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Search Items: CHO cells, . hits: 20

** = Publications listed in SCI/SSCI - Journals (published in Web of Science)
* = peer-reviewed publication (not listed in SCI/SSCI)
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** Borsi, G; Motheramgari, K; Dhiman, H; Baumann, M; Sinkala, E; Sauerland, M; Riba, J; Borth, N; Single-cell RNA sequencing reveals homogeneous transcriptome patterns and low variance in a suspension CHO-K1 and an adherent HEK293FT cell line in culture conditions..

J Biotechnol. 2023; 364:13-22 WoS PubMed FullText FullText_BOKU

** Novak, N; Baumann, M; Friss, A; Cairns, V; DeMaria, C; Borth, N LncRNA analysis of mAb producing CHO clones reveals marker and engineering potential.

METAB ENG. 2023; 78: 26-40. WoS PubMed FullText FullText_BOKU


** Weinguny, M; Eisenhut, P; Klanert, G; Virgolini, N; Marx, N; Jonsson, A; Ivansson, D; Lovgren, A; Borth, N Random epigenetic modulation of CHO cells by repeated knockdown of DNA methyltransferases increases population diversity and enables sorting of cells with higher production capacities.

BIOTECHNOL BIOENG. 2020; 117(11): 3435-3447. WoS PubMed FullText FullText_BOKU

** Weinguny, M; Klanert, G; Eisenhut, P; Jonsson, A; Ivansson, D; Lovgren, A; Borth, N Directed evolution approach to enhance efficiency and speed of outgrowth during single cell subcloning of Chinese Hamster Ovary cells.

COMPUT STRUCT BIOTEC. 2020; 18: 1320-1329. WoS PubMed FullText FullText_BOKU


** Bydlinski, N; Maresch, D; Schmieder, V; Klanert, G; Strasser, R; Borth, N The contributions of individual galactosyltransferases to protein specific N-glycan processing in Chinese Hamster Ovary cells.

J BIOTECHNOL. 2018; 282: 101-110. WoS PubMed FullText FullText_BOKU

** Pristovsek, N; Hansen, HG; Sergeeva, D; Borth, N; Lee, GM; Andersen, MR; Kildegaard, HF Using Titer and Titer Normalized to Confluence Are Complementary Strategies for Obtaining Chinese Hamster Ovary Cell Lines with High Volumetric Productivity of Etanercept.

BIOTECHNOL J. 2018; 13(3): WoS PubMed FullText FullText_BOKU

** Vcelar, S; Melcher, M; Auer, N; Hrdina, A; Puklowski, A; Leisch, F; Jadhav, V; Wenger, T; Baumann, M; Borth, N Changes in Chromosome Counts and Patterns in CHO Cell Lines upon Generation of Recombinant Cell Lines and Subcloning.

BIOTECHNOL J. 2018; 13(3): WoS PubMed FullText FullText_BOKU


** Galleguillos, SN; Ruckerbauer, D; Gerstl, MP; Borth, N; Hanscho, M; Zanghellini, J; What can mathematical modelling say about CHO metabolism and protein glycosylation?.

Comput Struct Biotechnol J. 2017; 15:212-221 WoS PubMed PUBMED Central FullText FullText_BOKU


** Bort, JAH; Shanmukam, V; Pabst, M; Windwarder, M; Neumann, L; Alchalabi, A; Krebiehl, G; Koellensperger, G; Hann, S; Sonntag, D; Altmann, F; Heel, C; Borth, N Reduced quenching and extraction time for mammalian cells using filtration and syringe extraction.

J BIOTECHNOL. 2014; 182: 97-103. WoS PubMed PUBMED Central FullText FullText_BOKU

** Maccani, A; Landes, N; Stadlmayr, G; Maresch, D; Leitner, C; Maurer, M; Gasser, B; Ernst, W; Kunert, R; Mattanovich, D Pichia pastoris secretes recombinant proteins less efficiently than Chinese hamster ovary cells but allows higher space-time yields for less complex proteins.

BIOTECHNOL J. 2014; 9(4): 526-537. WoS PubMed PUBMED Central FullText FullText_BOKU


** Hernández Bort, JA; Hackl, M; Höflmayer, H; Jadhav, V; Harreither, E; Kumar, N; Ernst, W; Grillari, J; Borth, N; Dynamic mRNA and miRNA profiling of CHO-K1 suspension cell cultures..

Biotechnol J. 2012; 7(4):500-515 WoS PubMed FullText FullText_BOKU


** Glassey, J; Gernaey, KV; Clemens, C; Schulz, TW; Oliveira, R; Striedner, G; Mandenius, CF Process analytical technology (PAT) for biopharmaceuticals.

BIOTECHNOL J. 2011; 6(4): 369-377. WoS PubMed FullText FullText_BOKU

** Pichler, J; Galosy, S; Mott, J; Borth, N Selection of CHO Host Cell Subclones With Increased Specific Antibody Production Rates by Repeated Cycles of Transient Transfection and Cell Sorting.

BIOTECHNOL BIOENG. 2011; 108(2): 386-394. WoS PubMed FullText FullText_BOKU


** Damiani, R; Oliveira, JE; Vorauer-Uhl, K; Peroni, CN; Vianna, EG; Bartolini, P; Ribela, MTCP Stable expression of a human-like sialylated recombinant thyrotropin in a Chinese hamster ovary cell line expressing alpha 2,6-sialyltransferase.

PROTEIN EXPRESS PURIF. 2009; 67(1): 7-14. WoS FullText FullText_BOKU

** Pichler, J; Hesse, F; Wieser, M; Kunert, R; Galosy, SS; Mott, JE; Borth, N A study on the temperature dependency and time course of the cold capture antibody secretion assay..

J Biotechnol. 2009; 141(1-2):80-83 WoS PubMed FullText FullText_BOKU


** Reisinger, H; Steinfellner, W; Stern, B; Katinger, H; Kunert, R The absence of effect of gene copy number and mRNA level on the amount of mAb secretion from mammalian cells..

Appl Microbiol Biotechnol. 2008; 81(4):701-710 WoS PubMed FullText FullText_BOKU


** Schriebl, K; Trummer, E; Lattenmayer, C; Weik, R; Kunert, R; Müller, D; Katinger, H; Vorauer-Uhl, K Biochemical characterization of rhEpo-Fc fusion protein expressed in CHO cells..

Protein Expr Purif. 2006; 49(2):265-275 WoS PubMed FullText FullText_BOKU

** Schriebl, K; Trummer, E; Weik, R; Müller, D; Kunert, R; Lattenmayer, C; Katinger, H; Vorauer-Uhl, K A novel strategy for quantitative isoform detection directly performed from culture supernatant..

J Pharm Biomed Anal. 2006; 42(3):322-327 WoS PubMed FullText FullText_BOKU

** Trummer, E; Fauland, K; Seidinger, S; Schriebl, K; Lattenmayer, C; Kunert, R; Vorauer-Uhl, K; Weik, R; Borth, N; Katinger, H; Müller, D Process parameter shifting: Part I. Effect of DOT, pH, and temperature on the performance of Epo-Fc expressing CHO cells cultivated in controlled batch bioreactors..

Biotechnol Bioeng. 2006; 94(6):1033-1044 WoS PubMed FullText FullText_BOKU

** Trummer, E; Fauland, K; Seidinger, S; Schriebl, K; Lattenmayer, C; Kunert, R; Vorauer-Uhl, K; Weik, R; Borth, N; Katinger, H; Müller, D Process parameter shifting: Part II. Biphasic cultivation-A tool for enhancing the volumetric productivity of batch processes using Epo-Fc expressing CHO cells..

Biotechnol Bioeng. 2006; 94(6):1045-1052 WoS PubMed FullText FullText_BOKU

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