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Gewählte Publikation:

Torres Acosta, JA; de Almeida Engler, J; Raes, J; Magyar, Z; De Groodt, R; Inzé, D; De Veylder, L.
(2004): Molecular characterization of Arabidopsis PHO80-like proteins, a novel class of CDKA;1-interacting cyclins.
Cell Mol Life Sci. 2004; 61(12):1485-1497 FullText FullText_BOKU

"Cyclins are regulatory proteins that interact with cyclin-dependent kinases (CDKs) to control progression through the cell cycle. In Arabidopsis thaliana, 34 cyclin genes have been described, grouped into five different types (A, B, D, H, and T). A novel class of seven cyclins was isolated and characterized in Arabidopsis, designated P-type cyclins (CYCPs). They all share a conserved central region of 100 amino acids (""cyclin box"") displaying homology to the corresponding region of the PHO80 cyclin from Saccharomyces cerevisiae and the related G1 cyclins from Trypanosoma cruzi and T. brucei. The CYCP4;2 gene was able to partially re-establish the phosphate-dependent expression of the PHO5 gene in a pho80 mutant strain of yeast. The CYCPs interact preferentially with CDKA;1 in vivo and in vitro as shown by yeast two-hybrid analysis and co-immunoprecipitation experiments. P-type cyclins were mostly expressed in proliferating cells, albeit also in differentiating and mature tissues. The possible role of CYCPs in linking cell division, cell differentiation, and the nutritional status of the cell is discussed."
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Find related publications in this database (using NML MeSH Indexing)
Amino Acid Motifs -
Amino Acid Sequence -
Arabidopsis -
Arabidopsis Proteins - chemistry
Cell Differentiation -
Cell Nucleus - metabolism
Cyclin-Dependent Kinases - chemistry
Cyclins - chemistry
Cytoplasm - metabolism
Gene Expression Regulation, Plant -
Genetic Complementation Test -
In Situ Hybridization -
Models, Biological -
Molecular Sequence Data -
Mutation -
Phosphates - chemistry
Phylogeny -
Plasmids - metabolism
Precipitin Tests -
Protein Binding -
Protein Biosynthesis -
Protein Structure, Tertiary -
RNA - chemistry
RNA, Messenger - metabolism
Repressor Proteins - chemistry
Reverse Transcriptase Polymerase Chain Reaction -
Saccharomyces cerevisiae Proteins - chemistry
Sequence Homology, Amino Acid -
Transcription, Genetic -
Two-Hybrid System Techniques -

Find related publications in this database (Keywords)
"Arabidopsis thaliana
cyclin-dependent kinase
PHO80-like protein
yeast two-hybrid"

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