Bioactive Microbial Metabolites - NÖ
Abstract
Automated high-throughput screening system with downstream phenotyping and genotyping technology Location: Technopol-Tulln Structure: Fee-based shared core facility open to all users (universities, research institutes, fach-hochschulen industry, project consortia, etc) Infrastructure suitable for the following projects (examples): • Investigate the interaction of microbes with cells from other simple or complex organisms (bacteria, fungi, algae, moss, other plant, animal cells) and thus e.g. to identify the production of bioactive substances (new antibiotics, pharmaceuticals, bioeffectors, agroceuticals, etc.) • Study individual microbes under a multitude of environmental and nutritional conditions, and thus identify bio-and agro-technological potential • Test the effect of various environmental stresses (temperature, toxins, UV, etc.) • Study cells of different origin (microbes, plants, insects) in their mutual stimulatory or inhibitory effects in a high-throughput way • Study pathogen interactions or identify organic control species • Screen for biotechnological usable enzymes using "bio-refinery" approaches (in collaboration with AGs cellulose chemistry, energy crops) Infrastructure: • Automated liquid handling (ALH) system for the cultivation / growth tests of bacteria, fungi or plant and insect cells under different cultivation parameters • Automated cell disruption and extraction systems for the downstream analysis of DNA, RNA, proteins, lipids, and primary and secondary metabolites • Genomics services: cooperation with state-of-the-art next-generation sequencing (NGS) facilities and MySeq benchtop sequencer for flexible genotyping in small-medium scale projects. Additionally, on-site infrastructure for bioinformatics data analysis and scientific project management • Metabolomics: IFA Center for Analytical Services: Infrastructure (Mass spectrometry) suitable for metabolomics of primary and secondary metabolism • Proteomics: protein / peptide mass spectrometry; VetMed "VetCore" Infrastructure with focus on "Post-translational modification" (PTM) proteomics • Personnel: BiMM is fully operated in each of the four Units by own Staff Scientists and Technicians For further questions or discussions on terms of usage, project details and time tables, please contact scot@wallace.at with essential input.
bioactive substances antibiotics plant protection enzymes null
Publikationen
Project staff
Joseph Strauss
Univ.Prof. Mag.rer.nat. Dr.rer.nat. Joseph Strauss
joseph.strauss@boku.ac.at
Tel: +43 1 47654-94420
Project Leader
01.10.2014 - 31.12.2020
Michael Sulyok
Dipl.-Ing. Dr.techn. Michael Sulyok
michael.sulyok@boku.ac.at
Tel: +43 1 47654-97312
Project Staff
01.10.2014 - 31.12.2020
BOKU partners
External partners
University of Veterinary Medicine Vienna
none
partner