Selected Publication:
HOHENWARTER, O; STRUTZENBERGER, K; KATINGER, H; LIEPINS, A; NOWICKY, JW.
(1992):
SELECTIVE-INHIBITION OF INVITRO-CELL GROWTH BY THE ANTITUMOR DRUG UKRAIN
DRUG EXP CLIN RES. 1992; 18: 1-4.
- Abstract:
- The inhibitory effect of Ukrain on malignant cells and on normal cells, in vitro, has been compared. To obtain a 50% inhibition of cell growth, a tenfold concentration had to be used with normal endothelial cells compared to a human osteosarcoma cell line. Hybrids of the two cell types showed nearly the same sensitivity as normal cells. A laser scanning microscope showed a high uptake of Ukrain in malignant cells, while the content in normal cells under the same experimental conditions was substantially lower.
- Authors BOKU Wien:
-
Katinger Hermann