Inactivation of Mycotoxins
Abstract
Mycotoxins are secundary metabolites of fungi and are produced during growth of the microorganisms, e. g. on cereal plants. By that way these toxins may pass into the food-chain and cause severe problems, especially in animal nutrition. Due to their acute toxic and immunsuppressive effects these compounds reduce the productivity and the growth performance of animals which often leads to serious economic losses in animal production. The aim of this project is the development of strategies and applications for the biological inactivation of different classes of mycotoxins, meaning the detoxification of such compounds into non-toxic metabolites via microbial transformation. On that basis, a feed-additive will be developed which aims to detoxify given mycotoxins during the process of feed-digestion in the intestine of the animals. The major aspects of this project include the screening for microorganisms with mycotoxin-transforming potential, physiological and taxonomic characterisation of the same, as well as intensive investigations concerning their degradation-behaviour and the applicability as a feed-additive. Mycotoxin-analysis (HPLC, TLC, ELISA, LC-MS), isolation procedures for microorganisms and identification, screening for toxin-transforming activity, as well as performance of toxicity assays and fermentation will represent different working packages within this project.
feed additive mycotoxins
Publikationen
Project staff
Andreas Paul Loibner
Ao.Univ.Prof. Dipl.-Ing. Dr.nat.techn. Andreas Paul Loibner
andreas.loibner@boku.ac.at
Tel: +43 1 47654-97470
Project Leader
01.10.2003 - 31.12.2009