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Selected Publication:

HOHENWARTER, O; STRUTZENBERGER, K; KATINGER, H; LIEPINS, A; NOWICKY, JW.
(1992): SELECTIVE-INHIBITION OF INVITRO-CELL GROWTH BY THE ANTITUMOR DRUG UKRAIN
DRUG EXP CLIN RES. 1992; 18: 1-4.

Abstract:
The inhibitory effect of Ukrain on malignant cells and on normal cells, in vitro, has been compared. To obtain a 50% inhibition of cell growth, a tenfold concentration had to be used with normal endothelial cells compared to a human osteosarcoma cell line. Hybrids of the two cell types showed nearly the same sensitivity as normal cells. A laser scanning microscope showed a high uptake of Ukrain in malignant cells, while the content in normal cells under the same experimental conditions was substantially lower.
Authors BOKU Wien:
Katinger Hermann



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