BOKU - Universität für Bodenkultur Wien - Forschungsinformationssystem
Gewählte Publikation:
Fruhmann, P; Mikula, H; Wiesenberger, G; Varga, E; Lumpi, D; Stöger, B; Häubl, G; Lemmens, M; Berthiller, F; Krska, R; Adam, G; Hametner, C; Fröhlich, J; .
(2014):
Isolation and structure elucidation of pentahydroxyscirpene, a trichothecene fusarium mycotoxin.
J Nat Prod. 2014; 77(1):188-192
FullText
FullText_BOKU
- Abstract:
- Pentahydroxyscirpene, a novel trichothecene-type compound, was isolated from Fusarium-inoculated rice. The structure of pentahydroxyscirpene was elucidated by 1D and 2D NMR spectroscopy and X-ray single-crystal diffraction. The conformation in solution was determined by NOESY experiments supported by quantum chemical calculations. In vitro toxicity tests showed that pentahydroxyscirpene inhibits protein synthesis as do other trichothecenes.
- Autor*innen der BOKU Wien:
- Adam Gerhard
- Berthiller Franz
- Krska Rudolf
- Lemmens Marc
- Varga Elisabeth
- Wiesenberger Gerlinde
- BOKU Gendermonitor:
Altmetric: