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Foroud, NA; Baines, D; Gagkaeva, TY; Thakor, N; Badea, A; Steiner, B; Burstmayr, M; Burstmayr, H.
(2019): Trichothecenes in Cereal Grains - An Update
TOXINS. 2019; 11(11), 634 FullText FullText_BOKU

Abstract:: Trichothecenes are sesquiterpenoid mycotoxins produced by fungi from the order Hypocreales, including members of the Fusarium genus that infect cereal grain crops. Different trichothecene-producing Fusarium species and strains have different trichothecene chemotypes belonging to the Type A and B class. These fungi cause a disease of small grain cereals, called Fusarium head blight, and their toxins contaminate host tissues. As potent inhibitors of eukaryotic protein synthesis, trichothecenes pose a health risk to human and animal consumers of infected cereal grains. In 2009, Foroud and Eudes published a review of trichothecenes in cereal grains for human consumption. As an update to this review, the work herein provides a comprehensive and multi-disciplinary review of the Fusarium trichothecenes covering topics in chemistry and biochemistry, pathogen biology, trichothecene toxicity, molecular mechanisms of resistance or detoxification, genetics of resistance and breeding strategies to reduce their contamination of wheat and barley.
Authors BOKU Wien:: Bürstmayr Hermann; Bürstmayr Maria; Steiner Barbara
Find related publications in this database (Keywords): deoxynivalenol; T-2 toxin; Fusarium; Fusarium head blight (FHB); wheat; barley; resistance