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Selected Publication:

Korhonen, JM; Van Hoek, AH; Saarela, M; Huys, G; Tosi, L; Mayrhofer, S; Wright, AV.
(2010): Antimicrobial susceptibility of Lactobacillus rhamnosus.
Benef Microbes. 2010; 1(1):75-80 FullText FullText_BOKU

Abstract:
We aimed to determine the minimum inhibitory concentrations (MICs) of Lactobacillus rhamnosus (n=75) strains, to study their antibiotic resistance genes with microarray, and to assess the microbiological cut-off values of tested antimicrobial agents. L. rhamnosus strains were tested with agar dilution, broth microdilution and Etest methods for ampicillin, clindamycin, erythromycin, gentamicin, streptomycin, and tetracycline using specific LSM medium. Most of the L. rhamnosus strains were found phenotypically susceptible to all six antibiotics tested. Four of the strains were phenotypically multiresistant, three strains to clindamycin, erythromycin and streptomycin and one strain to streptomycin and tetracycline. Some of the resistant (n=8) and susceptible (n=5) strains were further studied with a microarray method to reveal the antibiotic resistance genes behind the phenotypic resistances. From our experience, we recommend that microbiological cut-off values should be proposed according to the method used.
Authors BOKU Wien:
Domig Konrad
Mayrhofer Sigrid
BOKU Gendermonitor:

Find related publications in this database (using NML MeSH Indexing)
Anti-Bacterial Agents - pharmacology
Bacterial Proteins - genetics
Drug Resistance, Bacterial -
Lactobacillus rhamnosus - drug effects
Microbial Sensitivity Tests -

Find related publications in this database (Keywords)
minimum inhibitory concentration (MIC)
agar dilution
broth microdilution
Etest
microarray


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