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Suchbegriffe: Pichia pastoris, . Treffer: 68

** = Publikationen gelistet in SCI/SSCI (veröffentlicht im Web of Science)
* = Publikationen in sonstigen peer-reviewten Journalen (ggf. noch nicht im WoS veröffentlicht)
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** Heistinger, L; Dohm, JC; Paes, BG; Koizar, D; Troyer, C; Ata, O; Steininger-Mairinger, T; Mattanovich, D Genotypic and phenotypic diversity among Komagataella species reveals a hidden pathway for xylose utilization.

MICROB CELL FACT. 2022; 21(1), 70 WoS PubMed FullText FullText_BOKU

** Tir, N; Heistinger, L; Grunwald-Gruber, C; Jakob, LA; Dickgiesser, S; Rasche, N; Mattanovich, D From strain engineering to process development: monoclonal antibody production with an unnatural amino acid in Pichia pastoris.

MICROB CELL FACT. 2022; 21(1), 157 WoS PubMed FullText FullText_BOKU

** Wasito, H; Hermann, G; Fitz, V; Troyer, C; Hann, S; Koellensperger, G Yeast-based reference materials for quantitative metabolomics.

ANAL BIOANAL CHEM. 2022; 414(15): 4359-4368. WoS PubMed FullText FullText_BOKU


** Barbay, D; Macakova, M; Sutzl, L; De, S; Mattanovich, D; Gasser, B Two homologs of the Cat8 transcription factor are involved in the regulation of ethanol utilization in Komagataella phaffii.

CURR GENET. 2021; 67(4): 641-661. WoS PubMed FullText FullText_BOKU

** Staudacher, J; Rebnegger, C; Gasser, B Treatment with surfactants enables quantification of translational activity by O-propargyl-puromycin labelling in yeast.

BMC MICROBIOL. 2021; 21(1), 120 WoS PubMed FullText FullText_BOKU

** Totaro, D; Radoman, B; Schmelzer, B; Rothbauer, M; Steiger, MG; Mayr, T; Sauer, M; Ertl, P; Mattanovich, D; Microscale Perfusion-Based Cultivation for Pichia pastoris Clone Screening Enables Accelerated and Optimized Recombinant Protein Production Processes..

Biotechnol J. 2021; 16(3):e2000215 WoS PubMed FullText FullText_BOKU

** Wohlschlager, L; Csarman, F; Zrilic, M; Seiboth, B; Ludwig, R Comparative characterization of glyoxal oxidase from Phanerochaete chrysosporium expressed at high levels in Pichia pastoris and Trichoderma reesei.

ENZYME MICROB TECH. 2021; 145, 109748 WoS PubMed FullText FullText_BOKU


** De, S; Rebnegger, C; Moser, J; Tatto, N; Graf, AB; Mattanovich, D; Gasser, B Pseudohyphal differentiation in Komagataella phaffii: investigating the FLO gene family.

FEMS YEAST RES. 2020; 20(5), foaa044 WoS PubMed FullText FullText_BOKU

** Ergün, BG; Demir, İ; Özdamar, TH; Gasser, B; Mattanovich, D; Çalık, P; Engineered Deregulation of Expression in Yeast with Designed Hybrid-Promoter Architectures in Coordination with Discovered Master Regulator Transcription Factor..

Adv Biosyst. 2020; 4(4):e1900172 WoS PubMed FullText FullText_BOKU

** Valli, M; Grillitsch, K; Grünwald-Gruber, C; Tatto, NE; Hrobath, B; Klug, L; Ivashov, V; Hauzmayer, S; Koller, M; Tir, N; Leisch, F; Gasser, B; Graf, AB; Altmann, F; Daum, G; Mattanovich, D; A subcellular proteome atlas of the yeast Komagataella phaffii..

FEMS Yeast Res. 2020; 20(1): WoS PubMed PUBMED Central FullText FullText_BOKU


** Ergün, BG; Gasser, B; Mattanovich, D; Çalık, P; Engineering of alcohol dehydrogenase 2 hybrid-promoter architectures in Pichia pastoris to enhance recombinant protein expression on ethanol..

Biotechnol Bioeng. 2019; 116(10):2674-2686 WoS PubMed FullText FullText_BOKU


** Gasser, B; Mattanovich, D A yeast for all seasons - Is Pichia pastoris a suitable chassis organism for future bioproduction?.

FEMS MICROBIOL LETT. 2018; 365(17): WoS PubMed FullText FullText_BOKU

** Heistinger, L; Gasser, B; Mattanovich, D Creation of Stable Heterothallic Strains of Komagataella phaffii Enables Dissection of Mating Gene Regulation.

MOL CELL BIOL. 2018; 38(2): WoS PubMed FullText FullText_BOKU

** Heistinger, L; Moser, J; Tatto, NE; Valli, M; Gasser, B; Mattanovich, D Identification and characterization of the Komagataella phaffii mating pheromone genes.

FEMS YEAST RES. 2018; 18(5): WoS PubMed FullText FullText_BOKU

** Pekarsky, A; Veiter, L; Rajamanickam, V; Herwig, C; Grunwald-Gruber, C; Altmann, F; Spadiut, O Production of a recombinant peroxidase in different glyco-engineered Pichia pastoris strains: a morphological and physiological comparison.

MICROB CELL FACT. 2018; 17: WoS PubMed FullText FullText_BOKU

** Peña, DA; Gasser, B; Zanghellini, J; Steiger, MG; Mattanovich, D; Metabolic engineering of Pichia pastoris..

Metab Eng. 2018; 50:2-15 WoS PubMed FullText FullText_BOKU

** Prielhofer, R; Reichinger, M; Wagner, N; Claes, K; Kiziak, C; Gasser, B; Mattanovich, D Superior protein titers in half the fermentation time: Promoter and process engineering for the glucose-regulated GTH1 promoter of Pichia pastoris.

BIOTECHNOL BIOENG. 2018; 115(10): 2479-2488. WoS PubMed FullText FullText_BOKU


** Ata, O; Prielhofer, R; Gasser, B; Mattanovich, D; Calik, P Transcriptional engineering of the glyceraldehyde-3-phosphate dehydrogenase promoter for improved heterologous protein production in Pichia pastoris.

BIOTECHNOL BIOENG. 2017; 114(10): 2319-2327. WoS PubMed FullText FullText_BOKU

** Burgard, J; Valli, M; Graf, AB; Gasser, B; Mattanovich, D Biomarkers allow detection of nutrient limitations and respective supplementation for elimination in Pichia pastoris fed-batch cultures.

MICROB CELL FACT. 2017; 16: WoS PubMed PUBMED Central FullText FullText_BOKU

** Gamerith, C; Vastano, M; Ghorbanpour, SM; Zitzenbacher, S; Ribitsch, D; Zumstein, MT; Sander, M; Acero, EH; Pellis, A; Guebitz, GM Enzymatic Degradation of Aromatic and Aliphatic Polyesters by P. pastoris Expressed Cutinase 1 from Thermobifida cellulosilytica.

FRONT MICROBIOL. 2017; 8: WoS PubMed FullText FullText_BOKU

** Ma, S; Preims, M; Piumi, F; Kappel, L; Seiboth, B; Record, E; Kracher, D; Ludwig, R; Molecular and catalytic properties of fungal extracellular cellobiose dehydrogenase produced in prokaryotic and eukaryotic expression systems..

Microb Cell Fact. 2017; 16(1):37 WoS PubMed PUBMED Central FullText FullText_BOKU

** Mattanovich, M; Russmayer, H; Scharl-Hirsch, T; Puxbaum, V; Burgard, J; Mattanovich, D; Hann, S Metabolomics of Pichia pastoris: impact of buffering conditions on the kinetics and nature of metabolite loss during quenching.

FEMS YEAST RES. 2017; 17(3): WoS PubMed FullText FullText_BOKU

** Moser, JW; Prielhofer, R; Gerner, SM; Graf, AB; Wilson, IB; Mattanovich, D; Dragosits, M; Implications of evolutionary engineering for growth and recombinant protein production in methanol-based growth media in the yeast Pichia pastoris..

Microb Cell Fact. 2017; 16(1):49 WoS PubMed FullText FullText_BOKU

** Moser, JW; Wilson, IBH; Dragosits, M The adaptive landscape of wildtype and glycosylation-deficient populations of the industrial yeast Pichia pastoris.

BMC GENOMICS. 2017; 18: WoS PubMed FullText FullText_BOKU

** Prielhofer, R; Barrero, JJ; Steuer, S; Gassler, T; Zahrl, R; Baumann, K; Sauer, M; Mattanovich, D; Gasser, B; Marx, H GoldenPiCS: a Golden Gate-derived modular cloning system for applied synthetic biology in the yeast Pichia pastoris.

BMC SYST BIOL. 2017; 11: WoS PubMed FullText FullText_BOKU

** Si-Hung, L; Causon, TJ; Hann, S Comparison of fully wettable RPLC stationary phases for LC-MS-based cellular metabolomics.

ELECTROPHORESIS. 2017; 38(18): 2287-2295. WoS PubMed FullText FullText_BOKU


** Landes, N; Gasser, B; Vorauer-Uhl, K; Lhota, G; Mattanovich, D; Maurer, M; The vitamin-sensitive promoter PTHI11 enables pre-defined autonomous induction of recombinant protein production in Pichia pastoris..

Biotechnol Bioeng. 2016; 113(12):2633-2643 WoS PubMed FullText FullText_BOKU

** Puxbaum, V; Gasser, B; Mattanovich, D; The bud tip is the cellular hot spot of protein secretion in yeasts..

Appl Microbiol Biotechnol. 2016; 100(18):8159-8168 WoS PubMed FullText FullText_BOKU

** Rueda, F; Gasser, B; Sanchez-Chardi, A; Roldan, M; Villegas, S; Puxbaum, V; Ferrer-Miralles, N; Unzueta, U; Vazquez, E; Garcia-Fruitos, E; Mattanovich, D; Villaverde, A Functional inclusion bodies produced in the yeast Pichia pastoris.

MICROB CELL FACT. 2016; 15: WoS PubMed PUBMED Central FullText FullText_BOKU


** Gasser, B; Steiger, MG; Mattanovich, D; Methanol regulated yeast promoters: production vehicles and toolbox for synthetic biology..

Microb Cell Fact. 2015; 14:196 WoS PubMed PUBMED Central FullText FullText_BOKU

** Gmeiner, C; Saadati, A; Maresch, D; Krasteva, S; Frank, M; Altmann, F; Herwig, C; Spadiut, O Development of a fed-batch process for a recombinant Pichia pastoris Delta och1 strain expressing a plant peroxidase.

MICROB CELL FACT. 2015; 14: WoS PubMed PUBMED Central FullText FullText_BOKU

** Molina-Espeja, P; Ma, S; Mate, DM; Ludwig, R; Alcalde, M; Tandem-yeast expression system for engineering and producing unspecific peroxygenase..

Enzyme Microb Technol. 2015; 73-74:29-33 WoS PubMed FullText FullText_BOKU

** Prielhofer, R; Cartwright, SP; Graf, AB; Valli, M; Bill, RM; Mattanovich, D; Gasser, B; Pichia pastoris regulates its gene-specific response to different carbon sources at the transcriptional, rather than the translational, level..

BMC Genomics. 2015; 16:167 WoS PubMed PUBMED Central FullText FullText_BOKU

** Puxbaum, V; Mattanovich, D; Gasser, B Quo vadis? The challenges of recombinant protein folding and secretion in Pichia pastoris.

APPL MICROBIOL BIOT. 2015; 99(7): 2925-2938. WoS PubMed FullText FullText_BOKU

** Rußmayer, H; Buchetics, M; Gruber, C; Valli, M; Grillitsch, K; Modarres, G; Guerrasio, R; Klavins, K; Neubauer, S; Drexler, H; Steiger, M; Troyer, C; Al Chalabi, A; Krebiehl, G; Sonntag, D; Zellnig, G; Daum, G; Graf, AB; Altmann, F; Koellensperger, G; Hann, S; Sauer, M; Mattanovich, D; Gasser, B; Systems-level organization of yeast methylotrophic lifestyle..

BMC Biol. 2015; 13:80 WoS PubMed PUBMED Central FullText FullText_BOKU

** Russmayer, H; Troyer, C; Neubauer, S; Steiger, MG; Gasser, B; Hann, S; Koellensperger, G; Sauer, M; Mattanovich, D; Metabolomics sampling of Pichia pastoris revisited: rapid filtration prevents metabolite loss during quenching..

FEMS Yeast Res. 2015; 15(6): WoS PubMed FullText FullText_BOKU


** Capone, S; Pletzenauer, R; Maresch, D; Metzger, K; Altmann, F; Herwig, C; Spadiut, O Glyco-variant library of the versatile enzyme horseradish peroxidase.

GLYCOBIOLOGY. 2014; 24(9): 852-863. WoS PubMed PUBMED Central FullText FullText_BOKU

** Dragosits, M; Pflügl, S; Kurz, S; Razzazi-Fazeli, E; Wilson, IB; Rendic, D Recombinant Aspergillus â-galactosidases as a robust glycomic and biotechnological tool..

Appl Microbiol Biotechnol. 2014; 98(8):3553-3567 WoS PubMed PUBMED Central FullText FullText_BOKU

** Klug, L; Tarazona, P; Gruber, C; Grillitsch, K; Gasser, B; Trotzmuller, M; Kofeler, H; Leitner, E; Feussner, I; Mattanovich, D; Altmann, F; Daum, G The lipidome and proteome of microsomes from the methylotrophic yeast Pichia pastoris.

BBA-MOL CELL BIOL L. 2014; 1841(2): 215-226. WoS PubMed FullText FullText_BOKU

** Ruth, C; Buchetics, M; Vidimce, V; Kotz, D; Naschberger, S; Mattanovich, D; Pichler, H; Gasser, B Pichia pastoris Aft1-a novel transcription factor, enhancing recombinant protein secretion.

MICROB CELL FACT. 2014; 13: WoS PubMed PUBMED Central FullText FullText_BOKU


** Delic, M; Mattanovich, D; Gasser, B Repressible promoters - A novel tool to generate conditional mutants in Pichia pastoris.

MICROB CELL FACT. 2013; 12: WoS PubMed PUBMED Central FullText FullText_BOKU

** Heiss, S; Maurer, M; Hahn, R; Mattanovich, D; Gasser, B; Identification and deletion of the major secreted protein of Pichia pastoris..

Appl Microbiol Biotechnol. 2013; 97(3):1241-1249 WoS PubMed FullText FullText_BOKU

** Klavins, K; Neubauer, S; Al Chalabi, A; Sonntag, D; Haberhauer-Troyer, C; Russmayer, H; Sauer, M; Mattanovich, D; Hann, S; Koellensperger, G Interlaboratory comparison for quantitative primary metabolite profiling in Pichia pastoris..

Anal Bioanal Chem. 2013; 405(15):5159-5169 WoS PubMed FullText FullText_BOKU

** Mate, DM; Gonzalez-Perez, D; Kittl, R; Ludwig, R; Alcalde, M Functional expression of a blood tolerant laccase in Pichia pastoris.

BMC BIOTECHNOL. 2013; 13: WoS FullText FullText_BOKU

** Prielhofer, R; Maurer, M; Klein, J; Wenger, J; Kiziak, C; Gasser, B; Mattanovich, D Induction without methanol: novel regulated promoters enable high-level expression in Pichia pastoris.

MICROB CELL FACT. 2013; 12: WoS FullText FullText_BOKU


** Harreither, W; Felice, AKG; Paukner, R; Gorton, L; Ludwig, R; Sygmund, C Recombinantly produced cellobiose dehydrogenase from Corynascus thermophilus for glucose biosensors and biofuel cells.

BIOTECHNOL J. 2012; 7(11): WoS PubMed FullText FullText_BOKU

** Kittl, R; Mueangtoom, K; Gonaus, C; Khazaneh, ST; Sygmund, C; Haltrich, D; Ludwig, R A chloride tolerant laccase from the plant pathogen ascomycete Botrytis aclada expressed at high levels in Pichia pastoris..

J Biotechnol. 2012; 157(2):304-314 WoS PubMed FullText FullText_BOKU

** Neubauer, S; Haberhauer-Troyer, C; Klavins, K; Russmayer, H; Steiger, MG; Gasser, B; Sauer, M; Mattanovich, D; Hann, S; Koellensperger, G; U13C cell extract of Pichia pastoris--a powerful tool for evaluation of sample preparation in metabolomics..

J Sep Sci. 2012; 35(22):3091-3105 WoS PubMed FullText FullText_BOKU

** Pfeffer, M; Maurer, M; Stadlmann, J; Grass, J; Delic, M; Altmann, F; Mattanovich, D; Intracellular interactome of secreted antibody Fab fragment in Pichia pastoris reveals its routes of secretion and degradation..

Appl Microbiol Biotechnol. 2012; 93(6):2503-2512 WoS PubMed FullText FullText_BOKU

** Sygmund, C; Gutmann, A; Krondorfer, I; Kujawa, M; Glieder, A; Pscheidt, B; Haltrich, D; Peterbauer, C; Kittl, R; Simple and efficient expression of Agaricus meleagris pyranose dehydrogenase in Pichia pastoris..

Appl Microbiol Biotechnol. 2012; 94(3):695-704 WoS PubMed PUBMED Central FullText FullText_BOKU


** Buchetics, M; Dragosits, M; Maurer, M; Rebnegger, C; Porro, D; Sauer, M; Gasser, B; Mattanovich, D Reverse Engineering of Protein Secretion by Uncoupling of Cell Cycle Phases From Growth.

BIOTECHNOL BIOENG. 2011; 108(10): 2403-2412. WoS FullText FullText_BOKU

** Dragosits, M; Frascotti, G; Bernard-Granger, L; Vazquez, F; Giuliani, M; Baumann, K; Rodriguez-Carmona, E; Tokkanen, J; Parrilli, E; Wiebe, MG; Kunert, R; Maurer, M; Gasser, B; Sauer, M; Branduardi, P; Pakula, T; Saloheimo, M; Penttila, M; Ferrer, P; Tutino, ML; Villaverde, A; Porro, D; Mattanovich, D Influence of Growth Temperature on the Production of Antibody Fab Fragments in Different Microbes: A Host Comparative Analysis.

BIOTECHNOL PROGR. 2011; 27(1): 38-46. WoS PubMed FullText FullText_BOKU


** Delic, M; Mattanovich, D; Gasser, B; Monitoring intracellular redox conditions in the endoplasmic reticulum of living yeasts..

FEMS Microbiol Lett. 2010; 306(1):61-66 WoS PubMed FullText FullText_BOKU

** Sohn, SB; Graf, AB; Kim, TY; Gasser, B; Maurer, M; Ferrer, P; Mattanovich, D; Lee, SY Genome-scale metabolic model of methylotrophic yeast Pichia pastoris and its use for in silico analysis of heterologous protein production.

BIOTECHNOL J. 2010; 5(7): 705-715. WoS PubMed FullText FullText_BOKU

** Stadlmayr, G; Benakovitsch, K; Gasser, B; Mattanovich, D; Sauer, M; Genome-scale analysis of library sorting (GALibSo): Isolation of secretion enhancing factors for recombinant protein production in Pichia pastoris..

Biotechnol Bioeng. 2010; 105(3):543-555 WoS PubMed FullText FullText_BOKU

** Stadlmayr, G; Mecklenbräuker, A; Rothmüller, M; Maurer, M; Sauer, M; Mattanovich, D; Gasser, B; Identification and characterisation of novel Pichia pastoris promoters for heterologous protein production..

J Biotechnol. 2010; 150(4):519-529 WoS PubMed FullText FullText_BOKU


** Dragosits M, Stadlmann J, Albiol J, Baumann K, Maurer M, Gasser B, Sauer M, Altmann F, Ferrer P, Mattanovich D. The effect of temperature on the proteome of recombinant Pichia pastoris..

J PROTEOME RES, 8(3), 1380-1392; ISSN 1535-3893 WoS FullText FullText_BOKU

** Graf, A; Dragosits, M; Gasser, B; Mattanovich, D Yeast systems biotechnology for the production of heterologous proteins.

FEMS YEAST RES. 2009; 9(3): 335-348. WoS PubMed FullText FullText_BOKU

** Marx, H; Mecklenbräuker, A; Gasser, B; Sauer, M; Mattanovich, D; Directed gene copy number amplification in Pichia pastoris by vector integration into the ribosomal DNA locus..

FEMS Yeast Res. 2009; 9(8):1260-1270 WoS PubMed FullText FullText_BOKU

** Resina, D; Maurer, M; Cos, O; Arnau, C; Carnicer, M; Marx, H; Gasser, B; Valero, F; Mattanovich, D; Ferrer, P Engineering of bottlenecks in Rhizopus oryzae lipase production in Pichia pastoris using the nitrogen source-regulated FLD1 promoter.

NEW BIOTECHNOL. 2009; 25(6): 396-403. WoS PubMed FullText FullText_BOKU


** Baumann, K; Maurer, M; Dragosits, M; Cos, O; Ferrer, P; Mattanovich, D Hypoxic fed-batch cultivation of Pichia pastoris increases specific and volumetric productivity of recombinant proteins..

Biotechnol Bioeng. 2008; 100(1):177-183 WoS PubMed FullText FullText_BOKU

** Zamocky, M; Schumann, C; Sygmund, C; O'Callaghan, J; Dobson, ADW; Ludwig, R; Haltrich, D; Peterbauer, CK Cloning, sequence analysis and heterologous expression in Pichia pastoris of a gene encoding a thermostable cellobiose dehydrogenase from Myriococcum thermophilum.

PROTEIN EXPRESS PURIF. 2008; 59(2): 258-265. WoS FullText FullText_BOKU


** Gach, JS; Maurer, M; Hahn, R; Gasser, B; Mattanovich, D; Katinger, H; Kunert, R High level expression of a promising anti-idiotypic antibody fragment vaccine against HIV-1 in Pichia pastoris..

J Biotechnol. 2007; 128(4):735-746 WoS PubMed FullText FullText_BOKU

** Wriessnegger, T; Gubitz, G; Leitner, E; Ingolic, E; Cregg, J; de la Cruz, BJ; Daum, G Lipid composition of peroxisomes from the yeast Pichia pastoris grown on different carbon sources.

BBA-MOL CELL BIOL L. 2007; 1771(4): 455-461. WoS FullText FullText_BOKU


** Gasser, B; Maurer, M; Gach, J; Kunert, R; Mattanovich, D; Engineering of Pichia pastoris for improved production of antibody fragments..

Biotechnol Bioeng. 2006; 94(2):353-361 WoS PubMed FullText FullText_BOKU

** Marx, H; Sauer, M; Resina, D; Vai, M; Porro, D; Valero, F; Ferrer, P; Mattanovich, D Cloning, disruption and protein secretory phenotype of the GAS1 homologue of Pichia pastoris..

FEMS Microbiol Lett. 2006; 264(1):40-47 WoS PubMed FullText FullText_BOKU


** Hohenblum, H; Gasser, B; Maurer, M; Borth, N; Mattanovich, D; Effects of gene dosage, promoters, and substrates on unfolded protein stress of recombinant Pichia pastoris..

Biotechnol Bioeng. 2004; 85(4):367-375 WoS PubMed FullText FullText_BOKU


** Hohenblum, H; Borth, N; Mattanovich, D Assessing viability and cell-associated product of recombinant protein producing Pichia pastoris with flow cytometry..

J Biotechnol. 2003; 102(3):281-290 WoS PubMed FullText FullText_BOKU

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