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Gewählte Publikation:

Roetzer, A; Gabaldón, T; Schüller, C.
(2011): From Saccharomyces cerevisiae to Candida glabratain a few easy steps: important adaptations for an opportunistic pathogen.
FEMS Microbiol Lett. 2011; 314(1):1-9 FullText FullText_BOKU

The opportunistic human fungal pathogen Candida glabrata is closely related to Saccharomyces cerevisiae, yet it has evolved to survive within mammalian hosts. Which traits help C. glabrata to adapt to this different environment? Which specific responses are crucial for its survival in the host? The main differences seem to include an extended repertoire of adhesin genes, high drug resistance, an enhanced ability to sustain prolonged starvation and adaptations of the transcriptional wiring of key stress response genes. Here, we discuss the properties of C. glabrata with a focus on the differences to related fungi.
Autor*innen der BOKU Wien:
Schüller Christoph
Find related publications in this database (using NML MeSH Indexing)
Adaptation, Physiological -
Animals -
Candida glabrata - classification
Candidiasis - microbiology
Fungal Proteins - genetics
Gene Expression Regulation, Fungal -
Humans -
Phylogeny -
Saccharomyces cerevisiae - classification

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