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Gewählte Publikation:

Fruhmann, P; Mikula, H; Wiesenberger, G; Varga, E; Lumpi, D; Stöger, B; Häubl, G; Lemmens, M; Berthiller, F; Krska, R; Adam, G; Hametner, C; Fröhlich, J; .
(2014): Isolation and structure elucidation of pentahydroxyscirpene, a trichothecene fusarium mycotoxin.
J Nat Prod. 2014; 77(1):188-192 FullText FullText_BOKU

Abstract:
Pentahydroxyscirpene, a novel trichothecene-type compound, was isolated from Fusarium-inoculated rice. The structure of pentahydroxyscirpene was elucidated by 1D and 2D NMR spectroscopy and X-ray single-crystal diffraction. The conformation in solution was determined by NOESY experiments supported by quantum chemical calculations. In vitro toxicity tests showed that pentahydroxyscirpene inhibits protein synthesis as do other trichothecenes.
Autor*innen der BOKU Wien:
Adam Gerhard
Berthiller Franz
Krska Rudolf
Lemmens Marc
Varga Elisabeth
Wiesenberger Gerlinde
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