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Gewählte Publikation:

Konst, P; Kara, S; Kochius, S; Holtmann, D; Arends, IWCE; Ludwig, R; Hollmann, F.
(2013): Expanding the Scope of Laccase-Mediator Systems
CHEMCATCHEM. 2013; 5(10): 3027-3032. FullText FullText_BOKU

Abstract:
The laccase-mediator system (LMS) for the regeneration of oxidised nicotinamide co-factors was revisited to broaden the mediator scope. Among the 18 mediators screened, acetosyringone, syringaldehyde and caffeic acid excelled with respect to activity and stability under process conditions. The LMS based on the laccase from Myceliophthora thermophila and acetosyringone was further investigated and applied to promote the nicotinamide adenine dinucleotide (NAD(+))-dependent oxidation of glucose as well as the oxidative lactonisation of 1,4-butanediol to the corresponding -butyrolactone.
Autor/innen der BOKU Wien:
Ludwig Roland
BOKU Gendermonitor:


Find related publications in this database (Keywords)
biocatalysis
cofactors
enzyme catalysis
lactones
oxidation


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