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Gewählte Publikation:

Andreasson-Ochsner, M; Fu, Z; May, S; Xiu, LY; Nallani, M; Sinner, EK.
(2012): Selective deposition and self-assembly of triblock copolymers into matrix arrays for membrane protein production.
Langmuir. 2012; 28(4):2044-2048 FullText FullText_BOKU

Abstract:
To improve the stability of cell membrane mimics, there has been growing interest in the use of block copolymers. Here, we present an easy approach to create an array of planar polymeric matrices capable of hosting membrane proteins. The array of polymeric matrices was formed by the selective deposition of triblock copolymers onto an array of hydrophilic islands situated within a hydrophobic background. The thickness of these matrices corresponds to the length of a single polymer chain. These polymeric matrices were used to host cell-free expressed membrane proteins, and offers a prototype from which a membrane protein array can be created for diagnostics or drug discovery purposes.
Autor*innen der BOKU Wien:
Ehmoser Eva-Kathrin
BOKU Gendermonitor:

Find related publications in this database (using NML MeSH Indexing)
Animals -
Biomimetic Materials - chemistry
Cell Membrane - metabolism
Hydrophobic and Hydrophilic Interactions -
Polymers - chemistry
Receptors, Dopamine D2 - biosynthesis



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