Career
- 2000 degree, University of Vienna
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Lectures
(2016) Mechanism of hydrogen peroxide to dioxygen oxidation by bifunctional catalase-peroxidase
Autoren: Obinger, C., Jakopitsch, C., Furtmüller, P. G., Gasselhuber, B., Zamocky, M
79th Harden Conference on Oxygen Evolution and Reduction - Common Principles
(2016) Two redox active cofactors are essential for the catalatic activity of catalase-peroxidases
Autoren: Jakopitsch, C., Gasselhuber, B., Furtmüller, P. G., Obinger, C.
13th European Biological Inorganic Chemistry Conference EuroBIC 2016
(2015) The peroxidase-cyclooxygenase superfamily - evolution of structure and function
Autoren: Obinger, C; Paumann-Page, M; Auer, M; Nicolussi, A; Zamocky, M; Jakopitsch C; Furtmüller P.G;
9th International Human Peroxidase Meeting 2015
(2015) Interactions of hydrogen sulfide with myeloperoxidase
Autoren: Palinkas, Z; Furtmuller, PG; Nagy, A; Jakopitsch, C; Pirker, KF; Magierowski, M; Jasnos, K; Wallace, JL; Obinger, C; Nagy, P
3rd European Conference on the Biology of Hydrogen Sulfide (H2S)
(2015) Recombinant production, biochemical and structural investigation of a eukaryotic bifunctional catalase-peroxidase
Autoren: Gasselhuber, B., Nicolussi, A., Carpena, X., Zamocky, M., Jakopitsch, C., Furtmüller, P.G., Fita, I., Obinger, C.
8th Conference on Recombinant Protein Production RPP8 2015
(2014) Hydrogen sulfide functions as reversible inhibitor and electron donor for human myeloperoxidase
Autoren: Pirker, KF; Palinkas, Z; Furtmuller, PG; Nagy, A; Jakopitsch, C; Obinger, C; Nagy, P
12th European Biological Inorganic Chemistry Conference EuroBIC 2014
(2014) Understanding the inhibition mechanism of chlorite dismutase from the nitrite-oxidizing bacterium Candidatus Nitrospira defluvii
Autoren: Hofbauer, S; Gruber, C; Schaffner, I; Pirker, KF; Jakopitsch, C; Sundermann, A; Oostenbrink, C; Furtmuller, PG; Obinger, C
12th European Biological Inorganic Chemistry Conference EuroBIC 2014
(2014) Mechanism of reaction of chlorite with mammalian peroxidases
Autoren: Jakopitsch, C; Pirker, KF; Flemmig, J; Hofbauer, S; Schlorke, D; Furtmuller, PG; Arnhold, J; Obinger, C
12th European Biological Inorganic Chemistry Conference EuroBIC 2014
(2014) Investigating the relation between structure and reaction mechanism of eukaryotic catalase-peroxidase
Autoren: Gasselhuber, B; Nicolussi, A; Carpena, X; Zamocky, M; Jakopitsch, C; Furtmuller, PG; Fita, I; Obinger, C
12th European Biological Inorganic Chemistry Conference EuroBIC 2014
(2014) Interactions of hydrogen sulfide with human myeloperoxidase.
Autoren: Pirker, KF; Palinkás, Z; Furtmüller, PG; Nagy, A; Jakopitsch, C; Obinger, C; Nagy, P
Gordon Research Conference "Oxygen Radicals"
(2012) Human peroxidasin 1 – Phylogeny and preliminary characterization of a peculiar multidomain protein
Autoren: Soudi, M., Zamocky, M., Jakopitsch, C., Furtmüller, P.G., and Obinger, C.
9th International Conference on Protein Stability 2012 - From molecular level to market applications
(2012) Reaction of heme peroxidases with chlorite
Autoren: Jakopitsch, C. Furtmüller, P.G. & Obinger, C.
OxiZymes 2012
(2012) The peroxidase-cyclooxygenase superfamily - phylogeny, structure and function
Autoren: Obinger, C. Soudi, M. Auer, M. Zamocky, M. Jakopitsch C. and Furtmüller P.G.
OxiZymes 2012
(2012) Human peroxidasin 1 - phylogenetic analysis and characterization of a perculiar multidomain protein
Autoren: Soudi, M. Zamocky, M. Jakopitsch., C. Delporte, C. Van Antwerpen, P. Furtmüller, P.G. & Obinger, C.
OxiZymes 2012
(2011) Modulation of heme reactivity of peroxidases by autocatalytic posttranslational modifications
Autoren: Obinger, C., Stampler, J., Vlasits, J., Furtmüller, P. G., Smulevich, G., Battistuzzi, G.
International Conference on Bioinorganic Chemistry ICBIC-15 2011
(2010) From chemistry of bifunctional catalase-peroxidases towards molecular evolution of the peroxidase-catalase superfamily
Autoren: Zamocky, M., Motz, M., Furtmüller, P. G., Vlasits, J., Jakopitsch, C., Obinger, C.
5th Central European Conference on Chemistry meets biology
(2010) Mechanism of hydrogen peroxide oxidation in catalase-peroxidases
Autoren: Jakopitsch, C., Vlasits, J., Obinger, C.
5th Central European Conference on Chemistry meets biology
(2010) Mechanisms of catalase activity of heme peroxidases: from pseudo-catalatic activity in monofunctional peroxidases to high catalase activity in bifunctional catalase-peroxidases
Autoren: Vlasits, J., Jakopitsch, C., Motz, M., Zamocky, M., Furtmüller, P.G., Obinger, C.
OxyZymes & 9th International Meeting on Peroxidases 2010
(2008) The peroxidase-cyclooxygenase superfamily
Autoren: Obinger, C., Jakopitsch, C., Furtmüller, P.G., Zamocky, M.
26th Congress of the Federation of European Societies of Plant Biology FESPB 2008 tohether with 11th annual international meeting for experimental moss research and 8th International Peroxidase Symposium, Peroxidase 2008
(2007) Evolutionary history of human peroxidases
Autoren: Zamocky, M., Dunand, C., Furtmüller, P.G., Jakopitsch, C., Obinger, C.
5th International Conference on Human Peroxidases 2007
(2006) Probing the reaction of three distinct catalase-peroxidases with peroxides
Autoren: Jakopitsch, C., Wiseman, B., Vlasits, J., Obinger, C.
Peroxidase Meeting 2006
(2006) Identification of the unique site (Trp106) for the formation of the [Fe(IV)=O Trp.] intermediate in Synechocystis PCC6803 KatG and the (distal heme side) extended H-bonding network with a crucial role in catalase activity vy using multifrequency (9-285 GHz) EPR spectroscopy
Autoren: Jakopitsch, C., Obinger, C., Un, S., Ivancich, A.
8th European Biological Inorganic Chemistry Conference EuroBIC 2006
(2006) Trapping the spectral features of the redox intermediates in the catalatic cycle of catalase-peroxidase
Autoren: Jakopitsch, C., Vlasits, J., Obinger, C.
8th European Biological Inorganic Chemistry Conference EuroBIC 2006
(2006) Investigation of the catalytic mechanism of Synechocystis catalase-peroxidase with doubly O18-labeled hydrogen peroxide
Autoren: Vlasits, J., Jakopitsch, C., Holubar, P., Obinger, C.
8th European Biological Inorganic Chemistry Conference EuroBIC 2006
(2006) Redox thermodynamics of the Fe(III)/Fe(II) couple in wild-type heme peroxidases and in their CN-adducts
Autoren: Bellei, M., Jakopitsch, C., Battistuzzi, G., Sola, M., Obinger, C.
Peroxidase Meeting 2006
(2006) The catalatic activity of monofunctional catalases and bifunctional catalase-peroxidases follows different mechanisms
Autoren: Obinger, C., Vlasits, J., Jakopitsch, C.
8th European Biological Inorganic Chemistry Conference EuroBIC 2006
(2006) Structure and function of peroxidases from the lactoperoxidase superfamily
Autoren: Obinger, C., Zederbauer, M., Stampler, J., Jakopitsch, C., Furtmüller, P. G.
Peroxidase Meeting 2006
(2006) Detoxification of hydrogen peroxide in cyanobacteria
Autoren: Bernroitner, M., Jakopitsch, C., Obinger, C.
Peroxidase Meeting 2006
(2005) Probing the role of the peculiar Trp-Tyr-Met adduct in the heme pocket of bifunctional catalase-peroxidases
Autoren: Jakopitsch, C., Vlasits, J., Ivancich, A., Obinger, C.
Life Sciences 2005, Joint Annual Meeting of ÖGBM, ÖGGGT, ÖGBT and ANGT
(2005) Spectral and kinetic studies on redox intermediates in heme peroxidases from both superfamilies
Autoren: Obinger, C., Furtmüller, P.G., Zederbauer, M., Jakopitsch, C.
First European Conference on Chemistry for Life Sciences
(2005) The role of selected residues in the heme architecture of catalase-peroxidases
Autoren: Droghetti, E., Jakopitsch, C., Obinger, C., Smulevich, G.
The VII Conference on Plant Peroxidases
(2005) The role of the unusual crosslinked distal site Trp-Tyr-Met adduct in catalysis of bifunctional catalase-peroxidase
Autoren: Jakopitsch, C., Vlasits, J., Ivancich, A., Obinger, C.,
1st European Conference on Chemistry for Life Sciences 2005
(2004) Redox Intermediates of human heme peroxidases: a comparative mutational and kinetic study .
Autoren: Furtmüller, P. G., Jantschko, W., Zederbauer, M., Jakopitsch, C., Arnhold, J., Obinger, C.
2nd European Conference on Chemistry towards Biology 2004
(2004) Kinetics of interconversion of redox intermediates of lactoperoxidase, eosinophil peroxidase and myeloperoxidase
Autoren: Obinger, C., Jantschko, W., Zederbauer, M., Jakopitsch, C., Furtmüller, P. G.
4th International Peroxidase Meeting 2004
(2004) Towards understanding the catalatic activity of peroxidases and catalases?
Autoren: Jakopitsch, C., Schmuckenschlager, F., Zehner, F., Wanasinghe, A., Furtmüller, P. G., Obinger, C.
COST Chemistry Action D21
(2004) Reactivity of ferrous heme peroxidases from both superfamilies with hydrogen peroxide and molecular oxygen
Autoren: Jantschko, W., Furtmüller, P. G., Zederbauer, M., Jakopitsch, C., Obinger, C.
COST Chemistry Action D21
(2004) Insights into catalase-peroxidase by electronic absorption, resonance Raman spectroscopy, and site-directed mutagenesis
Autoren: Smulevich, G., Santoni, E., Jakopitsch, C., Obinger, C.
3rd International Conference on Porphyrins and Phthalocyanines (ICPP-3) 2004
(2003) Comparison between catalase-peroxidase and cytochrom c peroxidase: A resonance raman study
Autoren: Santoni, E., Jakopitsch, C., Obinger, C., and Smulevich, G.
Metalloenzymes and Chemical Biometics 2003
(2003) Engineering catalase-peroxidases: The structural basis of the activity of catalase-peroxidases.
Autoren: Petutschnig, G., Jakopitsch, C., Auer, M., Rüker, F., Furtmüller, P. G., and Obinger, C.
Eigth International Summer School on Biophysics
(2003) Do we really understand the catalatic reactivity?
Autoren: Jakopitsch, C; Petutschnig, G; Zehner, F; Ruker, F; Furtmuller, PG; Obinger, C
Plant Stress, Reactive Oxygen and Antioxidants
(2003) Identification of the radical intermediates formed by the catalase-peroxidase of Synechocystis PCC6803: A multifrequency EPR spectroscopy study combined with isotope labelling and site directed mutagenese
Autoren: Ivancich, A., Jakopitsch, C., and Obinger, C.
Metalloenzymes and Chemical Biometics 2003
(2002) Understanding the Heme Cavity of Catalase-Peroxidase via Site-Directed Mutagenesis and Resonance Raman Spectroscopy
Autoren: Smulevich, G., Santoni, E., Heering, H. A., Indiani, C., Jakopitsch, C., Regelsberger, G., and Obinger, C.
6th European Biological Inorganic Chemistry Conference EuroBIC 2002
Binding of peroxides and inhibitors to the active site of catalase-peroxidases.
Autoren: Jakopitsch, C., Regelsberger, G., Rüker, F., Peschek, G.A., Obinger, C.
Probing active site residues of catalase-peroxidases.
Autoren: Jakopitsch, C., Regelsberger, G., Rüker, F., Peschek , G.A., Obinger, C.
Hydroperoxidases in oxygenic phototrophic prokaryotes- comparison to plant chloroplasts
Autoren: Regelsberger, G., Jakopitsch, C., Rücker, F., Peschek, G.A., Obinger, C.
Chlorite as oxidant and reductant of heme peroxidases: a mechanistic study
Autoren: Furtmüller, P.G., Jakopitsch, C., Spalteholz, H., Arnhold, J., Obinger, C.
Catalase versus peroxidase activity. Towards understanding the bifunctional activity of catalase-peroxidases.
Autoren: Regelsberger, G., Jakopitsch, C., Rüker, F., Loewen, P., Peschek, G. A., Obinger, C.
Manipulating the distal asparagine-histidine couple in catalase-peroxidase.
Autoren: Jakopitsch, C., Regelsberger, G., Rücker, F., Peschek, G.A., Obinger, C.
Mechanism of reaction of human peroxidases with nitrite and peroxynitrite.
Autoren: Obinger, C., Furtmüller, P.G., Jantschko, W., Zederbauer, M., Jakopitsch, C., Herold, S., Koppenol, W.H.
Mechanism of inhibition of chlorite dismutase
Autoren: Hofbauer, S., Schaffner, I., Gruber, C., Pirker, K.F., Jakopitsch, C., Sündermann, A., Oostenbrink, C., Furtmüller, P.G., Obinger, C.
Catalase versus peroxidase activity. Towards understanding the bifunctional activity of catalase-peroxidases.
Autoren: Regelsberger, G., Jakopitsch, C., Rüker, F., Peschek, G.A., Switala, J., Loewen, P., Obinger, C.
Interactions of hydrogen sulfide with human myeloperoxidase
Autoren: Pirker, K.F., Pálinkás, Z., Furtmüller, P.G., Nagy, A., Jakopitsch, C., Obinger, C., Nagy, P.
Redox thermodynamic of the Fe3+/Fe2+ couple in wild-type and mutated heme peroxidases
Autoren: Battistuzzi, G., Bellei, M., Jakopitsch, C., Vlasits, J., Furtmüller, P.G., Sola, M., Obinger, C.
Looking for peroxidase substrates and binding site(s) in bifunctional catalase-peroxidase
Autoren: Vlasits, J., Zamocky, M., Jakopitsch, C., Obinger, C.
Fungal catalase-peroxidases - a novel group of bifunctional oxidoreductases
Autoren: Zamocky, M., Jakopitsch, C., Vlasits, J., Obinger, C.
Molecular engineering of catalase-peroxidases.
Autoren: Jakopitsch, C., Regelsberger, G., Rüker, F., Peschek, G.A., Obinger, C.
Redox thermodynamic of the Fe3+/Fe2+ couple in wild-type and mutated heme peroxidases
Autoren: Battistuzzi, G., Bellei, M., Jakopitsch, C., Vlasits, J., Furtmüller, P.G., Sola, M., Obinger, C.
Binding of peroxides and inhibitors to the active site of catalase-peroxidases.
Autoren: Jakopitsch, C., Regelsberger, G., Rüker, F., Peschek, G.A., Obinger, C.
Chlorite inactivates mammalian peroxidases
Autoren: Jakopitsch, C., Pirker, K.F., Flemmig, J. Hofbauer, S., Furtmüller, P.G., Schlorke, D., Arnhold, J., Obinger, C.
The molecular and functional peculiarities of class I peroxidases.
Autoren: Obinger, C., Regelsberger, G., Jakopitsch, C., Peschek, G.A., Rüker, F.
Bifunctional eucaryotic catalase-peroxidase - investigating the relation between structure and reaction mechanism
Autoren: Gasselhuber, B., Nicolussi, A., Carpena, X., Zamocky, M., Jakopitsch, C., Furtmüller, P.G., Fita, I., Obinger, C.
The role in the stability of the heme architecture of selected catalase-peroxidase mutants. An overview of a spectroscopic study.
Autoren: Droghetti, E., Jakopitsch, C., Obinger, C., Smulevich, G
The catalatic acitivity of catalase-peroxidases.
Autoren: Jakopitsch, C., Regelsberger, G., Rüker, F., Peschek, G.A., Obinger, C.