Selected Publication:

Schuster, B; Pum, D; Sára, M; Sleytr, UB; .
(2006): S-layer proteins as key components of a versatile molecular construction kit for biomedical nanotechnology.
Mini Rev Med Chem. 2006; 6(8):909-920 FullText FullText_BOKU

Abstract:

Surface (S)-layer proteins and S-layer fusion proteins incorporating functional sequences, self-assemble into monomolecular lattices on solid supports and on various lipid structures. Based on these S-layer proteins, supramolecular assemblies can be constructed which are envisaged for label-free detection systems, as affinity matrix, as anti-allergic immuno-therapeutics, as membrane protein-based screening devices, and as drug targeting and delivery systems.

Authors BOKU Wien:

Pum Dietmar

Schuster Bernhard

Sleytr Uwe B.

Find related publications in this database (using NML MeSH Indexing)

Anti-Allergic Agents/therapeutic use;Bacterial Proteins/chemistry*;Biomimetics*;Biosensing Techniques/methods*;Drug Delivery Systems;Drug Design;Membrane Glycoproteins/chemistry*;Molecular Structure;Nanotechnology/methods*;

Find related publications in this database (Keywords)

crystalline surface layer proteins

artificial virus

biomimetics

bottom-up strategy

S-layer fusion protein

microspheres-based detoxification system

nanobiotechnology

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