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Gewählte Publikation:

Rowan, AD; Mach, L; Mort, JS.
(1992): Antibodies to rat procathepsin B recognize the active mature enzyme.
Biol Chem Hoppe Seyler. 1992; 373(7):427-432

Use of mature cathepsin B for immunization invariably yields antisera that react with the denatured protein but not with the native enzyme. This is thought to be due to spontaneous denaturation of the immunizing antigen on introduction into the animal. R
Autor*innen der BOKU Wien:
Mach Lukas
Find related publications in this database (using NML MeSH Indexing)
Animals -
Antibodies - immunology
Antibody Specificity -
Cathepsin B - immunology
Enzyme Precursors - immunology
Hydrogen-Ion Concentration -
Immunodiffusion -
Rats -
Recombinant Proteins - immunology

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