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Gewählte Publikation:

Bertheau, C; Schuler, H; Krumböck, S; Arthofer, W; Stauffer, C; .
(2011): Hit or miss in phylogeographic analyses: the case of the cryptic NUMTs.
Mol Ecol Resour. 2011; 11(6):1056-1059 FullText FullText_BOKU

Phylogeographic studies call for attention as nuclear copies of mitochondrial DNA (NUMT) may generate erroneous results. Here, we report the presence of NUMTs differing only by 1-3 bp from authentic mitochondrial haplotypes, consequently named cryptic NUMTs. In contrast to traditional NUMTs, for which reliable tools for detection are established, cryptic NUMTs question the validity of phylogeographic analyses based solely on mitochondrial DNA, like the one presented here on the European bark beetle Ips typographus. Caution is called as cryptic NUMTs might be responsible for haplotype richness found in several species, and the necessity of refined methods for NUMT detection is highlighted.
Autor*innen der BOKU Wien:
Bertheau Coralie
Schuler Hannes
Stauffer Christian
Find related publications in this database (using NML MeSH Indexing)
Animals;Base Sequence;Beetles/genetics*;Cell Nucleus/genetics*;DNA, Mitochondrial/genetics*;Electron Transport Complex IV/genetics;Europe;Haplotypes/genetics;Molecular Sequence Data;Phylogeography/methods*;Research Design;Sequence Analysis, DNA;

Find related publications in this database (Keywords)
Ips typographus
mitochondrial DNA

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