Detection, identification, molecular structure and quantification of bioactive compounds
Abstract
Fusarium fungi can infect cereals and can produce a whole array of mycotoxins in cereal kernels. The most important mycotoxins are the so-called trichothecenes. They are toxic for human beings and animals. In this project we want to minimize Fusarium infections on the cereal ears in the field. This reduces the risk of mycotoxin contamination and prevents the entrance of these substances in the food and feed chain. We aim to isolate, to purify, to characterize and to apply microorganisms and bioactive compounds that either 1) block germination and growth of Fusarium spores, 2) inhibit the production of trichothecenes or 3) trigger natural plant defence against Fusarium. At the Center for Analytical Chemistry, responsible for the subproject “Detection, structure elucidation and quantification of bioactive compounds” complex organic extracts are fractionated. To test and apply new interesting bioactive compounds it is necessary to isolate them and to elucidate their chemical structure. To this end, a preparative isolation and purification of these substances is performed. For the identification and characterization of the chemical structure, state-of-the-art mass-spectrometric techniques are used.
Publikationen
Project staff
Rainer Schuhmacher
Univ.Prof. Dipl.-Chem. Dr.rer.nat. Rainer Schuhmacher
rainer.schuhmacher@boku.ac.at
Tel: +43 1 47654-97307
BOKU Project Leader
01.01.2008 - 31.12.2013