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Metabolomics of Trichoderma: Studying the molecular mechanisms of biocontrol

Project Leader
Schuhmacher Rainer, BOKU Project Leader
Type of Research
Basic Research
Project partners
Bhabha Atomic Research Centre, Mumbai, India.
Contact person: Dr. Prasun K Mukherjee;
Function of the Project Partner: Partner
Hebrew University of Jerusalem, Jerusalem, Israel.
Contact person: Dr. Ada Viterbo;
Function of the Project Partner: Partner
Texas A&M University, College Station, United States (USA).
Contact person: Dr. Charles M. Kenerley;
Function of the Project Partner: Partner
Vienna University of Technology, Division of process engineering, Getreidemarkt 9/166-2, 1060 Wien, Austria.
Contact person: Dr. Susanne Zeilinger;
Function of the Project Partner: Partner
Vienna Technical University, Institute of Applied Synthetic Chemistry , Getreidemarkt 9/163 , 1060 Wien, Austria.
Contact person: Dr. Christian Hametner;
Function of the Project Partner: Partner
BOKU Research Units
Institute for Biotechnology in Plant Production
Institute of Bioanalytics and Agro-Metabolomics
Funded by
Department for Agrobiotechnology, IFA-Tulln, Konrad-Lorenz-Stra├če 20, 3430 Tulln, Austria
Trichoderma spp. are filamentous fungi which frequently colonise soil and plant roots. They are potent parasites of phytopathogenic fungi (mycoparasites) and some Trichoderma species are also able to induce systemic resistance in plants. Therefore, these fungi are commercially used as biological control agents as an alternative to synthetic pesticides.
The aim of this project is to develop and apply analytical methods for the study of the molecular mechanisms underlying the interactions of Trichoderma with both plants and phytopathogenic fungi.
So far we have developed GC-MS and LC-MS(/MS) based methods for the profiling of bioactive secondary metabolites such as peptaibiotics, siderophores and volatiles. In close cooperation with molecular biologists, mycologists and plant pathologists, we currently apply these methods to investigate the metabolome of Trichoderma as well as the molecular crosstalk of the fungus with its living environment.
We expect that the results of the project will provide a better understanding of the complex mechanisms involved in mycoparasitism and biocontrol.
analytical chemistry; biological engineering; genetic engineering; plant protection;
analytical chemistry; biotechnology; mass spectrometry; Metabolomics; Trichoderma;
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