University of Natural Resources and Life Sciences, Vienna (BOKU) - Research portal
Selected Publication:
Cuomo, C.A., Güldener, U., Xu, J.R., Trail, F., Turgeon, B.G., Di Pietro, A., Walton, J.D., Ma, L.J,. Baker, S.E., Rep, M., Adam, G., Antoniw, J., Baldwin, T., Calvo, S., Chang, Y.L., Decaprio, D., Gale, L.R,. Gnerre, S., Goswami, R.S., Hammond-Kosack, K., Harris, L.J., Hilburn, K., Kennell, J.C., Kroken, S., Magnuson, J.K., Mannhaupt, G., Mauceli, E., Mewes, H.W., Mitterbauer, R., Muehlbauer, G., Münsterkötter, M., Nelson, D., O'donnell, K., Ouellet, T., Qi, W., Quesneville, H., Roncero, M.I., Seong, K.Y., Tetko, I.V., Urban, M., Waalwijk, C., Ward, T.J., Yao, J., Birren, B.W., Kistler, H.C..
(2007):
The Fusarium graminearum genome reveals a link between localized polymorphism and pathogen specialization.
SCIENCE, 317(5843), 1400-1402; ISSN 0036-8075
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- Abstract:
- We sequenced and annotated the genome of the filamentous fungus Fusarium graminearum, a major pathogen of cultivated cereals. Very few repetitive sequences were detected, and the process of repeat-induced point mutation, in which duplicated sequences are subject to extensive mutation, may partially account for the reduced repeat content and apparent low number of paralogous (ancestrally duplicated) genes. A second strain of F. graminearum contained more than 10,000 single-nucleotide polymorphisms, which were frequently located near telomeres and within other discrete chromosomal segments. Many highly polymorphic regions contained sets of genes implicated in plant-fungus interactions and were unusually divergent, with higher rates of recombination. These regions of genome innovation may result from selection due to interactions of F. graminearum with its plant hosts.
- Authors BOKU Wien:
- Adam Gerhard
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