Danube Allergy Research Cluster – Towards the cure of allergy
Abstract
IgE-associated allergy affects more than 30% of the population and hence is the most common immunologically mediated hypersensitivity disease. The hallmark of allergy is the formation of IgE antibodies against per se innocuous antigens (i.e., allergens) in allergic patients. IgE-allergen immune complexes trigger immediate symptoms of allergic inflammation. The unique feature of this research program is the focus on the molecular characterization of the disease-causing allergens. Clinically relevant allergens will be used to study the mechanisms of allergy in patients, to establish tools for molecular diagnosis and for the investigation of the evolution of allergy in early childhood, to investigate avoidance and vaccination strategies for personalized treatment in the sense of precision medicine and most importantly, to develop allergen-specific prevention strategies such as man-made-reduction of allergen exposure, prophylactic vaccination strategies, and preventive tolerance induction using novel vectors, adjuvants, oral tolerance induction and cell-based strategies. The “Danube Allergy Research Cluster (Danube-ARC)” is an Allergy Research program consisting of 16 research projects. Scientists from the Medical University of Vienna are teaming up with researchers from the country of Lower Austria, i.e. the Austrian Intitute of Technology (AIT, Tulln), the BOKU Departments of Agrobiotechnology (IFA-Tulln) and Crop Sciences (DNW, Tulln) and the Karl Landsteiner University of Health Sciences (KL, Krems, St.Pölten, Tulln).
allergy food allergens immunoanalytical testsystems plant breeding
Publikationen
A novel wheat allergen chip for analysis of wheat allergen-specific antibody responses
Autoren: Krisai, A; Call, L; Huang, HJ; Schlederer, T; Focke-Tejkl, M; Tulaev, M; Linhart, B; Valenta, R; Grausgruber, H Jahr: 2023
Conference & Workshop proceedings, paper, abstract
Project staff
Sabine Baumgartner
Ao.Univ.Prof. Dipl.-Ing. Dr.nat.techn. Sabine Baumgartner
sabine.baumgartner@boku.ac.at
Tel: +43 1 47654-97314
BOKU Project Leader
14.02.2024 - 30.09.2024
Sub Projectleader
19.12.2023 - 13.02.2024
Project Staff
01.10.2020 - 18.12.2023
Kathrin Lauter
Kathrin Lauter
kathrin.lauter@boku.ac.at
Tel: +43 1 47654-97313, 97356
BOKU Project Leader
01.10.2020 - 13.02.2024
Michael Wiederstein
Michael Wiederstein MSc.
michael.wiederstein@boku.ac.at
Project Staff
01.10.2020 - 30.09.2024