BOKU - Universität für Bodenkultur Wien - Forschungsinformationssystem

Logo BOKU-Forschungsportal

Gewählte Publikation:

Kovac, T; Sarkanj, B; Borisev, I; Djordjevic, A; Jovic, D; Loncaric, A; Babic, J; Jozinovic, A; Krska, T; Gangl, J; Ezekiel, CN; Sulyok, M; Krska, R.
(2020): Fullerol C-60(OH)(24) Nanoparticles Affect Secondary Metabolite Profile of Important Foodborne Mycotoxigenic Fungi In Vitro
TOXINS. 2020; 12(4), 213 FullText FullText_BOKU

Despite the efforts to control mycotoxin contamination worldwide, extensive contamination has been reported to occur in food and feed. The contamination is even more intense due to climate changes and different stressors. This study examined the impact of fullerol C-60(OH)(24) nanoparticles (FNP) (at 0, 1, 10, 100, and 1000 ng mL(-1)) on the secondary metabolite profile of the most relevant foodborne mycotoxigenic fungi from genera Aspergillus, Fusarium, Alternaria and Penicillium, during growth in vitro. Fungi were grown in liquid RPMI 1640 media for 72 h at 29 degrees C, and metabolites were investigated by the LC-MS/MS dilute and shoot multimycotoxin method. Exposure to FNP showed great potential in decreasing the concentrations of 35 secondary metabolites; the decreases were dependent on FNP concentration and fungal genus. These results are a relevant guide for future examination of fungi-FNP interactions in environmental conditions. The aim is to establish the exact mechanism of FNP action and determine the impact such interactions have on food and feed safety.
Autor*innen der BOKU Wien:
Gangl Johann
Kovac Tihomir
Krska Rudolf
Krska Tamara
Sulyok Michael

Find related publications in this database (Keywords)
fullerol C-60(OH)(24)
foodborne mycotoxigenic fungi
secondary metabolism
Aspergillus spp
Fusarium spp
Alternaria spp
Penicillium spp

© BOKU Wien Impressum