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Bohm, S; Strauss, C; Stoiber, S; Kasper, C; Charwat, V.
(2017): Impact of Source and Manufacturing of Collagen Matrices on Fibroblast Cell Growth and Platelet Aggregation
MATERIALS. 2017; 10(9): FullText FullText_BOKU

Abstract:: Collagen is a main component of the extracellular matrix. It is often used in medical applications to support tissue regeneration, hemostasis, or wound healing. Due to different sources of collagen, the properties and performance of available products can vary significantly. In this in vitro study, a comparison of seven different collagen matrices derived from bovine, equine, and porcine sources was performed. As performance indicators, the scaffold function for fibroblasts and platelet aggregation were used. We found strong variation in platelet aggregation and fibroblast growth on the different collagen materials. The observed variations could not be attributed to species differences alone, but were highly dependent on differences in the manufacturing process.
Authors BOKU Wien:: Almeria Ciarra; Charwat Verena; Kasper Cornelia; Strauß Christine
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Find related publications in this database (Keywords): collagen scaffolds; fibroblasts; platelet aggregation; 3D cell culture