Glycan structure and biosynthesis in Entamoeba histolytica

The major aims of this project are related to galactose in Entamoeba histolytica in terms of its metabolism and incorporation into glycoconjugates, whereby galactose is a known component of the cell surface lipopeptidophosphoglycan (LPPG) as well as of N-glycans. However, other than the predicted occurrence of UDP-galactose epimerase, there is currently little information regarding galactose metabolic and transfer reactions in this parasite.