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Gewählte Publikation:

Michel, S; Wagner, C; Nosenko, T; Steiner, B; Samad-Zamini, M; Buerstmayr, M; Mayer, K; Buerstmayr, H.
(2021): Merging Genomics and Transcriptomics for Predicting Fusarium Head Blight Resistance in Wheat
GENES-BASEL. 2021; 12(1), 114 FullText FullText_BOKU

Genomic selection with genome-wide distributed molecular markers has evolved into a well-implemented tool in many breeding programs during the last decade. The resistance against Fusarium head blight (FHB) in wheat is probably one of the most thoroughly studied systems within this framework. Aside from the genome, other biological strata like the transcriptome have likewise shown some potential in predictive breeding strategies but have not yet been investigated for the FHB-wheat pathosystem. The aims of this study were thus to compare the potential of genomic with transcriptomic prediction, and to assess the merit of blending incomplete transcriptomic with complete genomic data by the single-step method. A substantial advantage of gene expression data over molecular markers has been observed for the prediction of FHB resistance in the studied diversity panel of breeding lines and released cultivars. An increase in prediction ability was likewise found for the single-step predictions, although this can mostly be attributed to an increased accuracy among the RNA-sequenced genotypes. The usage of transcriptomics can thus be seen as a complement to already established predictive breeding pipelines with pedigree and genomic data, particularly when more cost-efficient multiplexing techniques for RNA-sequencing will become more accessible in the future.
Autor*innen der BOKU Wien:
Bürstmayr Hermann
Bürstmayr Maria
Michel Sebastian
Samad Zamini Mina
Steiner Barbara
Wagner Christian

Find related publications in this database (Keywords)
Fusarium head blight
genomic prediction
omics-based prediction

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