Renate Kunert
Univ.Prof. Dipl.-Ing. Dr.nat.techn. Renate Kunert
Institut Institut für Tierische Zelltechnologie und Systembiologie
Standort Muthgasse 11, 1190 Wien
Email renate.kunert@boku.ac.at
Tel: +43 1 47654-79852
ORCID: 0000-0002-3397-3621
6603682350: AuthorId
B-9185-2018: ResearcherId
Forschungsschwerpunkt
medizinische Biotechnologie, Immunglobuline, Hormone, Oberflächenproteine, Komplementsystem, rekombinante Proteinexpression in tierischen Zellen, Bioprozesse, Proteinchemie
Laufbahn
- 2009 Professorin für tierische Zelltechnologie
- 2002 Habilitation zum Professor für biopharmazeutische Technologie
- 1994 Dissertation: Sequenzierung und systematische Charakterisierung von Genen humaner Antikörper gegen H
- 1989 Diplomarbeit: Sialo- und Asialoglykokonjugate als Immunogene: Herstellung, Charakterisierung und imm
Projekte
Es wurden 0 Projekte gefunden.
Publikationen
Wissentransfer in die Gesellschaft
Medienbeiträge
Vorträge
(2023) C1q-IgM interaction studies with recombinant globular C1q variants
Autoren: John, M.; Hunjadi, M.; Hawlin, V.; Kunert, R.
29th International Complement Workshop
(2023) Production of artificial globular C1q variants and performance of interaction studies with pentameric and hexameric IgM
Autoren: John, M.; Hunjadi, M.; Hawlin, V.; Kunert, R.
4th ESACT Frontiers Retreat
(2022) Functional Trimeric SARS-CoV-2 Envelope Protein Expressed in Stable CHO Cells
Autoren: Hunjadi, M; Mayrhofer, P; Abdur, R; Kunert, R
27th European Society for Animal Cell Technology ESACT Meeting 2022
(2022) Artificial C1q globular regions for C1q-IgM interaction studies
Autoren: John, M; Hunjadi, M; Billerhart, M; Sulaj, E; Hawlin, V; Kunert, R
27th European Society for Animal Cell Technology ESACT Meeting 2022
(2019) HIV-1 Envelope Glycoproteins as Immunogens - Expression and Manufacture
Autoren: Mundsperger, P; Kunert, R;
ESACT meeting
(2019) Evaluation of C1p binding and complement activation of new recombinant human IgMs as quality attributes.
Autoren: J.-B. Reiser, J. Hennicke, I. Bally, A. Chouquet, W.-L. Ling, F. Altmann, R. Kunrt, N. Thielens
17th European Meeting on Supercritical Fluids EMSF and 7th European Meeting on High Pressure Technology 2019
(2019) Gene expression changes in response to expressed mAb variant in CHO cells
Autoren: Schwaigerlehner, L; Akhtar, S; Scholey, R; Torres, M; Mayrhofer, P; Dickson, AJ; Kunert, R
14th Asian Congress on Biotechnology ACB 2019
(2019) DoE-supported media formulations in high density perfusion processes
Autoren: Kunert, R; Castan, A; Mayrhofer, P
2nd Global Bioprocessing, Bioanalytics & ATMP Manufacturing Congress
(2019) Influence of Somatic Mutations on mAb Expression and Thermal Stability Properties
Autoren: Kunert, R; Schwaigerlehner, L; Mayrhofer, P;
PEGS Europe 2019
(2019) DoE-supported perfusion medium development for maximum cell densities and optimized media consumption
Autoren: Mayrhofer, P; Damjanovic, L; Castan, A; Kunert, R
257th National Spring Meeting of the American Chemical Society ACS 2019
(2019) Process intensification through cell culture perfusion
Autoren: Patrick Mayrhofer, Renate Kunert
ESACT 2019
(2019) Does CHO gene expression change in response to expressed mAb variant?
Autoren: Schwaigerlehner, L; Kunert, R; Mayrhofer, P;
ESACT 2019
(2019) Pre-testing of media-composition for high density culture perfusion processes
Autoren: Kunert, Mayrhofer
2nd Global Bioprocessing, Bioanalytics & ATMP Manufacturing Congress
(2019) Historical background and story about first HIV mAs developed at Polymun/IAM
Autoren: Renate Kunert
Education and Training in EAVI - A European HIV vaccine Programme
(2018) Does the degree of antibody maturation influence expression rate and stability of mAbs?
Autoren: Kunert, R; Schwaigerlehner, L; Mayrhofer, P
HUMAN ANTIBODIES & HYBRIDOMAS 2018
(2018) Transcriptome analysis of a recombinant antibody-producing CHO cell line cultivated in feed-spiked medium
Autoren: Renate Kunert, David Reinhart, Lukas Damjanovic, Andreas Castan, Wolfgang Ernst
Bioprocessing Summit Europe 2018
(2018) Making the strange more familiar: Influence of germinality content on mAb expression potentials and thermal stability properties
Autoren: Schwaigerlehner, L; Mayrhofer, P; Kunert, R
18th European Congress On Biotechnology 2018
(2018) Does mAb germinality correlate with productivity and biophysical protein properties?
Autoren: Schwaigerlehner, L; Mayrhofer, P; Kunert, R
Antibody Engineering & Therapeutics 2018
(2018) Are somatic mutations of mAbs responsible for low expression and thermal stability?
Autoren: Schwaigerlehner, L; Mayrhofer, P; Kunert, R
10th ÖGMBT Annual Meeting & Biophysics Austria Annual Meeting 2018
(2018) CHO cell perfusion culture development beyond 200 × 10E6 cells/mL
Autoren: Mayrhofer, P; Wiederstein, F; Damjanovic, L; Castan, A; Kunert, R
BioProcess International European Summit 2018
(2018) Humanization of a mouse antibody and subsequent analysis of expected immunogenicity by molecular dynamics simulations and in-silico T-cell epitope predictions.
Autoren: Mayrhofer, P; Schwaigerlehner, L; Oostenbrink, C; Kunert, R
Antibody Engineering & Therapeutics 2018
(2017) Rational antibody humanization assisted by molecular dynamics simulations
Autoren: Schwaigerlehner, L; Pechlaner, M; Mayrhofer, P; Oostenbrink, C; Kunert, R
25th ESACT Meeting 2017
(2017) Complex polymeric IgM produced in Chinese hamster ovary (CHO) cells
Autoren: Hennicke, J; Reinhart, D; Kunert R
9th International Conference on Recombinant Protein Production RPP9 2017
(2017) Rational antibody humanization assisted by molecular dynamics simulations
Autoren: Schwaigerlehner, L; Mayrhofer, P; Pechlaner, M; Oostenbrink, C; Kunert, R
9th International Conference on Recombinant Protein Production RPP9 2017
(2017) IgM/IgA up- and down-stream topics
Autoren: Kunert, R
IgM Tagung
(2017) Transcriptome analysis in high-producing CHO cell cultures: strategies to design high-performing cell culture media
Autoren: Reinhart, D; Castan, C; Damjanovic, L; Ernst, W; Kunert, R
European Society for Animal Cell Technology 2017
(2017) Analyses of product quality of complex polymeric IgM produced by CHO cells
Autoren: Hennicke, J; Reinhart, D; Kunert R
25th ESACT Meeting 2017
(2017) Decision Finding For Production Systems And Expectations For The CHO System
Autoren: Kunert, R; Reinhart, D; Schwaigerlehner, L; Mundsperger, P; Hennicke, J; Sommeregger, W; Mayrhofer, P
BioBrocess Cuba 2017
(2017) Development of DoE based fed-batch strategies for high-producing CHO cell cultures
Autoren: Reinhart, D; Castan, A; Damjanovic, L; Holub, B; Kunert, R
European Society for Animal Cell Technology 2017
(2017) Antibody humanization strategies complemented with deimmunization for safe biotherapeutics
Autoren: Mayrhofer, P; Schwaigerlehner, L; Hoffmann-Freimüller, C; Geyeregger, R; Kunert, R
BioBrocess Cuba 2017
(2017) Synthesis and vaccine potential of novel oligomannosides against HIV-1
Autoren: Trattnig, N; Pantophlet, R; Mayrhofer, P; Kunert, R, Kosma, P.
VII EFMC International Symposium on Advances in Synthetic and Medicinal Chemistry
(2017) Synthesis and vaccine potential of novel oligomannosides against HIV-1
Autoren: Trattnig, N; Pantophlet, R; Mayrhofer, P; Kunert, R; Kosma, P.
19th European Carbohydrate Symposium 2017
(2017) Synthesis and vaccine potential of novel oligomannosides against HIV-1
Autoren: Trattnig, N; Pantophlet, R; Mayrhofer, P; Kunert, R; Kosma, P.
14th Bratislava Symposium on Saccharides BSS 2017
(2017) Rational antibody humanization assisted by molecular dynamics simulations
Autoren: Schwaigerlehner, L; Mayrhofer, P; Pechlaner, M; Oostenbrink, C; Kunert, R
25th ESACT Meeting 2017
(2017) Production of recombinant glycosylated polymeric IgM antibodies in CHO cells
Autoren: Hennicke, J; Grünwald-Gruber, C; Reinhart, D; Altmann, F; Kunert, R
GlycoBioTec 2017
(2016) AllergoOncology: generation of a canine anti-EGFR anticancer IgE
Autoren: Fazekas, J; Singer, J; Matz, M; Mader, A; Spillner, E; Kunert, R; Jensen-Jarolim, E
Meeting of the European Academy of Allergy and Clinical Immunology 2016
(2016) Investigation of different mAb expression potentials by use of complementary culture methods
Autoren: Schwaigerlehner, L; Mayrhofer, P; Kunert, R
PEGS Europe 2016
(2016) Biphasic cultivation strategy to avoid Epo-Fc aggregation and optimize protein expression
Autoren: Reinhart, D; Kaisermayer, C; Gili, Andreas; Chang, Martina; Aberg, PM; Castan, A; Kunert, R
BioProcess International Conference & Exhibition 2016
(2016) Purification of an aggregation prone protein: challenges and solutions for polymeric IgM production
Autoren: Hennicke, J; Lastin, AM; Reinhart, D; Kunert, R
PEGS Europe 2016
(2016) Synthesis of bacterial mimetics of HIV-1 gp120 glycans
Autoren: Trattnig, N; Pantophlet, R; Mayrhofer, P; Kunert, R; Kosma, P.
28th International Carbohydrate Symposium 2016
(2015) Influence of cell culture media and feed supplements on cell metabolism and quality of IgG produced in CHO K1, CHO-S, and CHO DG44
Autoren: Reinhart, D; Kaisermayer, C; Damjanovic, L; Sommeregger, W; Gili, A; Schafellner, S; Castan, A; Kunert, R
European Society for Animal Cell Technology
(2015) Follow the protein: the secretory pathway of recombinant proteins in Pichia pastoris tracked via live cell microscopy
Autoren: Puxbaum V., Landes N., Maccani A., Kunert R., Gasser B., Mattanovich D.
6th International Conference on Analysis of Microbial Cells at the Single Cell Level 2015
(2015) Tracking secretion of recombinant proteins in Pichia pastoris using live cell microscopy
Autoren: Puxbaum V., Landes N., Maccani A., Kunert R., Gasser B., Mattanovich D.
EMBO/EMBL Symposium Seeing is Believing - Imaging the Processes of Life
(2015) Identification of expression bottlenecks of recombinant polymeric antibody production
Autoren: Reinhart, D; Sommeregger, W; Debreczeny, M; Gludovacz, E; Kunert, R
European Society for Animal Cell Technology
(2015) Follow the protein: the secretory pathway of recombinant proteins in Pichia pastoris tracked via live cell microscopy
Autoren: Puxbaum V., Landes N., Maccani A., Kunert R., Gasser B., Mattanovich D.
6th International Conference on Analysis of Microbial Cells at the Single Cell Level 2015
(2015) Identification of bottlenecks in antibody expression using targeted gene integration
Autoren: Mayrhofer, P; Mader, A; Kratzer, B; Reinhart, D; Steinfellner, W; Sommeregger, W; Kunert, R
24th ESACT 2015 - Cells, Culture, Patients, Products
(2014) Cross-species comparison of recombinant protein secretion in CHO cells and Pichia pastoris
Autoren: Landes, Nils; Maccani, Andreas; Leitner, Christian; Maurer, Michael; Graf, Alexandra; Valli, Minoska; Gruber, Clemens; Modarres, Gerda; Altmann, Friedrich; Gasser, Brigitte; Ernst, Wolfgang; Kunert, Renate; Mattanovich, Diethard
ECB16 2014
(2014) "Model based engineering of Pichia pastoris central metabolism enhances recombinant protein production"
Autoren: Hoppe, Frederik; Schillinger, Harald; Schrafvogl, Rudolf; Hutter, Melanie; Kunert, Renate; Eyer, Kurt; Maurer, Michael
5th International Conference on Biomolecular Engineering (ICBE)
(2014) Versatile RMCE Integration of Different Antibody Variants into Predictable Reference Sites in CHO Cells
Autoren: Mayrhofer, P; Mader, A; Kunert, R
PEGS - Protein and Antibody Engineering Summit 2014
(2014) Advanced clarification of cell culture supernatant by 3M™ Emphaze™ AEX Hybrid Purifier for fast and economic bioprocessing of recombinant proteins
Autoren: Hoppe, Frederik; Schillinger, Harald; Schrafvogl, Rudolf; Hutter, Melanie; Kunert, Renate; Eyer, Kurt and Maurer, Michael
ECB16 2014
(2014) RMCE reference sites – A valuable tool for comparing antibody expression capabilities in CHO cells
Autoren: Mayrhofer, P; Mader, A; Kunert, R
16th European Congress on Biotechnology 2014
(2014) Can225IgG, the first 'caninised' antibody against EGFR is highly effective in mediating tumor cell growth inhibition and phagocytosis in vitro
Autoren: Fazekas, J; Singer, J; Wang, W; Weichselbaumer, M; Matz, M; Mader, A; Steinfellner, W; Meitz, S; Mechtcheriakova, D; Sobanov, Y; Willmann, M; Stockner, T; Spillner, E; Kunert, R; Jensen-Jarolim, E
European-Academy-of-Allergy-and-Clinical-Immunology Congress 2014
(2014) Rosa26 Bacterial Artificial Chromosomes as expression vehicles: A fast and effective way to generate stable high producing CHO cells
Autoren: Sommeregger, W; Gili, A; Zboray, K; Sterovsky, T; Casanova, E; Kunert, R
10th Protein and Antibody Engineering Summit
(2014) Cross-species comparison of recombinant protein secretion in CHO cells and Pichia pastoris
Autoren: Landes, Nils; Maccani, Andreas; Leitner, Christian; Maurer, Michael; Gasser, Brigitte; Ernst, Wolfgang; Kunert, Renate; Mattanovich, Diethard
CHOgenome Workshop 2014
(2013) Characterization of model recombinant monoclonal IgM antibodies produced in CHO-DG44 cell lines
Autoren: Chromikova, V; Mader, A; Phan, T; Steinfellner, W; Landucci, G; Forthal, D; Kunert, R
7th Conference on Recombinant Protein Production RPP7 2013
(2013) Optimization of Recombinant Protein Expression in Chinese Hamster Ovary Cells
Autoren: Sommeregger, W.; Gili, A; Sterovsky, T; Casanova, E.; Kunert, R;
7th Conference on Recombinant Protein Production RPP7 2013
(2013) IgG to IgM class switch: Modification of protein properties by antibody engineering
Autoren: Mader, A; Chromikova, V; Kunert, R
2nd Workshop: The new ParadIgM - IgM from bench to clinic
(2013) Passive anti-EGFR immunotherapy in canine cancer patients - a comparative medicine study
Autoren: Fazekas, J; Singer, J; Wang, W; Weichselbaumer, M; Matz, M; Mader, A; Steinfellner, W; Meitz, S; Mechtcheriakova, D; Sobanov, Y; Stockner, T; Spillner, E; Kunert, R; Jensen-Jarolim, E
World Allergy and Asthma Congress of the European-Academy-of-Allergy-and-Clinical-Immunology and World-Allergy-Organization
(2013) Expression of recombinant IgA antibodies and in-depth cell line characterization
Autoren: Reinhart, D; Sommeregger, W; Debreczeny, M; Gludovacz, E; Kunert, R
European Society for Animal Cell Technology 2013
(2013) Transcriptome study of high and low producing recombinant Chinese hamster ovary cell lines
Autoren: Maccani, A., Tatto, N., Graf, A., Leitner, C., Mattanovich, D., Kunert, R., Ernst, W.
7th Conference on Recombinant Protein Production RPP7 2013
(2013) Powerful expression in Chinese Hamster Ovary cells using bacterial artificial chromosomes: parameters influencing productivity
Autoren: Sommeregger, W; Gili, A; Sterovsky, T; Casanova, E; Kunert, R
23rd ESACT Meeting - Better Cells for Better Health
(2013) Cross-species comparison of recombinant protein secretion in CHO cells and Pichia pastoris
Autoren: Landes, N; Maccani, A; Leitner, C; Maurer, M; Gasser, B; Ernst, W; Kunert, R; Mattanovich, D.
7th Conference on Recombinant Protein Production RPP7 2013
(2012) Human recombinant IgMs: a challenging molecule in mammalian cell expression
Autoren: Mader, A; Kunert, R
15th European Congress on Biotechnology ECB15 2012 - Biocrossroads
(2012) Recombinant IgAs Expressed In CHO Cells: Bottlenecks of Recombinant Cell Lines and Improved Production Strategies
Autoren: Renate Kunert
Protein and Antibody Engineering Summit PEGS Europe 2012
(2012) Characterization of Recombinant IgA Producing CHO Cells
Autoren: Sommeregger, W; Reinhart, D; Kunert, R
4th ÖGMBT Annual Meeting 2012
(2012) Recombinant IgMs expressed in mammalian cells
Autoren: Renate Kunert
FA0804 COST Action Molecular farming 2012 -Plants as a production platform for high value proteins
(2012) Production of recombinant IgMs in mammalian cells
Autoren: Chromikova, V; Mader, A; Steinfellner, W; Kunert, R
4th ÖGMBT Annual Meeting 2012
(2012) Comparison of IgM production in different mammalian cell lines
Autoren: Chromikova, V; Mader, A; Steinfellner, W; Kunert, R
15th European Congress on Biotechnology ECB15 2012 - Biocrossroads
(2011) Serum-free production and purification of two anti-HIV-1 human IgAs
Autoren: Reinhart, D; Weik, R; Kunert, R
3rd ÖGMBT Annual Meeting 2011
(2011) Screening and quantification of human IgMs using BioLayer interferometry
Autoren: Alexander Mader Renate Kunert
The new ParadIgM 2011 - IgM from bench to clinic
(2011) Anti-idiotypic antibody Ab2/3H6 mimicking gp41: a potential HIV-1 vaccine?
Autoren: Renate Kunert Alexander Mader
22nd meeting of the European Society for Animal Cell Technology ESACT 2011
(2011) 3D6 and 4B3: Recombinant expression of two anti-gp41 antibodies as dimeric and secretory IgA
Autoren: Reinhart, D; Weik, R; Kunert, R
22nd meeting of the European Society for Animal Cell Technology ESACT 2011
(2011) Humanization of the plant N-glycosylation pathway for the production of therapeutically relevant proteins
Autoren: Castilho, A., Gattinger, P., Pabst, M., Grass, J., Kunert, R., Strasser, R., Altmann, F., Steinkellner, H
21st International Symposium on Glycoconjugates GLYCO 21, 2011
(2011) Production and Purification of 3D6 and 4B3 as Recombinant Human IgA
Autoren: Reinhart, D; Kunert, R
Annual Meeting EuroNeut-41 2011
(2011) Comparison of CHO host cell lines CHO-DUKX-B11 and CHO-DG44
Autoren: Urszula Puc Christian Leitner Renate Kunert
3rd ÖGMBT Annual Meeting 2011
(2011) Quantitative and qualitative analysis of erythropoietin-Fc production in a high density and glutamine-free adapted CHO cell line.
Autoren: Kumar N., Taschwer M., Hackl M., Bort JA., Pabst M., Grass J., Kunert R., Altmann F., Borth, N.
22nd meeting of the European Society for Animal Cell Technology ESACT 2011
(2011) Expression of pentameric IgMs to evaluate regulatory and environmental factors influencing IgM assembly and secretion
Autoren: Veronika Chromikova Willibald Steinfellner Marion Tschernutter Renate Kunert
3rd ÖGMBT Annual Meeting 2011
(2011) Recombinant human IgMs: Purification, characterization and modification
Autoren: Renate Kunert
The new ParadIgM 2011 - IgM from bench to clinic
(2011) Developing monoclonal IgM-producing CHO cell lines for the purpose of further investigation of the product.
Autoren: Chromikova, V; Steinfellner, W; Tschernutter, M; Kunert, R
3rd ÖGMBT Annual Meeting 2011
(2011) 3D6 and 4B3: Recombinant expression of two anti-gp41 mAbs as dimeric and secretory IgA
Autoren: Reinhart, D; Weik, R; Kunert, R
EUROPRISE Annual Conference 2011
(2011) Next-generation sequencing of the Chinese hamster ovary microRNA transcriptome: identification, annotation and profiling of miRNA as targets for cellular engineering.
Autoren: Hackl, M., Jakobi, T., Blom, J., Doppmeier, D., Brinkrolf, K., Szczepanowski, R., Bernhart, S., Höner zu Siederdissen, C., Bort, JA., Wieser, M., Kunert, R., Jeffs, S., Hofacker, I., Goesmann, A., Pühler, A., Borth, N, Grillari, J.
22nd meeting of the European Society for Animal Cell Technology ESACT 2011
(2011) Recombinant human IgMs: Purification, characterization and modification
Autoren: Renate Kunert
The new ParadIgM 2011 - IgM from bench to clinic
(2010) The next generation of 3D6 and 4B3: Isotype switch of two NNAbs to dIgA and sIgA
Autoren: Reinhart, D; Tschernutter, M; Kunert, R
EuroNeut-41 Discovery Meeting 2010
(2010) Recombinant expression of anti-gp41 antibodies as dimeric and secretory IgA
Autoren: Reinhart, D; Tschernutter, M; Kunert, R
EUROPRISE Annual Conference 2010
(2010) Humanization variants of an anti-idiotypic antibody
Autoren: Renate Kunert, Alexander Mader, Hermann Katinger
Human Antibodies and Hybridomas 2010
(2009) Approaches for humanization of an anti-idiotypic murine monoclonal antibody
Autoren: Alexander Mader, Hermann Katinger, Renate Kunert
21st Meeting of the European Society for Animal Cell Technology ESACT 2009
(2009) Glyco-engineering in plants: production of monoclonal antibodies containing homogeneously β1,4-galactosylated human-type N-glycans.
Autoren: Glössl, J., Strasser, R., Castilho, A., Kunert, R., Altmann, F., Mach, L., Steinkellner, H.
GLYCOBIOLOGY 2009
(2009) Consistent1,4-galactosylation of monoclonal antibodies produced in plants.
Autoren: Castilho, A., Strasser, R., Stadlmann, J., Kunert, R., Gattinger, P., Altmann, F., Mach, L., Steinkellner, H
15th European Carbohydrate Symposium 2009
(2008) A study on the temperature dependency and time course of the cold capture secretion assay.
Autoren: Pichler, J., Hesse, F., Wieser, M., Kunert, R., Galosy, S., Mott, J.E., Borth, N.
11th International Conference Cell Culture Engineering 2008
(2008) Is Yeast or CHO system the superior expression system? A case study with a monoclonal Fab
Autoren: Renate Kunert
Cell Line Development and Engineering 2008
(2008) Influence of different genetic parameters and regulatory sequences on recombinant expression of a monoclonal antibody
Autoren: Renate Kunert, H. Reisinger, W. Steinfellner, B. Stern, H. Katinger
Human Antibodies and Hybridomas 2008
(2008) A study on the temperature dependency and time course of the cold capture secretion assay.
Autoren: Pichler, J., Hesse, F., Wieser, M., Kunert, R., Galosy, S., Mott, J.E., Borth, N.
Cell Culture Engineering
(2007) Characterisation of cell behaviour by flow cytometry.
Autoren: Borth N., Hinterkörner G., Hesse F., Ezzenje K., Matej M., Kunert R., Katinger H.,
20th ESACT Meeting 2007
(2007) Transfection of serum-free CHO cells with chemically defined liposomes
Autoren: Reisinger Hannes, Vorauer-Uhl Karola, Steinfellner Willibald, Wagner Andreas, Katinger Hermann and Kunert Renate
Bioprocess International European Conference 2007
(2007) Characterisation of cell behaviour by flow cytometry.
Autoren: Borth N., Hinterkörner G., Hesse F., Ezzenje K., Matej M., Kunert R., Katinger H.
20th ESACT Meeting 2007
(2007) Prologed bioactivity of nanovesicular protein targeting by enhanced depot effect
Autoren: Strobach, S., Wagner, A., Kunert, R., Katinger, H., Vorauer-Uhl, K.
Bioprocess International European Conference 2007
(2007) Correlation between mitochondria-related fluorescent dyes and the energy metabolism in CHO cells
Autoren: Hinterkörner G., Pichler J., Hesse F., Kunert R., Katinger H., Borth N.
20th ESACT Meeting 2007
(2007) Correlation between mitochondria-related fluorescent dyes and the energy metabolism in CHO cells
Autoren: Hinterkörner G., Pichler J., Hesse F., Kunert R., Katinger H., Borth N.
20th ESACT Meeting 2007
(2007) Correlation between mitochondria-related fluorescent dyes and the energy metabolism in CHO cells.
Autoren: Hinterkörner G., Pichler J., Hesse F., Kunert R., Katinger H., Borth N.
20th ESACT Meeting 2007
(2007) Characterisation of cell behaviour by flow cytometry.
Autoren: Borth N., Hinterkörner G., Hesse F., Ezzenje K., Matej M., Kunert R., Katinger H.
20th ESACT Meeting 2007
(2006) Identification of Physiological Bottlenecks hampering Heterologous Protein Expression in Pichia pastoris by Genomic and Proteomic Analysis
Autoren: Dragosits M, Gasser B, Maurer M, Kunert R and Mattanovich D
3rd Summer School in Proteomic Basics 2006 - Exploring the Diversity of Proteins
(2006) Cell Line Development by Fluorescence Activated Cell Sorting
Autoren: Borth N., Brugger G., Hinterkörner G., Ernst W., Müller D., Hesse F., Kunert R., Katinger H.
Engineering Foundation Cell Culture Engineering X
(2006) In vitro and in vivo characterization of an antiidiotypic antibody variants directed against the HIV-neutralizing mAb 2F5
Autoren: Kunert, R., Gach, J., Preis, S., Löschel M., Weik, R., Ferko, B., Stiegler, G., Gasser, B., Mattanivich, D., Katinger, H.
Human Antibodies and Hybridomas 2006
(2006) High level expression of a humanised Ab2/3H6 Fab in Pichia pastoris.
Autoren: Gach, J.,Maurer, M., Quendler, H., Gasser, B., Löschel, M., Mattanovich, D., Katinger, H., Kunert, R.
Recombinant Antibodies
(2006) Biphasic cultivation - A simple strategy to improve the space-time yield of CHO based bioprocesses without affecting product quality
Autoren: Müller, D.
Post Translational Modifications
(2006) Encapsulation efficiency of lipid nano-vesicles for recombinant human Erythropoietin as a model protein
Autoren: Strohbach,St., Wagner,A., Kunert,R., Katinger,H., Vorauer-Uhl, K.
ILS 2006 Annual Meeting
(2006) Serum-free transfections of CHO-cells with defined Small Unilamellar Vesicles
Autoren: Reisinger, H., Vorauer-Uhl, K., Wagner, A., Katinger, H., Kunert, R.,
Cell Line Development and Engineering 2006
(2006) Encapsulation efficiency of lipid nano-vesicles for recombinant human Erythropoietin as a model protein
Autoren: Strohbach,St., Wagner,A., Kunert,R., Katinger,H., Vorauer-Uhl, K.
ILS 2006 Annual Meeting
(2005) Product characterization of a recombinant glycoprotein by isoelectric focusing (Poster)
Autoren: Schriebl, K., Trummer, E., Lattenmayer, C., Müller, D., Hesse, F., Kunert, R., Katinger, H., Vorauer-Uhl, K.
19th ESACT Meeting 2005 - Cell Technology for Cell Products
(2005) Protein biopharmaceuticals from mammalian cell technology: from gene ti the master cell bank
Autoren: Renate Kunert, Willibald Steinfellner, Martina Löschel, Dethardt Müller, Christine Lattenmayer, Sonja Preis, Johannes Gach, Susanne Wolbank, Regina Voglauer, Hermann Katinger
60 Year Anniversary, Institute of Applied Microbiology IAM 2005
(2005) Analysis of genetic parameters in order to get more information on high producing recombinant CHO cell lines (Poster)
Autoren: Lattenmayer, C., Loeschel, M., Schriebl, K., Trummer, E., Vorauer-Uhl, K., Müller, D., Katinger, H., Kunert, R.
19th ESACT Meeting 2005 - Cell Technology for Cell Products
(2005) Improvement of the glycolytic metabolism in mammalian cells by fluorescence activated cell sorting
Autoren: Gudrun Brugger, Dethardt Müller, Renate Kunert, Friedemann Hesse, Hermann Katinger, Nicole Borth
60 Year Anniversary, Institute of Applied Microbiology IAM 2005
(2005) From gene to monoclonal antibody: efficient screening by cell sorting
Autoren: Borth N., Böhm E., Grillari J., Löscher M., Gross S., Voglauer R., Ferko B., Kunert R., Katinger H.
Animal Cell Technology meets Genomics
(2005) Transcription profile analysis of different recombinant CHO clones based on cross species microarray analysis (Poster)
Autoren: Trummer, E., Ernst, W., Müller, D, Schriebl, K., Lattenmayer, C., Kunert, R., Vorauer-Uhl, K., Katinger, H., Hesse, F.
19th ESACT Meeting 2005 - Cell Technology for Cell Products
(2005) Improvement of the glycolytic metabolism in mammalian cells by fluorescence activated cell sorting
Autoren: Borth N., Brugger G., Müller D., Hesse D., Kunert R., Katinger H.
19th ESACT Meeting 2005 - Cell Technology for Cell Products
(2005) Anti-idiotypic antibodies, an alternatve strategy against HIV-1
Autoren: Johannes Gach, Boris Ferko, Brigitte Gasser, Diethardt Mattanovich, Hermann Katinger, Renate Kunert
60 Year Anniversary, Institute of Applied Microbiology IAM 2005
(2005) Protein Biopharmaceuticals from Mammalian Cell Technology: from the Gene to the Master Cell Bank
Autoren: Rnate Kunert
60 Year Anniversary, Institute of Applied Microbiology IAM 2005
(2005) From Gene to antibody: efficient screening by cell sorting.
Autoren: Ernst Böhm, Johannes Grillari, Martina Löschel, Stefan Gross, Regina Voglauer, Renate Kunert, Hermann Katinger, Nicole Borth
60 Year Anniversary, Institute of Applied Microbiology IAM 2005
(2005) Protein free transfection of CHO host cells with and IgG-fusion protein – selection and characterisation of stable high producers
Autoren: Christine Lattenmayer, Martina Löschel, Evelyn Trummer, Karola Vorauer-Uhl, Hermann Katinger, Renate Kunert
60 Year Anniversary, Institute of Applied Microbiology IAM 2005
(2005) Sorting for high producers: Methods and application
Autoren: Ernst Böhm, Max Zeyda, Willibald Steinfellner, Regina Voglauer, Renate Kunert, Hermann Katinger, Nicole Borth
60 Year Anniversary, Institute of Applied Microbiology IAM 2005
(2005) Effect of pH, DO and Temperature on the Performance of CHO Cells in a Batch Process (Poster)
Autoren: Trummer, E., Hesse, F., Seidinger, S., Fauland, K., Schriebl, K., Lattenmayer, C., Borth, N., Kunert, R., Vorauer-Uhl, K., Katinger, H., Müller, D.,
19th ESACT Meeting 2005 - Cell Technology for Cell Products
(2005) Protein biopharmaceuticals from mammalian cell technology: from the gene to the master cell bank
Autoren: Kunert, R., Steinfellner, W., Löschel, M., Müller, D., Lattenmayer, C., Preis, S., Gach, J., Wolbank, S., Voglauer, R., Katinger, H.
60 Year Anniversary, Institute of Applied Microbiology IAM 2005
(2005) Anti-idiotypic antibodies an alternative strategy against HIV-1
Autoren: Gach, J., Ferko, B., Gasser, B., Mattanovich, D., Katinger, H., Kunert, R.
60 Year Anniversary, Institute of Applied Microbiology IAM 2005
(2005) Optimisation of protein secretion in antibody fragment expressing Pichia pastoris
Autoren: Gasser B., Maurer M., Kunert R., Mattanovich D.
60 Year Anniversary, Institute of Applied Microbiology IAM 2005
(2005) Protein Free Transfection of CHO Host Cells with an IgG-Fusion Protein - Selection and Characterisation of Stable High Producers (Poster)
Autoren: Christine Lattenmayer, Martina Loeschel, Evelyn Trummer, Karola Vorauer-Uhl, Hermann Katinger, Renate Kunert
7th Conference on Protein Expression in Animal Cells PEACe 2005
(2005) Characterisation of CHO Subclones Showing Profound Changes in Performance when Propagated in Different Cultivation Systems (Poster)
Autoren: Trummer, E., Steinfellner, W., Kunert, R., Steindl, F., Hesse, F., Katinger, H., Müller, D.
60 Year Anniversary, Institute of Applied Microbiology IAM 2005
(2004) Anti-idiotypic antibody, Ab2b-3H6, against the neutralizing anti-HIV-antibody mimics the conserved env-epitope ELDKWA
Autoren: Gach, J., Preis, S., Steinfellner, W., Löschel, M., Weik, R., Ferko, B., Stiegler, G., Katinger, H. and Kunert, R.
Human Antibodies and Hybridomas 2004
(2004) Comparison of protein profiles of different CHO cell lines
Autoren: Przewalla, C., Chang, M., Kunert, R., Hesse, F., Grillari, J., Borth, N., Katinger, H.
6th Siena meeting from genome to proteome 2004 - Biomarker discovery and proteome imaging
(2004) Effect of class switches of anti-HIV neutralizing mAbs expressed in CHO cells as IgG3, IgG1, IgM and IgA
Autoren: Kunert,R., Wolbank,S., Vorauer-Uhl,K., Stiegler,G., Vcelar,B., Katinger,H.
Cell Culture and Upstream Processing
(2004) Effect of increased levels of Protein Disulfide Isomerase and BiP/GRP78 on human antibody productivity in recombinant CHO cells
Autoren: Borth N, Mattanovich D., Kunert R, Katinger H.
Cell Culture Engineering IX, Engineering Foundation Conference
(2003) Comparison of fluidized bed and fed-batch reactor cultures for production of anti-HIV antibody
Autoren: Hinterleitner, P., Unterluggauer, F., Landauer, K., Müller, D., Kunert, R., Blüml, G., Doblhoff-Dier, O., Katinger, H.
18th ESACT Meeting 2003 - Animal Cell Technology Meets Genomics
(2003) Control of Key Parameters in the Development of mammalian production clones
Autoren: Kunert R., Preis S., Steinfellner W., Assadian A., Borth N., Müller D., Katinger H.
18th ESACT Meeting 2003 - Animal Cell Technology Meets Genomics
(2003) Efficient Selection of Antigen Specific Hybridomas by Cell Sorting using a Single Cell Secretion Assay
Autoren: Borth N., Böhm E., Grillari J., Voglauer R., Kunert R., Gross S., Ferko B., Katinger H.
18th ESACT Meeting 2003 - Animal Cell Technology Meets Genomics
(2003) Characterisation of CHO subclones showing profound changes in performance when propagated in different cultivation systems
Autoren: Trummer, E., Müller, D., Steinfellner, W., Kunert, R., Steindl, F., Hesse, F., Katinger, H
18th ESACT Meeting 2003 - Animal Cell Technology Meets Genomics
(2003) From gene to monoclonal antibody: efficient screening by cell sorting
Autoren: Borth, N., Böhm, E., Grillari, J., Löscher, M., Gross, S., Voglauer, R., Ferko, B., Kunert, R., Katinger, H.
18th ESACT Meeting 2003 - Animal Cell Technology Meets Genomics
(2003) Effiziente Selektion von hochproduzierenden tierischen Zelllinien für die Produktion von biopharmazeutischen Produkten mit dem Zellsorter
Autoren: Borth N., Böhm E., Voglauer R., Kunert R., Katinger H.
Jahrestagung der Österreichischen Geselschaft für Flow Zytometrie
(2002) Efficient Selection of monoclonal, antigen-specific and high-producing Hybridoma Cell Lines in a Single Cloning Step by Flow Cytometry and Cell Sorting.
Autoren: Böhm, E., Borth, N., Voglauer, R., Stiegler, G., Hahn, R., Ferko, B., Kunert, R., Katinger, H.
UEF Cell Culture Engineering Conference
(2002) Efficient selection of monoclonal, antigen-specific and high-producing hybridoma cell lines by flow cytometry and cell sorting: in a single cloning step ?
Autoren: Böhm, E., Borth, N., Voglauer, R., Kunert, R., Ferko, B., Wiederkum, S., Stiegler, G., Hahn, R., Katinger, H.
ISAC 2002 XXI Congress of the International Society for Analytical Cytology
(2002) Expression von Glykoproteinen in rekombinanten CHO-Zellen
Autoren: R. Kunert, D. Müller, N. Borth, R. Weik, H. Katinger
Österreichische Gesellschaft für Zellkultur und European Tissue Culture Society: Neues aus der Zell- und Gewebekultur
(2002) Establishment of human cell lines expressing human Erythropoietin.
Autoren: Voglauer, R., Kunert, R., Steinfellner, W., Katinger, H.
Joint annual meeting of the Österreichische Gesellschaft für Biotechnologie ÖGBM, ÖGGGT, ÖGBT and ANGT 2002
(2002) Screening for Additional Cell Properties: Selection of Subclones with Altered Production Kinetics or Improved Stability by Cell Sorting using an Affinity Matrix Secretion Assay
Autoren: Borth, N., Böhm, E., Voglauer, R., Steinfellner, W., Kunert, R., Katinger, H.
UEF Cell Culture Engineering Conference
(2002) Antibody secreting cell lines as model systems for affinity matrix secretion assay based cell sorting.
Autoren: Böhm, E., Voglauer, R., Kunert, R., Grillari, J., Gross, S., Ferko, B., Katinger, H., Borth, N.
15th Heidelberg Cytometry Symposium (HCS) Annual Meeting of the German Society of Cytometry (DGfZ)
(2002) Mouse/human anti-idiotypic antibodies and chimeric fusion proteins mimicking neutralizing HIV-antigens (Poster)
Autoren: Christine Lattenmayer, Renate Kunert, Sonja Preis, Gabriela Stiegler, Robert Weik, Boris Ferko, Hermann Katinger
2nd International conference on Recombinant protein production 2002 - A comparative view on host physiology
(2001) Die Entwicklung klinischer Biopharmaka mittels nativer und rekombinanter Eukaryonten
Autoren: Kunert,R., Vorauer-Uhl,K., Borth,N., Katinger,H.
Hochschullehrer-Nachwuchstreffen der DECHEMA
(2001) Continuous Perfusion versus Discontinous Fed-Batch (oral presentation)
Autoren: Müller, D., G. Simic, W. Steinfellner, R. Keijzer, R. Kunert, E. Benes, M. Gröschl, F. Trampler, O. Doblhoff-Dier and H. Katinger
17th ESACT Meeting 2001. Animal Cell Technology: From Target to Market
(2001) Efficient and Rapid Clone Selection of Human-Antibody Producing Xenohybridomas by Flow Cytometry and Cell Sorting According to Single Cell Specific Production Rate.
Autoren: Böhm, E., Borth, N., Voglauer, R., Wiederkum, S., Kunert, R., Katinger, H.
Human Antibodies and Hybridomas 2001
(2000) Maintenance of a high antibody expression level in CHO cells without selective and amplification pressure by cell sorting
Autoren: Böhm, E., Borth, N., Voglauer, R., Kunert, R., Steinfellner, W., Katinger, H.
ISAC congress XX
(2000) Analysis of oncogene expression and chromosomal stability of SV40 early region transfected (ISAC congress XX,
Autoren: Voglauer, R., Kunert, R., Hohenwarter, O., Böhm, E., Borth, N., Katinger, H.
ISAC congress XX
(1999) Analysis of genomic DNA and RNA-Transcripts of a heterohybridoma simultanously expressing IgG3 and IgG1 with identical specificity.
Autoren: Kunert, R., S. Wolbank, A. Hüser and H. Katinger
16th ESACT-Meeting 1999. Animal Cell Technology: Products from Cells, Cells as Products
(1999) Stable recombinant expression and functional identity of the antio HIV-1 monoclonal antibody 2F5 after IgG3/IgG1 subclass switch in CHO-cells
Autoren: Kunert, R., W. Steinfellner, A. Assadian and H. Katinger
16th ESACT-Meeting 1999. Animal Cell Technology: Products from Cells, Cells as Products
Process intensification through cell culture perfusion
Autoren: Mayrhofer, P; Kunert, R
Control of key parameters in the development of mammalian production clones
Autoren: R. Kunert, S. Wolbank, D. Müller, R. Voglauer, N. Borth, H. Katinger
Bacterial Artificial Chromosomes as expression vehicles for improved protein expression
Autoren: Sommeregger, W; Gili, A; Zboray, K; Sterovsky, T; Casanova, E; Kunert, R
Benchmarking of commercially available CHO cell culture media for antibody production
Autoren: Reinhart, D; Damjanovic, L; Kunert, R
Perfusion media development for scalable processes
Autoren: Mayrhofer, P; Kunert, R
Analysis of energy metabolism in recombinant CHO cells by flow cytometric methods
Autoren: Borth N., Brugger G., Müller D., Hesse F., Kunert R., Katinger H.
High Level Expression of a Humanised Ab2/3H6 Fab in Pichia Pastoris.
Autoren: Gach, J., Maurer, M., Quendler, H., Gasser, B., Löschel, M., Mattanovich, M., Katinger, H., Kunert, R.
Genetic Determination of Recombinant Expression Clones under Serum Containing and Serum Free Cultivation Conditions (Poster)
Autoren: Lattenmayer, C., Löschel, M., Schriebl, K., Kunert, R., Katinger, H.,
Does CHO gene expression change in response to expressed mAb variant?
Autoren: Schwaigerlehner, L; Akhtar, S; Scholey, R; Torres, M; Mayrhofer, P; Dickson, AJ; Kunert, R
Maintenance of a high antibody expression level in recombinant CHO cells without selective and amplification pressure by cell sorting.
Autoren: Borth, N., Böhm, E., Voglauer, R., Kunert, R., Steinfellner, W., Katinger, H.
Establishment of recombinant CHO for industrial protein production
Autoren: R.Kunert, K.Strutzenberger, F.Steindl, G.Vecera, A.Zudjelovic, N.Borth, H.Katinger
In search of bottlenecks of recombinant IgA antibody expression
Autoren: Reinhart, D; Sommeregger, W; Debreczeny, M; Gludovacz, E; Kunert, R
Benchmarking of commercially available CHO cell culture media for antibody production
Autoren: Reinhart, D; Kaisermayer, C; Damjanovic, L; Kunert, R
Genetic determination of recombinant protein expression clones under serum free cultivation conditions
Autoren: Lattenmayer C., Löschel M., Borth N., Kunert R., Katinger H.
Protein Engineering and Process Mode for Successful Production of the Extracellular Domain of CD19
Autoren: Kunert, R; Mayrhofer, P;
Transient gene expression for evaluation of antibody humanization by molecular dynamics simulation
Autoren: Mayrhofer, P; Mader, A; Margreitter, C; Oostenbrink, C; Kunert, R
EVALUATION OF C1q BINDING AND COMPLEMENT ACTIVATION OF NEW RECOMBINANT HUMAN IGMS AS QUALITY PRODUCTION ATTRIBUTES
Autoren: Reiser, JB; Hennicke, J; Bally, I; Chouquet, A; Ling, WL; Reinhart, D; Altmann, F; Kunert, R; Thielens, N