser, B; Mattanovich, D
10th Carbon Dioxide Utilisation Summit
(2018) Switching the metabolism of Pichia pastoris to efficiently assimilate CO2
Autoren: Gaßler, T; Gasser, B; Sauer, M; Steiger, M; Mattanovich, D;
10th ÖGMBT Annual Meeting & Biophysics Austria Annual Meeting 2018
(2018) Impact of puromycin on different Pichia pastoris strains
Autoren: Staudacher, J: Gasser, B;
10th ÖGMBT Annual Meeting & Biophysics Austria Annual Meeting 2018
(2018) Elucidation of the regulatory network of Trichoderma reesei operating under cellulose-degrading conditions
Autoren: Radebner, T; Wanka, F; Gasser, B; Seiboth, B;
14th European Conference on Fungal Genetics ECFG14 2018
(2018) Design and development of a comprehensive online resources for the biotechnological yeast Komagataellaphaffii
Autoren: Tatto, N; Valli, M; Gasser, B; Graf, A; Mattanovich, D
German Conference on Bioinformatics 2018
(2018) Design of novel Pichia pastoris promoters with high performance in methanol-free fed batch
Autoren: Gasser, B
5th BioProScale Symposium 2018
(2018) A synthetic yeast for efficient assimilation of carbon dioxide
Autoren: Gassler T; Gasser B; Sauer M; Steiger MG; Mattanovich D
Apllied Synthetic Biology in Europe 2018
(2018) A synthetic yeast for efficient assimilation of carbon dioxid
Autoren: Gaßler, T; Gasser, B; Sauer, M; Steiger MG; Mattanovich, D
4th Applied Synthetic Biology in Europe 2018
(2018) Characterization of O-glycans in recombinant proteins produces in Pichia pastoris,
Autoren: Radoman, B; Grünwald-Gruber, C; Schmelzer, B; Gasser, B; Mattanovich, D; Altmann, F
EMBO Practical Course - Characterization of post translational modifications in cellular signaling
(2018) Characterization of O-glycosylation in recombinant Pichia pastoris
Autoren: Radoman, B; Grünwald-Gruber, C; Rebnegger, C; Schmelzer, B; Altmann, F; Mattanovich, D; Gasser, B
EMBO Workshop - Enzymes, biocatalysis ans chemical biology: The new frontiers
(2018) The Cat8 transcription factors regulate carbon source utilization in Pichia pastoris
Autoren: Barbay, D; Mattanovich, D; Gasser, B
10th ÖGMBT Annual Meeting & Biophysics Austria Annual Meeting 2018
(2017) Enlarging the synthetic biology toolbox for Pichia pastoris: Golden Gate cloning and CRISPR/Cas9
Autoren: Gaßler, T; Prielhofer, R ; Heistinger, L; Zahrl, R; Zehetbauer, F; Steiger, M; Sauer, M; Gasser, B; Mattanovich, D;
Synthetic Biology Engineering Evolution Design SEED 2017
(2017) Role of epigenetic regulation in flocculation and pseido-hyphal growth of the protein production host Pichia pastoris
Autoren: De, S; Rebnegger, C; Mattanovich, D; Gasser, B;
European Summit of Industrial Biotechnology ESIB 2017
(2017) Promoter and process engineering for recombinant protein production in Pichia pastoris towards simple, fast and methanol-free cultivation regimes and high product titers
Autoren: Prielhofer, R; Reichinger, M; Wagner, N; Claes, K; Kiziak, C; Gasser, B; Mattanovich, D;
9th International Conference on Recombinant Protein Production RPP9 2017
(2017) Shedding light on the regulatory network of the fungus Trichoderma reesei operating under cellulose-degrading conditions
Autoren: Radebner, T; Wanka, F; Gasser, B; Seiboth, B;
2nd Symposium on Plant Biomass Conversion by Fungi
(2017) Identification of intracellular interaction partners of recombinant proteins
Autoren: Schmelzer, B; Grünwald-Gruber, C; Altmann, F; Gasser, B; Mattanovich, D;
9th International Conference on Recombinant Protein Production RPP9 2017
(2017) Promoter and process engineering for recombinant protein production in Pichia pastoris towards simple, fast and methanol-free cultivation regimes and high product titers
Autoren: Prielhofer, R; Reichinger, M; Wagner, N; Claes, K; Kiziak, Ch; Gasser, B; Mattanovich, D;
European Summit of Industrial Biotechnology ESIB 2017
(2017) Characterizing Vacuolar Protein Sorting Pathways in the Yeast Pichia Pastoris
Autoren: Marsalek, L; Grünwald-Gruber, C; Altmann, F; Mattanovich, D; Puxbaum, V; Gasser, B;
European Summit of Industrial Biotechnology ESIB 2017
(2017) Characterizing vacuolar protein sorting pathways in the yeast Pichia pastoris
Autoren: Gasser, B; Marsalek, L; Gruber, C; Altmann, F; Mattanovich, D; Puxbaum, V;
28th International Conference on Yeast Genetics and Molecular Biology ICYGMB 2017
(2017) Characterization of transcriptional regulatory proteins in Pichia pastoris
Autoren: Barbay, D; Mattanovich, D; Gasser, B;
28th International Conference on Yeast Genetics and Molecular Biology ICYGMB 2017
(2017) Omics-data integration into the genome-scale metabolic model of Pichia pastoris enables estimation of protein production in capabilities
Autoren: Pena-Navarro, D; Haltrich, D; Mattanovich, D; Gasser, B; Zanghellini, J;
9th International Conference on Recombinant Protein Production RPP9 2017
(2017) Identification of intracellular interaction partners of recombinant proteins
Autoren: Schmelzer, B; Grünwald-Gruber, C; Altmann, F; Gasser, B; Mattanovich, D;
European Summit of Industrial Biotechnology ESIB 2017
(2017) Synthetic biology toolbox and application for recombinant protein production in Pichia pastoris: Golden Gate cloning and CRISPR/Cas9.
Autoren: Prielhofer, R; Barrero, J; Steuer, S; Zahrl, R; Baumann, K; Heistinger, L; Jarych, D; Mattanovich, D; Gasser, B;
9th International Conference on Recombinant Protein Production RPP9 2017
(2017) An alternative approach to methanol driven protein production with Pichia pastoris
Autoren: Zavec, D; Gasser, B; Mattanovich, D;
European Summit of Industrial Biotechnology ESIB 2017
(2017) Shedding light on the regulatory network of the fungus Trichoderma reesei operating under cellulose-degrading conditions
Autoren: Radebner, T; Wanka, F; Gasser, B; Seiboth, B;
12th conference of the VAAM special group Molecular Biology by Fungi
(2017) Characterization of O-glycans in recombinant proteins produced in Pichia pastoris
Autoren: Radoman, B; Grünwald-Gruber, C; Schmelzer, B; Gasser, B; Altmann, F; Mattanovich, D;
European Summit of Industrial Biotechnology ESIB 2017
(2017) Shedding light on the regulatory network of the fungus Trichoderma reesei operating under cellulose-degrading conditions.
Autoren: Radebner, T; Wanka, F; Gasser, B; Seiboth, B;
2nd Symposium on Plant Biomass Conversion by Fungi
(2017) The regulatory network of Trichoderma reesei present under cellulase expressing conditions
Autoren: Radebner, T; Wanka, F; Gasser, B; Seiboth, B;
European Summit of Industrial Biotechnology ESIB 2017
(2017) Engineering protein quality control mechanisms and vesicular sorting pathways for efficient secretion of recombinant proteins
Autoren: Gasser, B;
Protein Engineering 2017
(2017) A binuclear mutant of Pichia pastoris was selected as an efficient recombinant protein producer
Autoren: Buchetics, M; Baumann, K; Valli, M; Grillitsch, K; Daum, G; Zellnig, G; Mattanovich, D; Gasser, B;
9th International Conference on Recombinant Protein Production RPP9 2017
(2017) Shedding light on the regulatory network of the fungus Trichoderma reesei operating under cellulose-degrading conditions.
Autoren: Radebner, T; Wanka, F; Gasser, B; Seiboth, B;
12th conference of the VAAM special group Molecular Biology by Fungi
(2017) RNA-Seq analysis protocol development for Komagataella phaffii
Autoren: Tatto, N; Moser, J; Gasser, B; Mattanovich, D; Graf, A;
ISMB/ECCB 2017
(2017) Role of epigenetic regulation in flocculation and pseudo-hyphal growth of the protein production host Pichia pastoris
Autoren: De, S; Rebnegger, C; Mattanovich, D; Gasser, B;
9th International Conference on Recombinant Protein Production RPP9 2017
(2017) Characterization of O-glycans in recombinant proteins produced in Pichia pastoris
Autoren: Radoman, B; Grünwald-Gruber, C; Schmelzer, B; Gasser, B; Altmann, F; Mattanovich, D;
9th International Conference on Recombinant Protein Production RPP9 2017
(2017) Omics-data integration into the genome-scale metabolic model of Pichia pastoris enables estimation of protein production capabilities
Autoren: Pena-Navarro, DA; Haltrich, D; Mattanovich, D; Gasser, B; Zanghellini, J;
European Summit of Industrial Biotechnology ESIB 2017
(2017) Characterization of transcriptional regulatory proteins in Pichia pastoris
Autoren: Barbay, D; Mattanovich, D; Gasser, B;
European Summit of Industrial Biotechnology ESIB 2017
(2017) Enlarging the Synthetic Biology Toolbox for Pichia Pastoris: Golden Gate Cloning and CRISPR/Cas9
Autoren: Gaßler, T; Prielhofer, R; Heistinger, L; Zahrl, R; Zehetbauer, F; Steiger, M; Sauer, M; Gasser, B; Mattanovich, D;
Synthetic Biology Engineering Evolution Design SEED 2017
(2017) Creation of Pichia pastoris strains with stable mating-types for the production of multimeric proteins
Autoren: Heistinger, L; Gasser, B; Mattanovich, D;
9th International Conference on Recombinant Protein Production RPP9 2017
(2017) Methanol utilization negative strains of Pichia pastroris for recombinant protein production
Autoren: Zavec, Domen; Puxbaum, V; Gasser, B; Mattanovich, D;
9th International Conference on Recombinant Protein Production RPP9 2017
(2017) RNASeq protocol development for K. phaffii
Autoren: Tatto, N; Moser, J; Gasser, B; Mattanovich, D; Graf, A;
European Summit of Industrial Biotechnology ESIB 2017
(2017) The regulatory network of Trichoderma reesei under cellulase expressing conditions
Autoren: Radebner, T; Wanka, F; Gasser, B; Seiboth, B;
European Summit of Industrial Biotechnology ESIB 2017
(2016) Curation of the Pichia pastoris (Komagatella phaffi) genome annotation by integration of RNA-Seq and proteomic data
Autoren: Valli, M; Tatto, N; Peymann, A; Gruber, C; Landes, N; Ekker, H; Thallinger, G; Mattanovich, D; Gasser, B; Graf, A
ESIB 2016
(2016) Methanol metabolism revisited: The xylulose-monophosphate cycle of methanol assimilation utilizes a duplicated methanol inducible enzyme set and is entirely localized to peroxisomes
Autoren: Rußmayer, H; Buchetics, M; Gruber, C; Valli, M; Grillitsch, K; Modarres, G; Drexler, H; Steiger, M; Daum, G; Graf, A; Altmann, F; Hann, S; Sauer, M; Mattanovich, D; Gasser, B;
Pichia 2016
(2016) On the relation of growth and protein secretion in budding yeasts
Autoren: Rebnegger, C; Puxbaum, V; Buchetics, M; Gasser, B; Mattanovich, D;
14th International Congress on Yeasts - ICY 2016
(2016) On the coupling of growth and protein secretion in budding yeasts
Autoren: Rebnegger C; Puxbaum V; Buchetics M; Gasser B; Mattanovich D
14th International Congress on Yeasts 2016
(2016) Matching the demand of protein production by metabolic engineering of the central metabolism: lessons learned from cofactor and amino acid metabolism in yeasts
Autoren: Mattanovich, D; Russmayer, H; Nocon, J.; Hohlweg, J; Steiger, M; Sauer, M; Gasser, B;
11th Metabolic Engineering 2016
(2016) Matching the demand of protein production by metabolic engineering of the central metabolism: lessons learned from cofactor and amino acid metabolism in yeasts
Autoren: Russmayer H; Nocon J; Hohlweg J; Steiger MG; Sauer M; Gasser B; Mattanovich D
11th Metabolic Engineering 2016
(2016) A winding road to the bud tip - exploring the secretion route of recombinant proteins in Pichia pastoris via live cell microscopy,
Autoren: Puxbaum, V; Landes, N; Gasser, B; Mattanovich, D;
14th International Congress on Yeasts - ICY 2016
(2016) Studying epigenetic regulation in fast and slow growing Pichia pastoris
Autoren: De, S; Rebnegger, C; Mattanovich, D; Gasser, B
PYFF6 - 6th Conference on Physiology of Yeasts and Filamentous Fungi
(2016) Cellular mechanisms of regulation during enzyme production in Trichoderma reesei.
Autoren: Radebner, T; Bischof, R; Gasser, B; Seiboth, B;
ESIB – European Summit of Industrial Biotechnology
(2016) Engineering protein quality control mechanisms and vesicular sorting pathways for efficient secretion of recombinant proteins
Autoren: Gasser, B;
14th International Congress on Yeasts - ICY 2016
(2016) The impact of ERAD on recombinant protein secretion in yeast
Autoren: Zahrl, R; Pfeffer, M; Mattanovich, D; Gasser, B
14th International Congress on Yeasts - ICY 2016
(2016) On the coupling of growth and protein secretion in budding yeasts
Autoren: Rebnegger, C; Puxbaum, V; Buchetics, M; Gasser, B; Mattanovich, D;
Power of Microbes in Industry and Environment
(2016) Identification of intracellular interaction partners of recombinant proteins
Autoren: Schmelzer, B; Grünwald-Gruber, C; Altmann, F; Gasser, B; Mattanovich, D;
ESIB – European Summit of Industrial Biotechnology
(2016) The impact of ERAD on recombinant protein secretion in yeast
Autoren: Zahrl, R; Pfeffer, M; Mattanovich, D; Gasser, B;
ESIB 2016
(2016) Studying epigenetic regulation in fast and slow growing Pichia pastoris
Autoren: De, S; Rebnegger, C; Mattanovich, D; Gasser, B;
ESIB 2016
(2016) pichiagenome.org - Database & Genome Browser
Autoren: Tatto, N; Valli, M; Mattanovich, D; Gasser, B; Graf, A;
ESIB 2016
(2016) Synthetic biology toolbox and application for recombinant protein production in Pichia pastoris; Golden Gate Cloning and CRISPR/Cas9
Autoren: Prielhofer, R; Barrero, J; Steuer, S; Zahrl, R; Baumann, K; Heistinger, L; Jarych, D; Zehetbauer, F; Mattanovich, M; Steiger, M; Marx, H; Sauer, M; Mattanovich, D; Gasser, B;
ESIB 2016
(2016) Secretome diversity of Pichia pastoris in the presence of different carbon sources
Autoren: Hohlweg, J; Gruber, C; Altmann, F; Valli, M; Mattanovich, D; Gasser, B;
ESIB 2016
(2016) Studying epigenetic regulation in fast and slow growing Pichia pastoris
Autoren: De, S; Rebnegger, C; Mattanovich, D; Gasser, B;
ECB17 - 17th European Biotechnology Congress
(2016) Engineering Pichia pastoris towards alternative carbon sources
Autoren: Gaßler, T; Steiger, M; Gasser, B; Sauer, M; Mattanovich, D
ESIB 2016
(2016) The impact of intracellular degradation on recombinant protein secretion in yeast
Autoren: Zahrl, R; Marsalek, L; Pfeffer, M; Mattanovich, D; Gasser, B;
Pichia 2016
(2016) A winding road to the bud tip - exploring the secretion route of recombinant proteins in Pichia pastoris via live cell microscopy
Autoren: Puxbaum V., Landes N., Gasser B., Mattanovich D.
14th International Congress on Yeasts 2016
(2016) Synthetic biology toolbox and application for recombinant protein production in Pichia pastoris: Golden Gate cloning and CRISPR/Cas9
Autoren: Prielhofer, R; Barrero, J; Steuer, S; Zahrl, R; Baumann, K; Heistinger, L; Jarych, D; Zehetbauer, F; Mattanovich, M; Steiger, M; Marx, H; Sauer, M; Mattanovich, D; Gasser, B;
Pichia 2016
(2016) Customizing the amino acid metabolism of Pichia pastoris for recombinant protein production
Autoren: Rußmayer, H; Buchetics, M; Hohlweg, J; Neubauer, S; Klavins, K; Steiger, M; Graf, A; Köllensperger, G; Hann, S; Sauer, M; Gasser, B; Mattanovich, D;
1st ACIB Workshop on Analytical Chemistry 2016
(2016) Curation of the Pichia pastoris genome annotation by integration of RNA-Seq and proteomic data
Autoren: Valli, M; Peymann, A; Gruber, C; Tatto, N; Mattanovich, D; Gasser, B; Graf, A;
Pichia 2016
(2016) Synthetic biology toolbox and application for recombinant protein production in Pichia pastoris
Autoren: Prielhofer, R; Barrero, J; Steuer, S; Zahrl, R; Baumann, K; Heistinger, L; Jarych, D; Mattanovich, D; Gasser, B;
Third meeting on Applied Synthetic Biology in Europe
(2016) Matching the demand of protein production by metabolic engineering of the central metabolism: lessons learned from cofactor and amino acid metabolism in yeasts
Autoren: Russmayer, H; Nocon, J.; Hohlweg, J; Steiger, M; Sauer, M; Gasser, B; Mattanovich, D;
11th Metabolic Engineering 2016
(2016) Systems-level organization of yeast methylotrophic lifestyle: The xylulose-monophosphate cycle of methanol assimilation utilizes a duplicated methanol inducible enzyme set and is entirely localized to peroxisomes
Autoren: Rußmayer, H; Buchetics, M; Gruber, C; Valli, M; Grillitsch, K; Modarres, G; Drexler, H; Steiger, M; Daum, G; Graf, A; Altmann, F; Hann, S; Sauer, M; Mattanovich, D; Gasser, B;
PYFF6 - 6th Conference on Physiology of Yeasts and Filamentous Fungi
(2015) Pichia pastoris regulates its gene-specific response to differtent carbon sources at the transcriptional, rather than the translational, level
Autoren: Prielhofer, Roland, Cartwright, Stephanie, Graf, Alexandra, Valli, Minoska, Mattanovich, Diethard, Gasser, Brigitte
ACIB Science Days 2015
(2015) The Pichia pastoris secretome in fed-batch cultivations is carbon source independent
Autoren: Hohlweg, Jonas, Gruber, Clemens, Altmann, Friedrich, Valli, Minoska, Mattanovich, Diethard, Gasser, Brigitte
ACIB Science Days 2015
(2015) The impact of degradative pathways on recombinant protein secretion in Pichia pastoris
Autoren: Zahrl, Richard; Pfeffer, Martin; Mattanovich, Diethard; Gasser, Brigitte
ISSY32 - 32nd International Specialized Symposium on Yeasts
(2015) The impact of degradative pathways on recombinant protein secretion in Pichia pastoris
Autoren: Zahrl, Richard, Peffer, Martin, Mattanovich, Dietahard, Gasser, Brigitte
International Specialized Symposium on Yeast 2015
(2015) Expression of C-terminal Fab fragment variants: the host determines the best variant
Autoren: Goengrich, Rebecca, Kiziak, Christoph, Mattanovich, Diethard, Gasser, Brigitte
8th Conference on Recombinant Protein Production RPP8 2015
(2015) The impact of ERAD on recombinant protein secretion in yeast
Autoren: Zahrl, Richard, Pfeffer, Martin, Mattanovich, Diethard, Gasser, Brigitte
Pichia postoris Aft1 - a novel transcription factor, enhancing recombinant protein secretion
(2015) Tools for gene expression in Pichia pastoris
Autoren: Heistinger, Lina, Gasser, Brigitte, Mattanovich, Diethard
8th Conference on Recombinant Protein Production RPP8 2015
(2015) Regulation of mating in the methylotophic yeast Pichia pastoris
Autoren: Heistinger, Lina, Gasser, Brigitte, Mattanovich, Diethard
27th International Conference on Yeast Genetics and Molecular Biology ICYGMB 2015
(2015) Regulation of mating in the methylotrophic yeast Pichia pastoris
Autoren: Heistinger, L; Gasser, B; Mattanovich, D
27th International Conference on Yeast Genetics and Molecular Biology ICYGMB 2015
(2015) The xyluloaw-monophoaphate cyl of methanol assimilation utilizes of duplicate mehtanol inducible enzyme set and is entireley localized to peroxicomes
Autoren: Gasser, Brigitte
27th International conference on yeast genetics and molecular biology 2015
(2015) Secretome diversity of Pichia Pastoris in the presence of different carbon sources
Autoren: Hohlweg, J; Gruber, C; Altmann, F; Valli, M; Mattanovich, D; Gasser, B
27th International Conference on Yeast Genetics and Molecular Biology ICYGMB 2015
(2015) Follow the protein: the secretory pathway of recombinant proteins in Pichia pastoris tracked via live cell microscopy
Autoren: Puxbaum V., Landes N., Maccani A., Kunert R., Gasser B., Mattanovich D.
6th International Conference on Analysis of Microbial Cells at the Single Cell Level 2015
(2015) Pichia pastoris regulates its gene-specific response to different carbon sources at the transcriptional, rather than the translational, level
Autoren: Prielhofer, Roland, Cartwright, Stephanie, Graf, Alexandra, Valli, Minoska, Bill, Roslyn, Mattanovich, Diethard, Gasser, Brigitte
8th Conference on Recombinant Protein Production RPP8 2015
(2015) Mehtanol induced changes on the transciptome, proteome, metabolome and fluxome of Pichia pastoris
Autoren: Russmayer, Hannes, Buchetics, Markus, Graf, Alexandra, Valli, Minoska, Gruber, Clemens, Modarres, Gerda, Altmann, Friedrich, Guerrasio, Raffaelle, Klavins, Kristaps, Neubauer, Stefan, Stiefer, Matthias, Chalabi Ali Al, Krebiehl, Guido, Sonntag, Denise, Haberhauer-Troyer, Christina, Köllensperger, Gunda, Hann Stephan, Sauer, Michael, Gasser, Brigitte, Mattanovich, Diethard
8th Conference on Recombinant Protein Production RPP8 2015
(2015) The xylulose-monophosphate cycle of methanol assimilation utilizes a duplicated methanol inducible enzyme set and is entirely localized to peroxisomes
Autoren: Gasser, B; Russmayer, H; Buchetics, M; Gruber, C; Valli, M; Grillitsch, K; Modarres, G; Drexler, H; Steiger, M; Daum, G; Graf, AB; Altmann, F; Hann, S; Sauer, M; Mattanovich, D
27th International Conference on Yeast Genetics and Molecular Biology ICYGMB 2015
(2015) Tracking secretion of recombinant proteins in Pichia pastoris using live cell microscopy
Autoren: Puxbaum V., Landes N., Maccani A., Kunert R., Gasser B., Mattanovich D.
EMBO/EMBL Symposium Seeing is Believing - Imaging the Processes of Life
(2015) Follow the protein: the secretory pathway of recombinant proteins in Pichia pastoris tracked via live cell microscopy
Autoren: Puxbaum V., Landes N., Maccani A., Kunert R., Gasser B., Mattanovich D.
6th International Conference on Analysis of Microbial Cells at the Single Cell Level 2015
(2015) The Pichia pastoris secretome in fed-batch cultivations is carbon source independent
Autoren: Hohlweg, Jonas, Gruber, Clemens, Altmann, Friedrich, Valli, Minoska, Mattanovich, Diethard, Gasser, Brigitte
8th Conference on Recombinant Protein Production RPP8 2015
(2015) Dissection of growth rate and cell cycle dependent gene regulation in Pichia pastoris
Autoren: Rebnegger, Corinna, Hohlweg, Jonas, Graf Alexandra, Valli, Minoska, Gasser, Brigitte and Mattanovich, Diethard
8th Conference on Recombinant Protein Production RPP8 2015
(2015) Secretome diversity of Pichia pastoris in the presence of different carbon sources
Autoren: Hohlweg, Jonas, Gruber, clemens, Altmann, Friedrich, Valli, Minoska, Mattanovich, Diethard, Gasser, Brigitte
27th International Conference on Yeast Genetics and Molecular Biology ICYGMB 2015
(2014) Model based engineering of Pichia pastoris central metabolism enhances recombinant protein production
Autoren: Nocon, Justyna; Steiger, Matthias; Pfeffer, Martin; Sohn, Seung Bum; Kim, Tae Yong; Maurer, Michael; Russmayer, Hannes; Pflügl, Stefan; Ask, Magnus; Haberhauer-Troyer, Christina; Ortmayr, Karin; Hann, Stephan; Köllensperger, Gunda; Gasser, Brigitte; Lee, Sang Yup; Mattanovich, Diethard
ECB16 2014
(2014) "Model based engineering of Pichia pastoris central metabolism enhances recombinant protein production"
Autoren: Hoppe, Frederik; Schillinger, Harald; Schrafvogl, Rudolf; Hutter, Melanie; Kunert, Renate; Eyer, Kurt; Maurer, Michael
5th International Conference on Biomolecular Engineering (ICBE)
(2014) Redox regulation in ER and cytosol in response to increased oxidative protein folding and ER stress
Autoren: Delic, Maricela; Puxbaum, Verena; Mattanovich, Diethard; Gasser, Brigitte
EMBO Workshop Protein and lipid function in secretion and endocytosis
(2014) Redox regulation in ER and cytosol in response to increased oxidative protein folding and ER stress
Autoren: Delic, M; Borth, N; Landes, N; Maccani, A; Ernst, W; Puxbaum, V; Mattanovich, D; Gasser, B
CHOgenome Workshop 2014
(2014) Multistep processing of the secretion leader of the CRISP family member Epx1 in Pichia pastoris and implications on protein localization
Autoren: Heiss, Silvia; Puxbaum, Verena; Gruber, Clemens; Altmann, Friedrich; Mattanovich, Diethard and Gasser, Brigitte
EMBO Workshop Protein and lipid function in secretion and endocytosis
(2014) Systems biology & Systems biotechnology of Pichia pastoris
Autoren: Gasser, Brigitte
ECB16 2014
(2014) Cross-species comparison of recombinant protein secretion in CHO cells and Pichia pastoris
Autoren: Landes, Nils; Maccani, Andreas; Leitner, Christian; Maurer, Michael; Gasser, Brigitte; Ernst, Wolfgang; Kunert, Renate; Mattanovich, Diethard
CHOgenome Workshop 2014
(2014) Cross-species comparison of recombinant protein secretion in CHO cells and Pichia pastoris
Autoren: Landes, Nils; Maccani, Andreas; Leitner, Christian; Maurer, Michael; Graf, Alexandra; Valli, Minoska; Gruber, Clemens; Modarres, Gerda; Altmann, Friedrich; Gasser, Brigitte; Ernst, Wolfgang; Kunert, Renate; Mattanovich, Diethard
ECB16 2014
(2014) Influence of recombinant protein expression on the proteome of Pichia pastoris
Autoren: Gruber, Clemens; Landes, Nils; Valli, Minoska; Modarres, Gerda; Gasser, Brigitte; Graf, Alexandra; Altmann, Friedrich; Mattanovich, Diethard
6th ÖGMBT Annual Meeting 2014 - Life Sciences meet Entrepreneurship
(2014) Control of redox conditions in the endoplasmic reticulum by redox-active proteins and transporters
Autoren: Delic, Maricela; Puxbaum, Verena; Gasser, Brigitte; Mattanovich, Diethard
EMBO Conference 2014 - The Endoplasmic Reticulum (ER) as a hub for organelle communication
(2014) The impact of ERAD on recombinant protein secretion in yeast
Autoren: Zahrl, Richard; Pfeffer, Martin; Mattanovich, Diethard; Gasser, Brigitte
EMBO Conference 2014 - The Endoplasmic Reticulum (ER) as a hub for organelle communication
(2014) Methanol induced changes on the transcriptome, proteome, metabolome and fluxome of Pichia pastoris
Autoren: Rußmayer, Hannes; Buchetics, Markus; Graf, Alexandra; Valli, Minoska; Gruber, Clemens; Modarres, Gerda; Altmann, Friedrich; Guerrasio, Raffaelle; Klavins, Kristaps; Neubauer, Stefan; Steiger, Matthias; Chalabi, Ali Al; Krebiehl, Guido; Sonntag, Denise; Haberhauer-Troyer, Christina; Köllensperger, Gunda; Hann, Stephan; Sauer, Michael; Gasser, Brigitte; Mattanovich, Diethard
ACIB-UAB Workshop - Systems Biology for Metabolic Engineering
(2014) Combinatorial genetic engineering in Pichia pastoris GoldenGate vs. Cre/loxP-based cloning approaches
Autoren: Baumann, Kristin; Barrero Peña, Juanjo; Marx, Hans; Gasser, Brigitte and Mattanovich, Diethard
ACIB-UAB Workshop - Systems Biology for Metabolic Engineering
(2014) Proteomic study of Pichia pastoris cell compartments
Autoren: Gruber, C; Grillitsch, K-H; Klug, L; Valli, M; Gasser, B; Mattanovich, D; Daum, G; Altmann, F
APRS 2014
(2014) Multistep processing of the secretion leader of the CRISP family member Epx1 in Pichia pastoris and implications on protein localization
Autoren: Heiss, Silvia; Puxbaum, Verena; Gruber, Clemens; Altmann, Friedrich; Mattanovich, Diethard and Gasser, Brigitte
ACIB-UAB Workshop - Systems Biology for Metabolic Engineering
(2014) Methanol induced changes on the transcriptome, proteome, metabolome and fluxome of Pichia pastoris
Autoren: Rußmayer, Hannes; Buchetics, Markus; Graf, Alexandra; Valli, Minoska; Gruber, Clemens; Modarres, Gerda; Altmann, Friedrich; Guerrasio, Raffaelle; Klavins, Kristaps; Neubauer, Stefan; Steiger, Matthias; Chalabi, Ali Al; Krebiehl, Guido; Sonntag, Denise; Haberhauer-Troyer, Christina; Köllensperger, Gunda; Hann, Steph
ACIB-UAB Workshop - Systems Biology for Metabolic Engineering
(2014) Proteomic study of Pichia pastoris cell compartments
Autoren: Gruber, C; Landes, N; Valli, M; Modarres, G; Gasser, B; Graf, AB; Altmann, F; Mattanovich, D
6th ÖGMBT Annual Meeting 2014 - Life Sciences meet Entrepreneurship
(2013) Redox regulation in ER and cytosol differs during oxidative protein folding *** ER stress
Autoren: Delic, M; Mattanovich, D; Gasser, B
26th International Conference on Yeast Genetics and Molecular Biology 2013
(2013) Metabolic model-based prediction of engineering targets for increased production of heterologous proteins
Autoren: Nocon, J., Pfeffer, M., Sohn, S.B., Kim, T.Y., Maurer, M., Gasser, B., Lee, S.Y., Mattanovich, D.
7th Conference on Recombinant Protein Production RPP7 2013
(2013) Overexpression of the redox transcription factor Yap1 modifies intracellular redox conditions and enhances recombinant protein secretion
Autoren: Delic, M; Rebnegger, C; Graf, AB; Mattanovich, D; Gasser, B.
7th Conference on Recombinant Protein Production RPP7 2013
(2013) Regulation of recombinant protein secretion in relation to growth in Pichia pastoris
Autoren: Rebnegger, C; Valli, M; Graf, A; Gasser, B; Maurer, M; Mattanovich, D
26th International Conference on Yeast Genetics and Molecular Biology 2013
(2013) Folding and secretion of heterologous proteins in yeasts – A genome scale perspective
Autoren: Gasser, B.
5th Conference on Physiology of Yeast and Filamentous Fungi PYFF5 2013
(2013) Influence of carbon source on the Pichia pastoris proteome
Autoren: C. Gruber1)2), M. Buchetics1)3), G. Modarres1)3),B. Gasser1)3), A.B.Graf1)4), F. Altmann1)2)and D. Mattanovich1)3) Gruber, C; Buchetics, M; Modarres, G; Gasser, B; Graf, AB; Altmann, F; Mattanovich, M
11th Austrian Proteomic Research Symposium
(2013) Cross-species comparison of recombinant protein secretion in CHO cells and Pichia pastoris
Autoren: Landes, N; Maccani, A; Leitner, C; Maurer, M; Gasser, B; Ernst, W; Kunert, R; Mattanovich, D.
7th Conference on Recombinant Protein Production RPP7 2013
(2013) Induction without methanol: Novel regulated promoters enable high- level expression in Pichia pastoris
Autoren: Prielhofer, R; Maurer, M; Klein, J; Wenger, J; Kiziak, C; Gasser, B; Mattanovich, D.
7th Conference on Recombinant Protein Production RPP7 2013
(2013) Regulation of recombinant protein secretion in relation to cell growth in the methylotrophic yeast Pichia pastoris
Autoren: Rebnegger, C; Graf, AB; Valli, M; Buchetics, M; Gasser, B; Maurer, M; Mattanovich, D.
7th Conference on Recombinant Protein Production RPP7 2013
(2013) Multistep processing of the secretion leader of the CRISP family member Epx1 in Pichia pastoris and implications on protein localization
Autoren: Gasser, B; Heiss, S; Puxbaum, V; Gruber, C; Altmann, F; Mattanovich, D
26th International Conference on Yeast Genetics and Molecular Biology 2013
(2013) Metabolic model-based prediction of engineering targets for increased production of heterologous proteins
Autoren: Nocon, J; Pfeffer, M; Sohn, SB; Kim, TY;, Maurer, M; Rußmayer, H; Steiger, M; Haberhauer-Troyer, C; Hann, S; Köllensperger, G;, Gasser, B; Lee, SY; Mattanovich, D.
Quantitative Biology: Current concepts and tools for microbial strain and process development
(2012) Oxidative protein folding and unfolded protein response elicit differing redox regulation in endoplasmic reticulum and cytosol of yeast
Autoren: Delic, M; Rebnegger, C; Wanka, F; Puxbaum, V; Mattanovich, D; Gasser, B
Physiology of the ER
(2012) Overexpression of the redox transcription factor Yap1 modifies intracellular redox conditions and enhances recombinant protein secretion
Autoren: Delic, M; Rebnegger, C; Alexandra B. Graf, AB; Mattanovich, D; Gasser, B.
13th International Congress on Yeasts 2012
(2012) Reverse Engineering of Protein Secretion by Uncoupling of Cell Cycle Phases From Growth
Autoren: Buchetics, M., Dragosits, M., Maurer, M., Rebnegger, C., Porro, D., Sauer, M., Gasser, B., Mattanovich, D
Pichia 2012
(2012) Evaluation of recoveries of cell extraction and overall sample preparation using a U13C cell extract
Autoren: Neubauer, S., Klavins, K., Haberhauer-Troyer, C., Steiger, M.G., Gasser, B., Sauer, M., Mattanovich, D., Hann, S. and Köllensperger, G.
60th ASMS Conference on Mass Spectrometry and Allied Topics 2012
(2012) Development of synthetic protein production platforms based on systems biology
Autoren: Gasser, B., Mattanovich, D.
Applied Synthetic Biology in Europe 2012
(2011) Monitoring intracellular redox conditions in the endoplasmic reticulum of living yeasts
Autoren: Delic, M., Mattanovich, D., Gasser, B.
6th Conference on Recombinant Protein Production RPP6 2011
(2011) Characterizing secretion behaviour of recombinant proteins in Pichia pastoris
Autoren: Puxbaum, V., Ertl, S., Gasser, B., Mattanovich, D.
Non-Conventional Yeasts in the Postgenomic Era NCY 2011
(2011) Characterization of cell cycle mutants in Pichia pastoris
Autoren: Schneider, F., Buchetics, M., Maurer, M., Mattanovich, D., Gasser, B.
25th International Conference on Yeast Genetics and Molecular Biology 2011
(2011) The stressful life of Pichia pastoris producing recombinant protein
Autoren: Mattanovich, D., Gasser, B., Dragosits, M., Delic, M., Graf, A.B., Maurer, M., Sauer, M., Baumann, K., Ferrer, P.,
6th Conference on Recombinant Protein Production RPP6 2011
(2011) Environmental and intrinsic stress in Pichia pastoris producing recombinant protein
Autoren: Mattanovich, D., Gasser, B., Dragosits, M., Delic, M., Graf, A.B., Maurer, M., Sauer, M., Baumann, K., Ferrer, P.
FEMS 2011 - 4th Congress of European Microbiologists
(2011) Characterizing secretion behaviour of recombinant proteins in Pichia pastoris
Autoren: Puxbaum, V., Ertl, S., Gasser, B., Mattanovich, D.
Non-Conventional Yeasts in the Postgenomic Era NCY 2011
(2011) Identification and characterization of the secretory cysteine-rich protein family member Epx1 in Pichia pastoris
Autoren: Heiss, S., Dragosits, M., Marx, H., Maurer, M., Puxbaum, V., Mattanovich, D., Gasser, B.
25th International Conference on Yeast Genetics and Molecular Biology 2011
(2011) Reverse Engineering of Protein Secretion by Uncoupling of Cell Cycle Phases From Growth
Autoren: Buchetics M., Dragosits M., Maurer M., Rebnegger C., Porro D., Sauer M., Gasser B., Mattanovich D.
6th Conference on Recombinant Protein Production RPP6 2011
(2011) Oxidative protein folding and unfolded protein response elicit different redox regulation in ER and cytosol of the yeast Pichia pastoris
Autoren: Delic, M., Rebnegger, C., Wanka, F., Haberhauer-Troyer, C., Köllensperger, G., Hann, S., Mattanovich, D., Gasser, B.
Non-Conventional Yeasts in the Postgenomic Era NCY 2011
(2011) Metabolite analyses in the protein production host Pichia pastoris
Autoren: Rußmayer, H., Guerrasio, R., Klavins, K., Neubauer, S., Steiger, M., Haberhauer-Troyer C., Koellensperger, G., Hann, S., Sauer, M., Gasser, B., Mattanovich, D.
3rd ÖGMBT Annual Meeting 2011
(2011) Oxidative protein folding and unfolded protein response elicit different redox regulation in ER and cytosol of yeast
Autoren: Delic, M., Rebnegger, C., Wanka, F., Haberhauer-Troyer, C., Köllensperger, G., Hann, S., Mattanovich, D., Gasser, B.
ESF-EMBO Conference on Glutathione and Related Thiols in Living Cells 2011
(2011) Novel promoters for protein production in Pichia pastoris
Autoren: Stadlmayr*, G., Mecklenbräuker*, A., Rothmüller, M., Maurer, M., Sauer, M., Mattanovich, D., Gasser, B.
6th Conference on Recombinant Protein Production RPP6 2011
(2011) Engineering of biotin prototrophy in Pichia pastoris for robust protein production processes
Autoren: Gasser, B., Dragosits, M., Mattanovich D.
6th Conference on Recombinant Protein Production RPP6 2011
(2011) Genome-scale modeling of the methylotrophic yeast Pichia pastoris for heterologous protein production
Autoren: Sohn*, S.B., Graf*, A. B., Kim, T. Y., Gasser, B., Maurer, M., Ferrer, P., Mattanovich, D., Lee, S. Y.
6th Conference on Recombinant Protein Production RPP6 2011
(2011) Identification and characterization of the secretory cysteine-rich protein family member Epx1 in Pichia pastoris
Autoren: Heiss, S., Dragosits, M., Marx, H., Maurer, M., Puxbaum, V., Mattanovich, D., Gasser, B.
25th International Conference on Yeast Genetics and Molecular Biology 2011
(2010) Engineering of biotin prototrophy in Pichia pastoris for robust protein production processes
Autoren: Gasser, B., Dragosits, M., Mattanovich D..
4th Conference on Physiology of Yeast and Filamentous Fungi PYFF4 2010
(2010) Engineering of biotin prototrophy in Pichia pastoris for robust protein production processes
Autoren: Gasser, B., Dragosits, M., Mattanovich D.
13th Metabolic Engineering 2010
(2010) Genome, secretome and glucose transport highlight unique features of the protein production host Pichia pastoris
Autoren: Mattanovich, D., Graf, A.B., Stadlmann, J., Dragosits, M., Redl, A., Maurer, M., Sauer, M., Altmann, F., Gasser, B.
4th Conference on Physiology of Yeast and Filamentous Fungi PYFF4 2010
(2010) Systems Biotechnology for Protein Production in Pichia pastoris
Autoren: Mattanovich, D., Graf, A.B., Stadlmann, J., Dragosits, M., Redl, A., Maurer, M., Sauer, M., Altmann, F., Gasser, B..
Systems Biology of Microorganisms
(2010) Genome sequence, secretome and sugar transport of the protein production host Pichia pastoris
Autoren: Mattanovich, D., Graf, A.B., Stadlmann, J., Dragosits, M., Redl, A., Maurer, M., Sauer, M., Altmann, F., Gasser, B..
Systems Biology of Microorganisms
(2010) Monitoring intracellular redox conditions in the endoplasmic reticulum of living yeasts
Autoren: Delic, M., Mattanovich, D.,Gasser B.
4th Conference on Physiology of Yeast and Filamentous Fungi PYFF4 2010
(2009) Proteomic and Transcriptomic Analysis of the Adaption of Pichia pastoris Cells to Various Environmental Conditions
Autoren: Dragosits Martin, Johannes Stadlmann, Alexandra Graf, Joan Albiol, Kristin Baumann, Brigitte Gasser, Michael Sauer, Friedrich Altmann, Pau Ferrer, Diethard Mattanovich
MICROBIAL STRESS 2009
(2009) Engineering of biotin prototrophy in yeasts
Autoren: Gasser Brigitte, Mattanovich Diethard
25th International Conference on Yeast Genetics & Molecular Biology 2009
(2009) Stress in recombinant protein producing yeasts
Autoren: Brigitte Gasser, Martin Dragosits, Alexandra Graf, Michael Maurer, Hans Marx, Astrid Mecklenbräuker, Michael Sauer, Diethard Mattanovich
MICROBIAL STRESS 2009
(2009) Measuring intracellular redox conditions in recombinant protein producing Pichia pastoris strains
Autoren: Delic, M., Mattanovich, D., Gasser, B.
25th International Conference on Yeast Genetics & Molecular Biology 2009
(2009) Engineering Pichia pastoris in the genomics era
Autoren: Mattanovich Diethard, Gasser Brigitte, Graf Alexandra , Dragosits Martin, Sauer Michael , Maurer Michael,
25th International Conference on Yeast Genetics & Molecular Biology 2009
(2009) Genome sequence, secretome and sugar transport of the protein production host Pichia pastoris
Autoren: Mattanovich Diethard, Graf Alexandra, Stadlmann Johannes, Dragosits Martin, Redl Andreas, Maurer Michael, Sauer Michael, Altmann Friedrich, Gasser Brigitte
25th International Conference on Yeast Genetics & Molecular Biology 2009
(2009) Genome scale engineering of protein production in Pichia pastoris
Autoren: Mattanovich Diethard; Graf Alexandra; Dragosits Martin; Stadlmann Johannes; Redl Andreas; Sauer Michael; Maurer Michael; Altmann Friedrich; Gasser Brigitte
Autumn Meeting of the Society for General Microbiology 2009
(2009) Genome sequence, secretome and sugar transport of the protein production host Pichia pastoris
Autoren: Mattanovich, D; Graf, A; Stadlmann, J; Dragosits, M; Redl, A; Maurer, M; Sauer, M; Altmann, F; Gasser, B.
14th European Congress on Biotechnology 2009
(2009) Yeast Systems Biotechnology for the Production of Heterologous Proteins
Autoren: Diethard Mattanovich, Martin Dragosits, Alexandra Graf, Andreas Redl, Johannes Stadlmann, Michael Maurer, Kristin Baumann, Joan Sola, Pau Ferrer, Friedrich Altmann, Michael Sauer, Brigitte Gasser
16th Biochemical Engineering 2009 - Past, Present, and Future of Biochemical Engineering
(2008) Monitoring proteome and transcriptome of recombinant Pichia pastoris at different cultivation temperatures
Autoren: Martin Dragosits, Johannes Stadlmann, Michael Maurer, Kristin Baumann, Joan Albiol Sala, Alexandra Graf, Brigitte Gasser, Michael Sauer, Pau Ferrer, Friedrich Altmann, and Diethard Mattanovich
5th EFB Meeting on Recombinant Protein Production RPP 2008
(2008) Physiological characterization and strain engineering of Pichia pastoris by transcriptomics and proteomics
Autoren: Gasser Brigitte
4th Swiss-Czech Symposium BioTech 2008
(2008) Novel promoters for protein production in Pichia pastoris
Autoren: Gerhard Stadlmayr, Astrid Mecklenbräuker, Marion Rothmüller, Michael Sauer, Diethard Mattanovich, Brigitte Gasser
5th EFB Meeting on Recombinant Protein Production RPP 2008
(2008) A Chemostat based Study on the Influence of Temperature on the Physiology of Recombinant Pichia pastoris
Autoren: Martin Dragosits, Johannes Stadlmann, Michael Maurer, Brigitte Gasser, Michael Sauer and Diethard Mattanovich
Workshop Functional Genomics and Industrial Biocatalysis 2008
(2008) High throughput screening for factors enhancing protein secretion secretion in yeasts
Autoren: Brigitte Gasser*, Gerhard Stadlmayr*, Michael Sauer, Michael Maurer, Katrin Benakovitsch, Diethard Mattanovich
5th EFB Meeting on Recombinant Protein Production RPP 2008
(2008) High throughput screening for factors enhancing protein production and secretion with Pichia pastoris
Autoren: Gerhard Stadlmayr, Katrin Benakovitsch, Brigitte Gasser, Michael Sauer, Diethard Mattanovich
4th Swiss-Czech Symposium BioTech 2008
(2008) A proteomics and transcriptomics approach to the study of heterologous protein production in Pichia pastoris under different oxygen conditions
Autoren: Baumann K, Dragosits M, Stadlmann J, Graf A, Maurer M, Gasser B, Altmann F,Mattanovich D, Ferrer P
5th Conference on Recombinant Protein Production 2008
(2008) Monitoring proteome and transcriptome of recombinant Pichia pastoris at different cultivation temperatures
Autoren: Dragosits M, Stadlmann J, Maurer M, Baumann K, Albiol J, Graf A, Gasser B, Sauer M, Ferrer P, Altmann F, Mattanovich D
5th International Conference on Recombinant Protein Production
(2008) Physiological characterization and strain engineering of Pichia pastoris by transcriptomics and proteomics
Autoren: Gasser B, Dragosits M, Graf A, Sauer M, Maurer M, Stadlmayr G, Mattanovich D
Workshop Functional Genomics and Industrial Biocatalysis 2008
(2008) High throughput screening for factors enhancing protein production and secretion with Pichia pastoris
Autoren: Gerhard Stadlmayr, Katrin Benakovitsch, Brigitte Gasser, Michael Sauer, Diethard Mattanovich
4th International Conference on Analysis of Microbial Cells at the Single Cell Level 2008
(2008) Application of Pichia pastoris microarrays leads to novel insights into the Unfolded Protein Response
Autoren: Gasser B., Graf A., Dragosits M., Michael S., Leparc G., Kreil D. P., Mattanovich D
12th International Congress on Yeasts ICY 2008
(2008) Novel promoters for protein production in Pichia pastoris
Autoren: Gerhard Stadlmayr, Brigitte Gasser, Marion Rothmüller, Michael Sauer, Diethard Mattanovich
4th Swiss-Czech Symposium BioTech 2008
(2008) Novel insights into the unfolded protein response using Pichia pastoris specific DNA microarrays
Autoren: Brigitte Gasser*, Alexandra Graf*, Martin Dragosits, Michael Sauer, Germán G. Leparc, Thomas Tüchler, David P. Kreil, Diethard Mattanovich
5th EFB Meeting on Recombinant Protein Production RPP 2008
(2007) Molecular characterization and engineering of Pichia pastoris as a platform for antibody (fragment) production.
Autoren: Gasser B., Sauer M., Benakovitsch K., Maurer M., Stadlmayr G., Dragosits M., Mattanovich D.
15th Biochemical Engineering 2007
(2007) Novel helper factors for protein secretion in yeasts
Autoren: Gasser B., Sauer M., Maurer M., Benakovitsch K., Mattanovich D.
3rd EFB Conference on Physiology of Yeasts and Filamentous Fungi PYFF3 2007
(2007) Proteome regulation of Pichia pastoris expressing recombinant human antibody fragments
Autoren: Martin Dragosits, Johannes Stadlmann, Michael Maurer, Brigitte Gasser, Michael Sauer, Diethard Mattanovich
13th European Congress on Biotechnology 2007
(2006) Monitoring of transcript regulation and protein production related stress responses in Pichia pastoris secreting Fab antibody fragments
Autoren: Gasser B., Maurer M., Sauer M., Saloheimo M., Rautio J., Penttila M., Mattanovich D.
4th Recombinant Protein Production Meeting RPP EFB 2006 - A Comparative View on Host Physiology
(2006) High level expression of a humanised Ab2/3H6 Fab in Pichia pastoris.
Autoren: Gach, J.,Maurer, M., Quendler, H., Gasser, B., Löschel, M., Mattanovich, D., Katinger, H., Kunert, R.
Recombinant Antibodies
(2006) A rational approach to optimize feed profiles for the maximization of productivity of secreted proteins expressed in Pichia pastoris
Autoren: Michael Maurer, Brigitte Gasser, Manfred Kühleitner, Diethard Mattanovich
Bioengineering course
(2006) Identification of Physiological Bottlenecks hampering Heterologous Protein Expression in Pichia pastoris by Genomic and Proteomic Analysis
Autoren: Dragosits M, Gasser B, Maurer M, Kunert R and Mattanovich D
3rd Summer School in Proteomic Basics 2006 - Exploring the Diversity of Proteins
(2006) In vitro and in vivo characterization of an antiidiotypic antibody variants directed against the HIV-neutralizing mAb 2F5
Autoren: Kunert, R., Gach, J., Preis, S., Löschel M., Weik, R., Ferko, B., Stiegler, G., Gasser, B., Mattanivich, D., Katinger, H.
Human Antibodies and Hybridomas 2006
(2006) Monitoring of transcript regulation and protein production related stress responses in Pichia pastoris secreting Fab antibody fragments.
Autoren: Gasser, B., Maurer, M., Sauer, M., Saloheimo, M., Rautio, J., Penttila, M., Mattanovich, D.
Systems Biology of Yeasts – From Models to Applications
(2006) A rational approach to optimize feed profiles for the maximization of productivity of secreted proteins expressed in Pichia pastoris
Autoren: Maurer M., Gasser B., Kühleitner M., Mattanovich D.
4th Recombinant Protein Production Meeting RPP EFB 2006 - A Comparative View on Host Physiology
(2005) Impact of environmental and metabolic stresses on recombinant protein production in Pichia pastoris
Autoren: Gasser, B.
Friday Seminar Series - VTT Biotechnology
(2005) Multiple flow cytometry analysis as a tool for the study of microbial fermentations
Autoren: Maurer M., Gasser B., Benakovitsch K., Borth N. Mattanovich D.
3rd International EFB Conference 2005 - Analysis of Microbial Cells at the Single Cell Level
(2005) Anti-idiotypic antibodies, an alternatve strategy against HIV-1
Autoren: Johannes Gach, Boris Ferko, Brigitte Gasser, Diethardt Mattanovich, Hermann Katinger, Renate Kunert
60 Year Anniversary, Institute of Applied Microbiology IAM 2005
(2005) High throughput methods for strain improvement - Flow Cytometry & FACS
Autoren: Maurer M., Gasser B., Benakovitsch K., Valli M., Borth N., Mattanovich D.
60 Year Anniversary, Institute of Applied Microbiology IAM 2005
(2005) Anti-idiotypic antibodies an alternative strategy against HIV-1
Autoren: Gach, J., Ferko, B., Gasser, B., Mattanovich, D., Katinger, H., Kunert, R.
60 Year Anniversary, Institute of Applied Microbiology IAM 2005
(2005) Optimisation of protein secretion in antibody fragment expressing Pichia pastoris
Autoren: Gasser B., Maurer M., Kunert R., Mattanovich D.
60 Year Anniversary, Institute of Applied Microbiology IAM 2005
(2005) Flow cytometric analysis of antibody fragment secreting Pichia pastoris – Detection of folding stress by immunofluorescence
Autoren: Gasser B., Maurer M., Mattanovich D.
3rd International EFB Conference 2005 - Analysis of Microbial Cells at the Single Cell Level
(2005) High throughput methods for strain improvement - Microarrays
Autoren: Sauer M., Gasser B., Branduardi P., Maurer M., Wernitznig E., Porro D., Mattanovich D.
60 Year Anniversary, Institute of Applied Microbiology IAM 2005
(2004) Effects of gene dosage, promoters and substrates on unfolded protein stress of recombinant Pichia pastoris
Autoren: Gasser B., Hohenblum H., Maurer M., Borth N., Mattanovich D.
EFB Section Meeting “Physiology of Yeasts and Filamentous Fungi II”
(2004) Unfolded protein response in Pichia pastoris expressing the Rhizopus oryzae Lipase under the control of FLD1 promoter.
Autoren: Resina D., Gasser B., Maurer M., Valero F., Ferrer P., Mattanovich D.
EFB Section Meeting 2004 - Recombinant Protein Production with Prokaryotic and Eukaryotic Cells III
(2004) Differential gene expression in recombinant Pichia pastoris analysed by heterologous DNA microarray hybridisation
Autoren: Sauer M., Branduardi P., Gasser B., Valli M., Maurer M., Porro D., Mattanovich D.
EFB Section Meeting 2004 - Recombinant Protein Production with Prokaryotic and Eukaryotic Cells III
Enlarging the synthetic biology toolbox for Pichia pastoris: Golden Gate cloning and CRISPR/Cas9
Autoren: Gassler, T; Prielhofer, R; Heistinger, L; Zahrl, R; Zehetbauer, F; Steiger, MG; Sauer, M; Mattanovich, D; Gasser, B;
Multiple flow cytometry analysis as a tool for the study of microbial fermentations
Autoren: Maurer M., Gasser B., Benakovitsch K., Borth N., Mattanovich D.
Impact of environmental and metabolic stresses on recombinant protein production in Pichia pastoris.
Autoren: Gasser, B., Maurer, M., Hohenblum, H., Sauer, M., Valli, M., Branduardi, P., Porro, D., Mattanovich, D.
Versatile role of the FLO gene family and Implications for recombinant protein secretion, gene regulation and cell morphology.
Autoren: Gasser, B.
Systems bio(techno)logy approaches to protein production in Pichia pastoris
Autoren: Gasser, Brigitte
Engineering transcription regulation in Pichia pastoris.
Autoren: Flores Villegas, MC; Mattanovich, D; Gasser, B
Regulation of pseudohyphal growth and flocculation in Pichia pastoris
Autoren: De, S; Rebnegger, C; Moser, J; Tatto, N.E; Mattanovich, D; Gasser, B;
Making a strong promoter even stronger - Enhancing transcriptional activity of the glucose-regulated PG1 promoter by random mutagenesis and transcriptional engineering.
Autoren: Rebnegger, C; Flores- Villegas, M; Kowarz, V; Kiziak, Ch, Ongaro, A; Holm, H; Mattanovich, D; Gasser, B
Characterizing vacuolar protein sorting pathways for enhanced protein secretion in the yeast Pichia pastoris (Komagatella spp)
Autoren: Marsalek, L; Puxbaum, V; Gruber-Grünwald, C; Altmann, F; Mattanovich, D; Gasser, B
Regulation of mating in the methylotrophic yeast Komagatella phaffii
Autoren: Heistinger, L; Moser, J; Tatto, N.E; Valli, M; Gasser, B; Mattanovich, D
Preventing morphological cell heterogeneity in the yeast Pichia pastoris (syn Komagataella phaffii): involvement of the FLO gene family.
Autoren: De, S; Rebnegger, C; Buchetics, M; Moser, J; Tatto, N; Graf, AB; Mattanovich, D; Gasser, B.
Characterizing vacuolar protein sorting pathways in the yeast Pichia pastoris
Autoren: Marsalek, L; Gruber, C; Altmann, F; Mattanovich, D; Puxbaum, V; Gasser, B;
High Level Expression of a Humanised Ab2/3H6 Fab in Pichia Pastoris.
Autoren: Gach, J., Maurer, M., Quendler, H., Gasser, B., Löschel, M., Mattanovich, M., Katinger, H., Kunert, R.
Synthetic biology for efficient assimilation of carbon dioxide
Autoren: Gassler T; Gasser B; Sauer M; Steiger MG; Mattanovich D
The Cat8 transcription factors regulate carbon source utilization in Pichia pastoris
Autoren: Barbay, D; Mattanovich, D; Gasser, B
Engineering vacuolar sorting pathways for efficient secretion of recombinant proteins
Autoren: Marsalek, L; Gruber, C; Altmann, F; Mattanovich, D; Puxbaum, V; Gasser, B;
Enzyme promiscuity enables efficient recombinant protein production, on methanol, in an AOX deficient Pichia pastoris strain
Autoren: Coltman, B; Zavec, D; Mattanovich, D; Gasser, B; Zanghellini, J