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Gewählte Publikation:

Sauer, M; Mattanovich, D.
(2012): Construction of microbial cell factories for industrial bioprocesses
J CHEM TECHNOL BIOT. 2012; 87(4): 445-450. FullText FullText_BOKU

The development of industrial microbial processes is gaining unprecedented momentum. Increased concern for environmental issues and the prospect of declining petroleum resources has shifted the industrial focus increasingly to microorganisms as biocatalysts. At the same time systems biology and synthetic biology supply industry and academia with new tools to design optimal microbial cell factories. Among the tools are systems biology approaches allowing the modelling of cellular networks for rational strain design, single cell analyses methods for gaining insight into population hetereogeneity, and an exciting combination of tools from structural biology and synthetic biology, permitting the catalysis of new (unnatural) enzymatic reactions or the production of new (unnatural) chemicals. This perspective article outlines recent advances and new developments within the field of microbial cell factory design. (C) 2012 Society of Chemical Industry
Autor*innen der BOKU Wien:
Mattanovich Diethard
Sauer Michael

Find related publications in this database (Keywords)
industrial microbiology
metabolic engineering
strain improvement
systems biology
synthetic biology
metabolic modelling

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